What do these words mean?. 2 Organic Compounds CompoundsCARBON organicCompounds that contain CARBON...
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Transcript of What do these words mean?. 2 Organic Compounds CompoundsCARBON organicCompounds that contain CARBON...
What do these words mean?
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Organic CompoundsOrganic Compounds
• CompoundsCompounds that contain CARBONCARBON are called organicorganic.
• MacromoleculesMacromolecules are large organic moleculesorganic molecules.
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Carbon (C)Carbon (C)• CarbonCarbon has 4 electrons4 electrons in
outer shell.
• CarbonCarbon can form covalent covalent bondsbonds with as many as 4 4 other atoms (elements).
• Usually with C, H, O or NC, H, O or N.
• Example: CH4 (Methane)Example: CH4 (Methane)copyright cmassengale
Next Word…..
Polygons
Polygamy
Polyester
What does “Mono” mean?
A PolymerA PolymerHere are some analogies to better
understand what polymers and monomers are….
EXAMPLE of POLYMER
MONOMER
A TRAIN ?
A NECKLACE ?
If the train is the whole polymer, what would be If the train is the whole polymer, what would be the small groups that make up the train? If the the small groups that make up the train? If the necklace is the polymer, what are the monomers necklace is the polymer, what are the monomers that make up the necklace?that make up the necklace?
A PolymerA PolymerHere are some analogies to better
understand what polymers and monomers are….
EXAMPLE of POLYMER
MONOMER
A TRAIN THE CARS
A NECKLACE EACH PEARL
If the train is the whole polymer, what would be If the train is the whole polymer, what would be the small groups that make up the train? If the the small groups that make up the train? If the necklace is the polymer, what are the monomers necklace is the polymer, what are the monomers that make up the necklace?that make up the necklace?
Now you and a buddy
need to think of at least 2 other analogies for a polymer and its
monomers.
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Question:Question:How Are How Are
Macromolecules Macromolecules Formed?Formed?
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Answer:Answer: Dehydration Synthesis Dehydration Synthesis
• Also called “condensation “condensation reaction”reaction”
• Forms polymerspolymers by combining monomersmonomers by “removing “removing water”water”.
HO H
HO HO HH
H2O
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Question:Question: How are How are
Macromolecules Macromolecules separated or separated or
digested?digested?
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Answer: Answer: HydrolysisHydrolysis
•Separates monomersmonomers by “adding water”“adding water”
HO HO HH
HO H
H2O
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Look at the label to the left. 3 of the 4 macromolecules can
be found in foods. The 3 biochemical molecules
found on a nutrition label are:
1____________________
2____________________
3____________________
(0 grams in this product)
(13 grams in this product)
(9 grams in this product)
LET’S BEGIN WITH CARBOHYDRATES
They are the main source for the body to gain energy. They are our fuel!
They make up the cell wall in plants which allow them to grow tall, without this carbohydrate, a plant would be a mushy mess! This type of carbohydrate is called Cellulose.
THINK: CARBS= ENERGY and CELL WALLS
CARBOHYDRATES
Each carbohydrate is made up Each carbohydrate is made up of…of…
THINK: “CHO”THINK: “CHO”
CARBOHYDRATES
THERE ARE 2 TYPES OF THERE ARE 2 TYPES OF CARBOHYDRATESCARBOHYDRATES
SimpleSimple ComplexComplex
Simple Sugars are carbohydrates made up of 1 or 2 monomers.
They also taste sweet.
CARBOHYDRATES
Carbohydrates are chains Carbohydrates are chains (polymers) made of (polymers) made of
monomers. The most common monomers. The most common monomer of carbohydrates monomer of carbohydrates
is…is…
The shape of Glucose is a hexagonal ring
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CarbohydratesCarbohydratesMonosaccharide: one sugar Monosaccharide: one sugar
unitunit
Examples:Examples: glucose (glucose (C6H12O6)
deoxyribosedeoxyribose
riboseribose
FructoseFructose
GalactoseGalactose
glucoseglucose
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Simple Sugars
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CarbohydratesCarbohydrates
Disaccharide: two sugar unitDisaccharide: two sugar unit
Examples: Examples: – Sucrose (glucose+fructose)Sucrose (glucose+fructose)– Lactose (glucose+galactose)Lactose (glucose+galactose)– Maltose (glucose+glucose)Maltose (glucose+glucose)
glucoseglucoseglucoseglucosecopyright cmassengale
Complex Carbohydrates…What are they?
Complex Cabohydrates are polymers Complex Cabohydrates are polymers made up of many monomers.made up of many monomers.
Most also taste starchy.Most also taste starchy.
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CarbohydratesCarbohydratesPolysaccharide: many sugar unitsPolysaccharide: many sugar units
Examples:Examples: starch (bread, starch (bread, potatoes)potatoes)
glycogen (beef glycogen (beef muscle)muscle)
cellulose (lettuce, cellulose (lettuce, corn)corn)
glucoseglucoseglucoseglucose
glucoseglucoseglucoseglucose
glucoseglucoseglucoseglucose
glucoseglucoseglucoseglucose
cellulosecellulose
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Complex Carbohydrates
NOW ONTO PROTEINS
They are the major structural molecules in living things for growth and repair : muscles, ligaments, tendons, bones, hair, skin, nails…IN FACT ALL CELL MEMBRANES have protein in them
They make up antibodies in the immune system
They make up enzymes for helping chemical reactions
They makeup non-steriod hormones which
THINK: Proteins= membranes, enzymes, antibodies, non-steriod hormones, structural molecules, “MEANS”
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Proteins (Polypeptides)Proteins (Polypeptides)• Amino acids (20 different kinds of aa) bonded
together by peptide bondspeptide bonds (polypeptidespolypeptides).
• Six functions of proteins:Six functions of proteins:1.1. Storage:Storage: albumin (egg white)albumin (egg white)2.2. Transport: Transport: hemoglobinhemoglobin3.3. Regulatory:Regulatory: hormoneshormones4.4. Movement:Movement: musclesmuscles5.5. Structural:Structural: membranes, hair, nailsmembranes, hair, nails6.6. Enzymes:Enzymes: cellular reactionscellular reactions
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Microscope View ofSkin and Nails
This is skin This is a nail
PROTEINS
Proteins are made of long Proteins are made of long chains (polymers) made of chains (polymers) made of monomers. All proteins are monomers. All proteins are
made of the monomer…made of the monomer…
http://www.hcc.mnscu.edu/programs/dept/chem/V.27/amino_acid_structure_2.jpg
http://upload.wikimedia.org/wikipedia/commons/thumb/c/c5/Amino_acids_2.png/483px-Amino_acids_2.png
PROTEINS
Each protein is made up of…Each protein is made up of…
THINK: “CHONS”THINK: “CHONS”
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Proteins (Polypeptides)Proteins (Polypeptides)
Four levels of protein Four levels of protein structure:structure:
A.A. Primary StructurePrimary Structure
B.B. Secondary Structure Secondary Structure
C.C. Tertiary Structure Tertiary Structure
D.D. Quaternary Structure Quaternary Structure
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Primary StructureAmino acids bonded
together by peptide peptide bonds (straight chains)bonds (straight chains)
aa1 aa2 aa3 aa4 aa5 aa6
Peptide Bonds
Amino Acids (aa)
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Secondary StructureSecondary Structure
• 3-dimensional folding arrangement of a primary primary structurestructure into coilscoils and pleatspleats held together by hydrogen bondshydrogen bonds.
• Two examples:Two examples:
Alpha HelixAlpha Helix
Beta Pleated SheetBeta Pleated Sheet
Hydrogen BondsHydrogen Bondscopyright cmassengale
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Tertiary StructureTertiary Structure• Secondary structuresSecondary structures bentbent and
foldedfolded into a more complex 3-D more complex 3-D arrangementarrangement of linked polypeptides
• Bonds: H-bonds, ionic, disulfide Bonds: H-bonds, ionic, disulfide bridges (S-S)bridges (S-S)
• Call a “subunit”.“subunit”.
Alpha HelixAlpha Helix
Beta Pleated SheetBeta Pleated Sheetcopyright cmassengale
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Quaternary StructureQuaternary Structure•Composed of 2 or more “subunits”•Globular in shape•Form in Aqueous environments•Example: enzymes (hemoglobin)enzymes (hemoglobin)
subunitssubunits
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LIPIDS ARE NEXT
They are a great source of STORED ENERGY so we have it in the future.
They INSULATE the body to maintain normal body temperature and they CUSHION the internal organs for protection.
They produce hormones for the body called STERIODS
They waterproof surfaces of animals,plants, and fruits- these are waxes!
THINK: Waterproof, insulate, steriods, energy, cushion… “WISE C”
LIPIDS
Each carbohydrate is made up Each carbohydrate is made up of…of…
THINK: “CHO”THINK: “CHO”
OH NO CHO! Lipids like Carbs?
You might have noticed that both carbohydrates and lipids have the elements Carbon, Hydrogen, and Oxygen.
“CHO”
A carbohydrate, has twice as many hydrogen atoms as the number of oxygen atoms.
EX: C6H12O6
(This is a carb= there are double the number of H compared to O)
On the other hand, lipids have a lot more than twice the amount hydrogen atoms as the number of oxygen atoms.
EX: C27H46O cholesterol
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LipidsLipids• General term for compounds which are not not
soluble in watersoluble in water.• Lipids are soluble in hydrophobic solventsare soluble in hydrophobic solvents.• Remember:Remember: “stores the most energy”“stores the most energy”• Examples:Examples: 1. Fats1. Fats
2. Phospholipids2. Phospholipids3. Oils3. Oils4. Waxes4. Waxes5. Steroid hormones5. Steroid hormones6. Triglycerides6. Triglycerides
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LipidsLipidsSix functions of lipids:Six functions of lipids:
1.1. Long term Long term energy storageenergy storage2.2. Protection against heat loss Protection against heat loss (insulation)(insulation)3.3. Protection against physical shockProtection against physical shock4.4. Protection against water lossProtection against water loss5.5. Chemical messengers (hormones)Chemical messengers (hormones)6.6. Major component of membranes Major component of membranes (phospholipids)(phospholipids)
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LIPIDS
Lipids are chains (polymers) Lipids are chains (polymers) made of monomers. The most made of monomers. The most
common monomer of lipids common monomer of lipids is…is…
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LipidsLipidsTriglycerides:Triglycerides:
ccomposed of 1 glycerol1 glycerol and 3 3 fatty acidsfatty acids.
H
H-C----O
H-C----O
H-C----O
H
glycerol
O
C-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH3
=
fatty acids
O
C-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH3
=
O
C-CH2-CH2-CH2-CH =CH-CH2 -CH
2 -CH2-CH
2-CH3
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The Shape of a triglyceride is like the letter E
This is a triglyceride molecule
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Fatty AcidsFatty AcidsThere are two kinds of fatty acidsfatty acids you may see these on
food labels:
1.1. Saturated fatty acids:Saturated fatty acids: no double bonds (bad) no double bonds (bad)
2.2. Unsaturated fatty acids:Unsaturated fatty acids: double bonds (good) double bonds (good)O
C-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH3
=
saturatedsaturated
O
C-CH2-CH2-CH2-CH=CH-CH2-CH
2-CH2 -CH
2 -CH3
=unsaturated
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Saturated Fatty Acids have no double bonds and are saturated with hydrogen.
Unsaturated Fatty Acids have double bonds.
www.agen.ufl.edu/~chyn/age2062/lect/lect_02/3_16.gif
Cis and Trans Fatty Acids
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/cis_trans.gif
Cis –vs-Trans Shapes
http://www.mansfield.ohio-state.edu/~sabedon/047cis.gif
LIPIDS…Some interesting info
There are many different types of There are many different types of steroids. They are all lipids. Their steroids. They are all lipids. Their functions vary. Some common functions vary. Some common steroids are:steroids are:
SEX STEROIDSSEX STEROIDS ANABOLIC ANABOLIC STERIODSSTERIODS
CHOLESTEROLCHOLESTEROLLike testosterone Like testosterone and estrogenand estrogen
They increase They increase musclemuscle
LIPIPS…Some interesting info
Some anabolic Some anabolic steroids are steroids are illegalillegal
And can be dangerous and
very unhealthy
NATURAL STERIODS IN OUR NATURAL STERIODS IN OUR BODY INCREASE MUSCLE BODY INCREASE MUSCLE
GROWTH AND BONE GROWTH AND BONE DEVELOPMENT AND ARE DEVELOPMENT AND ARE
GOOD. THE ILLEGAL ONES GOOD. THE ILLEGAL ONES THAT ARE SYNTHETIC ARE THAT ARE SYNTHETIC ARE
BAD.BAD.
NUCLEIC ACIDS
THERE ARE 2 TYPES OF THERE ARE 2 TYPES OF NUCLEIC ACIDSNUCLEIC ACIDS
DNADNA RNARNA
Nucleic Acids
1) DNA• Is our genetic material. Chromosomes are
made of DNA.• Chromosomes contain the “recipes” to make
proteins for your body.
2) RNA• Reads the DNA “protein recipes” and makes
the proteins for your body.
Nucleic Acids
Each nucleic acid is made up Each nucleic acid is made up of…of…
THINK: “PONCH”THINK: “PONCH”
NUCLEIC ACIDS
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Nucleic acidsNucleic acids
• Two types:Two types:a. Deoxyribonucleic acid a. Deoxyribonucleic acid
(DNA-(DNA- double helix) double helix) b. Ribonucleic acid (RNA-single b. Ribonucleic acid (RNA-single strand) strand)
• Nucleic acids Nucleic acids are composed of long chains of nucleotidesnucleotides linked by dehydration synthesisdehydration synthesis.
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Nucleic acidsNucleic acids• Nucleotides include:Nucleotides include:
phosphate groupphosphate grouppentose sugar (5-carbon)pentose sugar (5-carbon)nitrogenous bases:nitrogenous bases:
adenine (A)adenine (A)thymine (T) DNA onlythymine (T) DNA onlyuracil (U) RNA onlyuracil (U) RNA onlycytosine (C)cytosine (C)
Guanine (G)Guanine (G)
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NucleotideNucleotide
O
O=P-O O
PhosphatePhosphate GroupGroup
N
Nitrogenous baseNitrogenous base (A, G, C, or T)(A, G, C, or T)
CH2
O
C1C4
C3 C2
5
SugarSugar(deoxyribose)(deoxyribose)
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DNA - double helixDNA - double helix
P
P
P
O
O
O
1
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4
5
5
3
3
5
P
P
PO
O
O
1
2 3
4
5
5
3
5
3
G C
T A
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The shape of a nucleic acid is:
ENERGY
Energy that is gained by Energy that is gained by consuming food is called a consuming food is called a
ENERGY
Three of the BIG 4 provide Three of the BIG 4 provide us with energy through the us with energy through the food we eat:food we eat:BIG 4
MACROMOLECULES
Number of Calories it provides
Carbohydrates
Proteins
Lipids
Nucleic Acids
ENERGY So…So…
BIG 4 MACROMOLECULES
Number of Calories it provides
Carbohydrates 4
Proteins 4
Lipids 9
Nucleic Acids 0
TEST: TEST: Are you smart? If you eat a sandwhich with 46 grams of carbs and 24 grams of protein and 10 grams of fat, how much energy
will you gain?
Which one of the following molecules is a lipid?
A carbohydrate?
1.) C27H46O
2.) C12H24O12
LipidLipid
CarbohydrateCarbohydrate
• What kind of carbohydrate gives you a quick burst of energy? • What kind of carbohydrate gives you long term energy? • You are stranded on a desert island and have found a box of
food. Considering you have almost nothing to eat on the island, which of the following would be the best food to have in the box? WHY?– Crackers– Butter– Steak
• How many Calories are found in 1 gram of protein?
• How many Calories are in 1 gram of nucleic acid?
Final Review QuestionsPlease do not look back at the information in your handout until you
have answered all of the following questions.
1. What are 2 examples of simple sugars and 2 examples of complex carbohydrates not mentioned already?
2. What is a polymer?
3. What is a monomer?
4. Carbohydrates are the body’s main source of ________________.
5. Define in your own words:
Biochemical
Macromolecule
6. Proteins are major structural molecules in living things. List 5 places or things in your body that contain a lot of protein.
7. What are enzymes? What are they made of?
8. What are hormones?
9. What does your thyroid hormone do?
10. Name three types of proteins.
11. What are the functions of lipids?
12. What elements are found in each of the Big 4 molecules?
13. What does DNA do? RNA?
14. How many Calories are found in 1 gram of each of the Big 4 molecules?
15. What are 5 possible effects of illegal steroid use?
16. What are 3 functions of lipids?
17. What is the function of waxes?
18. What are 2 ways simple sugars are different from complex carbohydrates?
19. What are 4 organic macromolecules?