BUMC Research Town Meeting:Research UpdateRonald B. Corley, Ph.D.

Associate Provost for ResearchNovember 07, 2011

NIH Funding• NIH budget currently under continuing resolution (FY 11 – 1.5%) until November 18

• NIH budget for 2012 (still anyone’s guess)– Senate appropriations committee ‐ $30. 5 billion 

• decrease of $190 million, 0.6 % from FY 2011. • $20 million to authorize the Cures Acceleration Network at NIH• creates the National Center for Advancing Translational Sciences

– House ‐ $31.7 billion• Increase of $1B, 3.3% (matches president’s request)• No mention of NCATS

• Anticipate increased discussion of changes in policies for cost recovery (direct and indirect), salary cap, etc. 

_________________________________

Grants and grants submissions_________________________________• Monthly list of foundation grants – we want 

feedback:– Too late? 2 months?– Areas not covered?– Improving navigation: hyperlinks– Web page to catalogue by month? 

• Added an “Office of Proposal Development”– Director has been recruited (Renna Lilly)– Contact: rolilly@bu.edu; 8‐4502 – Will be housed on R7

Grants and grants submissions_________________________________• New process for internally reviewing SIGs and 

SIG support (with Core Advisory Committee)– Build best case for need (and build compelling 

user base)– Space identification– Institutional support

• Pre‐proposal form: www.bu.edu/cores/sigapp

Cores (www.bumc.bu.edu/cores; www.bu.edu/cores)

• Centralization  of cores (scheduling and billing software, administrative centralization for billing (Alexis Corazzini); developing reporting

• Core Advisory Committee– Developing a process for review of existing cores– Beginning to review ideas for new cores: biostatistics/bioinformatics

– Others? : proteomics/mass spec, enzyme bank on campus, sequencing, metabolomics, etc)?

_________________________________

Cores (cont)

• Review finances of all cores (underway) – understand existing subsidies and needs

• Reviewing space utilization by cores– Consolidation of space (leveraging/sharing technical support)

• Reviewing instrumentation needs– Purchased new Aria cell sorter (Flow Core)– Helped purchase Zeiss 710 NLO 32 channel multiphoton microscope (T Haydar, L8) – new core to increase our imaging capabilities

_________________________________

Update on LASC 

• Worked with LASC (Jim Levin) and ORC to establish and engage LASC animal user groups– discuss issues of importance to the users– rates and rate changes are aired

• Discussions with MUAC ‐ ready to initiate re‐derivation of all colonies with questionable health status– Process defined– Discussing financial support and costs to investigators

_________________________________

LASC Update_________________________________• Currently undergoing a space review (Jacobs Consulting) with particular attention to: – More functional mouse housing and procedure spaces – W7,8,9 and 670

– Design and build‐out of behavioral space – M9– Increased space for USDA regulated species– Increased ABSL‐2 space– Consolidation of instrumentation (imaging, etc.)– Design plan for new zebrafish facility – R8 (currently slated to be started in mid 2012) 

_________________________________www.bumc.bu.edu/expertise

_________________________________www.bumc.bu.edu/expertise

_________________________________www.bumc.bu.edu/expertiseIf you log in, you can also search the BU asset management site (to locate equipment)

Modifying Your Profile_________________________________

please uncheckthese! Insert a research description if not prepopulated

Insert or modify key words

_________________________________

Link toyour

website!

_________________________________

Description of ProfilesChris Shanahan

_________________________________

The Oral Cancer Research InitiativeMaria Kukuruzinska

Research Web Site

• www.bumc.bu.edu/research

• Please send science photos, etc. • Please send suggestions to:

aprbumc@bu.edu

_________________________________

BUMC Multidisciplinary Research Conference_________________________________

“Nano, Metabolic and Inflammatory Routesto Cardiovascular Disease”

Wed, November 9, 3:30‐5 p.m.

Hiebert Lounge

BUMC Research Town

Meeting - 11/7/11

Profiles Research

Networking Software

Christopher Shanahan, MD MPH - Faculty Lead

Profiles RNS

• What is it?

• Why its important?

• Who is using it?

• How does it work?

• How to make work for you.

Profiles RNS: Who, What, & Why? • Who is the sponsor?

–CTSI – David Center, MD

• Who benefits? – The BU Research community

• What is it? –A powerful, user-friendly, social networking

and expertise data-mining tool

• Why use it? – Find potential collaborators & mentors –Add new expertise to your team –Reveal new directions for your research

Phase 1: Advance Deployment (Nov 9)

Phase 2: Go-Live (Dec 12)

–Training & Resource material distribution

–Faculty engagement campaign

• e-mail

• Unit presentations

• Project website

Phase 3 - Maintenance

Profiles RNS: When? (Adoption Plan)

Profiles RNS – Making it work for you

Do Nothing • Basic Demographic / Contact data pre-entered • Publication Data updated automatically

Make it even Better • For Others…

– Refine your Profile (Curation) • Add descriptions & other information • Review & update your publications

• For Yourself … – Create, maintain, & monitor your private Network

Other Institutions using Profiles RNS

VIVO – SciVal Experts – CTSI HUB Lattice Grid – CAP – Digital Vita - Loki

Search

Menu

History

Name, Affiliation, & Contact

Other Positions

Mentoring

Publications (List All or Timeline)

Concepts

Co- Authors

Similar People

Same Dept.

Physical Neighbors

Questions?

Office of the Associate Dean for Research, GSDM

650 Albany Street (X-Bldg.), Room 343 Boston, MA 02118 http://www.bu.edu/dental-research/

Oral cancer is one of the most pernicious epithelial malignancies in the world, whose incidence is on the rise. Despite progress in diagnosis and treatment of oral cancer, the 5-year survival rates over the past twenty years have remained at about 50%. Oral cancer disproportionately affects underserved minorities in the US and in developing countries. The Oral Cancer Research Initiative (OCRI) is a focused multidisciplinary collaborative that brings together basic scientists, clinicians, public health researchers, engineers, chemists and computational biologists to work on diverse issues related to oral cancer. Our mission: to elucidate the mechanisms of oral cancer development and progression and to expedite translation of research findings toward diagnosis, prevention, treatment and cure of oral cancer. Our multidisciplinary effort will align research on oral cancer with societal needs.

Basic Genetics/ Genomics Clinical

Biomedical Engineering Translational

Public Health

Drivers & Pathways

Biomarkers Stem Cells

Infection-Associated

Cancers Metabolism

Surgery Radiology Pathology Prevention Epidemiology

M. Kukuruzinska (M&CB)

W. Cardoso (BUSM, Pulmonary)

P. Trackman (P&OB)

X. Varelas (BUSM, Biochem.)

D. Seldin (BUSM, Hem Onc)

S. Amar (P&OB) D. Levin (M&CB)

M. Trojanowska (BUSM, Arthritis

Center)

F. Oppenheim (P&OB)

G. Huang (Endodontics) K. Applebaum

(SPH) A. Spira (BUSM,

Computational Biomedicine)

C. Genco (BUSM, Microbio.)

D. Anderson (BUSM, Microbio.)

K. Applebaum (SPH)

B. Corkey (High Throughput

Screening, Metabolism)

(BUSM, Medicine) N. Istfan (BUSM,

Endocrinology)

S. Jalisi (BUSM, Surg. Onc.)

P. Mehra (OMS)

A. Salama (OMS)

O. Sakai (BUSM, Radiology)

V. Noonan (O&M Path.)

Y. Wu (General Dentistry)

D. Bowen (SPH)

J. Jones (Gen. Dent., VA)

M. McClean (SPH)

K. Applebaum (SPH)

Clinical Research Center (CRC) Evans Center for Interdisciplinary Biomedical Research

Affinity Research Collaboratives (ARCs), BUSM (K. Ravid)

A. Spira (BUSM, Computational

Biomedicine) M. Platt

(BUSM, Otolaryngology)

R. Pistey (Biospecimen Archive

Research Core)

B. Goldberg M. Cabodi

S. Unlu Center for Nanoscience & Nanobiotechnology

CTSI W. Adams

(Informatics/i2b2) J. Porco

(Center for Chemical Methodology & Library

Development) Office of Technology Development (OTD)

D. Fournier (CTSI, Program

Evaluation)

Center for Global Health &

Development B. Brown S. Buquor

Rhoda M. Alani, M.D. Herbert Mescon Professor & Chair, Department of Dermatology, School of Medicine David M. Center, M.D. Chief, Pulmonary, Allergy & Critical Care Medicine Gordon & Ruth Snider Professor of Pulmonary Medicine Professor of Medicine & Biochemistry Associate Provost for Translational Research Director, Boston University Medical Campus Translational Research Institute David L. Coleman, M.D. Wade Professor & Chair, Department of Medicine

Internal Advisory Board Ronald B. Corley, Ph.D. Professor & Chair of Microbiology Associate Provost for Research, Boston University Medical Campus Jeffrey W. Hutter, D.M.D., M.Ed. Dean, Henry M. Goldman School of Dental Medicine Spencer N. Frankl Professor in Dental Medicine Katya Ravid, D.Sc., Ph.D. Professor of Medicine & Biochemistry Director, Evans Center for Interdisciplinary Biomedical Research Roberta F. White, Ph.D. Associate Dean for Research Professor of Environmental Health, School of Public Health

Thomas J. Glynn, Ph.D. Director, Cancer Science & Trends Director, International Cancer Control, American Cancer Society

Jennifer Grandis, M.D. Director, Head & Neck SPORE Professor of Otolaryngology, University of Pittsburgh

Scott M. Lippman, M.D. Director, Head & Neck SPORE Chair, Thoracic/Head & Neck Medical Oncology University of Texas MD Anderson Cancer Center

Poul Erik Petersen, D.D.S., D.O.Sc., M.Sc. Chief, Oral Health Programme, World Health Organization

Marshall Posner, M.D. Director, Head & Neck Medical Oncology Director, Office of Cancer Clinical Trials The Tisch Cancer Institute Mount Sinai School of Medicine

External Advisory Board Jatin P. Shah, M.D., F.A.C.S. Chairman of the Council of the International Academy of Oral Oncology Professor of Surgery, Cornell University Chief of Head & Neck Surgery Service, Memorial Sloan-Kettering Cancer Center Dong M. Shin, M.D., F.A.C.P. Director, Head & Neck SPORE Professor of Hematology, Oncology & Otolaryngology Director, Clinical & Translational Cancer Prevention Program Winship Cancer Institute Emory University School of Medicine Gregory T. Wolf, M.D. Director, Head & Neck SPORE Professor of Otolaryngology, University of Michigan

Oral Cancer Research Initiative: Organizational Meeting

Wednesday, November 16, 2011 Evans Seminar Room 112A 2:00P.M. - 3:30P.M.

Organize focused research teams working on different aspects of oral cancer;

Spearhead responses to funding opportunities from federal and private sources:

• SPOREs • P01s • Private Foundations (American Cancer Society) • Affinity Research Collaboratives (ARCs)

Capitalize on existing resources and identify new partnerships.

Next…

Mission: The CRC supports collaborations among clinical, public health and basic science researchers to study oral and systemic conditions. It provides new research opportunities for faculty, postdoctoral researchers, residents, as well as graduate and undergraduate students. The CRC will: • provide clinical researchers with access to patients for studies of

oral conditions and diseases, as well as oral complications of systemic diseases;

• facilitate collection of tissue specimens from the oral cavity including saliva, pellicle, scalpel and brush biopsies and swabs of oral mucosa.

*The CRC has received partial support for its operations from the CTSI.

Clinical Research Center (CRC)

650 Albany Street (X-Bldg., Rm. 343) Boston University

Henry M. Goldman School of Dental Medicine Boston, MA 02118

Barbara Pyke, Executive Director, OCRI bpyke@bu.edu | 617-414-1014 Kristina Roman, Communications Manager, OCRI kayroman@bu.edu | 617-414-1028

Office of the Associate Dean for Research

http://www.bu.edu/dental-research/