PLASMA INDUSTRIE HERAUSFORDERUNGEN UND … Industrie... · im Jahr 2011. Pharmaceutical Industry...
Transcript of PLASMA INDUSTRIE HERAUSFORDERUNGEN UND … Industrie... · im Jahr 2011. Pharmaceutical Industry...
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ARGEMagdeburg 18. & 19. November 2016
PLASMA INDUSTRIEHERAUSFORDERUNGEN UND
MGLICHKEITEN
Die Unterschiede zwischen Plasma- und PharmaindustriePatrick Robert
The Marketing Research Bureau, Inc.
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Die in dieser Prsentation verwendeten Diagramme und Tabellen wurden aus Daten zusammengestellt, die aus Umfragen stammen, durchgefhrt vom Marketing Research Bureau (MRB) in rund 50 Lndern und verffentlicht in verschiedenen MRB Berichten.
Alle Daten und Informationen stammen aus Quellen, die in der Regel die ffentlich zugnglich sind. Ihre Genauigkeit ist nicht garantiert und das Marketing Research Bureau bernimmt keine Haftung fr deren Gebrauch. 2016
METHODE
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Worin unterschiedt sich die Plasmaindustrie von der Pharmaindustrie?
INHALT
Ausgangsstoff und Verarbeitung Vertriebskanle und Mrkte Der menschliche Faktor
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Die Unterschiede zwischen Plasma und Pharmaindustrie:
INHALT
Ausgangsstoff und Verarbeitung Vertriebskanle und Mrkte Der menschliche Faktor
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Kostenstruktur der Herstellung von Plasmaprparatenund chemisch hergestellten Pharmazutika - 2011
* Beinhaltet allgemeine Verwaltungskosten in der PharmaindustrieQuelle: Industrieberichte & Schtzungen, 2011
Pharmaceutical Industry
14.0%
30.0%
25.0%
6.0%
25.0%
Plasma Industry
57.0%
10.0%
9.0%
10.0%
14.0%
Manuf. Costs & Raw Materials
Sales & Marketing
Research & Development
General Administration
Other *
In der Plasmaindustrie stellt der Ausgangsstoff einen signifikant hheren Anteil der Produktionskosten dar als in der Pharmaindustrie: 57% vs. 14% im Jahr 2011
Chart6
0.14
0.3
0.25
0.06
0.25
Pharmaceutical Industry
Old_Data2004
4/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials70%
Sales & Marketing13%
Research & Development7%
General Administration5%
Other *5%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials19%
Sales & Marketing34%
Research & Development15%
General Administration0%
Other *32%
100%
* Includes General Administration in the Pharmaceutical Industry
Old_Data2004
Plasma Industry
Nu-Data2011
4/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials57%
Sales & Marketing10%
Research & Development9%
General Administration10%
Other14%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials14%
Sales & Marketing30%
Research & Development25%
General Administration6%
Other25%
100%
Pharmaceutical Industry
Nu-Data2011
Plasma Industry
Pharmaceutical Industry
Chart7
0.57
0.1
0.09
0.1
0.14
Plasma Industry
Old_Data2004
4/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials70%
Sales & Marketing13%
Research & Development7%
General Administration5%
Other *5%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials19%
Sales & Marketing34%
Research & Development15%
General Administration0%
Other *32%
100%
* Includes General Administration in the Pharmaceutical Industry
Old_Data2004
Plasma Industry
Nu-Data2011
4/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials57%
Sales & Marketing10%
Research & Development9%
General Administration10%
Other *14%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials14%
Sales & Marketing30%
Research & Development25%
General Administration6%
Other *25%
100%
Pharmaceutical Industry
Nu-Data2011
Plasma Industry
Pharmaceutical Industry
-
Pharmaceutical Industry
19.0%
34.0%15.0%
32.0%
Kostenstruktur der Herstellung von Plasmaprparatenund chemisch hergestellten Pharmazutika - 2004
* Beinhaltet allgemeine Verwaltungskosten in der PharmaindustrieQuelle: Industrieberichte, 2005
Plasma Industry
70.0%
13.0%
7.0%
5.0%5.0%
Manuf. Costs & Raw Materials
Sales & Marketing
Research & Development
General Administration
Other
Seit 2004 haben sich die Anteile anderer Komponenten der Arzneimittelkosten erhht: Im Jahr 2004 betrug der Rohstoff 70% im Vergleich zu 57% im Jahr 2011.
Chart3
0.19
0.34
0.15
0
0.32
Pharmaceutical Industry
Old_Data2004
4/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials70%
Sales & Marketing13%
Research & Development7%
General Administration5%
Other5%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials19%
Sales & Marketing34%
Research & Development15%
General Administration0%
Other *32%
100%
* Includes General Administration in the Pharmaceutical Industry
Old_Data2004
Plasma Industry
Nu-Data2011
4/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials57%
Sales & Marketing10%
Research & Development9%
General Administration10%
Other14%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials14%
Sales & Marketing30%
Research & Development25%
General Administration6%
Other25%
100%
Pharmaceutical Industry
Nu-Data2011
Plasma Industry
Pharmaceutical Industry
Chart1
0.7
0.13
0.07
0.05
0.05
Plasma Industry
Sheet1
China Throughput Calculation4/23/07
ThroughputThroughputCapacity
InitialfiguresCorrectedfigures
-20%
20072010200720102010
400160320128400
25012020096500
450160360128400
35012028096400
200160160128400
70012056096200
801206496500
30012024096600
100216801731,000
200220160176400
10016080128500
10025680205600
200160160128400
3,4302802,744224600
12096300
12096500
12096300
1601281,000
160128400
160128450
8064300
12096200
3428500
3,4462,75710,850
2004
4/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials70%
Sales & Marketing13%
Research & Development7%
General Administration5%
Other5%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials19%
Sales & Marketing34%
Research & Development15%
General Administration0%
Other *32%
100%
* Includes General Administration in the Pharmaceutical Industry
2004
Plasma Industry
2011
4/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials57%
Sales & Marketing10%
Research & Development9%
General Administration10%
Other14%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials14%
Sales & Marketing30%
Research & Development25%
General Administration6%
Other25%
100%
Pharmaceutical Industry
2011
Plasma Industry
Pharmaceutical Industry
-
Plasma Industry
57.0%
10.0%
9.0%
10.0%
14.0%
Pharmaceutical Industry
14.0%
30.0%
25.0%
6.0%
25.0%
Weltweiter Pharmamarkt: $1.052,3 Milliarden (IMS), inkl. Generika
Weltweiter Markt fr Plasmaprparate : $19,7 Milliarden
Der weltweite Absatz der Plasmaindustrie stellt 0,18% des weltweiten Absatzes der Pharmaindustrie dar
Chart1
0.57
0.1
0.09
0.1
0.14
Plasma Industry
Sheet1
China Throughput Calculation4/23/07
ThroughputThroughputCapacity
InitialfiguresCorrectedfigures
-20%
20072010200720102010
400160320128400
25012020096500
450160360128400
35012028096400
200160160128400
70012056096200
801206496500
30012024096600
100216801731,000
200220160176400
10016080128500
10025680205600
200160160128400
3,4302802,744224600
12096300
12096500
12096300
1601281,000
160128400
160128450
8064300
12096200
3428500
3,4462,75710,850
2004
6/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials70%
Sales & Marketing13%
Research & Development7%
General Administration5%
Other5%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials19%
Sales & Marketing32%
Research & Development15%
General Administration6%
Other *28%
100%
* Includes General Administration in the Pharmaceutical Industry
2004
Plasma Industry
2011
6/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials57%
Sales & Marketing10%
Research & Development9%
General Administration10%
Other14%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials14%
Sales & Marketing30%
Research & Development25%
General Administration6%
Other25%
100%
Manuf. Costs & Raw Materials
Sales & Marketing
Research & Development
General Administration
Other *
Pharmaceutical Industry
1
1
1
1
2011
Plasma Industry
Pharmaceutical Industry
Chart2
0.14
0.3
0.25
0.06
0.25
Pharmaceutical Industry
Sheet1
China Throughput Calculation4/23/07
ThroughputThroughputCapacity
InitialfiguresCorrectedfigures
-20%
20072010200720102010
400160320128400
25012020096500
450160360128400
35012028096400
200160160128400
70012056096200
801206496500
30012024096600
100216801731,000
200220160176400
10016080128500
10025680205600
200160160128400
3,4302802,744224600
12096300
12096500
12096300
1601281,000
160128400
160128450
8064300
12096200
3428500
3,4462,75710,850
2004
6/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials70%
Sales & Marketing13%
Research & Development7%
General Administration5%
Other5%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials19%
Sales & Marketing32%
Research & Development15%
General Administration6%
Other *28%
100%
* Includes General Administration in the Pharmaceutical Industry
2004
Plasma Industry
2011
6/23/07
Comparative Cost Structures of Plasma Protein Therapies and Chemical-based Pharmaceuticals
Plasma
Industry
Manuf. Costs & Raw Materials57%
Sales & Marketing10%
Research & Development9%
General Administration10%
Other14%
100%
Pharmaceutical
Industry
Manuf. Costs & Raw Materials14%
Sales & Marketing30%
Research & Development25%
General Administration6%
Other25%
100%
Manuf. Costs & Raw Materials
Sales & Marketing
Research & Development
General Administration
Other *
Pharmaceutical Industry
1
1
1
1
2011
Plasma Industry
Pharmaceutical Industry
-
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION1990 - 2014
Recovered & Source in Liters
42.645.0
16.4
19.722.3
26.1
27.2
24.525.9
33.636.8
0.0
5.0
10.0
15.0
20.0
25.0
30.0
35.0
40.0
45.0
50.0
1990 1993 1996 1999 2002 2004 2007 2010 2012 2013 2014
Total volume in 2014: 45.0 Million Liters
Plasmagewinnung hngt von Faktoren ab, die unabhnig von der Fraktionierungsindustrie sind, wie z.B. die wirtschaftliche Lage (Source-Plasma) und die Nachfrage nach Erythrozyten und anderen Blutbestandteilen (Recovered- Plasma)
In den Jahren 2003/2004 fhrte ein berschuss an Plasma zu einer Korrektur. Die jhrliche Wachstumsrate des Plasmas betrug 6,3% ber zehn Jahre (2004-2014) und 4,3% ber 24 Jahre (1990-2014).
Chart1
16.38
19.661
22.323
26.119
27.175
24.497
25.925
33.643
36.792
42.56665
44.95875
Total volume in 2014: 45.0 Million Liters
Total
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION1990 - 2014Recovered & Source in Liters
Population_2014
World Population 2014 (UN)
2014
Middle East/Africa1,13615.7%
North America3544.9%
Asia & Pacific4,39060.7%
South America6178.5%
Europe74110.2%
Total7,238100.0%
Population_2014
Source: PopulationReference Bureau
World Population by Region - 2014
Plasma_Supply_Regions
3/10/12
Liters of Plasma (1000 liters)
RecoveredSourceTotal
Asia & Pacific1,4616,2277,689
Middle East/ Africa32210042228
North America2,09026,48228,5716
Latin America44260502
Europe4,4333,3437,775
Total8,74736,21244,959
Ratio Recovered to Source PlasmaRatio Recovered to Source Plasma
RecoveredSourceRecovered+Source
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Plasma_Supply_Regions
Total recovered & source: 44,959,000 liters
Plasma for Fractionation by Region 2014(Recovered & Source)
Plasma_Supply_Country
3/10/12
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Australia325256581325256581
China *- 04,9504,950- 05,2005,200
India352- 0352352- 0352
Japan402554956402554956
Hong Kong3053530535
Korea (Rep)201210411201210411
Malaysia23- 02323- 023
New Zealand51- 05151- 051
Singapore82108210
Taiwan30- 03030- 030
Thailand30- 03030- 030
Other Asia10- 01010- 010
Sub-total Asia & Pacific1,4615,9777,4391,4616,2277,68917.1%
Argentina14051451405145
Brazil140- 0140140- 0140
Chile15- 01515- 015
Cuba1001511510015115
Mexico5- 055- 05
Uruguay12- 01212- 012
Venezuela204060204060
Other Latin America10- 01010- 010
Sub-total Latin America44260502442605021.1%
Canada24042432404243
United States *1,95024,15326,1031,85026,47828,328
Sub-total North America2,19024,15726,3462,09026,48228,57163.6%
South Africa *10051051005105
Iran1409523514095235
Egypt5- 055- 05
Morocco15- 01515- 015
Israel47- 04747- 047
Other Middle East/Africa15- 01515- 015
Sub-total Middle East/Africa3221004223221004220.9%
* 2014 Data
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Austria5056061050560610
Belgium179- 0179179- 0179
Bulgaria15- 01515- 015
Croatia25- 02525- 025
Czech Republic5045050050450500
Denmark60- 06060- 060
Finland60- 06060- 060
France6898477368984773271.41
Germany *1,2051,8503,0551,0201,7622,782
Greece5- 055- 05
Hungary81371188137118
Italy836- 0836836- 0836
Latvia10- 01010- 010
Lithuania12- 01212- 012
Macedonia5- 055- 05
Netherlands150150300150150300
Norway451055451055
Poland2602028026020280
Russia *110120230150270420
Serbia15- 01515- 015
Slovakia15- 01515- 015
Slovenia25- 02525- 025
Spain350- 0350350- 0350
Sweden145- 0145145- 0145
Switzerland80- 08080- 080
Ukraine70- 07070- 070
Other Europe30- 03030- 030
Sub-total Europe4,5773,2817,8584,4333,3437,77517.3%
World Total8,99233,57542,5678,74736,21244,959100.0%
- 019%81%100%
42,56744,959
RecoveredApheresisTotal
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Kg. x 1000Kg. x 1000
1,0641,124
741741
170.267179.835
141141
Total: 8,992,000 liters
Total recovered: 8,747,000 liters
Plasma for Fractionation by Region 2014(Recovered)
Total: 33,575,000 liters
Total source 36,212,000 liters
Plasma for Fractionation by Region 2014(Source)
Recovered
Source
Percentage Recovered & Source Plasma by Region - 2014
Charts_Plasma_Coll
Annual compounded growth rate (ACGR) from 1996 to 2012. Source plasma for fractionation0
Annual compounded growth rate (ACGR) from 1996 to 2012. Recovered plasma for fractionation0157,356
Annual compounded growth rate (ACGR) from 1996 to 2012. Total source & recovered plasma for fractionation01,123,969
COMMERCIAL & NON-PROFIT ORGANIZATIONS
(Thousand Liters)
GrowthGrowth
WORLD1990199319961999200220042007201020122013201410 years24 years
Source Plasma9.812.814.917.618.616.318.225.627.933.636.28.3%5.6%
Recovered Plasma6.66.97.48.58.58.27.88.18.99.08.70.7%1.2%
Total16.419.722.326.127.224.525.933.636.842.645.06.3%4.3%
Annual Growth Rate6.3%4.3%5.4%1.3%-5.1%1.9%9.1%4.6%7.6%10.5%
Source Plasma9,81712,75614,92517,64818,63316,32818,15725,58327,85533,57536,212
Recovered Plasma6,5636,9057,3988,4718,5428,1697,7688,0608,9378,9928,747
Total16,38019,66122,32326,11927,17524,49725,92533,64336,79242,56744,959
Increment (Liters x 000)3,2812,6623,7961,056-2,6781,4287,7183,1495,7752,392
Charts_Plasma_Coll
Global volume in 2014: 45.0 Million Liters
Source Plasma
Recovered Plasma
Source Plasma
Recovered Plasma
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION 1990 - 2014Recovered & Source in Liters
Charts_Fractionators
65 Plasma Fractionators worldwide
Europe 1515
Middle East/Africa 44
Latin America 44
Asia & Pacific 3838
North America 44
65
Plasma Throughput 42.6 million liters worldwide
Europe18,000
Middle East/Africa1,450
Asia & Pacific6,500
Latin America330
North America14,150
40,430
33000
0.82
Total volume in 2014: 45.0 Million Liters
Total
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION1990 - 2014Recovered & Source in Liters
Charts_Fractionators
TOTAL : 71 FRACTIONATION PLANTS
Total Number of Fractionation Plants: 65
REGIONAL DISTRIBUTION OF FRACTIONATION PLANTS 2014
IGG_Charts
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014North America69.746%
(Kilograms)RoW1.91%
Europe42.028%
Initial file, amended one table belowMiddle East3.72%
1992*1994*1996*19982000200320052008201020122014Asia & Pacific27.418%
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703Latin America7.05%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006100%
Asia & Pacific4,3284,4424,6645,2759,3839,6959,7968,48716,97618,21323,476
Latin America1782931,1386388751,6372,2172,8854,1034,5836,979
Middle East---6351,1931,6231,8451,7713,8253,8303,739
Oceania485686473181,0281,5281,7542,8182,9053,4393,908
Africa631183207335978129228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77685,151107,293122,332151,680
1992-1996-Asia and Mid-East together
Initial file, amended one table below
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014
(Kilograms)
1992*1994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,384
Latin America1782931,1386388751,6372,2172,8854,1044,5836,979
Middle East1002004006351,1931,6231,8451,7703,8253,8303,739
RoW631183207335978119228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,680
* Includes Oceania (Australia/NZ)
* Amended: Middle East has been carved out from Asia and Pacific (100 Kg. in 1992, 200 in 1994 and 400 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
19921994199619982000200320052008201020122014
9.914.517.617.119.727.031.643.151.459.469.7
5.27.811.111.914.615.820.725.226.230.942.0
4.34.84.95.610.411.211.611.319.921.727.4
0.20.31.10.60.91.62.22.94.14.67.0
0.10.20.40.61.21.61.81.83.83.83.7
0.10.10.30.70.60.80.90.91.91.91.9
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0
1992*1994*1996*19982000200320052008201020122014
North America9.914.517.617.119.727.031.643.151.459.469.7
Europe5.27.811.111.914.615.820.725.226.230.942.0
Asia & Pacific*4.34.84.95.610.411.211.611.319.921.727.4
RoW0.30.61.92.02.74.15.05.59.810.312.6
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
Annual
Growth rate
2005-2015
19921994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,7039.2%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,0068.2%
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,38410.1%
RoW3406101,8582,0052,6654,0724,9845,5419,84110,32812,58710.8%
Total (000)19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,6809.2%
0
Total (MM)19.727.735.536.647.458.268.885.2107.3122.3151.7
TOTAL : 71 FRACTIONATION PLANTS
Global Plasma Throughput 2014: 42.2 million liters
REGIONAL DISTRIBUTION OF FRACTIONATION THROUGHPUT 2014
IGG_Charts
* Includes Australia & New Zealand
North America
Europe
Asia & Pacific*
RoW
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION FROM 1992 TO 2014(Metric Tons)
Pharma_Mkt
IMS DataPharma market
Africa13,213,166,396
Asia major193,119,667,483
Central America11,201,994,793
Europe - Key Five211,585,009,569
Europe - Other105,953,031,494
Middle East5,505,595,391
North America403,418,901,401
South America67,665,782,195
Southeast Asia40,646,773,783
Total1,052,309,922,505
Africa & Middle East18,718,761,787
Asia & Pacific233,766,441,266
Latin America78,867,776,988
Europe317,538,041,063
North America403,418,901,401
Tally- 0
Africa & Middle East1.8%18,718,761,787
Asia & Pacific22.2%233,766,441,266
Latin America7.5%78,867,776,988
Europe30.2%317,538,041,063
North America38.3%403,418,901,401
Total100.0%- 0
MRB DataPlasma market
Latin America5.3%
North America41.6%
Africa & Middle East4.3%
Asia & Pacific20.9%
Europe27.9%
Total100.0%
0.2%
Total (MM)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION (Percentage of Metric Tons)Total: 151.7 Metric Tons
Pharma_Mkt
Total: 8,992,000 liters
Total market $1,052.3 Billion
The Global Pharmaceutical Market by Region 2014(Source: IMS)
Albumin_Chart
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.71176
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific121.9163.5162.0175.0176.2157.4157.5199.9237.8270.0412.4North America169.7
Latin America8.58.632.223.122.824.529.232.934.238.143.7Latin America43.7
Middle East---12.215.221.122.625.940.540.548.5Europe144.7
Oceania5.04.64.94.74.64.95.06.56.96.97.6Asia & Pacific420.0
Africa4.34.96.16.17.610.611.312.920.220.224.3Middle East/Africa72.8
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
1992-1996-Asia and Mid-East together
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific117.9157.5154.0175.0176.2157.4157.5199.9237.8270.0412.4
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East4.06.08.012.215.221.122.625.940.540.548.5
Oceania5.04.64.94.74.64.95.06.56.96.97.6
Africa4.34.96.16.17.610.611.312.920.220.224.3
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. in 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
Tally0.00.00.00.00.00.00.00.00.00.00.0
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific122.9162.1158.9179.7180.8162.3162.5206.4244.8276.9420.0
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East/Africa8.310.914.118.322.831.734.038.860.760.772.85.4%
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.96.9%
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. In 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand
Total: 8,992,000 liters
Total market $19.7 Billion
The Global Plasma Proteins Market by Region 2014(Source: MRB)
Albumin_Chart
North America
Europe
Asia & Pacific
Latin America
Middle East/Africa
WORLDWIDE ALBUMIN SALES BY REGION FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES BY REGION(Percentage of Metric Tons)Total: 850.9 Metric Tons
-
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION 1990 - 2014Recovered & Source in Liters
18.2
33.6
36.2
9.0 8.7
25.627.9
16.3
18.617.6
14.912.8
9.8
6.6 6.9 7.48.5
8.5 8.2 7.8 8.18.9
0.0
5.0
10.0
15.0
20.0
25.0
30.0
35.0
40.0
1990 1993 1996 1999 2002 2004 2007 2010 2012 2013 2014
Global volume in 2014: 45.0 Million Liters
Source Plasma
Recovered Plasma
Die jhrliche Wachstumsrate des Source-Plasmas betrug ber 10 Jahre (2004-2014) 8,3% und 0,7% fr Recovered Plasma. ber 24 Jahre (1990-2014) stieg die Source-Plasmagewinnung um 5,6% pro Jahr und 1,2% fr Recovered Plasma.
Chart2
9.8176.563
12.7566.905
14.9257.398
17.6488.471
18.6338.542
16.3288.169
18.1577.768
25.5838.06
27.8558.937
33.5758.99165
36.21178.74705
Global volume in 2014: 45.0 Million Liters
Source Plasma
Recovered Plasma
Source Plasma
Recovered Plasma
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION 1990 - 2014Recovered & Source in Liters
Population_2014
World Population 2014 (UN)
2014
Middle East/Africa1,13615.7%
North America3544.9%
Asia & Pacific4,39060.7%
South America6178.5%
Europe74110.2%
Total7,238100.0%
Population_2014
Source: PopulationReference Bureau
World Population by Region - 2014
Plasma_Supply_Regions
3/10/12
Liters of Plasma (1000 liters)
RecoveredSourceTotal
Asia & Pacific1,4616,2277,689
Middle East/ Africa32210042228
North America2,09026,48228,5716
Latin America44260502
Europe4,4333,3437,775
Total8,74736,21244,959
Ratio Recovered to Source PlasmaRatio Recovered to Source Plasma
RecoveredSourceRecovered+Source
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Plasma_Supply_Regions
Total recovered & source: 44,959,000 liters
Plasma for Fractionation by Region 2014(Recovered & Source)
Plasma_Supply_Country
3/10/12
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Australia325256581325256581
China *- 04,9504,950- 05,2005,200
India352- 0352352- 0352
Japan402554956402554956
Hong Kong3053530535
Korea (Rep)201210411201210411
Malaysia23- 02323- 023
New Zealand51- 05151- 051
Singapore82108210
Taiwan30- 03030- 030
Thailand30- 03030- 030
Other Asia10- 01010- 010
Sub-total Asia & Pacific1,4615,9777,4391,4616,2277,68917.1%
Argentina14051451405145
Brazil140- 0140140- 0140
Chile15- 01515- 015
Cuba1001511510015115
Mexico5- 055- 05
Uruguay12- 01212- 012
Venezuela204060204060
Other Latin America10- 01010- 010
Sub-total Latin America44260502442605021.1%
Canada24042432404243
United States *1,95024,15326,1031,85026,47828,328
Sub-total North America2,19024,15726,3462,09026,48228,57163.6%
South Africa *10051051005105
Iran1409523514095235
Egypt5- 055- 05
Morocco15- 01515- 015
Israel47- 04747- 047
Other Middle East/Africa15- 01515- 015
Sub-total Middle East/Africa3221004223221004220.9%
* 2014 Data
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Austria5056061050560610
Belgium179- 0179179- 0179
Bulgaria15- 01515- 015
Croatia25- 02525- 025
Czech Republic5045050050450500
Denmark60- 06060- 060
Finland60- 06060- 060
France6898477368984773271.41
Germany *1,2051,8503,0551,0201,7622,782
Greece5- 055- 05
Hungary81371188137118
Italy836- 0836836- 0836
Latvia10- 01010- 010
Lithuania12- 01212- 012
Macedonia5- 055- 05
Netherlands150150300150150300
Norway451055451055
Poland2602028026020280
Russia *110120230150270420
Serbia15- 01515- 015
Slovakia15- 01515- 015
Slovenia25- 02525- 025
Spain350- 0350350- 0350
Sweden145- 0145145- 0145
Switzerland80- 08080- 080
Ukraine70- 07070- 070
Other Europe30- 03030- 030
Sub-total Europe4,5773,2817,8584,4333,3437,77517.3%
World Total8,99233,57542,5678,74736,21244,959100.0%
- 019%81%100%
42,56744,959
RecoveredApheresisTotal
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Kg. x 1000Kg. x 1000
1,0641,124
741741
170.267179.835
141141
Total: 8,992,000 liters
Total recovered: 8,747,000 liters
Plasma for Fractionation by Region 2014(Recovered)
Total: 33,575,000 liters
Total source 36,212,000 liters
Plasma for Fractionation by Region 2014(Source)
Recovered
Source
Percentage Recovered & Source Plasma by Region - 2014
Charts_Plasma_Coll
Annual compounded growth rate (ACGR) from 1996 to 2012. Source plasma for fractionation0
Annual compounded growth rate (ACGR) from 1996 to 2012. Recovered plasma for fractionation0157,356
Annual compounded growth rate (ACGR) from 1996 to 2012. Total source & recovered plasma for fractionation01,123,969
COMMERCIAL & NON-PROFIT ORGANIZATIONS
(Thousand Liters)
GrowthGrowth
WORLD1990199319961999200220042007201020122013201410 years24 years
Source Plasma9.812.814.917.618.616.318.225.627.933.636.28.3%5.6%
Recovered Plasma6.66.97.48.58.58.27.88.18.99.08.70.7%1.2%
Total16.419.722.326.127.224.525.933.636.842.645.06.3%4.3%
Annual Growth Rate6.3%4.3%5.4%1.3%-5.1%1.9%9.1%4.6%7.6%10.5%
Source Plasma9,81712,75614,92517,64818,63316,32818,15725,58327,85533,57536,212
Recovered Plasma6,5636,9057,3988,4718,5428,1697,7688,0608,9378,9928,747
Total16,38019,66122,32326,11927,17524,49725,92533,64336,79242,56744,959
Increment (Liters x 000)3,2812,6623,7961,056-2,6781,4287,7183,1495,7752,392
Charts_Plasma_Coll
Global volume in 2014: 45.0 Million Liters
Source Plasma
Recovered Plasma
Source Plasma
Recovered Plasma
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION 1990 - 2014Recovered & Source in Liters
Charts_Fractionators
65 Plasma Fractionators worldwide
Europe 1515
Middle East/Africa 44
Latin America 44
Asia & Pacific 3838
North America 44
65
Plasma Throughput 42.6 million liters worldwide
Europe18,000
Middle East/Africa1,450
Asia & Pacific6,500
Latin America330
North America14,150
40,430
33000
0.82
Total volume in 2014: 45.0 Million Liters
Total
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION1990 - 2014Recovered & Source in Liters
Charts_Fractionators
TOTAL : 71 FRACTIONATION PLANTS
Total Number of Fractionation Plants: 65
REGIONAL DISTRIBUTION OF FRACTIONATION PLANTS 2014
IGG_Charts
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014North America69.746%
(Kilograms)RoW1.91%
Europe42.028%
Initial file, amended one table belowMiddle East3.72%
1992*1994*1996*19982000200320052008201020122014Asia & Pacific27.418%
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703Latin America7.05%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006100%
Asia & Pacific4,3284,4424,6645,2759,3839,6959,7968,48716,97618,21323,476
Latin America1782931,1386388751,6372,2172,8854,1034,5836,979
Middle East---6351,1931,6231,8451,7713,8253,8303,739
Oceania485686473181,0281,5281,7542,8182,9053,4393,908
Africa631183207335978129228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77685,151107,293122,332151,680
1992-1996-Asia and Mid-East together
Initial file, amended one table below
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014
(Kilograms)
1992*1994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,384
Latin America1782931,1386388751,6372,2172,8854,1044,5836,979
Middle East1002004006351,1931,6231,8451,7703,8253,8303,739
RoW631183207335978119228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,680
* Includes Oceania (Australia/NZ)
* Amended: Middle East has been carved out from Asia and Pacific (100 Kg. in 1992, 200 in 1994 and 400 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
19921994199619982000200320052008201020122014
9.914.517.617.119.727.031.643.151.459.469.7
5.27.811.111.914.615.820.725.226.230.942.0
4.34.84.95.610.411.211.611.319.921.727.4
0.20.31.10.60.91.62.22.94.14.67.0
0.10.20.40.61.21.61.81.83.83.83.7
0.10.10.30.70.60.80.90.91.91.91.9
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0
1992*1994*1996*19982000200320052008201020122014
North America9.914.517.617.119.727.031.643.151.459.469.7
Europe5.27.811.111.914.615.820.725.226.230.942.0
Asia & Pacific*4.34.84.95.610.411.211.611.319.921.727.4
RoW0.30.61.92.02.74.15.05.59.810.312.6
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
Annual
Growth rate
2005-2015
19921994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,7039.2%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,0068.2%
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,38410.1%
RoW3406101,8582,0052,6654,0724,9845,5419,84110,32812,58710.8%
Total (000)19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,6809.2%
0
Total (MM)19.727.735.536.647.458.268.885.2107.3122.3151.7
TOTAL : 71 FRACTIONATION PLANTS
Global Plasma Throughput 2014: 42.2 million liters
REGIONAL DISTRIBUTION OF FRACTIONATION THROUGHPUT 2014
IGG_Charts
* Includes Australia & New Zealand
North America
Europe
Asia & Pacific*
RoW
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION FROM 1992 TO 2014(Metric Tons)
Pharma_Mkt
IMS DataPharma market
Africa13,213,166,396
Asia major193,119,667,483
Central America11,201,994,793
Europe - Key Five211,585,009,569
Europe - Other105,953,031,494
Middle East5,505,595,391
North America403,418,901,401
South America67,665,782,195
Southeast Asia40,646,773,783
Total1,052,309,922,505
Africa & Middle East18,718,761,787
Asia & Pacific233,766,441,266
Latin America78,867,776,988
Europe317,538,041,063
North America403,418,901,401
Tally- 0
Africa & Middle East1.8%18,718,761,787
Asia & Pacific22.2%233,766,441,266
Latin America7.5%78,867,776,988
Europe30.2%317,538,041,063
North America38.3%403,418,901,401
Total100.0%- 0
MRB DataPlasma market
Latin America5.3%
North America41.6%
Africa & Middle East4.3%
Asia & Pacific20.9%
Europe27.9%
Total100.0%
0.2%
Total (MM)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION (Percentage of Metric Tons)Total: 151.7 Metric Tons
Pharma_Mkt
Total: 8,992,000 liters
Total market $1,052.3 Billion
The Global Pharmaceutical Market by Region 2014(Source: IMS)
Albumin_Chart
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.71176
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific121.9163.5162.0175.0176.2157.4157.5199.9237.8270.0412.4North America169.7
Latin America8.58.632.223.122.824.529.232.934.238.143.7Latin America43.7
Middle East---12.215.221.122.625.940.540.548.5Europe144.7
Oceania5.04.64.94.74.64.95.06.56.96.97.6Asia & Pacific420.0
Africa4.34.96.16.17.610.611.312.920.220.224.3Middle East/Africa72.8
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
1992-1996-Asia and Mid-East together
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific117.9157.5154.0175.0176.2157.4157.5199.9237.8270.0412.4
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East4.06.08.012.215.221.122.625.940.540.548.5
Oceania5.04.64.94.74.64.95.06.56.96.97.6
Africa4.34.96.16.17.610.611.312.920.220.224.3
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. in 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
Tally0.00.00.00.00.00.00.00.00.00.00.0
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific122.9162.1158.9179.7180.8162.3162.5206.4244.8276.9420.0
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East/Africa8.310.914.118.322.831.734.038.860.760.772.85.4%
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.96.9%
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. In 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand
Total: 8,992,000 liters
Total market $19.7 Billion
The Global Plasma Proteins Market by Region 2014(Source: MRB)
Albumin_Chart
North America
Europe
Asia & Pacific
Latin America
Middle East/Africa
WORLDWIDE ALBUMIN SALES BY REGION FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES BY REGION(Percentage of Metric Tons)Total: 850.9 Metric Tons
-
Europa stellt 10% der Weltbevlkerung dar und produziert 51% des weltweiten Recoverd-Plasma zur Fraktionierung
World Population by Region - 2014
South America8.5%
Asia & Pacific60.7%
Middle East/Africa15.7% North America
4.9%Europe10.2%
Source: PopulationReference Bureau
Plasma for Fractionation by Region 2014(Recovered)
Asia & Pacific16.7%
Middle East/ Africa3.7%
North America23.9%
Latin America5.0%
Europe50.7%
Total recovered: 8,747,000 liters
Chart5
1136
354
4390
617
741
Source: PopulationReference Bureau
World Population by Region - 2014
Population_2014
World Population 2014 (UN)
2014
Middle East/Africa1,13615.7%
North America3544.9%
Asia & Pacific4,39060.7%
South America6178.5%
Europe74110.2%
Total7,238100.0%
Population_2014
Source: PopulationReference Bureau
World Population by Region - 2014
Plasma_Supply_Regions
3/10/12
Liters of Plasma (1000 liters)
RecoveredSourceTotal
Asia & Pacific1,4616,2277,689
Middle East/ Africa32210042228
North America2,09026,48228,5716
Latin America44260502
Europe4,4333,3437,775
Total8,74736,21244,959
Ratio Recovered to Source PlasmaRatio Recovered to Source Plasma
RecoveredSourceRecovered+Source
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Plasma_Supply_Regions
Total recovered & source: 44,959,000 liters
Plasma for Fractionation by Region 2014(Recovered & Source)
Plasma_Supply_Country
3/10/12
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Australia325256581325256581
China *- 04,9504,950- 05,2005,200
India352- 0352352- 0352
Japan402554956402554956
Hong Kong3053530535
Korea (Rep)201210411201210411
Malaysia23- 02323- 023
New Zealand51- 05151- 051
Singapore82108210
Taiwan30- 03030- 030
Thailand30- 03030- 030
Other Asia10- 01010- 010
Sub-total Asia & Pacific1,4615,9777,4391,4616,2277,68917.1%
Argentina14051451405145
Brazil140- 0140140- 0140
Chile15- 01515- 015
Cuba1001511510015115
Mexico5- 055- 05
Uruguay12- 01212- 012
Venezuela204060204060
Other Latin America10- 01010- 010
Sub-total Latin America44260502442605021.1%
Canada24042432404243
United States *1,95024,15326,1031,85026,47828,328
Sub-total North America2,19024,15726,3462,09026,48228,57163.6%
South Africa *10051051005105
Iran1409523514095235
Egypt5- 055- 05
Morocco15- 01515- 015
Israel47- 04747- 047
Other Middle East/Africa15- 01515- 015
Sub-total Middle East/Africa3221004223221004220.9%
* 2014 Data
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Austria5056061050560610
Belgium179- 0179179- 0179
Bulgaria15- 01515- 015
Croatia25- 02525- 025
Czech Republic5045050050450500
Denmark60- 06060- 060
Finland60- 06060- 060
France6898477368984773271.41
Germany *1,2051,8503,0551,0201,7622,782
Greece5- 055- 05
Hungary81371188137118
Italy836- 0836836- 0836
Latvia10- 01010- 010
Lithuania12- 01212- 012
Macedonia5- 055- 05
Netherlands150150300150150300
Norway451055451055
Poland2602028026020280
Russia *110120230150270420
Serbia15- 01515- 015
Slovakia15- 01515- 015
Slovenia25- 02525- 025
Spain350- 0350350- 0350
Sweden145- 0145145- 0145
Switzerland80- 08080- 080
Ukraine70- 07070- 070
Other Europe30- 03030- 030
Sub-total Europe4,5773,2817,8584,4333,3437,77517.3%
World Total8,99233,57542,5678,74736,21244,959100.0%
- 019%81%100%
42,56744,959
RecoveredApheresisTotal
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Kg. x 1000Kg. x 1000
1,0641,124
741741
170.267179.835
141141
Total: 8,992,000 liters
Total recovered: 8,747,000 liters
Plasma for Fractionation by Region 2014(Recovered)
Total: 33,575,000 liters
Total source 36,212,000 liters
Plasma for Fractionation by Region 2014(Source)
Recovered
Source
Percentage Recovered & Source Plasma by Region - 2014
Charts_Plasma_Coll
Annual compounded growth rate (ACGR) from 1996 to 2012. Source plasma for fractionation0
Annual compounded growth rate (ACGR) from 1996 to 2012. Recovered plasma for fractionation0157,356
Annual compounded growth rate (ACGR) from 1996 to 2012. Total source & recovered plasma for fractionation01,123,969
COMMERCIAL & NON-PROFIT ORGANIZATIONS
(Thousand Liters)
GrowthGrowth
WORLD1990199319961999200220042007201020122013201410 years24 years
Source Plasma9.812.814.917.618.616.318.225.627.933.636.28.3%5.6%
Recovered Plasma6.66.97.48.58.58.27.88.18.99.08.70.7%1.2%
Total16.419.722.326.127.224.525.933.636.842.645.06.3%4.3%
Annual Growth Rate6.3%4.3%5.4%1.3%-5.1%1.9%9.1%4.6%7.6%10.5%
Source Plasma9,81712,75614,92517,64818,63316,32818,15725,58327,85533,57536,212
Recovered Plasma6,5636,9057,3988,4718,5428,1697,7688,0608,9378,9928,747
Total16,38019,66122,32326,11927,17524,49725,92533,64336,79242,56744,959
Increment (Liters x 000)3,2812,6623,7961,056-2,6781,4287,7183,1495,7752,392
Charts_Plasma_Coll
Global volume in 2014: 45.0 Million Liters
Source Plasma
Recovered Plasma
Source Plasma
Recovered Plasma
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION 1990 - 2014Recovered & Source in Liters
Charts_Fractionators
65 Plasma Fractionators worldwide
Europe 1515
Middle East/Africa 44
Latin America 44
Asia & Pacific 3838
North America 44
65
Plasma Throughput 42.6 million liters worldwide
Europe18,000
Middle East/Africa1,450
Asia & Pacific6,500
Latin America330
North America14,150
40,430
33000
0.82
Total volume in 2014: 45.0 Million Liters
Total
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION1990 - 2014Recovered & Source in Liters
Charts_Fractionators
TOTAL : 71 FRACTIONATION PLANTS
Total Number of Fractionation Plants: 65
REGIONAL DISTRIBUTION OF FRACTIONATION PLANTS 2014
IGG_Charts
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014North America69.746%
(Kilograms)RoW1.91%
Europe42.028%
Initial file, amended one table belowMiddle East3.72%
1992*1994*1996*19982000200320052008201020122014Asia & Pacific27.418%
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703Latin America7.05%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006100%
Asia & Pacific4,3284,4424,6645,2759,3839,6959,7968,48716,97618,21323,476
Latin America1782931,1386388751,6372,2172,8854,1034,5836,979
Middle East---6351,1931,6231,8451,7713,8253,8303,739
Oceania485686473181,0281,5281,7542,8182,9053,4393,908
Africa631183207335978129228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77685,151107,293122,332151,680
1992-1996-Asia and Mid-East together
Initial file, amended one table below
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014
(Kilograms)
1992*1994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,384
Latin America1782931,1386388751,6372,2172,8854,1044,5836,979
Middle East1002004006351,1931,6231,8451,7703,8253,8303,739
RoW631183207335978119228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,680
* Includes Oceania (Australia/NZ)
* Amended: Middle East has been carved out from Asia and Pacific (100 Kg. in 1992, 200 in 1994 and 400 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
19921994199619982000200320052008201020122014
9.914.517.617.119.727.031.643.151.459.469.7
5.27.811.111.914.615.820.725.226.230.942.0
4.34.84.95.610.411.211.611.319.921.727.4
0.20.31.10.60.91.62.22.94.14.67.0
0.10.20.40.61.21.61.81.83.83.83.7
0.10.10.30.70.60.80.90.91.91.91.9
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0
1992*1994*1996*19982000200320052008201020122014
North America9.914.517.617.119.727.031.643.151.459.469.7
Europe5.27.811.111.914.615.820.725.226.230.942.0
Asia & Pacific*4.34.84.95.610.411.211.611.319.921.727.4
RoW0.30.61.92.02.74.15.05.59.810.312.6
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
Annual
Growth rate
2005-2015
19921994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,7039.2%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,0068.2%
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,38410.1%
RoW3406101,8582,0052,6654,0724,9845,5419,84110,32812,58710.8%
Total (000)19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,6809.2%
0
Total (MM)19.727.735.536.647.458.268.885.2107.3122.3151.7
TOTAL : 71 FRACTIONATION PLANTS
Global Plasma Throughput 2014: 42.2 million liters
REGIONAL DISTRIBUTION OF FRACTIONATION THROUGHPUT 2014
IGG_Charts
* Includes Australia & New Zealand
North America
Europe
Asia & Pacific*
RoW
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION FROM 1992 TO 2014(Metric Tons)
Pharma_Mkt
IMS DataPharma market
Africa13,213,166,396
Asia major193,119,667,483
Central America11,201,994,793
Europe - Key Five211,585,009,569
Europe - Other105,953,031,494
Middle East5,505,595,391
North America403,418,901,401
South America67,665,782,195
Southeast Asia40,646,773,783
Total1,052,309,922,505
Africa & Middle East18,718,761,787
Asia & Pacific233,766,441,266
Latin America78,867,776,988
Europe317,538,041,063
North America403,418,901,401
Tally- 0
Africa & Middle East1.8%18,718,761,787
Asia & Pacific22.2%233,766,441,266
Latin America7.5%78,867,776,988
Europe30.2%317,538,041,063
North America38.3%403,418,901,401
Total100.0%- 0
MRB DataPlasma market
Latin America5.3%
North America41.6%
Africa & Middle East4.3%
Asia & Pacific20.9%
Europe27.9%
Total100.0%
0.2%
Total (MM)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION (Percentage of Metric Tons)Total: 151.7 Metric Tons
Pharma_Mkt
Total: 8,992,000 liters
Total market $1,052.3 Billion
The Global Pharmaceutical Market by Region 2014(Source: IMS)
Albumin_Chart
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.71176
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific121.9163.5162.0175.0176.2157.4157.5199.9237.8270.0412.4North America169.7
Latin America8.58.632.223.122.824.529.232.934.238.143.7Latin America43.7
Middle East---12.215.221.122.625.940.540.548.5Europe144.7
Oceania5.04.64.94.74.64.95.06.56.96.97.6Asia & Pacific420.0
Africa4.34.96.16.17.610.611.312.920.220.224.3Middle East/Africa72.8
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
1992-1996-Asia and Mid-East together
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific117.9157.5154.0175.0176.2157.4157.5199.9237.8270.0412.4
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East4.06.08.012.215.221.122.625.940.540.548.5
Oceania5.04.64.94.74.64.95.06.56.96.97.6
Africa4.34.96.16.17.610.611.312.920.220.224.3
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. in 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
Tally0.00.00.00.00.00.00.00.00.00.00.0
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific122.9162.1158.9179.7180.8162.3162.5206.4244.8276.9420.0
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East/Africa8.310.914.118.322.831.734.038.860.760.772.85.4%
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.96.9%
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. In 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand
Total: 8,992,000 liters
Total market $19.7 Billion
The Global Plasma Proteins Market by Region 2014(Source: MRB)
Albumin_Chart
North America
Europe
Asia & Pacific
Latin America
Middle East/Africa
WORLDWIDE ALBUMIN SALES BY REGION FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES BY REGION(Percentage of Metric Tons)Total: 850.9 Metric Tons
Chart4
1461.4
322
2089.6
441.55
4432.5
Total: 8,992,000 liters
Total recovered: 8,747,000 liters
Plasma for Fractionation by Region 2014(Recovered)
Population_2014
World Population 2014 (UN)
2014
Middle East/Africa1,13615.7%
North America3544.9%
Asia & Pacific4,39060.7%
South America6178.5%
Europe74110.2%
Total7,238100.0%
Population_2014
Source: PopulationReference Bureau
World Population by Region - 2014
Plasma_Supply_Regions
3/10/12
Liters of Plasma (1000 liters)
RecoveredSourceTotal
Asia & Pacific1,4616,2277,689
Middle East/ Africa32210042228
North America2,09026,48228,5716
Latin America44260502
Europe4,4333,3437,775
Total8,74736,21244,959
Ratio Recovered to Source PlasmaRatio Recovered to Source Plasma
RecoveredSourceRecovered+Source
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Plasma_Supply_Regions
Total recovered & source: 44,959,000 liters
Plasma for Fractionation by Region 2014(Recovered & Source)
Plasma_Supply_Country
3/10/12
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Australia325256581325256581
China *- 04,9504,950- 05,2005,200
India352- 0352352- 0352
Japan402554956402554956
Hong Kong3053530535
Korea (Rep)201210411201210411
Malaysia23- 02323- 023
New Zealand51- 05151- 051
Singapore82108210
Taiwan30- 03030- 030
Thailand30- 03030- 030
Other Asia10- 01010- 010
Sub-total Asia & Pacific1,4615,9777,4391,4616,2277,68917.1%
Argentina14051451405145
Brazil140- 0140140- 0140
Chile15- 01515- 015
Cuba1001511510015115
Mexico5- 055- 05
Uruguay12- 01212- 012
Venezuela204060204060
Other Latin America10- 01010- 010
Sub-total Latin America44260502442605021.1%
Canada24042432404243
United States *1,95024,15326,1031,85026,47828,328
Sub-total North America2,19024,15726,3462,09026,48228,57163.6%
South Africa *10051051005105
Iran1409523514095235
Egypt5- 055- 05
Morocco15- 01515- 015
Israel47- 04747- 047
Other Middle East/Africa15- 01515- 015
Sub-total Middle East/Africa3221004223221004220.9%
* 2014 Data
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Austria5056061050560610
Belgium179- 0179179- 0179
Bulgaria15- 01515- 015
Croatia25- 02525- 025
Czech Republic5045050050450500
Denmark60- 06060- 060
Finland60- 06060- 060
France6898477368984773271.41
Germany *1,2051,8503,0551,0201,7622,782
Greece5- 055- 05
Hungary81371188137118
Italy836- 0836836- 0836
Latvia10- 01010- 010
Lithuania12- 01212- 012
Macedonia5- 055- 05
Netherlands150150300150150300
Norway451055451055
Poland2602028026020280
Russia *110120230150270420
Serbia15- 01515- 015
Slovakia15- 01515- 015
Slovenia25- 02525- 025
Spain350- 0350350- 0350
Sweden145- 0145145- 0145
Switzerland80- 08080- 080
Ukraine70- 07070- 070
Other Europe30- 03030- 030
Sub-total Europe4,5773,2817,8584,4333,3437,77517.3%
World Total8,99233,57542,5678,74736,21244,959100.0%
- 019%81%100%
42,56744,959
RecoveredApheresisTotal
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Kg. x 1000Kg. x 1000
1,0641,124
741741
170.267179.835
141141
Total: 8,992,000 liters
Total recovered: 8,747,000 liters
Plasma for Fractionation by Region 2014(Recovered)
Total: 33,575,000 liters
Total source 36,212,000 liters
Plasma for Fractionation by Region 2014(Source)
Recovered
Source
Percentage Recovered & Source Plasma by Region - 2014
Charts_Plasma_Coll
Annual compounded growth rate (ACGR) from 1996 to 2012. Source plasma for fractionation0
Annual compounded growth rate (ACGR) from 1996 to 2012. Recovered plasma for fractionation0157,356
Annual compounded growth rate (ACGR) from 1996 to 2012. Total source & recovered plasma for fractionation01,123,969
COMMERCIAL & NON-PROFIT ORGANIZATIONS
(Thousand Liters)
GrowthGrowth
WORLD1990199319961999200220042007201020122013201410 years24 years
Source Plasma9.812.814.917.618.616.318.225.627.933.636.28.3%5.6%
Recovered Plasma6.66.97.48.58.58.27.88.18.99.08.70.7%1.2%
Total16.419.722.326.127.224.525.933.636.842.645.06.3%4.3%
Annual Growth Rate6.3%4.3%5.4%1.3%-5.1%1.9%9.1%4.6%7.6%10.5%
Source Plasma9,81712,75614,92517,64818,63316,32818,15725,58327,85533,57536,212
Recovered Plasma6,5636,9057,3988,4718,5428,1697,7688,0608,9378,9928,747
Total16,38019,66122,32326,11927,17524,49725,92533,64336,79242,56744,959
Increment (Liters x 000)3,2812,6623,7961,056-2,6781,4287,7183,1495,7752,392
Charts_Plasma_Coll
Global volume in 2014: 45.0 Million Liters
Source Plasma
Recovered Plasma
Source Plasma
Recovered Plasma
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION 1990 - 2014Recovered & Source in Liters
Charts_Fractionators
65 Plasma Fractionators worldwide
Europe 1515
Middle East/Africa 44
Latin America 44
Asia & Pacific 3838
North America 44
65
Plasma Throughput 42.6 million liters worldwide
Europe18,000
Middle East/Africa1,450
Asia & Pacific6,500
Latin America330
North America14,150
40,430
33000
0.82
Total volume in 2014: 45.0 Million Liters
Total
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION1990 - 2014Recovered & Source in Liters
Charts_Fractionators
TOTAL : 71 FRACTIONATION PLANTS
Total Number of Fractionation Plants: 65
REGIONAL DISTRIBUTION OF FRACTIONATION PLANTS 2014
IGG_Charts
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014North America69.746%
(Kilograms)RoW1.91%
Europe42.028%
Initial file, amended one table belowMiddle East3.72%
1992*1994*1996*19982000200320052008201020122014Asia & Pacific27.418%
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703Latin America7.05%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006100%
Asia & Pacific4,3284,4424,6645,2759,3839,6959,7968,48716,97618,21323,476
Latin America1782931,1386388751,6372,2172,8854,1034,5836,979
Middle East---6351,1931,6231,8451,7713,8253,8303,739
Oceania485686473181,0281,5281,7542,8182,9053,4393,908
Africa631183207335978129228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77685,151107,293122,332151,680
1992-1996-Asia and Mid-East together
Initial file, amended one table below
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014
(Kilograms)
1992*1994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,384
Latin America1782931,1386388751,6372,2172,8854,1044,5836,979
Middle East1002004006351,1931,6231,8451,7703,8253,8303,739
RoW631183207335978119228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,680
* Includes Oceania (Australia/NZ)
* Amended: Middle East has been carved out from Asia and Pacific (100 Kg. in 1992, 200 in 1994 and 400 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
19921994199619982000200320052008201020122014
9.914.517.617.119.727.031.643.151.459.469.7
5.27.811.111.914.615.820.725.226.230.942.0
4.34.84.95.610.411.211.611.319.921.727.4
0.20.31.10.60.91.62.22.94.14.67.0
0.10.20.40.61.21.61.81.83.83.83.7
0.10.10.30.70.60.80.90.91.91.91.9
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0
1992*1994*1996*19982000200320052008201020122014
North America9.914.517.617.119.727.031.643.151.459.469.7
Europe5.27.811.111.914.615.820.725.226.230.942.0
Asia & Pacific*4.34.84.95.610.411.211.611.319.921.727.4
RoW0.30.61.92.02.74.15.05.59.810.312.6
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
Annual
Growth rate
2005-2015
19921994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,7039.2%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,0068.2%
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,38410.1%
RoW3406101,8582,0052,6654,0724,9845,5419,84110,32812,58710.8%
Total (000)19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,6809.2%
0
Total (MM)19.727.735.536.647.458.268.885.2107.3122.3151.7
TOTAL : 71 FRACTIONATION PLANTS
Global Plasma Throughput 2014: 42.2 million liters
REGIONAL DISTRIBUTION OF FRACTIONATION THROUGHPUT 2014
IGG_Charts
* Includes Australia & New Zealand
North America
Europe
Asia & Pacific*
RoW
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION FROM 1992 TO 2014(Metric Tons)
Pharma_Mkt
IMS DataPharma market
Africa13,213,166,396
Asia major193,119,667,483
Central America11,201,994,793
Europe - Key Five211,585,009,569
Europe - Other105,953,031,494
Middle East5,505,595,391
North America403,418,901,401
South America67,665,782,195
Southeast Asia40,646,773,783
Total1,052,309,922,505
Africa & Middle East18,718,761,787
Asia & Pacific233,766,441,266
Latin America78,867,776,988
Europe317,538,041,063
North America403,418,901,401
Tally- 0
Africa & Middle East1.8%18,718,761,787
Asia & Pacific22.2%233,766,441,266
Latin America7.5%78,867,776,988
Europe30.2%317,538,041,063
North America38.3%403,418,901,401
Total100.0%- 0
MRB DataPlasma market
Latin America5.3%
North America41.6%
Africa & Middle East4.3%
Asia & Pacific20.9%
Europe27.9%
Total100.0%
0.2%
Total (MM)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION (Percentage of Metric Tons)Total: 151.7 Metric Tons
Pharma_Mkt
Total: 8,992,000 liters
Total market $1,052.3 Billion
The Global Pharmaceutical Market by Region 2014(Source: IMS)
Albumin_Chart
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.71176
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific121.9163.5162.0175.0176.2157.4157.5199.9237.8270.0412.4North America169.7
Latin America8.58.632.223.122.824.529.232.934.238.143.7Latin America43.7
Middle East---12.215.221.122.625.940.540.548.5Europe144.7
Oceania5.04.64.94.74.64.95.06.56.96.97.6Asia & Pacific420.0
Africa4.34.96.16.17.610.611.312.920.220.224.3Middle East/Africa72.8
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
1992-1996-Asia and Mid-East together
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific117.9157.5154.0175.0176.2157.4157.5199.9237.8270.0412.4
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East4.06.08.012.215.221.122.625.940.540.548.5
Oceania5.04.64.94.74.64.95.06.56.96.97.6
Africa4.34.96.16.17.610.611.312.920.220.224.3
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. in 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
Tally0.00.00.00.00.00.00.00.00.00.00.0
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific122.9162.1158.9179.7180.8162.3162.5206.4244.8276.9420.0
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East/Africa8.310.914.118.322.831.734.038.860.760.772.85.4%
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.96.9%
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. In 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand
Total: 8,992,000 liters
Total market $19.7 Billion
The Global Plasma Proteins Market by Region 2014(Source: MRB)
Albumin_Chart
North America
Europe
Asia & Pacific
Latin America
Middle East/Africa
WORLDWIDE ALBUMIN SALES BY REGION FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES BY REGION(Percentage of Metric Tons)Total: 850.9 Metric Tons
-
Nordamerika betrgt 5% der Weltbevlkerung und produziert 73% des weltweiten Source-Plasma zur Fraktionierung
World Population by Region - 2014
South America8.5%
Asia & Pacific60.7%
Middle East/Africa15.7% North America
4.9%Europe10.2%
Source: PopulationReference Bureau
Plasma for Fractionation by Region 2014(Source)
North America73.1%
Asia & Pacific17.2%
Latin America0.2%
Europe9.2%
Middle East/ Africa0.3%
Total source 36,212,000 liters
Chart4
1136
354
4390
617
741
Source: PopulationReference Bureau
World Population by Region - 2014
Population_2014
World Population 2014 (UN)
2014
Middle East/Africa1,13615.7%
North America3544.9%
Asia & Pacific4,39060.7%
South America6178.5%
Europe74110.2%
Total7,238100.0%
Population_2014
Source: PopulationReference Bureau
World Population by Region - 2014
Plasma_Supply_Regions
3/10/12
Liters of Plasma (1000 liters)
RecoveredSourceTotal
Asia & Pacific1,4616,2277,689
Middle East/ Africa32210042228
North America2,09026,48228,5716
Latin America44260502
Europe4,4333,3437,775
Total8,74736,21244,959
Ratio Recovered to Source PlasmaRatio Recovered to Source Plasma
RecoveredSourceRecovered+Source
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Plasma_Supply_Regions
Total recovered & source: 44,959,000 liters
Plasma for Fractionation by Region 2014(Recovered & Source)
Plasma_Supply_Country
3/10/12
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Australia325256581325256581
China *- 04,9504,950- 05,2005,200
India352- 0352352- 0352
Japan402554956402554956
Hong Kong3053530535
Korea (Rep)201210411201210411
Malaysia23- 02323- 023
New Zealand51- 05151- 051
Singapore82108210
Taiwan30- 03030- 030
Thailand30- 03030- 030
Other Asia10- 01010- 010
Sub-total Asia & Pacific1,4615,9777,4391,4616,2277,68917.1%
Argentina14051451405145
Brazil140- 0140140- 0140
Chile15- 01515- 015
Cuba1001511510015115
Mexico5- 055- 05
Uruguay12- 01212- 012
Venezuela204060204060
Other Latin America10- 01010- 010
Sub-total Latin America44260502442605021.1%
Canada24042432404243
United States *1,95024,15326,1031,85026,47828,328
Sub-total North America2,19024,15726,3462,09026,48228,57163.6%
South Africa *10051051005105
Iran1409523514095235
Egypt5- 055- 05
Morocco15- 01515- 015
Israel47- 04747- 047
Other Middle East/Africa15- 01515- 015
Sub-total Middle East/Africa3221004223221004220.9%
* 2014 Data
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Austria5056061050560610
Belgium179- 0179179- 0179
Bulgaria15- 01515- 015
Croatia25- 02525- 025
Czech Republic5045050050450500
Denmark60- 06060- 060
Finland60- 06060- 060
France6898477368984773271.41
Germany *1,2051,8503,0551,0201,7622,782
Greece5- 055- 05
Hungary81371188137118
Italy836- 0836836- 0836
Latvia10- 01010- 010
Lithuania12- 01212- 012
Macedonia5- 055- 05
Netherlands150150300150150300
Norway451055451055
Poland2602028026020280
Russia *110120230150270420
Serbia15- 01515- 015
Slovakia15- 01515- 015
Slovenia25- 02525- 025
Spain350- 0350350- 0350
Sweden145- 0145145- 0145
Switzerland80- 08080- 080
Ukraine70- 07070- 070
Other Europe30- 03030- 030
Sub-total Europe4,5773,2817,8584,4333,3437,77517.3%
World Total8,99233,57542,5678,74736,21244,959100.0%
- 019%81%100%
42,56744,959
RecoveredApheresisTotal
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Kg. x 1000Kg. x 1000
1,0641,124
741741
170.267179.835
141141
Total: 8,992,000 liters
Total recovered: 8,747,000 liters
Plasma for Fractionation by Region 2014(Recovered)
Total: 33,575,000 liters
Total source 36,212,000 liters
Plasma for Fractionation by Region 2014(Source)
Recovered
Source
Percentage Recovered & Source Plasma by Region - 2014
Charts_Plasma_Coll
Annual compounded growth rate (ACGR) from 1996 to 2012. Source plasma for fractionation0
Annual compounded growth rate (ACGR) from 1996 to 2012. Recovered plasma for fractionation0157,356
Annual compounded growth rate (ACGR) from 1996 to 2012. Total source & recovered plasma for fractionation01,123,969
COMMERCIAL & NON-PROFIT ORGANIZATIONS
(Thousand Liters)
GrowthGrowth
WORLD1990199319961999200220042007201020122013201410 years24 years
Source Plasma9.812.814.917.618.616.318.225.627.933.636.28.3%5.6%
Recovered Plasma6.66.97.48.58.58.27.88.18.99.08.70.7%1.2%
Total16.419.722.326.127.224.525.933.636.842.645.06.3%4.3%
Annual Growth Rate6.3%4.3%5.4%1.3%-5.1%1.9%9.1%4.6%7.6%10.5%
Source Plasma9,81712,75614,92517,64818,63316,32818,15725,58327,85533,57536,212
Recovered Plasma6,5636,9057,3988,4718,5428,1697,7688,0608,9378,9928,747
Total16,38019,66122,32326,11927,17524,49725,92533,64336,79242,56744,959
Increment (Liters x 000)3,2812,6623,7961,056-2,6781,4287,7183,1495,7752,392
Charts_Plasma_Coll
Global volume in 2014: 45.0 Million Liters
Source Plasma
Recovered Plasma
Source Plasma
Recovered Plasma
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION 1990 - 2014Recovered & Source in Liters
Charts_Fractionators
65 Plasma Fractionators worldwide
Europe 1515
Middle East/Africa 44
Latin America 44
Asia & Pacific 3838
North America 44
65
Plasma Throughput 42.6 million liters worldwide
Europe18,000
Middle East/Africa1,450
Asia & Pacific6,500
Latin America330
North America14,150
40,430
33000
0.82
Total volume in 2014: 45.0 Million Liters
Total
GLOBAL VOLUME OF PLASMA FOR FRACTIONATION1990 - 2014Recovered & Source in Liters
Charts_Fractionators
TOTAL : 71 FRACTIONATION PLANTS
Total Number of Fractionation Plants: 65
REGIONAL DISTRIBUTION OF FRACTIONATION PLANTS 2014
IGG_Charts
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014North America69.746%
(Kilograms)RoW1.91%
Europe42.028%
Initial file, amended one table belowMiddle East3.72%
1992*1994*1996*19982000200320052008201020122014Asia & Pacific27.418%
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703Latin America7.05%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006100%
Asia & Pacific4,3284,4424,6645,2759,3839,6959,7968,48716,97618,21323,476
Latin America1782931,1386388751,6372,2172,8854,1034,5836,979
Middle East---6351,1931,6231,8451,7713,8253,8303,739
Oceania485686473181,0281,5281,7542,8182,9053,4393,908
Africa631183207335978129228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77685,151107,293122,332151,680
1992-1996-Asia and Mid-East together
Initial file, amended one table below
WORLDWIDE POLYVALENT INTRAVENOUS AND SUBCUTANEOUS IMMUNE GLOBULIN SALES FROM 1992 TO 2014
(Kilograms)
1992*1994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,703
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,006
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,384
Latin America1782931,1386388751,6372,2172,8854,1044,5836,979
Middle East1002004006351,1931,6231,8451,7703,8253,8303,739
RoW631183207335978119228851,9131,9151,869
Total19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,680
* Includes Oceania (Australia/NZ)
* Amended: Middle East has been carved out from Asia and Pacific (100 Kg. in 1992, 200 in 1994 and 400 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
19921994199619982000200320052008201020122014
9.914.517.617.119.727.031.643.151.459.469.7
5.27.811.111.914.615.820.725.226.230.942.0
4.34.84.95.610.411.211.611.319.921.727.4
0.20.31.10.60.91.62.22.94.14.67.0
0.10.20.40.61.21.61.81.83.83.83.7
0.10.10.30.70.60.80.90.91.91.91.9
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0- 0
1992*1994*1996*19982000200320052008201020122014
North America9.914.517.617.119.727.031.643.151.459.469.7
Europe5.27.811.111.914.615.820.725.226.230.942.0
Asia & Pacific*4.34.84.95.610.411.211.611.319.921.727.4
RoW0.30.61.92.02.74.15.05.59.810.312.6
Total19.727.735.536.647.458.268.885.2107.3122.3151.7
Annual
Growth rate
2005-2015
19921994*1996*19982000200320052008201020122014
North America9,91514,51517,59317,11019,68027,02531,57943,13551,42059,44069,7039.2%
Europe5,2057,80211,13011,93814,64315,83120,66425,17026,15230,91242,0068.2%
Asia & Pacific*4,2764,8104,9115,59310,41111,22311,55011,30519,88121,65227,38410.1%
RoW3406101,8582,0052,6654,0724,9845,5419,84110,32812,58710.8%
Total (000)19,73627,73735,49236,64547,39958,15068,77785,150107,294122,332151,6809.2%
0
Total (MM)19.727.735.536.647.458.268.885.2107.3122.3151.7
TOTAL : 71 FRACTIONATION PLANTS
Global Plasma Throughput 2014: 42.2 million liters
REGIONAL DISTRIBUTION OF FRACTIONATION THROUGHPUT 2014
IGG_Charts
* Includes Australia & New Zealand
North America
Europe
Asia & Pacific*
RoW
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION FROM 1992 TO 2014(Metric Tons)
Pharma_Mkt
IMS DataPharma market
Africa13,213,166,396
Asia major193,119,667,483
Central America11,201,994,793
Europe - Key Five211,585,009,569
Europe - Other105,953,031,494
Middle East5,505,595,391
North America403,418,901,401
South America67,665,782,195
Southeast Asia40,646,773,783
Total1,052,309,922,505
Africa & Middle East18,718,761,787
Asia & Pacific233,766,441,266
Latin America78,867,776,988
Europe317,538,041,063
North America403,418,901,401
Tally- 0
Africa & Middle East1.8%18,718,761,787
Asia & Pacific22.2%233,766,441,266
Latin America7.5%78,867,776,988
Europe30.2%317,538,041,063
North America38.3%403,418,901,401
Total100.0%- 0
MRB DataPlasma market
Latin America5.3%
North America41.6%
Africa & Middle East4.3%
Asia & Pacific20.9%
Europe27.9%
Total100.0%
0.2%
Total (MM)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE POLYVALENT IMMUNE GLOBULIN (IVIG/SCIG) SALES BY REGION (Percentage of Metric Tons)Total: 151.7 Metric Tons
Pharma_Mkt
Total: 8,992,000 liters
Total market $1,052.3 Billion
The Global Pharmaceutical Market by Region 2014(Source: IMS)
Albumin_Chart
2/17/12
Worldwide - Kilograms of IGIV (Polyvalent)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.71176
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific121.9163.5162.0175.0176.2157.4157.5199.9237.8270.0412.4North America169.7
Latin America8.58.632.223.122.824.529.232.934.238.143.7Latin America43.7
Middle East---12.215.221.122.625.940.540.548.5Europe144.7
Oceania5.04.64.94.74.64.95.06.56.96.97.6Asia & Pacific420.0
Africa4.34.96.16.17.610.611.312.920.220.224.3Middle East/Africa72.8
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
1992-1996-Asia and Mid-East together
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific117.9157.5154.0175.0176.2157.4157.5199.9237.8270.0412.4
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East4.06.08.012.215.221.122.625.940.540.548.5
Oceania5.04.64.94.74.64.95.06.56.96.97.6
Africa4.34.96.16.17.610.611.312.920.220.224.3
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.9
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. in 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand)
Tally0.00.00.00.00.00.00.00.00.00.00.0
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014
(Metric Tons)
19921994199619982000200320052008201020122014
North America126.5109.3119.0105.079.3121.6125.2125.5139.0152.8169.7
Europe148.2148.7131.1101.0100.2107.6116.2126.6128.6136.8144.7
Asia & Pacific122.9162.1158.9179.7180.8162.3162.5206.4244.8276.9420.0
Latin America8.58.632.223.122.824.529.232.934.238.143.7
Middle East/Africa8.310.914.118.322.831.734.038.860.760.772.85.4%
Total414.4439.6455.3427.2405.9447.7467.1530.3607.2665.3850.96.9%
* Amended: Middle East has been carved out from Asia and Pacific (4 Kg. In 1992, 6 in 1994 and 8 in 1996)
Asia and Pacific includes Oceania (Australia and New Zealand
Total: 8,992,000 liters
Total market $19.7 Billion
The Global Plasma Proteins Market by Region 2014(Source: MRB)
Albumin_Chart
North America
Europe
Asia & Pacific
Latin America
Middle East/Africa
WORLDWIDE ALBUMIN SALES BY REGION FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES FROM 1992 TO 2014(Metric Tons)
WORLDWIDE ALBUMIN SALES BY REGION(Percentage of Metric Tons)Total: 850.9 Metric Tons
Chart3
6227.2
100
26481.8
60
3342.7
Total: 33,575,000 liters
Total source 36,212,000 liters
Plasma for Fractionation by Region 2014(Source)
Population_2014
World Population 2014 (UN)
2014
Middle East/Africa1,13615.7%
North America3544.9%
Asia & Pacific4,39060.7%
South America6178.5%
Europe74110.2%
Total7,238100.0%
Population_2014
Source: PopulationReference Bureau
World Population by Region - 2014
Plasma_Supply_Regions
3/10/12
Liters of Plasma (1000 liters)
RecoveredSourceTotal
Asia & Pacific1,4616,2277,689
Middle East/ Africa32210042228
North America2,09026,48228,5716
Latin America44260502
Europe4,4333,3437,775
Total8,74736,21244,959
Ratio Recovered to Source PlasmaRatio Recovered to Source Plasma
RecoveredSourceRecovered+Source
Asia & Pacific19%81%100%
Middle East & Africa76%24%100%
North America7%93%100%
Latin America88%12%100%
Europe57%43%100%
World19%81%100%
Plasma_Supply_Regions
Total recovered & source: 44,959,000 liters
Plasma for Fractionation by Region 2014(Recovered & Source)
Plasma_Supply_Country
3/10/12
20132014
RecoveredApheresisTotalRecoveredApheresisTotal
Australia325256581325256581
China *- 04,9504,950- 05,2005,200
India352- 0352352- 0352
Japan402554956402554956
Hong Kong3053530535
Korea (Rep)201210411201210411
Malaysia23- 02323- 023
New Zealand51- 05151- 051
Singapore82108210
Taiwan30- 03030- 030
Thailand30- 03030- 030
Other Asia10- 01010- 010
Sub-total Asia & Pacific1,4615,9777,4391,4616,2277,68917.1%
Argentina14051451405145
Brazil140- 0140140- 0140
Chile15- 01515- 015
Cuba1001511510015115
Mexico5- 055- 05
Uruguay12- 01212- 012
Venezuela204060204060
Other Latin America10- 01010- 010
Sub-total Latin America44260502442605021.1%
Canada24042432404243
United States *1,95024,15326,1031,85026,47828,328
Sub-total North America2,19024,15726,3462,09026,48228,57163.6%
South Africa *10051051005105
Iran1409523514095235
Egypt5- 055- 05
Morocco15- 01515- 015
Israel47- 04747- 047
Other Middle East/Africa15- 01515- 015
Sub-total Middle East/Africa3221004223221004220.9%
* 2014 Data