Radio Anatomy of Endocrine Glands Ppt1-14

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    Radioanatomy of theRadioanatomy of theEndocrine GlandsEndocrine Glands

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    What are endocrine glands?

    Glands that produce hormones andsecrete them directly in the bloodstream

    They do not have ducts

    Pituitary

    Thyroid

    Parathyroid Adrenals

    Pancreas

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    Pituitary GlandPituitary Gland

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    Pituitary GlandPituitary Gland

    Master gland of the endocrine systemMaster gland of the endocrine system

    Lies in the hypophyseal fossa (sellaLies in the hypophyseal fossa (sella

    turcica)turcica)

    Fossa is roofed by diaphragma sellaeFossa is roofed by diaphragma sellae

    Stalk of the hypophysis cerebri piercesStalk of the hypophysis cerebri pierces

    the diaphragma sellae and is attachedthe diaphragma sellae and is attached

    above to the floor of the third ventricleabove to the floor of the third ventricle

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    Pituitary GlandPituitary Gland

    Gland is oval in shapeGland is oval in shape

    Measures 8 mm (AP diameter) andMeasures 8 mm (AP diameter) and

    12 mm (transversely)12 mm (transversely)

    Weighs 500 mgWeighs 500 mg

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    RelationsRelations

    SuperiorlySuperiorly Diaphragma sellaeDiaphragma sellae

    Optic chiasmaOptic chiasma

    Tuber cineriumTuber cinerium

    Infundibular recess of 3Infundibular recess of 3rdrd ventricleventricle InferiorlyInferiorly

    Hypophyseal fossa and irregular venousHypophyseal fossa and irregular venouschannels between the two layers of durachannels between the two layers of dura

    covering itcovering it Sphenoidal air sinusesSphenoidal air sinuses

    On each sideOn each side

    Cavernous sinus with its contentsCavernous sinus with its contents

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    SubdivisionsSubdivisions

    AdenohypophysisAdenohypophysis

    Anterior lobeAnterior lobe

    Intermediate lobeIntermediate lobe

    Tuberal lobeTuberal lobe

    NeurohypophysisNeurohypophysis

    Posterior lobePosterior lobe

    Infundibular stemInfundibular stem

    Median eminence of the tuber cineriumMedian eminence of the tuber cinerium

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    Blood SupplyBlood Supply

    ArterialArterial

    Branches of internal carotid arteryBranches of internal carotid artery

    VeinsVeins Short veins emerge on the surface ofShort veins emerge on the surface ofthe gland and drain into thethe gland and drain into the

    neighbouring venous sinusesneighbouring venous sinuses

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    Radio-Imaging of PituitaryRadio-Imaging of Pituitary

    GlandGland

    Not visualized on Plain X-Ray of theNot visualized on Plain X-Ray of the

    skull, except for the sella turcica andskull, except for the sella turcica and

    clinoid processes housing theclinoid processes housing the

    pituitary glandpituitary gland

    Visualized onVisualized on

    CT Scan of brainCT Scan of brain

    MRI of brainMRI of brain

    PET Scan of brainPET Scan of brain

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    Radiograph of SkullRadiograph of Skull

    Lateral view showsLateral view shows

    the sella turcicathe sella turcica

    Pituitary glandPituitary gland

    resides on top of theresides on top of thesella turcicasella turcica

    The anterior andThe anterior and

    posterior clinoidposterior clinoid

    processes define theprocesses define theanterior and posterioranterior and posterior

    boundariesboundaries

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    Radiograph of SkullRadiograph of Skull

    Townes ViewTownes View

    shows dorsumshows dorsum

    sellae on top ofsellae on top of

    which lies thewhich lies thepituitary glandpituitary gland

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    A. Frontal LobeA. Frontal LobeB. Frontal Bone (SuperiorB. Frontal Bone (Superior

    Surface of Orbital Part)Surface of Orbital Part)

    C. Dorsum SellaeC. Dorsum Sellae

    D. Basilar ArteryD. Basilar ArteryE. Temporal LobeE. Temporal Lobe

    F. Mastoid Air CellsF. Mastoid Air Cells

    G. Cerebellar HemisphereG. Cerebellar Hemisphere CT Scan of

    Head

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    http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png
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    MRI of Brain

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    MRIofBrain

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    MRI of Brain

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    MRI of Brain

    http://www.med.harvard.edu/AANLIB/cases/caseM/mr1_t/019.gif
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    http://www.med.harvard.edu/AANLIB/cases/caseM/mr1_t/023.gif
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    PituitaryGland

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    http://upload.wikimedia.org/wikipedia/commons/6/6a/Pituitary_gland.png
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    Pituitary Gland

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    http://upload.wikimedia.org/wikipedia/commons/d/d7/Gray715.png
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    NormalOpticChiasm

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    PituitaryAdenoma

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    Opticnerves

    PituitaryAdenom

    a

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    Thyroid GlandThyroid Gland

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    Endocrine Gland

    regulates basalmetabolic rate

    stimulatessomatic and psychicgrowth

    plays importantrole in calciummetabolism

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    Ultrasound of Thyroid Gland

    http://www.delrioheart.com/images/thyroid.jpg
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    Thyroid GlandThyroid Gland

    Two lobes joined by theTwo lobes joined by theisthmusisthmus

    Lies against the C5,C6, C7Lies against the C5,C6, C7and T1 vertebrae claspingand T1 vertebrae claspingthe upper part of tracheathe upper part of trachea

    Each lobe extends fromEach lobe extends fromthe middle of the thyroidthe middle of the thyroidcartilage to the 4cartilage to the 4thth or 5or 5thth tracheal ringtracheal ring

    Isthmus extends from 2Isthmus extends from 2ndnd

    to 3to 3rdrd tracheal ringstracheal rings

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    Thyroid GlandThyroid Gland

    Lobes measure about 5 cm x 2.5 cmLobes measure about 5 cm x 2.5 cm

    x 2.5 cmx 2.5 cm

    Isthmus measures about 1.2 cm xIsthmus measures about 1.2 cm x

    1.2 cm1.2 cm

    Larger in females than in malesLarger in females than in males

    Increases in size during menstruationIncreases in size during menstruation

    and pregnancyand pregnancy

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    CapsulesCapsules

    True peripheral condensation ofTrue peripheral condensation ofconnective tissue of the glandconnective tissue of the gland

    False derived from pretrachealFalse derived from pretracheal

    layers of deep cervical fascialayers of deep cervical fascia False capsule forms the suspensoryFalse capsule forms the suspensory

    ligament of Berry which connects theligament of Berry which connects the

    lobe to the cricoid cartilagelobe to the cricoid cartilage A dense capillary plexus is presentA dense capillary plexus is present

    deep to the true capsuledeep to the true capsule

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    RelationsRelations

    Lobes are conical in shape and haveLobes are conical in shape and have

    ApexApex

    BaseBase

    Three surfaces lateral, medial andThree surfaces lateral, medial and

    posterolateralposterolateral

    Two borders anterior and posteriorTwo borders anterior and posterior

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    RelationsRelations

    Lateral surfacesLateral surfaces

    ConvexConvex

    Covered by sternothyhyoid,Covered by sternothyhyoid,

    sternohyoid, superior belly of omohyoidsternohyoid, superior belly of omohyoidand anterior border of sternomastoidand anterior border of sternomastoid

    musclesmuscles

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    RelationsRelations

    Medial surfaceMedial surface

    Two tubes trachea and esophagusTwo tubes trachea and esophagus

    Two muscles inferior constrictor andTwo muscles inferior constrictor and

    cricothyroidcricothyroid

    Two nerves extrenal laryngeal andTwo nerves extrenal laryngeal and

    recurrent laryngealrecurrent laryngeal

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    RelationsRelations

    Posterolateral surfacePosterolateral surface

    Carotid sheathCarotid sheath

    Overlaps common carotid arteryOverlaps common carotid artery

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    RelationsRelations

    Anterior borderAnterior border

    ThinThin

    Anterior branch of superior thyroid arteryAnterior branch of superior thyroid artery

    Posterior borderPosterior border ThickThick

    Inferior thyroid arteryInferior thyroid artery

    Anastomosis between superior and inferiorAnastomosis between superior and inferior

    thyroid arterythyroid artery

    Parathyroid glandParathyroid gland

    Thoracic duct (left side)Thoracic duct (left side)

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    RelationsRelations

    ApexApex

    Directed upwardsDirected upwards

    BaseBase

    At the level of 4At the level of 4 thth or 5or 5thth tracheal ringtracheal ring

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    RelationsRelations

    IsthmusIsthmus

    Connects the lower parts of the lobesConnects the lower parts of the lobes

    Two surfaces Two surfaces Anterior and posterior surfacesAnterior and posterior surfaces

    Two bordersTwo borders Superior and inferior bordersSuperior and inferior borders

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    Anterior surface covered byAnterior surface covered by

    Sternothyroid and sternohyoid musclesSternothyroid and sternohyoid muscles

    (R&L)(R&L) Anterior jugular veinsAnterior jugular veins

    Fascia and skinFascia and skin

    Posterior surface related toPosterior surface related to 22ndnd and 3and 3rdrd tracheal ringstracheal rings

    Isthmus

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    IsthmusIsthmus

    Upper borderUpper border

    Anastomosis between Right and LeftAnastomosis between Right and Left

    Superior Thyroid ArteriesSuperior Thyroid Arteries Lower borderLower border

    Inferior thyroid veins leave the gland atInferior thyroid veins leave the gland at

    this borderthis border

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    Blood SupplyBlood Supply

    ArterialArterial

    Superior thyroid artery branch ofSuperior thyroid artery branch of

    external carotid arteryexternal carotid artery

    Inferior thyroid artery branch ofInferior thyroid artery branch ofthyrocervical trunkthyrocervical trunk

    VeinousVeinous

    Superior thyroid veinSuperior thyroid vein Inferior thyroid veinInferior thyroid vein

    R di I i f Th idR di I i f Th id

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    Radio-Imaging of ThyroidRadio-Imaging of Thyroid

    GlandGland Not visualized on Plain X-Ray unlessNot visualized on Plain X-Ray unless

    calcifiedcalcified

    Visualized onVisualized on

    UltrasoundUltrasound

    CT scanCT scan

    MRIMRI

    Nuclear Medicine studyNuclear Medicine study

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    Coned apical radiograph of the upperthorax shows curvilinear calcificationin a thyroid adenoma, at the root of

    the neck, on the right side

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    CarotidArtery

    Trachea

    Thyroid Gland

    IsthmusStenohyoid andsternothyroid

    muscles

    Transverse Section of the Right Lobe of Thyroid

    Gland

    http://www.radiologyinfo.org/en/photocat/photos_pc.cfm?image=gen-us-thyroid.jpg&pg=us-thyroid
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    Sagittal Sectionof the ThyroidGland

    Transversesection of ThyroidGland

    http://www.ultrasound-images.com/images/suprasternal-lipoma-1e.jpghttp://www.ultrasound-images.com/images/suprasternal-lipoma-1c.jpg
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    Isthmus

    Right LobeLeft Lobe

    Trachea

    Transver

    seSectionof the

    Thyroid

    Gland

    http://www.ultrasound-images.com/images/thyroid-carcinoma-2b.JPGhttp://www.ultrasound-images.com/images/thyroid-carcinoma-2b.JPG
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    http://www.ultrasound-images.com/images/hashimotos-thyroiditis-full-1a.jpg
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    CT Scan of Thyroid GlandCT Scan of Thyroid Gland

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    Thyroid Scanning NuclearMedicine

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    Parathyroid GlandParathyroid Gland

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    Parathyroid GlandParathyroid Gland

    Two pairsTwo pairs

    SuperiorSuperior

    InferiorInferior

    Lie on the posterior border of the thyroidLie on the posterior border of the thyroidgland within the thyroid capsulegland within the thyroid capsule

    Oval or lentiform in shapeOval or lentiform in shape

    Measure about 6 x 4 x 2 mmMeasure about 6 x 4 x 2 mm Weighs 50 mgWeighs 50 mg

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    Parathyroid GlandParathyroid Gland

    Anastomotic artery between superiorAnastomotic artery between superior

    and inferior thyroid artery is a goodand inferior thyroid artery is a good

    marker because they lie close to itmarker because they lie close to it

    Superior parathyroid glands are moreSuperior parathyroid glands are moreconsistent in location near theconsistent in location near the

    middle of the posterior border of themiddle of the posterior border of the

    thyroid lobethyroid lobe

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    Blood SupplyBlood Supply

    ArterialArterial

    Inferior thyroid arteryInferior thyroid artery

    Anastomosis between superior andAnastomosis between superior and

    inferior thyroid arteriesinferior thyroid arteries

    VeinousVeinous

    Thyroid veinsThyroid veins

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    Radio-ImagingRadio-Imaging

    Not visualized on normal studiesNot visualized on normal studies

    Seen mostly when there is adenomaSeen mostly when there is adenoma

    Sometimes may be ectopic inSometimes may be ectopic in

    locationlocation

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    Transverse and longitudinal viewsof the left parathyroid gland

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    Immediatescan Delayed scans

    Nonspecific accumulation ofradioactivity in the region of the

    parathyroids

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    A 1.3 x 1.0 cm. nodule, relativelyhyperintense is seen posterior to the left lobeof the thyroid gland and lateral to theesophagus.

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    Injection of radioactiveInjection of radioactive

    material shows rapidmaterial shows rapid

    uptake by the thyroiduptake by the thyroid

    glandgland

    Delayed imageshows a retention of

    the radioactivematerial at theinferior pole of theleft thyroid arath roid

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    Adrenal GlandsAdrenal Glands

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    Adrenal GlandsAdrenal Glands

    A pair of glandsA pair of glands

    Lie in the epigastium at the upperLie in the epigastium at the upper

    pole of the kidneyspole of the kidneys

    In front of the crus of diaphragmIn front of the crus of diaphragm

    Opposite the vertebral end of the 11Opposite the vertebral end of the 11ththintercostal space and 12intercostal space and 12thth ribrib

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    Adrenal GlandsAdrenal Glands

    Right adrenal gland is triangular orRight adrenal gland is triangular or

    pyramidal in shapepyramidal in shape

    Left adrenal gland is semilunarLeft adrenal gland is semilunar

    Measures about 50 mm in height, 30 mmMeasures about 50 mm in height, 30 mmin breadth and 10 mm in thicknessin breadth and 10 mm in thickness

    1/31/3rdrd the size of kidneys in children andthe size of kidneys in children and

    1/301/30thth

    the size in adultsthe size in adults Weighs 5 gWeighs 5 g

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    Right Adrenal GlandRight Adrenal Gland

    An apexAn apex

    A baseA base

    Two surfaces anterior and posteriorTwo surfaces anterior and posteriorThree borders anterior, medial andThree borders anterior, medial and

    laterallateral

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    RelationsRelations

    Anterior surface devoid of peritoneumAnterior surface devoid of peritoneumexcept a small part belowexcept a small part below Inferior vena cava mediallyInferior vena cava medially Liver laterally andLiver laterally and Occasionally duodenum inferiorlyOccasionally duodenum inferiorly

    Posterior surfacePosterior surface Crus of diaphragmCrus of diaphragm

    Anterior borderAnterior border Hilum where veins emerge below the apexHilum where veins emerge below the apex

    Medial borderMedial border Right celiac ganglionRight celiac ganglion Right inferior phrenic arteryRight inferior phrenic artery

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    Left Adrenal GlandLeft Adrenal Gland

    Two ends Two ends Upper narrow endUpper narrow end

    Lower rounded endLower rounded end

    Two bordersTwo borders Medial convexMedial convex

    Lateral concaveLateral concave

    Two surfacesTwo surfaces AnteriorAnterior PosteriorPosterior

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    RelationsRelations

    Anterior surface Anterior surface cardiac end of stomachcardiac end of stomach

    Splenic arterySplenic artery

    PancreasPancreas

    Posterior surfacePosterior surface Kidney laterallyKidney laterally

    Left crus of diaphragm mediallyLeft crus of diaphragm medially

    Medial borderMedial border Left celiac ganglionLeft celiac ganglion Left inferior phrenic arteryLeft inferior phrenic artery

    Left gastric arteryLeft gastric artery

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    Blood SupplyBlood Supply

    ArterialArterial

    Superior adrenal artery branch ofSuperior adrenal artery branch of

    inferior phrenic arteryinferior phrenic artery

    Middle adrenal artery branch ofMiddle adrenal artery branch ofabdominal aortaabdominal aorta

    Inferior adrenal artery branch of renalInferior adrenal artery branch of renal

    arteryartery

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    Blood SupplyBlood Supply

    VeinousVeinous

    Each gland drained by one veinEach gland drained by one vein

    Right adrenal vein drains into inferiorRight adrenal vein drains into inferior

    vena cavavena cava Left adrenal vein drains into left renalLeft adrenal vein drains into left renal

    veinvein

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    Radio-ImagingRadio-Imaging

    Not seen on plain X-Ray unlessNot seen on plain X-Ray unless

    calcifications are presentcalcifications are present

    Visualized byVisualized by

    CT ScanCT Scan

    MRIMRI

    Ultrasonography seen better inUltrasonography seen better in

    children than in adultschildren than in adults

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    Imaging of Adrenal GlandsImaging of Adrenal Glands

    Located in the perirenal space near the upper pole ofeach kidney

    They may be shaped like the letters H, L, Y, T, or V

    They are less than 4 cm in length and less than 1.0 cm

    in thickness

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    CT ScanCT Scan

    They may be shaped like the letters H, L, Y, T, or V

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    Crus of diaphragm

    IVC

    Pancreas

    Spleen

    andSplenic

    Vessels

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    Ultrasound of adrenalUltrasound of adrenalmassmass

    Oblique sagittal imageOblique sagittal image

    of the abdomenof the abdomen

    demonstrates andemonstrates an

    isoechoic mass of theisoechoic mass of the

    left adrenal gland thatleft adrenal gland that

    is anterolateral to theis anterolateral to the

    aorta and medial toaorta and medial to

    the left kidneythe left kidney

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    Right

    AdrenalAdenoma

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    PancreasPancreas

    PP

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    PancreasPancreas

    Exocrine glandExocrine gland Secretes digestive enzymesSecretes digestive enzymes

    Endocrine glandEndocrine gland

    Secretes hormones like insulinSecretes hormones like insulin

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    The pancreas is 12-15 cm long and isThe pancreas is 12-15 cm long and islocated in the epigastriumlocated in the epigastrium

    Parts of the pancreas:Parts of the pancreas: HeadHead Uncinate processUncinate process NeckNeck

    BodyBodyTailTail

    The head and body lie outside theThe head and body lie outside theperitoneumperitoneum

    The head of the pancreas is surrounded byThe head of the pancreas is surrounded bythe duodenum as it makes a C-loopthe duodenum as it makes a C-looparound the pancreasaround the pancreas

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    The common bile duct traversesThe common bile duct traversesthrough the head of the pancreas andthrough the head of the pancreas and

    joins with the pancreatic duct at thejoins with the pancreatic duct at theampulla of Vater to empty bile into theampulla of Vater to empty bile into the

    second or descending part of thesecond or descending part of theduodenumduodenum Both the pancreatic ducts of SantoriniBoth the pancreatic ducts of Santorini

    and Wirsung drain the exocrineand Wirsung drain the exocrine

    pancreaspancreas

    Relationship to SurroundingRelationship to SurroundingSt tSt t

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    StructuresStructures

    HeadHead PosteriorPosterior

    Superior Mesenteric VeinSuperior Mesenteric Vein Splenic veinSplenic vein

    Inferior Vena CavaInferior Vena CavaTerminal portion of renal veinTerminal portion of renal vein Right crus of diaphragmRight crus of diaphragm

    AnteriorAnterior

    Transverse colonTransverse colon LateralLateral

    Bile ductBile duct

    Relationship to SurroundingRelationship to Surrounding

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    Relationship to Surroundingp g

    StructuresStructures

    NeckNeckAnteriorAnterior

    PylorusPylorus

    Omental bursaOmental bursaPosteriorPosterior

    SMVSMVBeginning of portal veinBeginning of portal vein

    Relationship to SurroundingRelationship to Surrounding

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    Relationship to Surroundingp g

    StructuresStructures

    BodyBody AnteriorAnterior

    Stomach separated by omental bursaStomach separated by omental bursa PosteriorPosterior

    Aorta and SMAAorta and SMA Left crus of diaphragmLeft crus of diaphragm Left kidney and adrenal glandLeft kidney and adrenal gland Left renal vein and splenic veinLeft renal vein and splenic vein

    InferiorInferiorTransverse mesocolon and splenicTransverse mesocolon and splenic

    flexureflexure Duodeno-jejunal junctionDuodeno-jejunal junction

    Relationship to SurroundingRelationship to Surrounding

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    p gp g

    StructuresStructuresTailTail

    The tail of the pancreas lies in theThe tail of the pancreas lies in thesplenorenal ligament and enters thesplenorenal ligament and enters thehilum of the spleen with splenichilum of the spleen with splenic

    vesselsvessels

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    Have a Good DayHave a Good Day