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Partnering with an outstanding initiative in life sciences and healthcare

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Drugs Patent Cliff

PharmaExpenditure

Control

HigherBarriersof Entry

InteroperabilityLack of HCP’sDigital Culture

Low success ofInternal R&D

resultsM&A

TechnologyPublic Purchase

Beyondthe PILL

PatientEmpowerment

The life sciences and healthcare industry is immersed in a period of transformation

Open Innovation is a tool to reinvent and to achieve better results and to meet new business needs

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THE BIOREGION OF CATALONIA:

A GROWING HEALTHCARE AND LIFE SCIENCES ECOSYSTEM

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Source: Biocat Directory (Feb. 2017)

871COMPANIES

95RESEARCHORGANIZATIONS

Excellence in research & a strong entrepreneurial spirit: key drivers in the development of the BioRegion

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BIOCAT:

BUILDING NOW WHAT THE ECOSYSTEM NEEDS NEXT

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Biocat dynamizes all the stakeholders of the BioRegion to transform knowledge and technology into economic growth, and to create a social impact

STRATEGY:

• SHARING KNOWLEDGE AND PROMOTING THE BIOREGION

• ACCELERATING ENTREPRENEURSHIP AND COMPANIES GROWTH

• TECHNOLOGY TRANSFER AND VALORISATION

Biocat acts as a strategic agent and catalyst of the Catalan healthcare and life sciences

ecosystem

RESEARCH

COMPANIES &

START-UPS

ADMINISTRATION

CAPITAL

TALENT

PROGRAMS

KEY ELEMENTS OF THE BIOREGION:

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Our goals:• Promote innovation within the healthcare sector (ecosystem programs)

• Train and provide talent to the life science sector

• Create startups with valuable products and business models

• Collaborate and scale the program at European level

• Position the BioRegion at international level

BIOCAT develops programs to accelerate healthcare entrepreneurship

The talent development initiative of Biocat to accelerate healthcare entrepreneurship

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MOEBIO programs

Program to develop entrepreneurs and future leaders in healthcare innovation

Educational sessions covering key aspects in healthcare, innovation, management and entrepreneurship

Program that facilitates the acceleration of healthcareinnovations emerging from academic labs into commercialization

• Direct impact to Hospitals • Indirect impact to all the stakeholders

• Direct impact to Research and Tech Transfer Offices

• 9 months full-time • Hours in a day • 12-week part-time

• 12 people • Last year: 40 different people • 8 teams

• Individuals who want to enter healthcare & life sciences

• Entrepreneurs, managers and executives of healthcare organizations, students, recent graduates and other professionals

• Researchers (in hospitals or in research institutions) with a potential business technology and early start-ups

• Partners: Stanford Biodesign / EIT Health Program • -- • Partners: CIMIT / EIT Health Program

(in process)

• Connect with local and international ecosystems (Silicon Valley, Galway,Stockholm and Oxford)

• Connect to local ecosystems• Connect with local and international

ecosystem (Boston, France and Holland)

• 2013 • 2014 • 2018

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d·HEALTH BARCELONA:

A PROGRAM TO TRANSFORM UNMET NEEDS INTO INNOVATIVE MARKETABLE SOLUTIONS

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Inspired in the prestigious Stanford University’s Biodesign Fellowship, d·HEALTHBarcelona is a 9-month Program which provides disruptive education, training and mentorship to 12 multidisciplinary Fellows that experience a full cycle of innovation in healthcare.

After a clinical immersion in a top hospital of Barcelona, fellows select the most valuable unmet healthcare needs and transform them into innovative solutions, through the biodesign methodology. They identify, invent and implement a viable business proposition to be place in the market.

Fellows receive training in subjects such as design thinking or creative leadership through classes taught by over 50 international experts. They also benefit from the vibrant BioRegion ecosystem and are able to attend the most interesting events to improve their learning process and network with other entrepreneurs and KOL.

“Are you working on something that can change the world? Yes or no? For 99% of the people on the planet, the answer is no, and the fact of the matter is, we should be” Larry Page - co-founder of Google

d·HEALTH Barcelona: Transforming real unmet needs into innovative marketable solutions

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BIODESIGN CREATIVE LEADERSHIPLEAN STARTUP

A process for identifying, inventing and implementingnew products and services in

healthcare through innovativeapproaches such as Design

Thinking

A customer-centric approach to validate your business ideas with

customer experiments/tests beforescaling them

A transformative educationalapproach to develop businesscreativity, personal masteryand enterprising leadership

Join a successful methodology to enrich medtech innovation

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2014

2015

2016

2017(ONGOING EDITION)

ICT(Thorax Institute)

Neonatology Functional rehabilitation

ICMDiM(Institute of Digestive

and Metabolic Diseases)

ICOF (Institute Ophthalmology)

CardiologyFunctional

rehabilitation

Gynecology and Obstetrics

ICNU (Institute Nephrology and

Urology)

Functional rehabilitationEndocrinology

9 projects developed after the 3 first editionsThe 5th edition of d·HEALTH Barcelona will start on January 2018

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Every year our fellows impact +1,100 people (patients, HCPs, management,…)

CLINIC HSJD GUTTMANN TOTAL KEY BENEFIT

HCPs 400 100 75 575 Introduction of innovation culture in the department

HOSPITALMANAGERS 10 15 10 35 Innovation as a new corporate priority

PATIENTS & STAKEHOLDERS 124 102 154 380 Their voice is heard and incorporated in

the product dev.

ENTREPRENEURS 10 Knowledge, contacts, experience, mistakes transferred

FACULTY 65 Connections at the industry level

INVESTORS 5 Access to capital and dealflow

MENTORS 15 Knowledge and experience being transferred.

RESEARCHCENTERS 25 Technology Transfer. Licences from

patents hold by Research Centers

TECHNOLOGICALCENTERS 30 Prototyping. First proofs of concept.

This is the only way to CHANGE HEALTHCARE at a systemic level

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Product: Solution for chronic constipation in the form of a wearable medical device that simulates the techniques of professional massage therapists

Current status: On the market. Company incorporated in 2014 (usMIMA)

Team: Institut Guttmann, 2013-2014

Both projects have obtained funding from H2020, through the SME instrument. In total, the funds raised are 2.3 M €

Product: Medical device for anal incontinenceCurrent status: Product development. Company’s incorporation expected for the end of 2016

Team: Hospital Clínic, 2015

Our success stories

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Through over 3,000 unmet clinical needs and more than 1,250 interviews, we are improving healthcare at a systemic level

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The teams develop a deep analysis on the final top 12 needs selected

Information included in the report:

Definition of the problem (data on prevalence, incidence…)

Clinical impact (cost of the clinical problem…)

Analysis on the current solutions (analysis of current treatments, risk and benefits of each of them, unmet needs of the current solutions, weaknesses of the current treatments and potential opportunities of innovation…)

Stakeholder analysis

Discovering, understanding & reformulating unmet clinical needs to transform them into valuable knowledge

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More than 70 experts from all over the world collaborating with the program

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More than 70 experts from all over the world collaborating with the program

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• 1ST Prize BIOEMPRENEDOR XXI (2014)

• 1ST Prize Biotecnología y Salud del Everis Award

(2015)

• “TOP 10 innovative startups with social impact in

Spain” by TEDx Binnenhof/European

Commission and ENISA (2015)

• “Seal of Excellence” of the European

Commission/Horizon 2020 (2016)

• Head start Proof of concept EIT Health Award

(2016)

• Unique Spanish company participating in

MassChallenge UK accelerator

Our companies are recognised both at nationaland international level

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1. Digitalhealth.careers (https://goo.gl/ygwx5P )

2. Mobile World Capital (https://goo.gl/NbqRai )

3. Tech EU (https://goo.gl/kZPIOD )

4. HealthStartup (https://goo.gl/My2y3z )

MOEBIO is ranked as one of the most important accelerators in Europe

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INSPIRED BY:

COLLABORATOR HOSPITALS:

PARTNERS 2016:

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Partners

UNIVERSITY SPECIFIC DEGREE: INNOVATION FELLOWSHIP OF:

COLLABORATORS:

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OTHER MOEBIO PROGRAMS

SHORT PROGRAMS

CRAASH

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Short Programs: learn from the best of d·HEALTHBARCELONA classesMOEBIO Short Programs are educational programs of maximum 20 hours covering key aspects in healthcare, innovation, management and entrepreneurship. Short programs are addressed at professionals willing to broaden their skills set and acquire new practical knowledge about today’s most pressing issues, and this over a short period of time.

Short programs are addressed to…

Entrepreneurs, managers and executives of healthcare organizations, students, recent graduates and other professionals interested in expanding their areas of expertise to healthcare and entrepreneurship

2017 edition:

1.Understanding Healthcare Systems

2.Update on the Life Sciences Industry

3.Entrepreneurship and Management

4.Medical Devices I: Product Development

5.Medical Devices II: Market access

Partners of d·HEALTH have access to some “exclusive” classes that are not available to the general public

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CRAASH: New Program coming in Spring 2018

CRAASH is a 10-week part time program in which teams composed of clinicians, technologists and entrepreneurs that have developed potential healthcare innovations engage with experienced HealthTech entrepreneurs. Team members will learn-by-doing, getting out of the lab to transform technologies into viable business propositions.

CRAASH is addressed to…

8 teams of three members

(clinician, technologist and

entrepreneur) coming from top

academic and research

institutions

It blends the decades of experience from CIMIT's pioneering work facilitating innovations and innovators

• Uncovering stakeholder needs and buying dynamics

• Developing and validate value propositions and business models

• Creating pitches to target funders

• Exploring new markets

In collaboration with:

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CRAASH: A Boston successful program in our ecosystem

Program Refinement

Program Feedback

Call for teams Biocat provides feedback based on CIMIT proposed selection criteria

CIMIT evaluates teams/projects and final selection of the teams

3 days

Kickoff In-person Session Barcelona

• Customer/Stakeholder Interviewing

• Defining Clinical Needs and the Value Proposition

8 weeks

Weekly Web-Meeting Sessions

Web-Meeting Structure9:00am–11:00am

Part 1: 9:00 - 10:00 amTeam Presentations & Feedback(~15 minutes for each team)

Part 2: 10:00 - 11:00 amWeekly Lecture Topics/Discussions

3 days

Close-out In-person Session Boston

• Team "Pitches“

• Feedback

Team solicitation

Team selection

ProgramDelivery

Barcelona Virtual Boston

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WHAT CAN WE DO FOR YOU?

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Collaborate with MOEBIO d·Health Barcelona

BUSINESSOPORTUNITIES

BRAND RECOGNITION

TRAINING

• Priority access to innovative business opportunities (final solution)

• Right of first look to the top clinical needs identified during the program (needs top 12 and top 50)

• Have a “business liaison” working closely with of one the teams

• Clinical setting knowledge: reinforce the company knowledge of the current dynamics and future trends of the main clinical areas of the hospitals

• Meeting with the KOL professionals

• Training in innovative methodologies developed at the hospitals

• Exclusive access to a limited number of lessons/workshops of interest of the company included in the d·HEALTH learning program

• 2 Invitations to attend 10 sessions of the training package opened to the ecosystem: the Short Programs

• Visibility in all d·HEALTH marketing materials (website, leaflets, e-mailings, social media, press releases and events)

Being part of a successful and reknowed program

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Collaborate with MOEBIO CRAASH

BUSINESSOPORTUNITIES

BRAND RECOGNITION

• Priority access to healthcare innovations emerging from academic labs (in Spain and Europe) selected after CIMIT due diligence process

• Have a industry veteran working closely with one the teams

• Healthtech setting knowledge: reinforce the company knowledge of the some current dynamics and future trends in healthcare innovations from the top research centers in Europe

• Gain access to the Leading Research Centers and top mentors from Boston and Europe

• Visibility in all CRAASH marketing materials (website, leaflets, e-mailings, social media, press releases and events)

Being part of a new and disruptive program for early R&D projects

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FOLLOW US AT:@moebiobarcelona

blog.moebio.orges.linkedin.com/in/moebiobarcelonawww.facebook.com/moebiobarcelona

MORE INFORMATION AT:WWW.MOEBIO.ORG

AN INITIATIVE OF: INNOVATION FELLOWSHIP OF: