Bulletin 36.2

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8th

August, 2014 Volume No.: 36 Issue No.: 02

Vision

TO REACH THE PINNACLE OF GLORY AS A CENTRE OF EXCELLENCE IN THE OF PHARMACEUTICAL AND BIOLOGICAL SCIENCES BY KNOWLEDGE BAS

LEARNING AND PRACTICE

ontentsMessage from PRINCIPAL

Editorial board

Historical article

News Update

Knowledge based Article

Disease Related Breaking

News

Upcoming Events

Drugs Update

Campus NewsStudents Section

Editors Note

Archive

GNIPST Photo Gallery

or your comments/contribution

For ack-Issues,

ailto:[email protected]

GURU NANAK INSTITUTE OF PHARMACEUTICAL

SCIENCE AND TECHNOLOGY

Website: http://gnipst.ac.in
https://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=7mailto:[email protected]:[email protected]:[email protected]://plus.google.com/u/0/photos/111714720327580099858/albums/5897323676427099873?sort=7

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MESSAGE FROM PRINCIPAL

"It can happen. It does happen.

But it can't happen if you quit." Lauren Dane.

We are what we repeatedly do.

Excellence then is not an act, but a habit. Aristotle

It gives me immense pleasure to pen a few words for our e-bulletin. At the onset I would like to thank t

last years editors and congratulate the newly selected editors for the current year.

Our first consideration is always in the best interest of the students. Our goal is to promote academexcellence and continuous improvement.

I believe that excellence in education is aided by creating a learning environment in which all learners a

supported in maximizing their potential and talents. Education needs to focus on personalized learni

and instruction, while promoting an education system that is impartial, universally accessible, and meetin

the needs of all students.

It is of paramount importance that our learners have sufficient motivation and encouragement in order

achieve their aims. We are all very proud of you, our students, and your accomplishments and lo

forward to watching as you put your mark on the profession in the years ahead.

The call of the time is to progress, not merely to move ahead. Our progressive Management is looki

forward and wants our Institute to flourish as a Post Graduate Institute of Excellence. Steps are taken

this direction and fruits of these efforts will be received by our students in the near future. Our Teache

are committed and dedicated for the development of the institution by imparting their knowledge and pl

the role of facilitator as well as role model to our students.

The Pharmacy profession is thriving with a multitude of possibilities, opportunities and positi

challenges. At Guru Nanak Institute of Pharmaceutical Science and Technology, our focus is on holis

needs of our students.

I am confident that the students of GNIPST will recognize all the possibilities, take full advantage of th

opportunities and meet the challenges with purpose and determination.

Excellence in Education is not a final destination, it is a continuous walk. I welcome you to join us

this path.

My best wishes to all.

Dr. A. Sengupta

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EDITORIAL BOARD

CHIEF EDITOR DR. ABHIJIT SENGUPTAEDITOR MS. JEENATARA BEGUM

ASSOCIATE EDITOR MR. DIPANJAN MANDAL

HISTORICAL ARTICLE

Theophrastus Father of BotanyTheophrastus (about 300 B.C.), among the greatest early Greek

philosophers and natural scientists, is called the "father of botany."

His observations and writings dealing with the medical qualitiesand peculiarities of herbs are unusually accurate, even in the light

of present knowledge. He lectured to groups of students who

walked about with him, learning of nature by observing her

treasurers at firsthand. In his hands he holds a branch of

belladonna. Behind him are pomegranate blooms, senna, and

manuscript scrolls. Slabs of ivory, coated with colored beeswax,

served the students as "slates." Writing was cut into the surfacewith a stylus.

NEWS UPDATE

Gene increases risk of breast cancer to one in

three by age 70: (7thAugust, 2014)Medical researchers have studied breast cancer risks for one of

potentially the most important genes associated with breastcancer after the BRCA1/2 genes. Women with mutations in the

PALB2 gene have on average a one in three chance of developing

breast cancer by the age of 70.

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Link between vitamin D, dementia risk

confirmed: (6thAugust, 2014)Vitamin D deficiency is associated with a substantially increased

risk of dementia and Alzheimer's disease in older people, according

to the most robust study of its kind ever conducted. An

international team found that study participants who were

severely vitamin D deficient were more than twice as likely to

develop dementia and Alzheimer's disease.

Behavior-focused therapies help children with

autism: (6th

August, 2014)Benefits of behavior-focused therapies for children with autismspectrum disorder (ASD) have been reported by researchers. The

review updates a prior systematic review of interventions for

children (up to age 12) with a focus on recent studies of behavioral

interventions.

Brain tumors fly under body's radar like stealth

jets: (6th

August, 2014)Brain tumors fly under the radar of the bodys defense forces bycoating their cells with extra amounts of a specific protein, newresearch shows. Like a stealth fighter jet, the coating means thecells evade detection by the early-warning immune system thatshould detect and kill them.

Gene-editing technique offers new way to model

cancer: (6thAugust, 2014)A new gene-editing technique allows scientists to more rapidlystudy the role of mutations in tumor development. "Thesequencing of human tumors has revealed hundreds of oncogenesand tumor suppressor genes in different combinations. Theflexibility of this technology, as delivery gets better in the future,

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will give you a way to pretty rapidly test those combinations,"explained an author of the paper.

Bone tumour destroyed using incisionless

surgery: First in North American child: (6th

August, 2014)A Canadian child is the first in North America to have undergone aspecialized procedure that uses ultrasound and magneticresonance imaging (MRI) to destroy a tumor in his leg withoutpiercing the skin. Doctors used an MRI to guide high-intensityultrasound waves to destroy a benign bone tumor called osteoidosteoma. The lesion had caused 16-year-old Jack Campanile

excruciating pain for a year prior to the procedure. By the time hewent to bed that night, the athletic teen experienced completepain relief.

Most kids with blunt torso trauma can skip the

pelvic X-ray: (6thAugust, 2014)Pelvic x-rays ordered as a matter of course for children who havesuffered blunt force trauma do not accurately identify all cases ofpelvic fractures or dislocations and are usually unnecessary for

patients for whom abdominal/pelvic CT scanning is otherwiseplanned. A study casts doubt on a practice that has beenrecommended by the Advanced Trauma Life Support Program,considered the gold standard for trauma patients.

Molecular competition drives adult stem cells to

specialize, study shows: (6thAugust, 2014)Adult organisms ranging from fruit flies to humans harbor adultstem cells, some of which renew themselves through cell divisionwhile others differentiate into the specialized cells needed toreplace worn-out or damaged organs and tissues. Understandingthe molecular mechanisms that control the balance between self-renewal and differentiation in adult stem cells is an important

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foundation for developing therapies to regenerate diseased, injuredor aged tissue.

Discovery about wound healing key to

understanding cell movement: (6th

August, 2014)Research by a civil engineer is helping shed light on the waywounds heal and may someday have implications forunderstanding how cancer spreads, as well as why certain birthdefects occur.

New hand-held device uses lasers, sound waves

for deeper melanoma imaging: (6thAugust, 2014)Melanoma is the deadliest form of skin cancer, causing more than

75 percent of skin-cancer deaths. The thicker the melanoma tumor,the more likely it will spread and the deadlier it becomes. Now, ateam of researchers has developed a new hand-held device thatuses lasers and sound waves that may change the way doctorstreat and diagnose melanoma. The tool is ready forcommercialization and clinical trials.

For detail mail toeditor

KNOWLEDGE BASED ARTICLE

OsteoarthritisOsteoarthritis is a joint disease that most often affects middle-age

to elderly people. It is commonly referred to as OA or as "wear and

tear" of the joints, but OA is a disease of the entire joint, involving

the cartilage, joint lining, ligaments, and bone. Although it is more

common in older people, it is not really accurate to say that thejoints are just wearing out.

About 27 million Americans are living with OA, the most common

form of joint disease. The lifetime risk of developing OA of the knee

is about 46%, and the lifetime risk of developing OA of the hip is

25%. OA is the most common form of joint disease, and is a leading

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cause of disability in elderly people. This arthritis tends to occur in

the hand joints, spine, hips, knees, and great toes. It is

characterized by breakdown of the cartilage (the tissue that

cushions the ends of the bones between joints), bony changes of

the joints, deterioration of tendons and ligaments, and various

degrees of inflammation of the synovium (joint lining). Though

some of the joint changes are irreversible, most patients will not

need joint replacement surgery. OA symptoms (what you feel) can

vary greatly among patients. A rheumatologist can detect arthritis

and prescribe the proper treatment. OA is a frequently slowly

progressive joint disease typically seen in middle-aged to elderly

people. The disease occurs when the joint cartilage breaks downoften because of mechanical stress or biochemical alterations,

causing the bone underneath to fail. OA can occur together with

other types of arthritis, such as gout or rheumatoid arthritis. OA

tends to affect commonly used joints such as the hands and spine,

and the weight-bearing joints such as the hips and knees.

Symptoms:

Joint pain and stiffnessKnobby swelling at the joint

Cracking or grinding noise with joint movement

Decreased function of the joint

Risk factors include:

Older age

Having family members with OA

ObesityJoint injury or repetitive use (overuse) of joints

Joint deformity such as unequal leg length, bowlegs or knocked

knees

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Diagnosis:

Most often doctors detect OA based on the typical symptoms

(described earlier) and on results of the physical exam. In some

cases, X-rays or other imaging tests may be useful to tell the extentof disease or to help rule out other joint problems.

Treatment:

There is no proven treatment yet that can reverse joint damage

from OA. The goal of treatment is to reduce pain and improve

function of the affected joints. Most often, this is possible with a

mixture of physical measures and drug therapy and, sometimes,

surgery.Physical measures: Weight loss and exercise are useful in OA.

Excess weight puts stress on your knee joints and hips and low

back. For every 10 pounds of weight you lose over 10 years, you can

reduce the chance of developing knee OA by up to 50%. Exercise

can improve your muscle strength, decrease joint pain and

stiffness, and lower the chance of disability due to OA.

Also helpful are support (assistive) devices, such as braces or a

walking cane, that help you do daily activities. Heat or coldtherapy can help relieve OA symptoms for a short time.

Certain alternative treatments such as spa (hot tub), massage,

acupuncture and chiropractic manipulation can help relieve pain

for a short time. They can be costly, though, and require repeated

treatments. Also, the long-term benefits of these alternative

(sometimes called complementary or integrative) medicine

treatments are unproven but are under study.Drug therapy: Forms of drug therapy include topical, oral (by

mouth) and injections (shots). You apply topical drugs directly on

the skin over the affected joints. These medicines include capsaicin

cream, lidocaine and diclofenac gel. Oral pain relievers such as

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acetaminophen are common first treatments. So are nonsteroidal

anti-inflammatory drugs (often called NSAIDs), which decrease

swelling and pain.

In 2010, the government (FDA) approved the use of duloxetine

(Cymbalta) for chronic (long-term) musculoskeletal pain

including from OA. This oral drug is not new. It also is in use for

other health concerns, such as mood disorders, nerve pain and

fibromyalgia.

Patients with more serious pain may need stronger medications,

such as prescription narcotics.

Joint injections with corticosteroids (sometimes called cortisone

shots) or with a form of lubricant called hyaluronic acid can givemonths of pain relief from OA. This lubricant is given in the knee,

and these shots may help delay the need for a knee replacement by

a few years in some patients.

Surgery: Surgical treatment becomes an option for severe cases.

This includes when the joint has serious damage, or when medical

treatment fails to relieve pain and you have major loss of function.

Surgery may involve arthroscopy, repair of the joint done throughsmall incisions (cuts). If the joint damage cannot be repaired, you

may need a joint replacement.

Supplements: Many over-the-counter nutrition supplements have

been used for treatment of OA. Most lack good research data to

support their effectiveness and safety. Among the most widely

used are glucosamine/chondroitin sulfate, calcium and vitamin D,

and omega-3 fatty acids. To ensure safety and avoid druginteractions, consult your doctor or pharmacist before using any of

these supplements. This is especially true when you are combining

these supplements with prescribed drugs.

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DISEASE RELATED BREAKING NEWS

Ebola virus disease, West Africa (4thAugust,

2014)

Between 31 July and 1 August 2014, a total of 163 new cases of

Ebola virus disease (EVD; laboratory-confirmed, probable, and

suspect cases) as well as 61 deaths were reported from Guinea,

Liberia, Nigeria, and Sierra Leone. Three of these cases are in

Nigeria and include two new probable cases one is a health-

care worker and one is a Nigerian who travelled to Guinea and a suspected case in a nurse.

National authorities in Ghana, Nigeria, and Togo continue to

work closely with WHO and its partners in identification of

contacts and contact tracing as well as in preparing response

plans as a result of the recent visit by and death of a Liberian

national to Nigeria from EVD and the new Nigerian EVD

probable case, who travelled to Guinea.Read more

UPCOMING EVENTS

5thInternational Conference on Stem Cells and Cancer 2014, JNU

Convention Centre, New Delhi, India from 8-10 November, 2014

DRUGS UPDATES

FDA Approves Orbactiv: (6thAugust, 2014)The U.S. Food and Drug Administration approved Orbactiv

(oritavancin), a new antibacterial drug to treat adults with skin

infections. Orbactiv is approved to treat patients with acute

bacterial skin and skin structure infections (ABSSSI) caused by

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http://www.who.int/csr/don/2014_08_04_ebola/en/http://www.who.int/csr/don/2014_08_04_ebola/en/http://www.who.int/csr/don/2014_08_04_ebola/en/http://d/Jeenat/Bulletin%2034.3_1/New%20Folder/UPCOMING%20EVENTS.docxhttp://d/Jeenat/Bulletin%2034.3_1/New%20Folder/UPCOMING%20EVENTS.docxhttp://www.who.int/csr/don/2014_08_04_ebola/en/

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certain susceptible bacteria, including Staphylococcus aureus

(including methicillin-susceptible and methicillin-resistant

strains), various Streptococcus species and Enterococcus faecalis.

Orbactiv is administered intravenously.Read more

CAMPUS NEWS

We congratulate the following M.Pharm. final year students whohave made their positions in different pharmaceutical companies.Anirban Banerjee (Emami Ltd.)Mahender Roy (Stadmed private Ltd.)

We congratulate the following B.Pharm. final year students for

their success.Samadrita Mukherjee (Abbott India Ltd.)Suman Sarkar (Tata Medical Centre-Apollo Pharmacy)Shrewashee Mukherjee (Fresenius Kabi-Parenteral Nutrition)Avishek Naskar (Glaxo SmithKline-Marketing)Bappaditya Manik (USV Limited)Sarbani Das (Nutri Synapzz-Marketing)Ankita Roy (Nutri Synapzz-Marketing)

Rahul Mitra (B M Pharmaceuticals-Production)The following B.Pharm. final year students have qualified, GPAT-

2014. We congratulate them all.Utsha SinhaSatarupa BhattacharyaSandipan SarkarPurbali Chakraborty

Reminiscence, 2014(GNIPST Reunion) was held in College

campus on 2nd

February,2014.1st Annual Sports of GNIPST was held on 3rd February,2014 in

College campus ground.

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http://www.drugs.com/newdrugs/fda-approves-orbactiv-oritavancin-skin-skin-structure-infections-4066.htmlhttp://www.drugs.com/newdrugs/fda-approves-orbactiv-oritavancin-skin-skin-structure-infections-4066.htmlhttp://www.drugs.com/newdrugs/fda-approves-orbactiv-oritavancin-skin-skin-structure-infections-4066.htmlhttp://www.drugs.com/newdrugs/fda-approves-orbactiv-oritavancin-skin-skin-structure-infections-4066.html

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An industrial tour and biodiversity tour was conducted in Sikkimfor B.Pharm and B.Sc. students under the supervision of Mr. Asis

Bala, Ms. Jeentara Begum and Ms. Moumita Chowdhury.

B.Pharm 3rd

year won the GNIPST Football Champions trophy,2013. B.Pharm 3rdyear won the final match 1-0 against B.Pharm 2nd

year. Deep Chakrabortywas the only scorer of the final.

STUDENTS SECTION

WHO CAN ANSWER FIRST????

Reid hoffmen is the founder of which

organisation?

David Adriaan van Dorp and Jozef

Ferdinand Arens first synthesized which

chemical entity?Answer of Previous Issues Questions

A) Yonex Co., Ltd. is a Japanese manufacturer ofsporting

equipment forbadminton,golf, and tennis,

producingracquets,clubs,shoes,shuttlecocks, and other equipment for those

sports.

B)Twitter

Identify the person

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http://en.wikipedia.org/wiki/David_Adriaan_van_Dorphttp://en.wikipedia.org/wiki/Sports_equipmenthttp://en.wikipedia.org/wiki/Sports_equipmenthttp://en.wikipedia.org/wiki/Badmintonhttp://en.wikipedia.org/wiki/Golfhttp://en.wikipedia.org/wiki/Tennishttp://en.wikipedia.org/wiki/Racquethttp://en.wikipedia.org/wiki/Golf_club_(equipment)http://en.wikipedia.org/wiki/Shoe#Athletichttp://en.wikipedia.org/wiki/Shuttlecockhttp://en.wikipedia.org/wiki/Shuttlecockhttp://en.wikipedia.org/wiki/Shoe#Athletichttp://en.wikipedia.org/wiki/Golf_club_(equipment)http://en.wikipedia.org/wiki/Racquethttp://en.wikipedia.org/wiki/Tennishttp://en.wikipedia.org/wiki/Golfhttp://en.wikipedia.org/wiki/Badmintonhttp://en.wikipedia.org/wiki/Sports_equipmenthttp://en.wikipedia.org/wiki/Sports_equipmenthttp://en.wikipedia.org/wiki/David_Adriaan_van_Dorp

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Answer of Previous Issues Image

Jack Dorsey

Send your thoughts/

Quiz/Puzzles/games/write-ups or any other

contributions for Students Section

answ ers of this Section at

[email protected]

EDITORS NOTE

It is a great pleasure for me to publish the 2nd

issue of 36th

Volume

of GNIPST BULLETIN. All the followers of GNIPST BULLETIN

are able to avail the bulletin through facebook account GNIPST

bulletin I am very much thankful to all the GNIPST members and

readers who are giving their valuable comments, encouragements

and supports. I am also thankful to Dr. Abhijit Sengupta, Director

of GNIPST for his valuable advice and encouragement. Special

thanks to Dr. Prerona Saha, Mr. Debabrata Ghosh Dastidar

and Mr. Soumya Bhattacharya for their kind co-operation andtechnical supports. Thank you Mr. Soumya Bhattacharyafor the

questionnaires of the student section. An important part of the

improvement of the bulletin is the contribution of the readers. You

are invited to send in your write ups, notes, critiques or any kind of

contribution for the forthcoming special and regular issue.

ARCHIVE

Students of GNIPST organized pre puja celebrationprogramme, Saaranya on 7th October, 2013 in college

Auditorium.

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GNIPST organized a garment distribution programmeon 28thSeptember, 2013 at Dakshineswar Kali Temple and Adyapith,

Kolkata. On this remarkable event about hundred people have

received garments. More than hundred students and most ofthe faculties participated on that day with lot of enthusiasm.

GNIPST celebrated World Heart Day (29thSeptember) andPharmacists Day (25th September) on 25th and 26th

September, 2013 in GNIPST Auditorium. A seminar on

Violence against woman and female foeticide was held on

GNIPST Auditorium on 25thSeptember organized by JABALA

Action Research Organization. On 26th September an intra-

college Oral and Poster presentation competition related to

World Pharmacists day and Heart day was held in GNIPST.

Ms. Purbali Chakraborty of B.Pharm 4th year won the first

prize in Oral Presentation. The winner of Poster presentation

was the group of Ms. Utsa Sinha, Mr. Koushik Saha and Mr.

Niladri Banerjee (B.Pharm 4th year). A good number of

students have participated in both the competition with theirvaluable views.

Teachers daywas celebrated on 5thSeptember, 2013 by

the students of GNIPST in GNIPST Auditorium.

A zalea exotic flower ) , the fresher welcome programme

for newcomers of GNIPST in the session 2013-14 was held on8th August in GNIPST Auditorium.

One day seminar cum teachers development programme forschool teachers on the theme of Recent Trends of Life

Sciences in Higher Educationorganized by GNIPST held on

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29th June, 2013 at GNIPST auditorium. The programme was

inaugurated by Prof . Asit Guha, Director of JIS Group, Mr.

U.S. Mukherjee, Dy Director of JIS Group and Dr. Abhijit

Sengupta, Director cum Principal of GNIPST with lamp

lighting. The programme started with an opening song

performed by the B.Pharm students of this institute. The

seminar consists of a series of lectures, video presentations and

poster session. On the pre lunch session 4 lectures were given

by Dr. Lopamudra Dutta, Mr. Debabrata Ghosh Dastidar, Ms.

Swati Nandy and Ms. Tamalika Chakraborty respectively. On

their presentation the speakers enlighten the recent

development of Pharmacy, Genetics and Microbiology andtheir correlation with Life Sciences. On the post lunch session,

Ms. Saini Setua and Ms. Sanchari Bhattacharjee explained the

recent development and career opportunities in Biotechnology

and Hospital Management. The programme was concluded

with valedictory session and certificate distribution.

About 50 Higher secondary school teachers from different

schools of Kolkata and North& South 24 Parganas district ofWest Bengal participated in this programme. A good

interactive session between participants and speakers was

observed in the seminar. The seminar was a great success with

the effort of faculties, staffs and students of our Institute. It was

a unique discussion platform for school teachers and

professional of the emerging and newer branches of Life

Science.

The general body meeting of APTI, Bengal Branch has been

conducted at GNIPST on 15th June, 2012. The program started

with a nice presentation by Dr. Pulok Kr. Mukherjee, School of

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Natural Products, JU on the skill to write a good manuscript

for publication in impact journals. It was followed by nearly

two hour long discussion among more than thirty participants

on different aspects of pharmacy education. Five nonmember

participants applied for membership on that very day.

GNIPST is now approved by AICTE and affiliated to WBUT

for conducting the two years post graduate course (M.Pharm)

in P H A R M A C O L O G Y .The approved number of seat is 18.

The number of seats in B.Pharm. has been increased from 60 to

120.

AICTE has sanctioned a release of grant under Research

Promotion Scheme (RPS) during the financial year 2012-13to

GNIPST as per the details below:

a. Beneficiary Institution: Guru Nanak Institution of

Pharmaceutical Science & Technology.

b.Principal Investigator:Dr. LopamudraDutta.

c. Grant-in-aid sanctioned:Rs. 16,25000/- onlyd. Approved duration: 3 years

e. Title of the project: Screening and identification of

potential medicinal plant of Purulia & Bankura districts of

West Bengal with respect to diseases such as diabetes,

rheumatism, Jaundice, hypertension and developing

biotechnological tools for enhancing bioactive molecules in

these plants.

Bulletin 36.2

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