Transcription Section 8.4:. Central Dogma I nformation flows in one direction: 1. Replication...
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Transcript of Transcription Section 8.4:. Central Dogma I nformation flows in one direction: 1. Replication...
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Transcription
Section 8.4:
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Central Dogma
Information flows in one direction:
1. Replication copies DNA
2. Transcription converts DNA into RNA
3. Translation interprets RNA message into string of amino acids or proteins
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What is a gene?A section of DNA that contains instructions on
how to make a specific protein.
Each gene has a locus (location) on DNA
Alleles are different forms of a gene
DNA located in the nucleus only
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What is transcription?Process of copying a
sequence of DNA (gene) to produce strand of RNA
RNA is a copy of a gene, not the entire strand of DNA.
Strand of RNA is complementary to DNA strand
Small segment can exit nucleus into cytoplasm
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Steps of Transcription
1. RNA Polymerase recognizes the start of the gene, attaches to the DNA strand and begins to unwind and unzip using helicase.
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2. RNA Polymerase adds RNA nucleotides to section of DNA being used as template.
3. Transcription complex moves along DNA, adding nucleotides, until complete gene is copied.
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4. Complete mRNA strand breaks off and moves out of nucleus.
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What does transcription produce?
mRNA – message that is ultimately translated into a protein
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Practice transcribing……Don’t forget to swap U for
T
DNA: A C G T T A C A G
RNA: U G C A A U G U C
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http://www.youtube.com/watch?v=4PKjF7OumYo
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Reflection #2Define Replication:Create the complementary strand for the DNA
sequence:
(original) A G C C T C A G T T C A G(new)Define Transcription:Translate the complementary strand from above into
mRNA:
(new)(mRNA)