Office of Research and DevelopmentNational Health and Environmental Effects Research Laboratory
Photo image area measures 2” H x 6.93” W and can be masked by a collage strip of one, two or three images.
The photo image area is located 3.19” from left and 3.81” from top of page.
Each image used in collage should be reduced or cropped to a maximum of 2” high, stroked with a 1.5 pt white frame and positioned edge-to-edge with accompanying images.
April 12, 2023
EPA Data from the Office of Research and DevelopmentStephen W. [email protected]
This talk does not necessarily reflect the views of the Environmental Protection Agency.
Office of Research and DevelopmentNational Health and Environmental Effects Research Laboratory, Integrated Systems Toxicology Division
One Stop Shopping for EPA Data
http://epa.gov/datafinder/
Office of Research and DevelopmentNational Health and Environmental Effects Research Laboratory, Integrated Systems Toxicology Division
Computational Toxicology Data
• Aggregated Computational Toxicology Resource (ACToR)–http://www.epa.gov/actor/
• Distributed Structure-Searchable Toxicity (DSSTox) Database–http://actor.epa.gov/actor/faces/DSSTox/Home.jsp
• Exposure foreCaster (ExpoCastTM) Database–http://www.epa.gov/ncct/expocast/
• Toxicity foreCaster (ToxCastTM) Database–http://www.epa.gov/ncct/toxcast/
• Toxicity Reference Database (ToxRefDB)–http://actor.epa.gov/toxrefdb/faces/Home.jsp
• Tox21 Collaboration (NIH, FDA)–http://www.epa.gov/ncct/Tox21/
http://epa.gov/ncct/index.html
Office of Research and DevelopmentNational Health and Environmental Effects Research Laboratory, Integrated Systems Toxicology Division
Exposure Data
• Consolidated Human Activity Database - CHAD–http://www.epa.gov/heasd/chad.html
• Consumer Product Chemical Profiles Database – CPCPDB–Coming soon to ACToR: http://www.epa.gov/actor/
• ExpoCast–http://www.epa.gov/ncct/expocast/
• Stochastic Human Exposure and Dose Simulation Model (SHEDS)– http://www.epa.gov/heasd/research/sheds.html
Office of Research and DevelopmentNational Health and Environmental Effects Research Laboratory, Integrated Systems Toxicology Division
DSS Tox
ToxCast
ExpoCastSHEDS
Virtual Tissue,Biomarker, andAdverse Outcome Pathway Knowledgebases
ToxRefDBWikiLIMS
Tox21 Data Housed at EPA
Office of Research and DevelopmentNational Health and Environmental Effects Research Laboratory, Integrated Systems Toxicology Division
Toxicological Data Shared via CEBS (NIEHS)
Proteomics Core2D Gel
Mass Spec
Metabolomics /Anal Chem Core
NMRMass Spec
ToxicoGenomics CoreMicroarray
qPCRSequencing
WikiLIMS
Many different investigators
Experimental DesignHuman, Animal, Culture
Treatment Schedule Stressor (Compound)
Assay descriptionsTimeline
Animal CareCell Culture Conditions
Sample Preparation
Laboratory/Field DataHistopathology
Clinical ChemistryIn Life Observations
Behavioral ObsDevelopmental Obs
Necropsy ObsExposure biomarkers
Exit
http://cebs.niehs.nih.gov/
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