Jacques BenvenisteA TRUE LEGEND AMONG MYTHSThe preservation of an outstanding French scientist and his research

1Wednesday, July 9, 14

Outstanding French scientist Jacques Benveniste (1935-2004) - author of over 300 scientific articles on medicine related to the area of molecular biology, was known as a successful researcher who discovered a new, important lipid mediator. According to colleagues, Benveniste was a potential Nobel Prize candidate for his research discoveries.

Approaching the peak of success, Jacques Benveniste unexpectedly departed from the conventional scientific arena in order to concentrate on less traditional forms of research. In 1998, the authoritative London weekly scientific journal Nature published his article with co-authors Davenas, E., Beauvais, F., Amara, J., Oberbaum, M., Robvizon, B., Miadonna, A., Tedeschi, A., Pomeranz, B., Fortner, P., Belon, P., Sainte-Laudy, J., Poitevin, B. & Benveniste, J., Titled: Human basophil degranulation triggered by very dilute antiserum against IgE. Nature, 333, 816-818. The published article had presented astounding results from Benveniste unconventional research. The controversial article caused heated debates amongst the prevailing scientific dogma in physics, chemistry and biology.

The inability to consistently repeat his experiments resulted in Jacques Benveniste being rejected by the scientific community, deprived of laboratory accesses and dismissed from the INSERM in Paris. These harsh actions from the scientific community would eventually lead investigative researchers to consider if the Benviniste experiments had actually damaged the reputation of the institution.

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J. Benveniste’s research created a divide in the scientific community. Some scientists continued forward with these experiments in the study of this phenomena discovered by J. Benveniste. Based on scientific research findings they had also come to declare that J. Benveniste work was ethical and warranted further investigative research. Contrary to current knowledge and concepts, opposing scientific researchers would not accept the results.

In 2014, 26 years has passed since the J. Benveniste publication in the Nature journal, from which came the discovery phenomena journalists now call "Memory of Water”. The time has come, to find out who is right.

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Confirmation of the Benveniste resultsby independent researches:

• Belon P, Cumps J, Ennis M, Mannaioni PF, Sainte-Laudy J, Roberfroid M, et al. Inhibition of human basophil degranulation by successive histamine dilutions: results of a European multi-centre trial. Inflamm Res 1999; 48: S17–8.

• Brown V, Ennis M. Flow-cytometric analysis of basophil activation: inhibition by histamine at conventional and homeopathic concentrations. Inflamm Res 2001; 50(Suppl 2):S47–S48

• Lorenz I, Schneider EM, Stolz P, Brack A, Strube J. Sensitive flow cytometric method to test basophil activation influenced by homeopathic histamine dilutions. Forsch Komplementarmed Klass Naturheilkd 2003; 10:316–24.

• Belon, P, Cumps, J, Ennis, M et al. Histamine dilutions modulate basophil activation. Inflamm res 2004; 53:181-188.

+ several other studies of the same and other authors.

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In spite of hardships, Jacques Benveniste continued his research in a personal laboratory. He had acquired an even stronger character and an iron willpower that provided him footing to forge new pathways into his scientific research. He began new experiments - a transmission of signals from biologically active substances through communication lines.

Following Benveniste’s death in 2004, this direction of his charactered research is continued and expanded upon by successors alike, resulting in the further affirmations of the controversial experiments.

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Based on J. Benveniste observations; the effects of “Ultra-High Dilutions” were abolished by magnetic fields. He suggested that the signaling of EM waves are potentially transmittable to cells and water by electromagnetic means.

In 1991 Benveniste implemented the Electronic Transmission of “Informational Copies” (IC) of biologically active substances (BAS) to water.

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The Principle Scheme was that of a device for Electronic Transmission of IC of BAS Output coil Input coil Solution of BAS Amplifier (oscillator)

Water (IC of BAS).

Output coil

Inputcoil

Solution of BAS

Amplifier (oscillator)

Water (informational copy of

BAS)

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“…normal human neutrophils reacted to PMA transmitted via an electronic oscillator by reducing cytochrome c as though they had been directly exposed to PMA. This phenomenon was not observed when the oscillator was turned off…, when protein kinase inhibitors were added to neutrophils…, when active PMA in the input solution was substituted by its inactive analogue The results of 10 independent blind experiments Transmitted PMA Transmitted vehicle”The results of 10 independent blind experiments

Transmitted PMATransmitted vehicle

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IC of acetylcholine, histamine, ovalbumin and other BAS had been transmitted to distant addressees

using communication networks including Internet

J. Benveniste, P. Jurgens, W. Hsueh, J. Aissa TRANSATLANTIC TRANSFER OF DIGITIZED ANTIGEN SIGNAL BY TELEPHONE LINK. J. Allergy Clin. Immunol., 99:S175 (1997).

Benveniste, J., Benveniste L., Guillonnet, D. 2010. Method and system for producing a substance or a signal with a coagulating or anticoagulant effect. US Patent N◦ 0 233, 296 A1

J. Benveniste Paris, France

W. Hsueh Chicago, USA

Water treated with IC of BAS exerted specific effects on the biological test systems

Internet

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• Montagnier L., et al. (2009) Electromagnetic signals are produced by aqueous nanostructures derived from bacterial DNA sequences., Interdiscip. Sci. Comput. Life Sci., 1: 245-253.

• Montagnier, L., Aissa, J., Del Giudice, E., Lavallée, C., Tedeschi, A. & Vitiello, G. 2011. DNA waves and water. Journal of Physics: Conference Series. 306: 012007.

• Foletti A., et al. (2011) Differentiation of human LAN-5 neuroblastoma cells induced by extremely low frequency electronically transmitted retinoic acid. JACM 17(8), 701-704.

• Foletti A., et al. (2012) Experimental finding on the electromagnetic information transfer of specific molecular signals mediated through the aqueous system on two human cellular models. JACM 18(3), 258-261

• Foletti A. et al, Electromagnetic Information Delivery as a New Perspsctive in Medicine, PIERS Proceedings, Stockholm, Sweden, Aug. 12-15, 2013

• Citro M, Smith CW, Scott-Morley A, Pongratz W, Endler PC. Transfer of information from molecules by means of electronic amplification. In: Endler PC, Schulte J, editors. Ultra high dilution: physiology and physics. Dordrecht (Nederland): Kluwer Academic Pub.; 1994. 209-214.

• P. C. Endler, W. Pongratz, C. W. Smith, J. Schulte, F. Senekowitsch, M. Citro. Non-Molecular Information Transfer from Thyroxine to Frogs. Signals and Images 1997, pp 149-159

• J.A. Heredia-Rojas, R. Gomez-Flores, A. O. Rodriguez-de la Fuente, E. Monreal-Cuevas, A. C. Torres-Flores, L. E. Rodriguez-Flores, M. Beltcheva, A. C. Torres-Pantoja. Antimicrobial effect of amphotericin B electronicallyactivated water against Candida albicans. African journal of Microbiology Research 6(15). 2012, pp. 3685-3689

Confirmation of the Phenomena

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Existing scientific research in these subjects has lead us to the further inquiry and support of an outstanding French scientist by the name of Jacques Benveniste – a scientist, who challenged the dogma of modern thinking, and should be given a fair historical assessment.

THUS, THE PRINCIPLE OF ELECTRONIC TRANSMISSION OF BIOLOGICAL ACTIVITY OF

SPECIFIC SUBSTANCES ON AQUEOUS SYSTEMS IS CONFIRMED BY QUITE A FEW OF INDEPENDENT

RESEARCHERS.

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Brian Josephson, Nobel Laureate for Physics in 1973 invited Benveniste to the Cavendish Laboratory in Cambridge.

Josephson was quoted: ‘We invited him to learn more about the research which seems both scientifically interesting and potentially of considerable practical importance. Jacques definitely recognized there was a problem with reproducing the effect. The situation seemed to be that in some circumstances you had reproduction and in others you didn’t; but the overall results were highly significant.’

Brian Josephson had also made a point that many scientists have a "pathological disbelief" in certain subjects that ultimately create an unhealthy and unscientific attitude, thus creating blocks from real truth and real science. Skepticism is at its best when its advocates do not undermine the conversation of the subject at hand; but instead, explore all possible ways (conventional and non-conventional) to understand and verify strange but compelling phenomena. We all have this challenge as we explore and evaluate the biological and clinical effects of homeopathic medicines.

Support from Brian Josephson

Yolene Thomas. The history of the Memory of Water. Homeopathy (2007) 96, 151–157Article of Dana Ullman. Evidence Based HomeopathLinks:

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A recent interview in the journal Science, Luc Montagnier (Nobel Laureate in 2008 for discovering the AIDS virus) expressed real concern about the unscientific atmosphere that presently exists on certain unconventional subjects.

"I am told that some people have reproduced Benveniste's results, but they are afraid to publish it because of the intellectual terror from people who don't understand it.“

Montagnier concluded the interview when asked if he is concerned that he is drifting into pseudoscience, he replied adamantly: "No, because it's not pseudoscience. It's not quackery. These are real phenomena which deserve further study…For me Jacques Benveniste is a great researcher, as you pointed out, and it's really scandalous the way he was treated. He died, as you know, in 2004, we can say exhausted by all that struggling and I believe that one day soon, he will be completely rehabilitated. I think it is a matter as important as the Galileo affair.”

Support from Luc Montagnier

Article of Dana Ullman. Evidence Based HomeopathFrance-Inter - Stéphane Paoli et Sandra Freeman, May 2, 2010Links:

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In memoriam Jacques Benveniste, Chicago, Illinois, USA, March 2005 

Support from Wei Hsueh

Link:

Prof. Wei Hsueh, M.D., Chicago, Illinois, USA:

“…It was disaster after disaster.  Things turned upside down. Gradually, everything was taken away from him: his budget, his staff, and finally his lab.  Till today I can’t understand how come the scientific community in France and in the world turned a completely deaf ear to the success of his subsequent experiments that confirmed the earlier results of the Nature paper? The study, as you all know, was performed in collaboration with none other than Dr. Spira, a leading statistician in France, and the data were supported by impeccable statistical analysis.

When I met Jacques again in a meeting a few years later, I thought he would have looked defeated and dejected. I was certain that he would give up his unorthodox research, and return to the main stream. It was quite the contrary. Jacques appeared highly spirited, and told me that he had launched a new research project using electronically transmitted signals to stimulate human neutrophils…

…This peculiar discovery may sound something of only casual interest for the curious, but if you think about it carefully, you’ll realize that its potential impact is enormous… 

…Most importantly, this discovery changed our entire traditional concept about biology…”

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• L Montagnier, J Aissa, E Del Giudice, C Lavallee, A Tedeschi and G Vitiello. DNA waves and water. Journal of Physics: Conference Series 306 (2011) 012007.

• P.C. Endler. Pretreatment with Thyroxine (10-8 Parts by Weight) Enhances a 'Curative' Effect of Homeopathically Prepared Thyroxine (10-13) on Lowland Frogs. Forsch Komplementärmed Klass Naturheilkd 2003;10:137-142

• P.C. Endler. The effect of highly diluted agitated thyroxine on the climbing activity of frogs. Vet Human Toxicol 36(1). 1994

• V. I. Korenbaum, T. N. Chernysheva, T. P. Apukhtina, S. N. Shin, V. N. Demenok. Effect of electronic homeopathic copy of biohumus fertilizer on tomato sprout development.Thermoluminescence of ultra-high dilutions of lithium chloride and sodium chloride. Radiative biology. Radioecology, 2003, 43, #3: 373-377.

• Louis Rey. Thermoluminescence ofultra-high dilutions of lithium chloride and sodium chloride. Physica A, 323 (2003): 67-74.

• E. Davenas, B. Poitevin, J. Benveniste. Effect on mouse peritoneal macrophages of arally administred very high dilutions of silica. European journal of Pharmacology, 135 (1987): 313-319

• P. Bellavite et al. Immunology and Homeopathy. 1. Historical background. Evidence-Based Complementary and Alternative Medicine (2005). Vol.2(4):441-452

• Del Giudice, E., Preparata, G., Vitiello, G. 1988. Water as a free electric dipole laser. Physical Review Letters, 61, 1085.

• Zhadin M. New ideas on structure of water and of aqueous solutions on the basis of modern quantum electrodynamics of condensed matter as applied to biological and medical problems. New informational technologies in medicine, biology, pharmacology and ecology, 2007 : 127-129

• J. Benveniste, J. Aïssa, P. Jurgens,W. Hsue. Specificity of the digitized molecular signal. FASEB, 1998.

• Benveniste et al. Method, system and device for producing signals from a substance biological and/or chemical activity. United States Patent # US 6,541,978 B1, 2003

• Butters. System and method for sample detection based on low-frequency spectral components. United States Patent: US 7,412,340 B2. 2008

Works that prove the existence of natural phenomena discovered by Jacques Benveniste

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• E. Del Giudice, A. Tedeschi. Water and the autocatalysis in living matter. Electromagnetic Biology and Medicine. Vol. 28(1) 2009.

• P. Bellavite et al. Immunology and Homeopathy. 2. Cells of the Immune System and Inflammation. Evidence-Based Complementary and Alternative Medicine (2006). Vol.3 (1):13-24

• E. B. Burlakova. Specific Effects of Superlow Doses of Biologically Active Substances and Low-Level Physical Factors. Misaha Newsletter (2000): 390-424.

• A.L. Vereshchagin, T.L. Tsoi, V.V. Kropotkina. Application of ultra-low doses of biologically active substances and homeopathic remedies in plant. Polzunovskiy vestnik (2006). 2: 343-348.

• Davenas, E., Poitevin, B. & Benveniste, J. Effect on mouse peritoneal macrophages of orally administered very high dilutions of silica. Eur. J. Pharmac. (1987), 135, 313-319.

• Davenas, E., Beauvais, F., Amara, J., Oberbaum, M., Robvizon, B., Miadonna, A., Tedeschi, A., Pomeranz, B., Fortner, P., Belon, P., Sainte-Laudy, J., Poitevin, B. & Benveniste, J. (1988). Human basophil degranulation triggered by very dilute antiserum against IgE. Nature, 333, 816-818.

• Poitevin B, Davenas E, Benveniste J. In Vitro immunological degranulation of human basophils is modulated by lung histamine and Apis mellifica. Br J Clin Pharmacol 1988;25:439—44.

• Benveniste, J., Guillonnet, D. 2004. Method and device for avoiding alteration of a substance having biological activity. US Patent N◦ 0 038, 937 A1.

• Benveniste, J., Benveniste L., Guillonnet, D. 2010. Method and system for producing a substance or a signal with a coagulating or anticoagulant effect. US Patent N◦ 0 233, 296 A1

• Benveniste, Ja., Benveniste Je., Benveniste V., Benveniste L., Benveniste C., Benveniste A. 2010. Method and system for providing a substance with receptive and/or transmissive properties for a signal. US Patent N◦ 0 272, 629 A1

• Belon, P, Cumps, J, Ennis, M et al. Histamine dilutions modulate basophil activation. Inflamm res 2004;53:181-188.

• L. Montagnier, C. Lavallee, J. Aissa. 2012. General procedure for the identification of DNA sequences generating electromagnetic signals in biological fluids and tissues. US Patent N◦ 2012/0024701 A1.

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• А. Foletti, M. Ledda, E. D'Emilia, S. Grimaldi, A. Lisi. Experimental Finding on the Electromagnetic Information Transfer of Specific Molecular Signals Mediated Through the Aqueous System on Two Human Cellular Models. The Journal of Alternative and Complementary Medicine. 2012, 18(3): 258-261.

• Vileninovna SN, Scherbina LV, Sorokoletov VV, Method of bioinformational characteristics recording. Russian patent #2114598

• J.A. Heredia-Rojas, R. Gomez-Flores, A. O. Rodriguez-de la Fuente, E. Monreal-Cuevas, A. C. Torres-Flores, L. E. Rodriguez-Flores, M. Beltcheva, A. C. Torres-Pantoja. Antimicrobial effect of amphotericin B electronicallyactivated water against Candida albicans. African journal of Microbiology Research 6(15). 2012, pp. 3685-3689.

• R. Miranda, A. Vannucci and W. M. Pontuschka. Impedance spectroscopy of water in comparison with high dilutions of lithium chloride. Materials Research Innovations (2011), 15(5): 302-309.

• C. Takano, A. R. Miranda, A. Vannucci. Impedance Spectroscopy applied to the study of high dilutions of Lycopodium clavatum. Int J High Dilution Res (2011) 10(36):101-103.

• I.S. Ryzhkina, L.I. Murtazina, E.D. Sherman, Yu.N. Valitova, E.A. Kataev, A.I. Konovalov, Low-concentration aqueous solutions of macrocyclic pyridine-pyrrole compound: relationship between the parameters, physicochemical properties, and physiological activity of supramolecular nanosized associates. Doklady Physical Chemistry, 2010, vol. 433, part 2, pp. 142-146.

• Bellavite P. et al. Immunology and Homeopathy. 2. Cells of the Immune System and Inflammation, eCAM 2006;3(1)13–24

• Sainte-Laud J, Belon P. Inhibition of basophil activation by histamine: a sensitive and reproducible model for the study of the biological activity of high dilutions. Homeopathy 2009;98:186-197.

• Van Wijk R, Bosman S, van Wijk EP. Thermoluminescence in ultra-high dilution research. J Altern Complement Med 2006;12:437-443.

• Demangeat JL. Nanosized solvent superstructures in ultramolecular aqueous dilutions: twenty years' research using water proton NMR relaxation. Homeopathy 2013;102:87-105.

• Thomas Y, Schiff M, Belkadi L, Jurgens P, Kahhak L, Benveniste J. Activation of human neutrophils by electronically transmitted phorbolmyristate acetate. Med Hypotheses 2000; 54:33-39.

• Benveniste, J. et al. Transatlantic transfer of digitized antigen signal by telephone link. J. Allergy clin. Immunol., 99:s175 (1997)

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• P. C. Endler, W. Pongratz, C. W. Smith, J. Schulte, F. Senekowitsch, M. Citro. Non-Molecular Information Transfer from Thyroxine to Frogs. Signals and Images 1997, pp 149-159

• S Weber, PC Endler et al. The effect of homeopathically prepared thyroxine on highland frogs: influence of electromagnetic fields. Homeopathy (2008) 97, 3–9

• Citro M, Smith CW, Scott-Morley A, Pongratz W, Endler PC. Transfer of information from molecules by means of electronic amplification. In: Endler PC, Schulte J, editors. Ultra high dilution: physiology and physics. Dordrecht (Nederland): Kluwer Academic Publishers; 1994. 209-214.

• Foletti A., et al. (2011) Differentiation of human LAN-5 neuroblastoma cells induced by extremely low frequency electronically transmitted retinoic acid. JACM 17(8), 701-704.

• Foletti A. et al, Electromagnetic Information Delivery as a New Perspsctive in Medicine, PIERS Proceedings, Stockholm, Sweden, Aug. 12-15, 2013

• Sainte-Laudy J, Belon P. Analysis of immunosuppressive activity of serial dilutions of histamine on human basophil activation by flow cytometry. Inflamm Res 1996; 45(Suppl 1): S33–S34.

• Brown V, Ennis M. Flow-cytometric analysis of basophil activation: inhibition by histamine at conventional and homeopathic concentrations. Inflamm Res 2001; 50(Suppl 2): S47–S48.

• Lorenz I, Schneider EM, Stolz P, Brack A, Strube J. Sensitive flow cytometric method to test basophil activation influenced by homeopathic histamine dilutions. Forsch Komplementarmed Klass Naturheilkd 2003; 10: 316–324.

• Chirumbolo S, Brizzi M, Ortolani R, Vella A, Bellavite P. Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study. Inflamm Res 2009; 58: 755–764.

• Currently HomBrex contains 2045 experiments published in 1518 original articles http://www.carstens-stiftung.de/hombrex/index.php

Hundreds of papers which represent researches in physics, biology, and medicine, experimentally confirm the existence of

phenomena discovered by Jacques Benveniste

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The damaging bureaucracy of academic peer review along with academic funding agencies should show support for research in unfashionable fields. Support for research that might lead to advanced major scientific discoveries is virtually forbidden nowadays. We call upon funding agencies to support sustained, open-ended research in unfashionable fields:

Donald W Braben, University College London; John F Allen, Queen Mary, University of London; William Amos, University of Cambridge; Richard Ball, University of Edinburgh; Tim Birkhead, FRS, University of Sheffield; Peter Cameron, Queen Mary, University of London; Richard Cogdell FRS, University of Glasgow; David Colquhoun FRS, University College London; Rod Dowler, Industry Forum, London; Irene Engle, United States Naval Academy, Annapolis; Felipe Fernández-Armesto, University of Notre Dame; Desmond Fitzgerald, Materia Medica; John Hall, University of Colorado, Nobel Laureate; Pat Heslop-Harrison, University of Leicester; Dudley Herschbach, Harvard University, Nobel Laureate; H Jeff Kimble, Caltech, US National Academy of Sciences; Sir Harry Kroto FRS, Florida State University, Nobel Laureate; James Ladyman, University of Bristol; Peter Lawrence FRS, University of Cambridge; Angus MacIntyre FRS, Queen Mary, University of London; John Mattick FAA, Garvan Institute of Medical Research, Sydney; Beatrice Pelloni, University of Reading; Douglas Randall, University of Missouri; David Ray, Bio Astral Limited; Sir Richard J Roberts FRS, New England Biolabs, Nobel Laureate; Ken Seddon, Queen’s University of Belfast; Colin Self, University of Newcastle; Harry Swinney, University of Texas, US National Academy of Sciences; Claudio Vita-Finzi FBA, Natural History Museum.

Link: The Telegraph, 02 Jun 2014

Presently, the phenomena discovered by Jacques Benveniste has begun to garner much deserved attention and is need of further support from

fundamental researchers.

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The above presented materials stand as a foundation for the justification of Jacques Benveniste and his research discoveries. The biological and physical properties of water, including the transfer of signals from biologically active substances are actual and attested. The implications of this natural phenomena have vast applications in multiple areas of human activity; and in particular, are already used in the fields of healthcare.

The Outstanding French Scientist was far ahead of his time and has made one of the greatest scientific breakthroughs in recorded history. In the visage of our beloved science, the time is now upon us to restore justice by giving tribute to a man who has devoted himself wholeheartedly and suffered for his beliefs.

Please join us in our righteous efforts by signing onto our international initiative group. Our main initiative is the restoration of the honest name Jacques Benveniste.

For contacts: Anton Fedorenko, faa@phystech.eduJeremy Pfeiffer, jeremy@waterconf.com

A portion of materials for this presentation is provided by the web-site of: ASSOCIATION JACQUES BENVENISTE POUR LA RECHERCHE

International initiative to restore honest name of Jacques Benveniste

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