Treatment Options for your Knee Pain

HOW YOUR KNEE WORKS

Anatomy of the knee• Largest joint in body

• Referred to as a hinge joint because it allows the knee to flex & extend; while hinges can only bend and straighten, the knee has the ability to rotate (turn) & translate (glide)

• 3 bones

• Shin bone (tibia)

• Thigh bone (femur)

• Kneecap (patella)

WHAT’S CAUSING YOUR PAIN?

It’s estimated 70 million people in the U.S. have some form of arthritis.1 Osteoarthritis is one of the most common types. •Osteoarthritis

• Wear and tear that deteriorates the “cushion” in your joints

• A degenerative condition—it won’t get better and may get worse

•Rheumatoid arthritis

• An autoimmune disease that attacks the lining of joints, causing swelling, possibly throbbing painand deformity

1. Landers, S. Another reason to exercise for those with arthritis. American Medical Association website. <http://www.ama-assn.org/amednews/2005/05/02/hlsc0502.htm>, 2005.

WHAT’S CAUSING YOUR PAIN?

Healthy knee The end of each bone in the joint is covered with cartilage, acting as a cushion so the joint functions without pain

Diseased knee (osteoarthritis) Wear and tear deteriorates natural cushion, leading to bone-on-bone contact, soreness and swelling

ASSESSING YOUR PAIN

• Does your knee hurt one or more days per week?

• Does the pain interfere with your sleep?

• Is it painful for you to walk more than a block?

• Are pain medications no longer working?

• Is knee pain limiting your participation in activities(e.g. family vacations or other functions)?

• Has inactivity from knee pain caused you to gain weight?

Little or no pain

Excruciating, debilitating pain

ASSESSING YOUR PAIN

• Rate your pain on a scale of 1 to 5

• For most people, the tipping point is about 4 or 5— that’s when the pain becomes too difficult and they turn to a surgeon for relief1

1. 2007 DePuy Orthopaedics, Inc. Knee Attitudes & Usage Study.

ASSESSING YOUR PAIN

Check your mobility

If you have difficulty performing any of the movements below, it may be time to talk to your doctor about next steps

Walk Bend at thehips and knees

Pretend to drive: push the gas/brake

Pretend to golf: swing a club

HOW CAN YOUR PAIN BE TREATED?

Water therapy• Soaking, ice packs, hot packs

Exercise & physical therapy• Also good for weight loss

Medications• Analgesics• Corticosteroids

Injections• Corticosteroids, hyaluronic acid

(e.g., ORTHOVISC®)

ORTHOVISC® is a trademark of Anika Research, Inc.

KNEE REPLACEMENT

• Implants replace damaged surfaces

• Helps relieve pain and restore mobility

•In 2011, more than 650,000 total knee replacements were performed in the United States1

•One study has shown that ten years after surgery, 99.6% of patients still depend on their SIGMA® Knees with fixed bearing option in their daily lives2

1. 2012 Premier, Inc.2. Dalury et al. Midterm results with the P.F.C. SIGMA Total Knee Arthroplasty System. The Journal of Arthroplasty

Vol.23, No.2, 2008: 175-181.

Femoral component

Tibial component

WHAT IS KNEE REPLACEMENT?

A surgical procedure that removes and replaces diseased joint surfaces with implants

Femoral component

Tibial component

Patellar component

Polyethylene insert

HOW DOES IT WORK?

• Diseased areas at top of shin bone (tibia) and bottom of thigh bone (femur) are removed and reshaped

• Femoral component covers the thigh bone (femur)

• Tibial component covers the shin bone (tibia)

• Polyethylene insert placed between femoral and tibial components

• Patellar component replaces the kneecap (patella)

Healthy knee Knee replacement

HOW DOES IT WORK?

DEPUY SYNTHES JOINT RECONSTRUCTION

SIGMA® KNEES

• SIGMA Knees come in a wide range of shapes, sizes and materials

• Your surgeon may be able to fit you with a SIGMA Knee designed to provide a natural feel and movement

• The SIGMA Knee is an example of a proven design that continues to evolve to meet the demands of today’s patients

FIXED BEARING KNEES

• Most widely used type of knee replacement in the U.S. today1

• Designed to enhance stability of the joint

• New designs and advanced materials - Helps reduce wear

1. IMS Health

SIGMA® FIXED BEARING KNEES

SIGMA® ROTATING PLATFORM KNEES

Designed to rotate as it bends, imitating your natural knee movement

•The surfaces of the knee joint roll and glide against each other as you bend. In other words, your knee naturally rotates as it bends

•Designed for patients who want to remain active since it minimizes implant wear, compared to traditional knee replacements1

•One study has shown after 20 years, 97% of patients still depend on their rotating platform knees in their daily lives2

1. McNulty, D. et al. “In Vitro Wear Rates of Fixed-bearing and Rotating Platform Knees (Rev. 2).” 2003.2. Buechel F., et al. “Twenty Year Evaluation of Meniscal Bearing and Rotating Platform Knee Replacements.” Clinical Orthopaedics and Related Research July 2001: 41-50..

SHOULD YOU WAIT TO REPLACE YOUR KNEE?

Assess your pain and ability to function• Do you feel severe pain in your knee?• Has the pain and loss of function affected your quality of life?• Do you have difficulty sleeping or performing basic functions

(walking, driving, climbing stairs)? • Does medication no longer provide relief?

Consult your physician

Early diagnosis and treatment are important1

• Delaying may lower your quality of life2

Osteoarthritis is degenerative—it won’t get better and may get worse

1. Fortin PR, et al. Outcomes of Total Hip and Knee Replacement. Arthritis & Rheumatism. 1999;42:1722-1728. 2. Fortin PR, et al. Timing of Total Joint Replacement Affects Clinical Outcomes Among Patients With

Osteoarthritis of the Hip or Knee. Arthritis & Rheumatism. 2002;46:3327-3330.

IMPORTANT SAFETY INFORMATION

• As with any medical treatment, individual results may vary

• The performance of joint replacements depends on your age, weight, activity level and other factors

• There are potential risks, and recovery takes time

• People with conditions limiting rehabilitation should not have this surgery

• Only an orthopaedic surgeon can tell if knee replacement is right for you

SUMMARY

• The leading cause of knee pain is osteoarthritis

• Osteoarthritis is degenerative – it won’t get better and may get worse

• Early diagnosis and treatment for total knee replacement are important1

• An Arthritis Foundation® study shows knee replacement has a 90-95% rate of patient satisfaction2

• SIGMA Knees come in a wide range of shapes, sizes and materials, so your surgeon can recommend the implant that is right for you.

Arthritis Foundation® is a trademark of The Arthritis Foundation, Inc.

1. Fortin, Paul R., et al. Outcomes of Total Hip and Knee Replacement. Arthritis & Rheumatism 42 (1999): 1722-17282. The Arthritis Foundation. <http://arthitis.org/research/Bulletin/vol5no11/Printable.htm>, 2006.

QUESTIONS?

THANK YOU!

© DePuy Synthes Joint Reconstruction, a division of DOI 2013

ADDITIONAL SLIDES

The following slide is the SIGMA® High Performance Partial Knees module.

If desired, please select the appropriate slides to include within this

presentation.

REMOVE THIS SLIDE WHEN PRESENTING

SIGMA® HIGH PERFORMANCE PARTIAL KNEES

High Performance Partial Knees

Can replace any of the three areas of your knee; replacing only the damaged area maintains more of your natural knee

•May be an option for more active patients who require a high degreeof flexion but not total knee replacement

•Accommodates deep knee flexion, the movement needed for kneeling,squatting or sitting cross-legged

•Less invasive with potential for faster recovery than total knee replacement

ADDITIONAL SLIDES

The following 3 slides are the TRUMATCH® Personalized Solutions

module.If desired, please select the appropriate

slides to include within this presentation.

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TRUMATCH® PERSONALIZED SOLUTIONS

What is TRUMATCH?

• Uses advancements in technology to provide surgeons with customized surgical guides that are designed specifically for your knee anatomy

BENEFITS OF TRUMATCH SOLUTIONS

• Helps your surgeon achieve consistency in the placement and positioning of your knee replacement

• TRUMATCH instruments help your surgeon to obtain a precise fit of the implant. The implant helps reduce a patient’s pain and restore their mobility

• Reduces number of surgical steps

TRUMATCH® PERSONALIZED SOLUTIONS

How does it work?

• A CT scan of your leg is taken

• A 3-D model of your knee is developed

• Personalized guides are created based on your unique anatomy

• Your guides help your surgeon position and place your new knee implant

• Guides are removed by your surgeon prior to your new knee being implanted

ADDITIONAL SLIDES

The following 3 slides are the SIGMA®

Partial Knee Alternative module.If desired, please select the appropriate slides to include within this presentation.

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THE PARTIAL KNEE ALTERNATIVE

“Partial”

“Total”

PARTIAL KNEE REPLACEMENT

Removes only the damaged area of the knee

Uses metal and plastic implants to replace the damaged area, helping to relieve pain and restore natural movement.

POTENTIAL ADVANTAGES OF A PARTIAL KNEE

• Maintains more of the healthy ligaments and bone, helping to restore the natural movement during activities

• Potential for faster recovery

• Minimally invasive procedure to reduce blood loss

• Possible reduced scarring

Unicondylar Patellofemoral

ADDITIONAL SLIDES

The following 3 slides are thegender-specific module.

If desired, please select the appropriate slides to include within this presentation.

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IMPORTANT CONSIDERATIONS FOR WOMEN

• Osteoarthritis affects three times more women than men1

− Women are more likely than men to be disabled− The pain is more severe for women2

• Current knee replacements are designed to fit the anatomies of both women and men

1. Hawker, Gillian A., et al. "Differences Between Men and Women in the Rate of Use of Hip and Knee Arthroplasty.“The New England Journal of Medicine 342 (2000): 1016-1022

2. Harris Interactive research survey, April 2005

GENDER-SPECIFIC IMPLANTS

• All orthopaedic manufacturers have knee implant systems with sizes appropriate for both female and male patients

− Surgeons know which knee will fit each patient best, based on gender, age, size, activity levels and aspirations

GENDER-SPECIFIC IMPLANTS

• More than 60% of knee replacements have been implanted in women1

• Current knee replacement patients have a 90 to 95% satisfaction rate with the results of their surgery2

1. American Academy of Orthopaedic Surgeons<http://www.aaos.org/wordhtml/research/stats/Hipkneefacts.htm>, 2006.

2. The Arthritis Foundation<http://www.arthritis.org/research/Bulletin/vol51no11/Printable.htm>, 2006.

ADDITIONAL SLIDES

The following slide is the minimally invasive knee surgery module.

If desired, please select the appropriate slides to include within this

presentation.

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MINIMALLY INVASIVE KNEE REPLACEMENT SURGERY

• SIGMA® Knees can be implanted using minimally invasive surgery

• Alignment affects:− How long your knee replacement lasts− Long-term success

ADDITIONAL SLIDES

The following 2 slides are thecomputer-assisted surgery module.

If desired, please select the appropriate slides to include within this

presentation.

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COMPUTER-ASSISTED SURGERY

What is computer-assistedsurgery (CAS)?

− An approach to knee replacement

− The patient’s anatomy is simulated and displayed on a computer

− Computer provides information about where to place the components

POTENTIAL BENEFITS OF CAS

• CAS guides surgeon in areas that are difficult to visualize

• Relays specific measurements not previously available to surgeons, such as implant alignment and angle of cuts

• Gives precise, accurate data on your specific anatomy

• Allows surgeons to make decisions about implant placement based on detailed data from the computer