Using Iron-rich Fertilizer to increase Hemoglobin in Rhizobium Nodules
True or false? Blood is red because of the iron in hemoglobin.
description
Transcript of True or false? Blood is red because of the iron in hemoglobin.
True or false?
Blood is red because of the iron in hemoglobin.
“Red blood cells”A close-up of red bloodcells within a capillary.
Over 99 percentof the blood vessels in the
body are capillaries,even though they only hold 5 percent of the body’s blood.
False
por·phy·rinFunction: nounEtymology: from Greek porphyra purple
-any of various compounds with a macrocyclic structure that consists essentially of four pyrrole rings joined by four =CH- groups; especially : one (as chlorophyll or hemoglobin) containing a central metal atom and usually exhibiting biological activity
How to draw a porphyrin:
Protoporphyrin IX
Glycine +Succinyl CoA
the pyrrole ring is formed
HN
R
O
aldehyde
propionic acid
pyrrole
+
N
N
HNNHΔ
R
R
R
R
The Adler synthesis of simple, symmetrically substituted porphyrins:
Meso position
R = phenyl (TPP) toluyl (TTP) p-chlorophenyl (TClPP)
The Ru-DNA Binding Project
N
N
KBr,Conc. H2SO4Conc. HNO3
95 dec C, 2.5 h
N
N
O
O
1, 10-phenanthroline 1, 10-phenanthroline-5,6-dione
N
N N
N
NH
NH
O
O
N
N O
O
N
N N
N
N
N
O
O
CH3
CH3
N
N N
N
NH
N
O
NH2
N
N N
N
N
N
NH2
NH2
H2N
H2N
NH
NH
O
O
H2N
H2N
N
N
O
O
CH3
CH3
H2N
H2N
NH
N
O
NH2
H2N
H2N
N
N
NH2
NH2
NaOH, pH ~11
MeOH, 20 h
"phen-alloxazine"
(L-allox)
"phen-dimethylalloxazine"
(L-Me2allox)
"phen-pterin" (L-pterin)
"phen-diaminopteridine"
(L-diamino)
N
N N
N
N
N
NH2H2N
H2N
N
N
NH2"phen-aminopteridine"
(L-amino)
Ligand Synthesis: Condensations are a Theme
Schiff-Base Ligands
N
N
O
N
NN
N
O
H
H
H
H
H
R
N
N
C-pterin hydrogen bonding
N
N N
N
O
N
NN
N
O
H
H
H
H
H
R
R
C-G hydrogen bonding
Watson-Crick Base Pairing
N
NN
N
O
N
N N
N
O
H
H
H
H
H
R
R
N
N N
O
H
H
H
R
N
NN
N
O
N
N N
N
O
H
H
H
H
H
R
R
N
Ru N
N
N
N
N
N
N
N
N
O
N
HH
H
Triplex DNA Base Pairing
The Ru-DNA Binding Project