Athrogenic muscle inhibition (AMI) • What is AMI and what ...

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1 Anil Bhave, PT Director Gait Laboratory Clinical Director Orthopedic Rehabilitation Rubin Institute of Advanced Orthopedics Sinai Hospital, Baltimore, Maryland Muscle Activation deficits Athrogenic muscle inhibition (AMI) • What is AMI and what causes it? Bhave 2017 Simple formula Bhave 2017 Quadriceps Arthrogenic Muscle Inhibition: Neural Mechanisms and Treatment Perspectives David Andrew Rice, BHSc,* and Peter John McNair, PhD† Conclusions: AMI remains a significant barrier to effective rehabilitation in patients with arthritis and following knee injury and surgery. Gaining a better understanding of AMI’s underlying mechanisms will allow the development of improved therapeutic strategies, enhancing the rehabilitation of patients with knee joint pathology. Arthrogenic muscle Inhibition Pain Joint effusion Age (Central activation deficit) Instability Habitual Limp leads to quads avoidance gait Bhave 2017 Bhave 2017

Transcript of Athrogenic muscle inhibition (AMI) • What is AMI and what ...

Page 1: Athrogenic muscle inhibition (AMI) • What is AMI and what ...

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Anil Bhave, PTDirector Gait LaboratoryClinical Director Orthopedic RehabilitationRubin Institute of Advanced OrthopedicsSinai Hospital, Baltimore, Maryland

Muscle Activation deficitsAthrogenic muscle inhibition

(AMI)

• What is AMI and what causes it?

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Simple formula

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Quadriceps Arthrogenic Muscle Inhibition:Neural Mechanisms and Treatment PerspectivesDavid Andrew Rice, BHSc,* and Peter John McNair, PhD†

Conclusions: AMI remains a significant barrier to effective rehabilitation in patients with arthritis and following knee injury and surgery. Gaining a better understanding of AMI’s underlying mechanisms will allow the development of improved therapeutic strategies, enhancing the rehabilitation of patients with knee joint pathology.

Arthrogenic muscle Inhibition

• Pain

• Joint effusion

• Age (Central activation deficit)

• Instability

• Habitual Limp leads to quads avoidance gait

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CAR (Central Activation Ratio)Age related

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Mechanisms Undlerlying Quadriceps Weakness in KneeOsteoarthritisSTEPHANIE C. PETTERSON1,2, PETER BARRANCE3, THOMAS BUCHANAN4, STUARTBINDER-MACLEOD2, and LYNN SNYDER-MACKLER

Med Sci Sports March 2008

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Habitual limp

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Knee Flexion Lever Arm

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What about touniquet?

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EMG changes in 18/25 patients post menisectomy

• EMG changes temporary

• 16/18 resolved in 6 months

• Direct correlation exists between EMG abnormality and duration of tourniquet inflation and patient’s recovery time

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Does Tourniquet Use in TKA Affect Recovery of Lower Extremity Strength and Function? A

Randomized Trial.Dennis DA1, Kittelson AJ, Yang CC, Miner TM, Kim

RH, Stevens-Lapsley JE.

• Quad weakness 11.3 Nm for 3 months

• No effect on hamstrings

• Small difference in blood loss

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Effects of tourniquet use on quadriceps function and pain in total knee arthroplasty.

Liu D1, Graham D2, Gillies K3, Gillies RM4.Knee Surg Relat Res. 2014 Dec;26(4):207-13. doi:

10.5792/ksrr.2014.26.4.207. Epub 2014 Dec 2

• Increased pain in tourniquet group

• No difference in ROM, strength, Oxford Knee score

• Quad strength compromised up to 6 months as studied by surface EMG

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Bottom line about tourniquet?

• More than 2 hours

• Max optimal pneumatic pressure 270 to 290 mm/hg

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What are the long term effects of AMI

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Functional problems after TKA

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Quadriceps strength 98 OA (55 to 72 yrs.) compared to Fearon F (1989) data on 79

asymptomatic patients

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Male OA Malenormal

Female OA Femalenormal

Male OA

Male normal

Female OA

Female normal

(Force/BW)*100Bhave 2017

Difficulty in post TKA patients  ( 661 patients 1‐4 year f/u

% of patients with difficulty

Limp or difficulty in gait 53%

Difficulty with stairs 54%

Difficulty getting out of car 38%

Difficulty getting out of chair 31%

Difficulty in participating in recreational activity 50%

Stiffness and pain 41%

Clin Orthop Relat Res. 2014 Jan;472(1):133-7.

High level of residual symptoms in young patients after total knee arthroplasty.Parvizi J, Nunley RM, Berend KR, Lombardi AV Jr, Ruh EL, Clohisy JC, Hamilton WG, Della Valle CJ, Barrack R

Need for prehabilitation and rehabilitation in TKA 

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The Effect of a Prehabilitation Exercise Program on Quadriceps Strength for Patients Undergoing Total Knee Arthroplasty: A Randomized Controlled Pilot StudyCarly McKay, PhD, Harry Prapavessis, PhD, Timothy Doherty, PhDAmerican Academy of Physical Medicine and Rehabilitation1934‐1482/12/$36.00 Vol. 4, 647‐656, September 2012

Brace patients

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Brace and NMESCohort

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Use of Extension assist brace post TKA

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NMES How strong

Maximally tolerated

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Physical Therapist

•Can we be Masters of Disasters?

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Need to innovate

because routine did not work well

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Case 1

Arthrogenic muscle inhibition with ROM

deficit

June 2013

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PCL, LCL,MCL complete and partial ACL rupture

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Post reconstruction Infection

August 2013

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Post Infection contracture

December 2013

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Bracing and Therapy protocol

• EXT guardian brace all day long

• Removable extension splint all night

• PT 1-2 times a week

• NMES at home 2 times day in bed

• Hip strengthening in brace

• WALKING in guardian brace two crutches to one crutch to no device

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CKD +Sport EXT

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Full extension

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PT ROM Progress

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Transitioned to Guardian sports brace and

Sports specific PT

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PT progress

May 2014

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Return to non contact sports

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Sports specific perfomance

• Strength equal to the opposite side (Isokinetic testing)

• Single hop for distance with in 5 cms of normal

• Full ROM• Lateral jump equal to opposite

side Bhave 2017

Return to non contact sports

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Case 2 Valgus knee deformity

beware of peroneal nerve

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Post CKD and PT

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Happy Patient

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Case 4Congenital Knee flexion

contracture

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Custom solution

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Improved Gait

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Case 5: Knee Flexion Contracturewith Grade 2 Quads

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Initial Rx

• BoNT –A , Hamstrings.

• Serial casting 1 week X 2.

• PT started 2 times a week after serial cast removal.

• Home NMES Unit

• Once a week TDN/IMT

• Walking brace fitting 2 weeks after PT start.

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Initial brace fitting400 KFC, 350 Quad Lag

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Patient with 25° of knee flexion contracture andGrade 3- quadriceps strength with 40°active extension lag

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Patient with 15° of Knee flexion contracture andGrade 3- quadriceps strength with 40° active extension lag

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Thank You

[email protected]@lifebridgehealth.org

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