METABOLIC SYNDROME

DR. AJIN JAYAN THOMAS,Department of Physiotherapy,Dr. D. Y. Patil University,Nerul, Navi Mumbai.

METABOLIC SYNDROME

Metabolic syndrome is a cluster of the most dangerous cardiovascular risk factors namely diabetes, abdominal obesity, high cholesterol and elevated blood pressure.

1923, Kylin described the clustering of hyperglycemia, hyperurecemia and hypertension.

1988, Reaven- Syndrome X referred to a group of connected disorders characterized by impaired glucose tolerance, dyslipidemia, hypertension, associated with increased risk of type 2 diabetes and cardiovascular disease.

METABOLIC SYNDROMESyndrome XInsulin resistance syndromeMetabolic syndrome X Cardiometabolic syndromeDysmetabolic syndrome Deadly quartetMultiple metabolic syndrome

SYNONYMS OF METABOLIC SYNDROME

World Health Organization (WHO) 1998Adult Treatment Panel III, 2003International Diabetes Foundation (IDF), 2005American Association of Clinical Endocrinologists (2003)European Group for the Study of Insulin Resistance, EGIRAmerican Heart Association (AHA) and National Heart, Lung and Blood Institute (NHLBI), 2005

Definitions & Criteria of Diagnosis

Any 3 of 5 constitute diagnosis of Metabolic Syndrome

Elevated Waist Circumference (cutoff for Asian Population)90 cm (35 inches) in Men 80 cm (31 inches) in WomenElevated Triglycerides150 mg/dL(1.7 mmol/L) Or On drug treatment for elevated TGReduced HDL-C