Academy Speaks Again - Texas A&M...
18
Academy Speaks Again ‘Plasmas & Possibilities’ Dr. Magesh Thiyagarajan Director of Plasma Engineering Research (PERL) Assistant Professor of Engineering School of Engineering & Computing Sciences College of Science and Engineering Texas A&M University – Corpus Christi [email protected] http://sci.tamucc.edu/~magesh August 15, 2013 Presented to AgriLife Leadership Development
Transcript of Academy Speaks Again - Texas A&M...
Academy Speaks Again
‘Plasmas & Possibilities’
Dr. Magesh Thiyagarajan Director of Plasma Engineering Research (PERL)
Assistant Professor of Engineering School of Engineering & Computing Sciences
College of Science and Engineering Texas A&M University – Corpus Christi
[email protected] http://sci.tamucc.edu/~magesh
August 15, 2013
Presented to AgriLife Leadership Development
Natural and Man-made Plasmas
Welding Cutting Lighting
Rocket
Propulsion
Space
Research Fusion
Microprocessor and
Semiconductor Processing
Medical Military and Air force Biomedical Applications
Plasmas & Cold Plasmas
Ionization creates free radicals & reactive oxygen species which are biologically active, making plasma very effective in sterilization and wound healing.
Plasma is created when a gas, including air, passes through an electromagnetic field. The gas becomes ionized and the free electrons make the plasma very energetic, accelerating the ionization process.
Cold Plasma: Ionizing the gas without heating the gas using advanced electromagnetic excitations.
Plasma Engineering Research Program
PERL: Interdisciplinary Research
• Mechanical, Electrical, Chemical Engineering
Engineering
• Laser induced high density plasmas
Physics
• Plasma processing- surface modifications
Chemistry
• Cold plasma bacterial inactivation
Microbiology
• Cold plasma cancer treatment
Biomedical Science
Post-doc, Scientists,
Faculty
Grad
UG
Laser induced plasmas and shockwave interactions
Research Applications: ◦ nuclear fusion, nuclear fission,
material characterization, pulsed power and space applications
Collaboration: ◦ Sandia National Lab
◦ TAMU
Laser induced high density plasmas
Recent Publication: ◦Thiyagarajan et. al. , JOURNAL OF APPLIED PHYSICS, v.111, 7, 2012.
◦Thiyagarajan et. al. , IEEE Transactions on Plasma Science, 2012.
Configurable Cold Plasma Sources
1 slm 2 slm 3 slm 4 slm 5 slm6 slm 7 slm
Cold Plasma Atmospheric Pressure
Large Volume Configurable
Materials Processing
• Increase Surface Energy • Modify Material Surface wettability and adhesive properties • Improve the surface properties of bio-polymers • Biomedical applications
Bacterial decontamination
Escherichia coli
Staphylococcus aureus (MRSA)
Neisseria meningitidis
Pseudomonas aeruginosa
Bacillus
Salmonella
Vibrio Vulnificus
Solid Surfaces
Dry/Moist Surfaces
Liquids (water)
• Sterilization of Medical and Surgical Instruments • Hospitals (Hospital Acquired Infections) and other public places • Water decontamination
Is our Food Safe to eat?
Recognizing Foodborne Illnesses Can’t rely on seeing, smelling or tasting bacteria in food
48 Million people get sick every year!!
Bacillus cereus Undercooked Foods Food poisoning
Escherichia coli Poorly prepared meats & produce Food poisoning
Salmonella Meat, poultry, dairy Enteric fever
Staphylococcus aureus (MRSA) Ham, poultry, potato salad, sauces… Meningitis, Osteomyelitis, Toxic Shock…
Vibrio (>80 species) Undercooked fish, shellfish Gastroenteritis, Cholera, Septicemia
Most Common Food-borne Pathogens
Frequently Recalled Foods: Poultry and Produce
Cold Plasma for Food Safety!
Food Industry requires 3-Log Reduction of pathogens
100 99.99%
10 99.999%
1 99.9999%
Industry Standard
Plasma Sterilization can achieve up to a 5-6 Log reduction in pathogen loading
Bacillus cereus
E. coli
Salmonella
(MRSA)
Vibrio (>80 species) Undercooked fish, shellfish Gastroenteritis, Cholera, Septicemia
Cold Plasma for Food Sterilization
Cold Plasmas for Cancer Treatment
• Magesh Thiyagarajan, Abdollah Sarani, and Xavier Gonzales. "Characterization of Portable Resistive Barrier Plasma Jet and Its Direct and Indirect Treatment for Antibiotic Resistant Bacteria and THP-1 Leukemia Cancer Cells." IEEE Transactions on Plasma Science - Special Issue on Atmospheric Pressure Plasma Jets. 40, no. 12 (2012): 3533 – 3545
Cold Plasma Cancer Treatment Research
Viability Studies Staining Cancer Cells Apoptosis vs Necrosis
Fluorescent Microscopy Flow-cytometry Studies Cell Death Pathways
Cancer: On the Run Cold Plasmas!
U.S. Department of Defense
U.S. Army
Telemedicine & Advanced Technology Research Center
(TATRC)
Texas Research and Development Funds
Texas Higher Education Funds
College of Science and Engineering
School of Engineering & Computing Sciences
Texas A&M University- Corpus Christi
NSF-TAMUCC Louis Stokes Alliances for Minority
Participation (LSAMP) Program
TAMUCC McNair Scholars Program
Grant Funded Research Sponsors
The PERL Group Says…
At PERL We Say….
Plasmas: Possibilities are Endless!!!
Thank you!
