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Educational Resources

Center for Translational Science Activities

WelcomeCertificate Program Orientation

April 30, 2013

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Agenda

• Introductions

• CTSA Program Overview

• Certificate Requirements

• Research Proposal

• Scholar/Mentor Relationships

• Competencies

• Program Evaluations & Outcomes

• Questions

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CPXXXXXX-1

CTSA Executive Committee

Robert A. Rizza, MDMayo Clinic Director for Research

CTSA Director and Principal Investigator

David O. Warner, MDMayo Clinic Associate Director for Clinical/Translational Research

CTSA Associate Director and Co-PI

Scott Kaese / Jane C. WelterAdministrators, Mayo Clinic Research Administrative Services

CTSA Director / Associate Director of Administration

ResearchResourcesS. Khosla, MD

Co-PI and Director

Education Resources

D. Warner, MDCo-PI and Director

External AdvisoryCommittee

Internal AdvisoryCommittee

CTSA Academic AffairsCommittee

CommunityEngagement

P. Targonski, MD PhDCo-PI and Director

03/27/13

Pilot andFeasibility

Research ResourcesReview Panel (RRRP)

ScientificReview Panels

NovelMethodology

Community-Based Research

Networks

Translating Comparative Effectiveness Research into

Practice (TRACER)

Office for Community

EngagedResearch(OCER)

ResearchVolunteer

Resource (RVR)

PredoctoralPrograms

PostdoctoralPrograms

Research Management

Programs

ClinicalResearch

Unit (CRU)

Saint MarysCharltonMobile

MedicalStudent

Programs

CTS Masters and Certificate

ProgramsTranslationalTechnologyCores (TTC)PhD & MD/PhD

Program in CTSKL2 Mentored Career Devel

Program

Scholarly OpportunityAward

RegulatorySupport

Research Ethics

Resource

Consultative, Regulatory, and

Informatics Services

R. D. Simari, MDCo-PI and Director

Communications

Continuous Professional Development

Program

Study Coordinator

Degreeand Diploma

Programs

SpecializedPhenotyping

Facilities

Study Design and

Biostatistics

BiomedicalInformatics

Res. SubjectAdvocacyServices

Research Information

Center

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Mayo ClinicCenter for Translational Science Activities (CTSA)

• CTSA Research Resources (CRU)

• CTSA Community Engagement

• CTSA Consultative, Regulatory and Informatics Services

• CTSA Education Resources –

David O. Warner, MD, Director

Glenn E. Smith, PhD, LP, Associate Director

• CTSA Certificate Program –

W. Ray Kim, MD, Director

Shawna L. Ehlers, PhD, LP, Associate Director

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CTSA Postdoctoral Program

Goal:

To train clinicians to participate in intramurally- and extramurally-funded patient-based research.

The Social Contract of Medical Research (discovering and applying knowledge to improve health) is a privilege.

AAMC-GREAT Group

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Certificate Program Expectations

• Find time for coursework: • 1 hr. lecture = 2-4 hours outside work• 1 credit = 48 hours/qtr or 4 hours/week• 3 cr/qtr ~ 12 hours/week• Aligned with research goals

• Accept feedback from mentors/tutors/peers

• Learn to identify the important questions

• Take charge of your destiny

• Submit by deadlines indicated

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Certificate Program Requirements

• 12 didactic credits• 7 required• 5 electives

• “Writing for Biomedical Publications” workshop

• Research resulting in publication

• Manuscript & Mentor Summary Letter & CV

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CourseworkRequired Courses:

• CTSC 5300 & 5310 Clinical Epidemiology I & II (1 cr each)

• CTSC 5600 Statistics in Clinical Research (2 cr)

• CTSC 5010 Clinical Research Protocol Development (2 cr)

• CORE 6000 Responsible Conduct of Research (1 cr)

Courses available in-person and online

Registration begins one month prior to each quarter

• Required: 7 credits begining either summer or winter quarter

• Electives: 5 credits of either CTSC or MGS courses

• Up to 3 graduate credits may be transferred – must relate to your project

• Mayo Graduate School Course Information

• CTSA Annual Course Schedule

• Publication Workshop: March 6, 2014

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Potential Elective Courses• CTSC 5640 Logistic Regression

• CTSC 5650 Survival Analysis

• CTSC 5720 Clinical Trials: Design & Conduct

• MPET 6820 Regenerative Medicine

• CTSC 5080 Eliminating Health Disparities

• CTSC 5810 Qualitative Research Design

• CTSC 5860 Behavioral Interventions in Clinic Research

• CTSC 5870 Social & Behavioral Foundations of Health in HSR

• BMB 8350 Intro to Bioinformatics

• CTSC 5140 Epigenetics and Epigenomics

• CTSC 5660 Design analysis & App of Bioinformatics

• CTSC 5960 Medical Informatics

• CTSC 5760 Medical Decision Making

• CTSC 5761 Evidence Based Medicine for Clinical Researchers

• CTSC 5910 Economic Evaluation in Health Care

• CTSC 5940 Secondary Data Analysis

Clinical Trials

Behavioral

Individualized Medicine

Healthcare Delivery

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Workshops

Required Workshop:• Writing for Biomedical Publications

• March 6, 2014 ~ offered once per year only• Available at all three sites (MCR, MCA, MCF)• Registration Fee - $275 (fee waived)

Optional Workshop:• Write Winning Grants

• November 8, 2013 ~ offered once per year only• Available at all three sites (MCR, MCA, MCF)• Registration Fee - $275 (fee waived)

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Research Proposal Packet• Utilize CTSC 5010 Clinical Research Protocol Development

• If you take course in the fall, submit proposal in January• If you take course in the spring, submit proposal in July

• Research Proposal Format

• Reviewed using the Research Proposal Review Criteria

• Includes:• Cover page• Cover letter signed by you and your mentor• Research proposal• Division research committee approval• IRB approval

• Submission cycle to CTSA approval is twice each year• January or July only• Early submissions are accepted

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Program Timeline

• Research Proposal Packet – Due January 2, 2014• Writing Workshop – March 6, 2014• Progress Report – April 1, 2014• Coursework complete (3.0 GPA) – June, 2014• Manuscript & Mentor Summary Letter – June, 2014

• Cite the Grant!

• Reviewed by Postdoctoral Committee

If requirements have been fulfilled – Certificate is awarded!

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Scholar and Mentor Relationships

ExpectationsThese are meant as a guide to help facilitate optimal scholar/mentor relationships. Contact CTSA if issues arise.

1) Initial Agreement – at time of application2) Progress Report – submitted 2 months

after research proposal is approved3) Mentoring Effectiveness Assessment

(Scholar & Mentor) – will be requested annually, spring quarter.

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Competencies• Critically evaluate clinical/translational research in the

medical literature

• Articulate the ethical & legal responsibilities of an investigator

• Develop feasible and testable hypotheses

• Design and conduct a clinical/translational research project

• Write competitive grant proposals

• Effectively communicate research results through publication

• Effectively communicate research results through presentation

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Competencies (cont.)

• Articulate and apply appropriate study designs

• Use appropriate biostatistical methods

• Understand the peer-review process

• Ability to navigate the peer-review process for grants and papers

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Program Evaluations & Outcomes

Program Evaluation Activities• Clinical Translational Research Appraisal

(CTRAI) Pre/Post self-assessment – completed in CTSC 5300 Epi I and at end of program

• Mentor Assessments – annual• Course Evaluations• Graduate tracking – annual CVs

Publications, grants, promotions, awards, patents, leadership and professional activities, etc.

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Websites to know

CTSA Education Resourceshttp://ctsa.mayo.edu/education/index.html

• Quarterly Course Schedule• Program Milestones• New course listings• This presentation

Mayo Graduate School http://mayoweb.mayo.edu/mgs/

• Quarterly course listing• Course Registration • Other required forms

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“The research we do today will determine

the type of medical and surgical practice

we carry on at the Clinic tomorrow.”

-William J. Mayo, M.D.

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QUESTIONS