OTC Derivatives OTC Derivatives – Product History and Regulation September 2009.
Otc Practice Lec 2
Transcript of Otc Practice Lec 2
![Page 1: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/1.jpg)
HOW TO PRACTICE
O.T.C
Lecture two
![Page 2: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/2.jpg)
![Page 3: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/3.jpg)
Fever
Respiratory infection
renal infection
Gastroenteritis & appendicitis
Teething fever
Vomiting & diarrhea
Sneezing, fatigue, rhinorrhea
Cough& dyspnea
Pain on urination
Teething period< 2 y
Common cold
yes
No
yes
yes
yes
yes
No
No
No
Noantipyrtic
![Page 4: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/4.jpg)
Body temperature measurements:
�ْOral “sublingual: ” Good reflex of body temperature but usually lower than body temp due to breathing from mouth while taking temp.
Tympanic:
Due to high blood flow in tympanic membrane, so reflects body temp.
Axillaries
But its validity is questionable .
![Page 5: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/5.jpg)
Treatment
Supportive Cool bath, ice packs, fans reduce fever
Antipyretic: acetaminophen, Ibuprofen, ketoprofen or aspirin, declofenac
Antipyrtic should be taken after meal
NB: Aspirin should be avoided in children lower than 12 years due to risk Ray’s syndrome
![Page 6: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/6.jpg)
paracetamol
![Page 7: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/7.jpg)
Ibuprofen
ketoprofen
![Page 8: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/8.jpg)
declofenac
![Page 9: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/9.jpg)
Example of OTC prescription
Pyral syrp
االكل 3مل 10 بعد مرات
![Page 10: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/10.jpg)
![Page 11: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/11.jpg)
headache
sinusitis
migraine
Eye problemEye pain, blurred vision
Sinus congestion, pain in sinus areas
Throbbing pain in one side of headworsen with normal movements,
Give analgesicLike fever
yes
No yes
yesNo
No
![Page 12: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/12.jpg)
Prevention of headache
1 -avoid high amount of caffee, tea, ice cream, chocolate
2-avoid stress and avoid change normal routine as “dieting, traveling, sleeping”
![Page 13: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/13.jpg)
Treatment of migraine
Mild cases:
Acetaminophen plus metoclopramide
Sever cases:
Ergotamine combinationAvoid use in hypertensive patients or pregnant
![Page 14: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/14.jpg)
Paracetamol + metoclopramide
![Page 15: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/15.jpg)
ergotamine
![Page 16: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/16.jpg)
Example of OTC prescription for migrain
Migracid tab
اللزوم 1-2 عند قرص
![Page 17: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/17.jpg)
![Page 18: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/18.jpg)
insomnia
Drug induced
Physician contactPsychological causes or sever pain
On starting drug use
Give first generation antihistaminicor natural sedating product
yes
No
yes
No
![Page 19: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/19.jpg)
Prevention of insomnia “sleep hygiene”
1-avoid CNS stimulant drugs
2-Hunger can inhibit sleep, so not go to bed hungry.
3-Avoid coffee, smoking completely after noon.
4-Bed room should be comfortable
5-avoid napping
![Page 20: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/20.jpg)
Treatment
Antihistaminic:
as diphenhydramine & doxylamine at bedtime
Plant extracts:
Valerians (Dormival)®
Kava kava extract (kava)®
![Page 21: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/21.jpg)
Plant extracts
![Page 22: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/22.jpg)
First gen. antihistaminic
![Page 23: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/23.jpg)
Example of OTC prescription:
Kava cap
النوم 2 – 1 قبل يوميًا� كبسوالتAvil retard tab
النو قبل يوميًا� م قرص
![Page 24: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/24.jpg)
![Page 25: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/25.jpg)
Fatigue & weakness
anemia
hyperthyroidism
Common coldFever & rhinorhea, sneezing
Recurrent Hypotension, palpitation, pale skin
Unintended potent weight loss, good appetite, sweeting, tachycardia, nervousness
Overworking or under eating is the cause
yes
Noyes
yesNo
No
Drug inducedOn starting drug useyes
![Page 26: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/26.jpg)
Treatment: “for fatigue & weakness
1-Caffeine stimulant:
NB: too much caffeine may cause nervousness, irritability & no sleep.
2-multivitamins
-Supply vitamins and minerals and energizers
-Avoid those concentrate on iron or calcium
-Multivitamins are taken once daily after meal
![Page 27: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/27.jpg)
multivitamins1 -royal jelly
2 -vitamins and minerals
2 -ginseng
4 -wheat germ oil
5 -antioxidant
6 -Bee pollen
![Page 28: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/28.jpg)
multivitamins
![Page 29: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/29.jpg)
![Page 30: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/30.jpg)
Example of OTC prescription:
Royal jelly 600 mg tab
الغداء بعد يوميًا� كبسولة
![Page 31: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/31.jpg)
![Page 32: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/32.jpg)
Back pain
Renal stone or infection
Sciatica (disc)
physicianAccident, fall, injury
Urine problem
Numbness or pain in one leg
Give analgesic, muscle relaxant
yes
Noyes
yesNo
NoOsteoarthritis or
rheumatic arthritisChronic pain, inflammation,
stiffness In both sides of joints
yes
![Page 33: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/33.jpg)
Treatment of back pain
1 -analgesic:acetaminophen, Ibuprofen, ketoprofen or aspirin, declofenac, piroxicam,celecoxib, nimasulide, indomethacin
2-muscle relaxntEX 1 :- Baclofen(Baclofen).® EX 2 :- Chlozoxazone (Myolgine) .®
EX 3:- Orphenadrine (Norflex).®
3-counter irritantMask the painNot applied to wound or damaged skin
![Page 34: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/34.jpg)
AntiCox 2
indomethacin
![Page 35: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/35.jpg)
Muscle relaxant and analgesic
![Page 36: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/36.jpg)
Example of OTC prescription:
myolgin cap
االكل 3كبسولة بعد مراتOlfen amp
يوميًا عضل حقنة
![Page 37: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/37.jpg)
![Page 38: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/38.jpg)
cough
Physician contact
Interfere with sleep or activity or painful
Respiratory infectionFever
Asthmatic patient
dry cough
Give antitussive
yes
Noyes
yesNo
No
Give mucolytic or expectorant
Productive
yes
cough suppressant + expectorant
yes
No
![Page 39: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/39.jpg)
Cough
Cough removes foreign bodies, so not recommend selling a cough suppressant to
smokers.
Productive cough brings up accumulated mucus preventing pneumonia, so must be allowed to be continued for its cleansing effect
![Page 40: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/40.jpg)
Treatment productive cough
Bromohexyine (Bisolvon)®
Ambroxol (Ambroxol)®
Active metabolite of bromohexine
Acetyl cystiene: (Acetyl cystiene) ® Powder
Carboxy methyl cystiene ( solvex):
![Page 41: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/41.jpg)
mucolytic
![Page 42: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/42.jpg)
mucolytic
![Page 43: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/43.jpg)
Treatment of dry cough
Cough suppressant ( antitussive) Central:
codeine Diphenhydramine; Dextromethorphane; Noscapine”, Pipozethate, Butamirate
Peripheral: camphor & Menthol
Codeine&Dextromethorphane have the risk of abuse ( addiction)& constipation.
![Page 44: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/44.jpg)
antitussive
![Page 45: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/45.jpg)
antitussive
![Page 46: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/46.jpg)
Expectorant & cough suppressant
Guaifensin
Ammonium cl
Tr. Ipeca
Tr. Squill
KI
Diphenhydramine
Dextromethorphane ;
Camphor
Menthol”
![Page 47: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/47.jpg)
Antitussive+ expectorant
![Page 48: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/48.jpg)
Natural preparations for cough
They act as cough suppressant and expectorant
Examples:
Guava leaves, fennel, thyme, honey, tilia, comphor, mentol.
Suitable for pregnant, patients with kideny, liver disorder.
![Page 49: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/49.jpg)
Natural cough product
![Page 50: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/50.jpg)
Example of OTC prescription for productive cough:
muco syrup
االكل بعد كبيرة مرات 3معلقة
![Page 51: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/51.jpg)
Example of OTC prescription for Dry cough:
sinecode syrup
االكل بعد كبيرة مرات 3معلقة
![Page 52: Otc Practice Lec 2](https://reader031.fdocuments.us/reader031/viewer/2022020713/548cbe6ab4795965088b478e/html5/thumbnails/52.jpg)
Example of OTC prescription for Combination Drug for cough:
Toplexil syrup
االكل بعد كبيرة مرات 3معلقة