Panacea or Pandora's Box? The $1,000 Genome is Here - Now What Do We Do?
Pandora's Box Final
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Transcript of Pandora's Box Final
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PANDORAS BOX
Let us start with a story ..
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Greek mythology
Zeus, Greek God, took back firefrom humans
Prometheus stole fire from heaven
Zeus took vengeance by presenting
Pandora to Epimetheus,Prometheus' brother.
With her, Pandora was given a
beautiful container.
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WHY ABDOMENA
PANDORAS BOX?one never knows what will come
out of it when one opens it.
WE EXPECT ONE THING MANYTIMES UNEXPECTED THINGCOMES OUT
WE EXPECT ONE THING NOTHING COMES OUT
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Case 1
60 year old female
Pain lower abdomen 4 days
Generalised 3 daysAbdominal distension 3 days
Vomiting 3 days
Obstipation 3 days History of bleeding PR on and off
No previous pain abdomen or surgery
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On examination
Lower abdominal distension
Tenderness lower abdominal
No obliteration of liver dullnessBowel sounds sluggish
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X-ray abdomen
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Usg abdomen
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What we expected ?
Serial examination
Distension and pain persisted
No bowel movements bowel sounds
absentDecision taken to do laparotomy
Intestinal obstruction -Malignancy
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What we found?
Duodenal perforation with peritonitis
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Case 2
44 year old female
Pain abdomen 5 Days
Abdominal distension 5 days
Vomiting 2 Days
PREVIOUS LAPAROTOMY FORHYSTERECTOMY
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Examination
Generalised abdominal distension
Tenderness
Bowel sounds exaggerated
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X-ray abdomen
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USG abdomen
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What we expected ?
Failed conservative management
Planned for laparotomy
Intestinal obstruction adhesions
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Intra-operative findingsGrowth in ascending colon
Right hemicolectomy done
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Case 3
37 year old female
Complains of pain abdomen rightiliac fossa 5 days
Fever
Vomiting
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On examination
Obese female
Abdominal distension
Maximum Tenderness mainly inright iliac fossa
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Diagnosis
Perforated appendix with abscessformation
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Investigations
Xray no specific findings
Usg collection in RIF
S. amylase normal
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Per-op findings
Pus collection in RIF but appendixnormal
pus appearing to come from upper
abdomen
Necrotizing pancreatitis
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Postop CT scan
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Case 4 and 5
25 year old male
Fever 7 days
Pain abdomen 4 Days
Vomiting - 2 Days
12 Year old male
Pain abdomen 5 daysDistension
Vomiting
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Examination
Features of peritonitis
USG free fluid present
TLC raisedX-ray abdomen no positive
finding
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Intra-operative findings
Normal appearing contents
Straw colored peritoneal fluid nopus
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Case 6
6 yr old girl case of RTAdiagnosed to have grade II splenicinjury with hemoperitoneum
Hemodynamically stable
Persisting abdominal distensionand pain
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Examination ( serial )
Abdominal distension
No features of peritonitis
Bowel sounds absent
X-ray abdomen no free air under
diaphragmUSG free fluid in abdomen
Dilated bowel loops
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Intra-operative findings-
jejunal perforation ( Day 3 )
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Case 7
50 year old female
Deaf and mute
Brought with c/o abdominaldistension and vomiting 5 days
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On examination
Abdominal distension
No features of peritonitis
Per rectal impacted stools
Enema stool passeddistensionslightly reduced
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Investigation
X-ray abdomen air fluid levels insmall bowel
Usg no significant findings other
than dilated bowel loops
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Diagnosis
Intestinal obstruction
However passes still c/o painabdomen
Examination guarding in rightiliac fossa
USG repeat- Collection in RIF
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Gangrenous appendix with
pus
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Why diagnosis is difficult ?
History may not be forthcoming/not reliable
Delayed presentation
Atypical presentation
Peritonitis features masked
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Why diagnosis is difficult?
X-ray free air under diaphragm not in all perforation cases
X-ray evidence of obstruction,not the cause
CT abdomen cannot be done in
many acute abdomen cases
Diagnostic laparoscopy cannot be
done in all acute abdomen cases
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Does experience help?
For over 50 years that I have been
opening up patients abdomen, I am
constantly amazed at the variety of
pathology I have encountered.In spite of so many new
investigations at our disposal like
ultrasound, CT scan and MRI, thehuman belly defies them all andreveals its secret only when
confronted by a surgeons scalpel.
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Does experience help?
Surgery never runs out ofsuspenseful surprises.
The last operation that a surgeon
performs on the abdomen beforeretiring, he might see something he
has never seen before.
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At the end of all this .,
Decided whether it is abdomen witha surgical cause or not
Not necessary to make a exactdiagnosis though we should beaware of the possibilities
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Let me end with a story
A weekend party amongstudents, interns, GPs andsurgeons by the river side
A bird seen
A student says look at that
bird, it may be a kite or tern orhawk or even a sea-gull
Intern looks like a either a tern
bird or sea-gull, it cant be the
other two
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GPs bird came from the south ,wings are characteristic of seagull,it is most probably a sea-gull
At the end the surgeon shoots thebird
go and confirm which birdit is
D i h f
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Does it mean we have a free
hand?Remember the story of Pandoras
box
Negative laparotomy- known entity
But better to err on the wrong side
it doesnt matter if you
arent right , but never be
wrong
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Take home messages
No short cuts to detailed historyand examination
Decide whether it is a surgicalabdomen
Serial assessment of bowel sounds
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Take home messages
Rule out pancreatitis in all acuteupper abdomen
Rule out perforation in all acuteabdomen
Rule out cause outside abdomen
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Another Pandorasbox is perhaps a
girls mind
Thank you