Honours in Applied Medical Science - University of...

32
Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead Examples of projects offered in 2018 Artist’s impression Artist’s Impression

Transcript of Honours in Applied Medical Science - University of...

Page 1: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Sydney. Science. Westmead.

Honours in Applied Medical Science at Westmead

Examples of projects offered in 2018

Artist’s impression

Artist’s Impression

Page 2: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead
Page 3: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

With 100 000 people moving to the area every year, western Sydney is one of the fastest growing places in Australia. At the geographical heart of Sydney, Westmead is fast becoming a major centre of activity. Over $5 billion of investment and development is expected to take place in Westmead by 2030, with an emphasis on large-scale expansion and transformation of the existing hospitals and medical research institutes located there.The Westmead Precinct is a world-class centre of health research, education and services, employing over 1000 full-time scientists. The scale and diversity of activity at Westmead is unparalleled, including six major research institutes and centres co-located with four hospitals delivering healthcare to millions of patients every year.

Why Study at Westmead

Exciting translational researchThe Honours in Applied Medical Science program at Westmead has over 150 projects on offer in 2018 across the precinct, so there is bound to be a project that covers your interests. Projects are very broad in scope including basic research, public health, social sciences and allied health. Major specialities include cancer, infectious diseases, immunology, physiology, obesity and diabetes, neuroscience and dentistry. Westmead scientists and researchers are leaders in their fields working in close collaboration with clinicians, giving unparalleled opportunities for ‘bench to bedside’ translational research which provide students with unique opportunities to get involved in research that has a meaningful impact on the health of our community. Artist’s impression

Western Sydney is booming

Page 4: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

A systematic review of diet and nutrition interventions among people with Motor Neuron Disease

Vicki FloodEmail: [email protected]

Phone:0412 118 977

Institute:Adult hospital

Projects*Please note, these are indicative projects and are subject to change.

Allied Health

Application of Mediterranean Diet among culturally diverse population groups of Western Sydney

Vicki FloodEmail: [email protected]

Phone:0412 118 977

Institute:Adult hospital

CancerPredictors of endocrine treatment response in low-grade serous ovarian cancer

Anna deFazioEmail: [email protected]

Phone:8627 3740

Institute:WIMR

Development of a Computer Aided Diagnosis (CAD) technique for early detection of melanomaEmail: [email protected]

Phone:8890 5686

Institute:Adult hospital

Influence of chromatin architecture on transcriptional function of hormone receptors

Email: [email protected]

Phone:9845 6954

Institute:WIMR

Space Invaders: How Cancer cells negotiate tissue barriers

Email: [email protected]

Phone:9845 1206

Institute:SCHN

Ashni Kumar

Dinny Graham

Geraldine O'Neill

Page 5: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

A weighty problem- targeting the lipid droplets in cancer cell lines

Email: [email protected]

Phone:9845 3027

Institute:SCHN

Interactions between sleep and cancer

Email: [email protected]

Phone:9845 6797

Institute:WIMR

Jennifer Byrne

Kristina Kairaitis

Hilda Pickett

Investigating the role of a novel RNA binding protein in telomerase activity

Email: [email protected]

Phone:9687 2800

Institute:CMRI

Hilda Pickett

Understanding protein dephosphorylation in the DNA damage response

Email: [email protected]

Phone:9687 2800

Institute:CMRI

Identifying targets to improve therapy of high-risk and relapsed paediatric cancer patients

Email: [email protected]

Phone:9845 3027

Institute:SCHN

Jennifer Byrne

Effects of Strigolactones on liver cancer: in vitro studies

Email: [email protected]

Phone:6879 3534

Institute:WIMR

Liang Qiao

Nutrient regulation of the stem cell in cancer

Email: [email protected]

Phone:8627 3159

Institute:WIMR

Jacob George

Page 6: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Possible role of constitutive androstane receptor (CAR) in liver cancer

Email: [email protected]

Phone:6879 3534

Institute:WIMR

Liang Qiao

Screening of long non-coding RNAs (lncRNAs) in liver cancer stem cell tumorigenesisEmail: [email protected]

Phone:6879 3534

Institute:WIMR

Liang Qiao

Proteomic analysis of Stratum Corneum in cutaneous Squamous Cell Carcinoma (SCC)

Email: [email protected]

Phone:8890 5686

Institute:Adult hospital

Pablo Fernandez Penas

Proteomic analysis of Cutaneous T cell lymphomas (CTCL) using Scarless biopsy

Email: [email protected]

Phone:8890 5686

Institute:Adult hospital

Pablo Fernandez Penas

CTCL proteomics in Formalin Fixed Paraffin Embedded (FFPE) tissue

Email: [email protected]

Phone:8890 5686

Institute:Adult hospital

Pablo Fernandez Penas

Comparison, validation and characterisation of primary human cutaneous squamous call carcinoma cells (cSCC) isolated and cultured using different techniques

Email: [email protected]

Phone:8890 5686

Institute:Adult hospital

Pablo Fernandez Penas

Identification and development of telomerase inhibitors as potential cancer therapeutics

Email: [email protected]

Phone: 9687 2800

Institute:CMRI

Scott Cohen

Page 7: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

The telomere deprotection and cancer

Email: [email protected]

Phone: 8865 2912

Institute:CMRI

Tony Cesare

Biochemistry and cell biology of the cancer-associated enzyme telomerase

Email: [email protected]

Phone: 9687 2800

Institute:CMRI

Tracy Bryan

Comparison of non-invasive home studies to in laboratory polysomnography for children

Email: [email protected]

Phone: 9845 3437

Institute:CMRI

Karen Waters

Use of glyceryl trinitrate in the modulation of inflammatory milieu in preeclampsia (PE) and intrauterine fetal growth restriction (IUGR) –basic and clinical applications.

Email: [email protected]

Phone: 8890 4851

Institute:Adult Hospital

Indika Alahakoon

The DNA replication stress response

Email: [email protected]

Phone: 8865 2912

Institute:CMRI

Tony Cesare

Clinical

What can sleep studies tell us about enuresis?

Email: [email protected]

Phone: 9845 3437

Institute:CMRI

Karen Waters

Maternal KIRs and fetal HLA C genotype and its association with the risk of preeclampsia and IUGR

Email: [email protected]

Phone: 8890 4851

Institute:Adult Hospital

Indika Alahakoon

Page 8: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Gene Identification and Treatment in Genetic Kidney Disease

Email: [email protected]

Phone: 9845 3408

Institute:SCHN

Stephen Alexander

Investigating the role of thrombospondin-1 and CD47 in diabetes mellitus and islet cell transplantationEmail:[email protected]

Phone:9847 7365

Institute:WIMR

Natasha Rogers

2DL1 and 2DS1 KIRs gene mutational screening for preeclampsia and IUGR patients

Email: [email protected]

Phone: 8890 4851

Institute:Adult Hospital

Indika Alahakoon

Biomarkers in kidney disease

Email:[email protected]

Phone:9847 7365

Institute:WIMR

Natasha Rogers

Treating inflammation to improve kidney transplant outcomes

Email: [email protected]

Phone: 9847 7365

Institute:WIMR

Natasha Rogers

Preventing fibrosis leading to chronic kidney disease

Email: [email protected]

Phone: 9847 7365

Institute:WIMR

Natasha Rogers

Targeting Regulatory T Cells for the Treatment of Autoimmune Disease Email: [email protected]

Phone: 9845 3408

Institute:SCHN

Stephen Alexander

Page 9: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Development of live-cell biomarkers to probe cell molecular states in live-cell imaging experiments

Email: [email protected]

Phone: 0402 613 576

Institute:IDR

James Cornwell

Assessment of and improvement to Clinical Islet Cell Isolation Outcomes for Transplantation

Email: [email protected]

Phone: 9846 7365

Institute:WIMR

Wayne Hawthorne

Kidneytext - improving dietary and lifestyle behaviour in people with chronic kidney disease on haemodialysis using a text message-based interventionEmail: [email protected]

Phone: 9845 6962

Institute:WIMR

Vincent Lee

Glomerular Podocyte Injury and Repair Mechanisms?

Email: [email protected]

Phone: 9845 3408

Institute:SCHN

Stephen Alexander

Alternative approaches to preventing rejection in transplant models. Focusing on islet cell transplantation

Email: [email protected]

Phone: 9846 7365

Institute:WIMR

Wayne Hawthorne

Dental

Investigating single-cell growth dynamics by live-cell imaging and single-cell tracking

Email: [email protected]

Phone: 0402 613 576

Institute:IDR

James Cornwell

Page 10: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

The oral microbiome beyond bacteria – what role do fungi play in establishing good oral health in childhood?

Email: [email protected]

Phone: 8890 4818

Institute:IDR/WIMR

Christina Adler

Kidney transplants and oral health in children

Email: [email protected]

Phone: 0437 487 452

Institute:IDR

Joerg Eberhard

Quantifying cell-cell and cell-microenvironment interactions and their effect on cell fate inheritance

Email: [email protected]

Phone: 0402 613 576

Institute:IDR

James Cornwell

Gamma-delta cells in oral epithelial tissues during different stages of inflammation Email: [email protected]

Phone: 0437 487 452

Institute:IDR

Joerg Eberhard

Periodontitis as a potential trigger of oxidative stress in the brain: A potential link between inflammation and depressive symptoms in older adults

Email: [email protected]

Phone: 0437 487 452

Institute:IDR

Joerg Eberhard

Nutritional effects for oral health: Microbiome, caries experience and periodontal health

Email: [email protected]

Phone: 0437 487 452

Institute:IDR

Joerg Eberhard

Expression of human serum amyloid A protein in inflamed gingival epithelium

Email: [email protected]

Phone: 9845 8766

Institute:IDR

Jinlong Gao

Page 11: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Mutagenesis study of LptO - a essential component of Type IX secretion system in Porphyromonas gingivalis

Email: [email protected]

Phone: Institute:IDR

Ky-Anh Nguyen

Molecular characterization of cell cycle regulation and epithelial-mesenchymal transition during the initiation phase of epithelial carcinoma

Email: [email protected]

Phone: 8890 4818

Institute:IDR

Naisana Seyedasli

Comparative and binding analysis of the bacterial HusA haemophorehomologs to explore the function evolution of periodontal pathogen Porphyromonas gingivalis

Email: [email protected]

Phone: 9845 8766

Institute:IDR

Jinlong Gao

Exploring the antibacterial potential of oxalate nanocrystal in dentistry

Email: [email protected]

Phone: 9845 8766

Institute:IDR

Jinlong Gao

Activation of inflammasome by oral Campylobacter concisus in a cultured oral epithelial cell model

Email: [email protected]

Phone: 9845 8766

Institute:IDR

Jinlong Gao

The role of Bone morphogenic protein (BMP) signaling pathway in chemoresistance and epithelial plasticity of human epithelial carcinoma

Email: [email protected]

Phone: 8890 4818

Institute:IDR

Naisana Seyedasli

Activation of inflammasome by oral Campylobacter concisus in a cultured oral epithelial cell model

Email: [email protected]

Phone: 9845 8767

Institute:IDR

Ping Ye

Page 12: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Gene therapy for genetic and acquired diseases of the liver and haematopoietic system

Email: [email protected]

Phone: 9845 3071

Institute:CMRI

Ian Alexander

Expression of human serum amyloid A protein in inflamed gingival epithelium

Email: [email protected]

Phone: 9845 8767

Institute:IDR

Ping Ye

Therapeutic role ATR-DNA Damage signalling in autosomal dominant polycystic kidney disease

Email: [email protected]

Phone: 9845 6962

Institute:WIMR

Gopala Rangan

Genetics/Genomics/Development

Biomarkers in the progression of autosomal dominant polycystic kidney disease

Email: [email protected]

Phone: 9845 6962

Institute:WIMR

Gopala Rangan

Discovery of ancient and contemporary adeno-associated viruses in Australian marsupials Email: [email protected]

Phone: 9845 3071

Institute:CMRI

Ian Alexander

Development of novel viral vectors for genome editing applications

Email: [email protected]

Phone: 8865 2818

Institute:CMRI

Leszek Lisowski

Page 13: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

In silico methods to create novel AAV capsid libraries

Email: [email protected]

Phone: 8865 2818

Institute:CMRI

Leszek Lisowski

Development of platform technologies for large scale AAV manufacturing

Email: [email protected]

Phone: 8865 2818

Institute:CMRI

Leszek Lisowski

Development of Mass Spectometry (MS) based method to evaluate capsid composition of AAV vectors

Email: [email protected]

Phone: 8865 2818

Institute:CMRI

Understanding molecular interactions between AAV vectors and human cells

Email: [email protected]

Phone: 8865 2818

Institute:CMRI

In vitro evolution of novel AAV variants for efficient transduction of muscle satellite cells

Email: [email protected]

Phone: 8865 2818

Institute:CMRI

Leszek Lisowski

Leszek Lisowski

Leszek Lisowski

Directed Evolution of AAV vectors for therapeutic targeting of human retina

Email: [email protected]

Phone: 8865 2818

Institute:CMRI

Leszek Lisowski

Influence of AAV genome sequence on vector assembly (in silicomodelling and in vitro evaluation)

Email: [email protected]

Phone: 8865 2818

Institute:CMRI

Leszek Lisowski

Page 14: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Genomic medicine and the hunt for new disease genes in nerve and muscle disorders

Email: [email protected]

Phone: 9845 1456

Institute:CHW/KRI

Leigh Waddell

Head Development: Intersection of transcriptional and signalling activities

Email: [email protected]

Phone: 8865 2911

Institute:CMRI

Patrick Tam

Investigating the Role of Intronic SNP of SHROOM3 in Kidney Inflammation and Injury after Renal Ischemia-reperfusion Injury

Email: [email protected]

Phone: 8627 3501

Institute:WIMR

Phillip O’Connell

Control of cell differentiation during mouse embryogenesis and stem cell development

Email: [email protected]

Phone: 8866 2911

Institute:CMR

Pathways to therapies in blinding genetic retinal eye diseases

Email: [email protected]

Phone: 9845 3273

Institute:CMR

Pierre Osteil

Robyn Jamieson

Genomic medicine for unravelling the challenges of pathogenesis and treatment of blindness due to childhood cataract and glaucoma

Email: [email protected]

Phone: 9845 3273

Institute:CMR

Robyn Jamieson

Contemporise the Neuromuscular genetic variant database

Email: [email protected]

Phone: 9845 1456

Institute:CHW/KRI

Sandra Cooper

Page 15: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Investigating the Immunology of Crohn's Disease Using Human Intestinal Tissue

Email: [email protected]

Phone: 8627 2623

Institute:WIMR

Andrew Harman

Synergetic effects of antibiotics for the treatment of multidrug resistant Gram-negatives

Email: [email protected]

Phone: 8890 6255

Institute:ICPMR

Andrew Ginn

Refining algorithms for analysis and interpretation of splicing variants in genetic disorders

Email: [email protected]

Phone: 9845 1456

Institute:CHW/KRI

Sandra Cooper

Infectious Disease/Immunology

Investigating the Dynamics of Sexual Transmission of HIV Using Human Anogenital Tissues

Email: [email protected]

Phone: 8627 2623

Institute:WIMR

Andrew Harman

Distribution of Intracellular MICs against Salmonella Typhimurium

Email: [email protected]

Phone: 8890 6255

Institute:ICPMR

Andrew Ginn

Defining the HIV target cells in inflamed human mucosal tissue and their role in sexual transmission

Email: [email protected]

Phone: 8627 2623

Institute:WIMR

Andrew Harman

Page 16: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

How do herpes simplex viruses interact with dendritic cells in human skin: clues for vaccine development

Email: [email protected]

Phone: 8627 3001

Institute:WIMR

Anthony Cunningham

Effects of antibiotics on the ecology of enterobacteria and horizontal gene transfer in the EnterobacteriacaeEmail: [email protected]

Phone: 8627 3415

Institute:WIMR

Carola Venturini

The Role of Lambda Interferons in Immune Cell Migration to Sites of Inflammation

Email: [email protected]

Phone: 9845 7986

Institute:WIMR

Golo Ahlenstiel

Monocyte metabolism with increased cardiovascular disease risk

Email: [email protected]

Phone: 8890 3668

Institute:Adult Hospital

Heather Medbury

Does CpG island methylation affect Vitamin D Receptor regulation of gene expression?

Email: [email protected]

Phone: 8627 3602

Institute:WIMR

David Booth

Is EBV miRNA in immune cells dysregulated in MS?

Email: [email protected]

Phone: 8627 3602

Institute:WIMR

David Booth

Generation of human colonoids to examine gut immune responses

Email: [email protected]

Phone: 9845 7986

Institute:WIMR

Golo Ahlenstiel

Page 17: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Determining how fungi cause meningitis

Email: [email protected]

Phone: 8627 3420

Institute:WIMR

Julianne Djordjevic

Induction Of Transplant Tolerance in Mouse Transplantation Models

Email: [email protected]

Phone: 8627 3509

Institute:WIMR

Min Hu

The influence of hepatitis B virus genotype and HBx mutations on the development of liver cancer

Email: [email protected]

Phone: 9845 7705

Institute:WIMR

Mark Douglas

Interactions between Hepatitis Delta Virus (HDV) and Hepatitis B Virus (HBV)

Email: [email protected]

Phone: 9845 7705

Institute:WIMR

Mark Douglas

Is HIV/fungal co-infection synergistic for disease severity?

Email: [email protected]

Phone: 8627 3420

Institute:WIMR

Julianne Djordjevic

Role of IL-7 and IL-7/anti-IL-7 Antibody Complexes in Treg Expansion in Vitro and in Vivo a Murine Skin Transplant Model

Email: [email protected]

Phone: 8627 3509

Institute:WIMR

Min Hu

Tracking Foxp3 Tregs by Foxp3 GFP Report Gene in Vivo in a Transplant Tolerant Model

Email: [email protected]

Phone: 8627 3509

Institute:WIMR

Min Hu

How does monocyte metabolism contribute to fungal meningitis?

Email: [email protected]

Phone: 8627 3420

Institute:WIMR

Julianne Djordjevic

Page 18: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Role Of Herpes Simplex Virus Envelope Protein pUS9 In Virus Transport And Assembly In Sensory Axons

Email: [email protected]

Phone: 8627 3624

Institute:WIMR

Monica Miranda Saksena

Defining the interaction of HIV with the interferon system in initial mucosal infectionEmail: [email protected]

Phone: 8628 3622

Institute:WIMR

Najla Nasr

Gene therapy for arthritisEmail: [email protected]

Phone: 9847 6305

Institute:Adult Hospital

Nicholas Manolios

Plasmid interference and curing antibiotic resistance from EnterobacteriaceaeEmail: [email protected]

Phone: 8627 3417

Institute:WIMR

Muhammad Kamruzzaman

Drug design and development for arthritis

Email: [email protected]

Phone: 9847 6305

Institute:Adult Hospital

Nicholas Manolios

Drug delivery using endocannibinoids in arthritis

Email: [email protected]

Phone: 9847 6305

Institute:Adult Hospital

Nicholas Manolios

Arthritis research

Email: [email protected]

Phone: 9847 6305

Institute:Adult Hospital

Nicholas Manolios

Determining the Mechanism and Scope of Action of an Immunomodulatory Peptides in T-cell Function

Email: [email protected]

Phone: 9847 6305

Institute:Adult Hospital

Nicholas Manolios

Page 19: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Investigating regulatory T and B cells in children with atopic disorders

Email: [email protected]

Phone: 9845 3420

Institute:SCHN

Peter Hsu

Understanding the immune response to eye infections: The hope for limiting sight threatening tissue damage

Email: [email protected]

Phone: 0403 976 245

Institute:WIMR

Nicole Carnt

Targeted Nanoassemblies for the Treatment of Arthritis

Email: [email protected]

Phone: 9847 6305

Institute:Adult Hospital

Nicholas Manolios

Exploring the immune regulatory mechanisms in oral peanut immunotherapy for the treatment of peanut allergy

Email: [email protected]

Phone: 9845 3420

Institute:SCHN

Peter Hsu

Exploring the mechanism of immune dysregulation in primary immune deficiencies

Email: [email protected]

Phone: 9845 3420

Institute:SCHN

Peter Hsu

Understanding the pathogenesis of Food Protein Induced EnterocolitisSyndrome (FPIES)

Email: [email protected]

Phone: 9845 3420

Institute:SCHN

Peter Hsu

Influenza Vaccination: Fever, antipyretics and immunogenicity

Email: [email protected]

Phone: 0423 800 128

Institute:SCHN

Robert Booy

Page 20: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Corynebacterium diphtheriae: deciphering molecular mechanisms of virulence and antibiotic resistance

Email: [email protected]

Phone: 9845 6255

Institute:ICPMR

Vitali Sintchenko

Deciphering transmission networks of genital Chlamydia using genomics

Email: [email protected]

Phone: 9845 6255

Institute:ICPMR

Vitali Sintchenko

Finding the link between the environment and the patient -environmental sampling and phylogenetic studies with the artificial genus CandidaEmail: [email protected]

Phone: 8627 3430

Institute:WIMR

Wieland Meyer

Human Papilloma Virus (HPV) vaccine: long term protection

Email: [email protected]

Phone: 0423 800 128

Institute:SCHN

Robert Booy

Meningococcal disease: evolving epidemiology and provoking microbe elimination

Email: [email protected]

Phone: 0423 800 128

Institute:SCHN

Robert Booy

Surviving meningococcal disease: long term physical, psychological and economic implications

Email: [email protected]

Phone: 0423 800 128

Institute:SCHN

Robert Booy

Delineating the role of turnover rates and T cell activation in maintaining the latent HIV reservoir during effective antiretroviral therapy Email: [email protected]

Phone: 8627 3620

Institute:WIMR

Sarah Palmer

Page 21: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Molecular epidemiology of chlamydiosis in koalas in Gunnedah, New South Wales

Email: [email protected]

Phone: 8627 3430

Institute:WIMR

Wieland Meyer

Next generation sequencing applied to DNA barcoding of human pathogenic fungi

Email: [email protected]

Phone: 8627 3430

Institute:WIMR

Wieland Meyer

MLST applied to Pneumocystis jirovecii strain typing

Email: [email protected]

Phone: 8627 3430

Institute:WIMR

Wieland Meyer

NeurosciencesDetecting MOG-specific B cells in children with brain myelin diseases

Email: [email protected]

Phone: 9845 1456

Institute:SCHN

Fabienne Brilot-Turville

Understanding the role of T cells in autoantibody-associated movement and psychiatric disorders

Email: [email protected]

Phone: 9845 1456

Institute:SCHN

Fabienne Brilot-Turville

Fungal Microbiome of beach sands - a clinical connection?

Email: [email protected]

Phone: 8627 3430

Institute:WIMR

Wieland Meyer

Correlation between Genotype and Virulence of a New Super Killer; Cryptococcus neoformans and Cryptococcus gattii

Email: [email protected]

Phone: 8627 3430

Institute:WIMR

Wieland Meyer

Page 22: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Cortical processes underlying generation of intracortical inhibition and facilitation in healthy humans and ALS patients

Email: [email protected]

Phone: 9845 6097

Institute:Adult Hospital

Steve Vuvic

Mapping the molecular mechanisms of synapses using proteomics and cell biology

Email: [email protected]

Phone: 8865 2989

Institute:CMRI

Mark Graham

Brain plasticity using tDCS in healthy controls and neurodegenerative diseases Email: [email protected]

Phone: 9845 6097

Institute:Adult Hospital

Steve Vuvic

Nerve dysfunction in amyloid related neuropathy. Towards a biomarker of disease progression Email: [email protected]

Phone: 9845 6097

Institute:Adult Hospital

Steve Vuvic

Cortical dysfunction in ALS. Utilising novel MRI imaging and analytical techniquesEmail: [email protected]

Phone: 9845 6097

Institute:Adult Hospital

Steve Vuvic

Studying genetic muscle disease with CRISPR/Cas9 gene editing

Email: [email protected]

Phone: 9845 1444

Institute:SCHN

Fran Evesson

Understanding the emergency cell survival mechanism of membrane repairEmail: [email protected]

Phone: 9845 1441

Institute:SCHN

Frances Lemckert

Page 23: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Role of vitamin D in acute liver damage

Email: [email protected]

Phone: 9845 8089

Institute:WIMR

Jenny Gunton

Gene therapy for diabetes

Email: [email protected]

Phone: 9848 6305

Institute:Adult Hospital

Nicholas Manolios

Repair and regeneration of the injured heart

Email: [email protected]

Phone: 9845 6795

Institute:WIMR

James Chong

Characterisation of viral vectors targeting gap junctions: Toward gene therapy of cardiac arrhythmiasEmail: [email protected]

Phone: 8627 3670

Institute:WIMR

Eddy Kizana

Obesity/Diabetes

Muscle stem cells and vitamin D

Email: [email protected]

Phone: 9845 8089

Institute:WIMR

Jenny Gunton

Beige fat and obesity treatment

Email: [email protected]

Phone: 9845 8089

Institute:WIMR

Jenny Gunton

PhysiologyCardiology

Motor neuron disease phenotypes in ALS. Pathophysiological insights using transcranial magnetic stimulation and MRI techniques

Email: [email protected]

Phone: 9845 6097

Institute:Adult Hospital

Steve Vuvic

Page 24: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Exploring the genetic architecture of organ fibrosis

Email: [email protected]

Phone: 8627 3530

Institute:WIMR

Jacob George

Liver

Gene discovery in a cohort of paediatric bone fragility disorders

Email: [email protected]

Phone: 9845 0221

Institute:SCHN

Andrew Biggin

Optimising recombinant AAV (rAAV) production using the Insect/Baculoviral system.

Email: [email protected]

Phone: 8627 3670

Institute:WIMR

Eddy Kizana

Promoter optimisation for targeted cardiac gene therapy

Email: [email protected]

Phone: 8627 3670

Institute:WIMR

Eddy Kizana

Understanding the functional mechanisms of tissue fibrosis risk variants

Email: [email protected]

Phone: 8627 3530

Institute:WIMR

Jacob George

Exploring the role of epigenetic factors modulating the predisposition to tissue scarring (fibrosis) and cancer

Email: [email protected]

Phone: 8627 3530

Institute:WIMR

Jacob George

Bone

Development of strategies to protect against cardiotoxicity resulting from anti-cancer drugs

Email: [email protected]

Phone: 8627 3670

Institute:WIMR

Eddy Kizana

Page 25: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Investigating parents’ experiences communicating with their child’s doctor about the online health information they find on their child’s medical conditionEmail: [email protected]

Phone: 9845 3385

Institute:SCHN

Karen Scott

Glomerular Podocyte Injury and Repair Mechanisms

Email: [email protected]

Phone: Institute:SCHN

Yuan Wang

Studying the effects of genetic mutations on musculoskeletal tissue function

Email: [email protected]

Phone: 9845 1451

Institute:SCHN

Aaron Schindeler

Gene therapy for bone diseases

Email: [email protected]

Phone: 9845 1451

Institute:SCHN

Aaron Schindeler

Serum analysis of circulating drugs by mass spectrometry (MS)

Email: [email protected]

Phone: 9845 1451

Institute:SCHN

Aaron Schindeler

Osteogenic differentiation of iPS cells generated from peripheral blood Email: [email protected]

Phone: 9845 1451

Institute:SCHN

Aaron Schindeler

Renal

Public Health

Building bone strength in brittle bone disease

Email: [email protected]

Phone: 9845 1451

Institute:SCHN

Aaron Schindeler

Page 26: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

HPV school based vaccination of adolescence

Email: [email protected]

Phone: 9845 3377

Institute:SCHN

Rachel Skinner

Establishing the risk factor profile of patients with late-stage age-related macular degeneration (AMD)

Email: [email protected]

Phone: 8627 3368

Institute:WIMR

Bamini Gopinath

‘Caring for the Carer': implementing a comprehensive support service model for family caregivers looking after persons with age-related macular degeneration

Email: [email protected]

Phone: 8627 3368

Institute:WIMR

Bamini Gopinath

Adolescence, risk-taking and sexual health

Email: [email protected]

Phone: 9845 3377

Institute:SCHN

Rachel Skinner

Page 27: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

What to do next...

Want more information on a project/supervisor?Contact the supervisor or the Honours Coordinator to find out more about the project. Additional information is available at http://sydney.edu.au/medicine/study/honours/westmead/, including brief overviews of projects and previous work our supervisors have undertaken. While you’re there you can also use the search tool to look for other projects of interest offered at Westmead.

Found a project/supervisor you’re interested in?Contact your potential supervisor directly (usually via email) and request a time for a meeting. It’s extremely important you meet with your potential supervisor in person before applying for their project, both for you and the supervisor. It is also useful to include a scanned copy of your academic transcript and CV and a bit about yourself and why you’re interested in the offered project.

Following the meeting if you are interested in undertaking the project, and the supervisor is willing to accept you for the project, then you can proceed to make an application. Fill out and submit an expression of interest form available from your potential supervisor or the Honours Coordinator (Andrew Harman) and keep working hard to ensure you obtain the required SCIWAM of 68.

Eligible for a scholarship?A number of scholarships are available for honours students each year. These include:

§ Westmead Interstate scholarship $10,00§ Westmead NSW & ACT $5,000§ USYD honours scholarships $6,000

For more information on scholarships visit:http://sydney.edu.au/science/fstudent/undergrad/honours_scholarships.shtml

Page 28: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

The Children’s Medical Research Institute (CMRI) has been pioneering microsurgery, immunisations against lethal childhood illnesses, and care for premature babies, improving the lives of countless Australian children for 50 years. Today, the CMRI is the site of world-leading research in areas such as cancer, neurobiology, embryology and gene therapy. CMRI Honours Coordinator: Mark Graham; [email protected]

Institutes and Research Partners

The Institute for Clinical Pathology and Medical Research - NSW Health Pathology (ICPMR) is the largest research-active pathology service in the country and the leading national reference lab for infectious diseases, medical entomology and parasitology. In 2014–15, it contributed to initiatives that were awarded more than $47 million in competitive external grants, and co-authored nearly 400 publications. The ICPMR’s broad range of activities interfaces with all facets of research undertaken at Westmead, including facilitation of clinical trials, biobanking, electron microscopy, pathogen genomics and flow cytometry. ICMPR Honours Coordinator:David Brown; [email protected]

Page 29: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

The Institute of Dental Research (IDR) at the Westmead Centre for Oral Health is the oldest named dental institute in the world. Research at the Faculty of Dentistry and IDR embraces innovative research through broad themes of chronic diseases combined with a deeper understanding of the impact of oral health on the whole body. The IDR’s research strengths include microbial pathogenicity, bioengineering and mucosal pathologies. IDR Honours coordinator:Joerg Eberhard; [email protected]

Institutes and Research Partners

The Kids Research Institute (KRI) has 300 researchers working with TheChildren’s Hospital at Westmead (CHW), the biggest children’s hospital in NSW and part of The Sydney Children's Hospital Network (SCHN) . KRI’s research improves the lives of children with debilitating illnesses through discovery and translational research in cancer, bone diseases, genetic conditions, diabetes, obesity, infectious diseases, brain and muscle disorders, rare genetic and immunological diseases, sleep disorders, and kidney and liver disease. KRI/SCHN Honours Coordinators:Fabienne Brilot-Turville; [email protected] Fran Evesson; [email protected]

Page 30: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

Westmead Hospital is a major teaching hospital of the University of Sydney for allied health, dental, medical and nursing students, and is one of Australia’s largest centres for postgraduate training at specialist level in all health fields. Westmead Hospital conducts biomedical, clinical and public health research in hospital-based centres and departments. As such, their research covers a broad spectrum including, but not limited to, laboratory, drug and device trials, and epidemiological studies. Honours Coordinator: Heather Medbury [email protected]

The Westmead Institute for Medical Research is one of the largest medical research facilities in Australia. It is home to more than 300 scientists and students who are using the essential tools of molecular and cell biology, plus new techniques in gene discovery, genetic epidemiology, human and cell imaging technology, cell and gene therapy and clinical research. The institute undertakes diverse research spanning the laboratory to the patient, which has led to new medical treatment and prevention programs nationally, and changed health practice internationally. Honours coordinator: Najla Nasr [email protected]

Institutes and Research Partners

Page 31: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

More than just research

Peer Mentoring SchemeThe Westmead Honours program has implemented a peer mentoring scheme which pairs each Honours student with a PhD student or early post doctoral researcher from another lab. This gives each student an opportunity to talk to someone who has recently gone through the experience of Honours about their own experience and any challenges they might be having.

Honours Social NightsOnce a month the Honours Social Committee (HSoC), made up of honours students and mentors, hold an event to allow students to step out of the lab and have some fun. Previous events have included a welcome BBQ, Trivia nights, pizza dinners, board game nights and thesis submission celebrations. This has helped build a sense of community among the honours students working at Westmead, allowing students from across all the institutes to come together and get to know each other away from their studies.

Artist’s impression

Page 32: Honours in Applied Medical Science - University of Sydneysydney.edu.au/medicine/pdfs/Westmead-Honours... · Sydney. Science. Westmead. Honours in Applied Medical Science at Westmead

CRICOS 0026A

For more information

Applied Medical Science Honours CoordinatorAndrew HarmanT +61 2 8627 3623 | E [email protected]