Biomolecules Lecture Carbohydrates Lipids Proteins Nucleic Acids.
Topic 7 Nucleic Acids and Proteins. DNA Structure.
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Transcript of Topic 7 Nucleic Acids and Proteins. DNA Structure.
![Page 1: Topic 7 Nucleic Acids and Proteins. DNA Structure.](https://reader036.fdocuments.us/reader036/viewer/2022062515/56649d0a5503460f949dc75c/html5/thumbnails/1.jpg)
Topic 7
Nucleic Acids and Proteins
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DNA Structure
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DNA Structure cont’d
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DNA Replication
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Organization of DNA in Eukaryotes
• Replication Initiation Sites
• Where the replication of DNA begins (may also be known as O.O.R.)
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Nucleosomes• Globular structures that
contain 8 histone proteins, with DNA wrapped around 2 times
• Are connected to other nucleosomes by another histone protein (H1), known as a linker
• Essential for packaging DNA for mitosis/meiosis
• Involved in gene regulation
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DNA Folding
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DNA Folding
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Repetitive Sequences
• Repetitive base sequences that are not translated
• Sometimes called satellite DNA• Sequences between 5-300 bp• May be repeated as much as 10,000x• Constitute 10-40% of euk. genomes• Function unknown• A vey small portion of euk. DNA is single
copy/unique genes
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Introns and Exons