HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71...

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Mercado Alternativo Bursátil Plaza de la Lealtad, 1 28014 Granada, a 29 de mayo de 2014 HECHO RELEVANTE NEURON BIOPHARMA, S.A. Muy Sres. Nuestros: En cumplimiento con lo dispuesto en la Circular 9/2010 del MAB sobre información a suministrar por empresas en expansión incorporadas a negociación en el MAB, por la presente se pone en conocimiento la siguiente información relativa a Neuron Biopharma, S.A. La Compañía ha participado en el 10º Foro Medcap de empresas de mediana capitalización, organizado por Bolsas y Mercados Españoles. Adjuntamos la presentación corporativa que se ha utilizado en dicho foro. Atentamente, D. Fernando Valdivieso Amate Presidente del Consejo de Administración

Transcript of HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71...

Page 1: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

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Mercado Alternativo Bursátil Plaza de la Lealtad, 1 28014

Granada, a 29 de mayo de 2014

HECHO RELEVANTE NEURON BIOPHARMA, S.A.

Muy Sres. Nuestros:

En cumplimiento con lo dispuesto en la Circular 9/2010 del MAB sobre información a suministrar por empresas en expansión incorporadas a negociación en el MAB, por la presente se pone en conocimiento la siguiente información relativa a Neuron Biopharma, S.A.

La Compañía ha participado en el 10º Foro Medcap de empresas de mediana capitalización, organizado por Bolsas y Mercados Españoles. Adjuntamos la presentación corporativa que se ha utilizado en dicho foro.

Atentamente,

D. Fernando Valdivieso Amate Presidente del Consejo de Administración

Page 2: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

1

Ma

dri

d

28

ma

yo

20

14

Page 3: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

Th

e c

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Cre

ati

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ith

Re

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uro

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cts

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Page 4: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

Str

uct

ure

: 2

00

6-2

01

3

3

Page 5: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

4

Mis

sio

n &

Vis

ion

Vis

ion

To

be

re

cog

niz

ed

as

an

in

tern

ati

on

al

refe

ren

ce i

n t

he

me

dic

al

bio

tech

no

log

y d

uri

ng

th

e n

ex

t fi

ve

ye

ars

Mis

sio

n

Cre

ati

on

, d

ev

elo

pm

en

t a

nd

ma

na

ge

me

nt

of

bio

tech

no

log

ica

l

com

pa

nie

s

fb

ih

li

l

Page 6: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

5

Ov

erv

iew

C

OM

PA

NY

PR

OF

ILE

: Q

uo

ted

on

th

e S

pa

nis

h A

lte

rna

tiv

e S

tock

Ma

rke

t (M

AB

) L

OC

AT

ION

S:

Gra

na

da

He

alt

h-S

cie

nce

Te

chn

olo

gy

Pa

rk (

he

ad

qu

art

ers

)

•M

ad

rid

Sci

en

ce P

ark

(la

bo

rato

ry, a

nim

al

faci

liti

es

& o

ffic

es)

B

US

INE

SS

LIN

ES

:

•D

rug

Dis

cov

ery

&D

eve

lop

me

nt

Dev

elo

pm

en

t o

f d

iag

no

stic

s to

ols

R&

D b

iose

rvic

es

MA

NA

GE

ME

NT

:

•U

NE

16

6.0

02

(S

tan

da

rd O

pe

rati

ng

Pro

ced

ure

fo

r R

&D

)

•S

GE

21

(E

thic

al a

nd

CS

R M

an

ag

em

en

t Sy

ste

m)

R&

D:

Mo

re t

ha

n 5

0 y

ea

rs o

f a

ccu

mu

late

d p

ost

do

cto

ral

ex

pe

rie

nce

in

R&

D

•P

art

icip

ati

on

in

15

sci

en

tifi

c p

roje

cts

•P

rop

ert

y o

f a

wid

e c

oll

ect

ion

of

mo

lecu

les

(ne

w c

he

mic

al

en

titi

es

an

d r

ep

rofi

lin

g d

rug

s)

an

d n

atu

ral

pro

du

cts

(>2

0.0

00

pla

nt

an

d m

icro

bia

l ex

tra

cts)

Ov

er €

10

mil

lio

n s

o f

ar

inv

est

ed

in

R&

D

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6

Str

en

gh

ts

TE

AM

: 2

3 p

eo

ple

on

th

e s

taff

, 1

0 o

f th

em

do

cto

rs,

a B

oar

d o

f D

irec

tors

wit

h w

ide

bu

sin

ess

ex

pe

rie

nce

an

d a

n i

nte

rna

tio

na

lly

re

cog

niz

ed

sci

en

tifi

c a

dv

iso

ry b

oa

rd

TE

CH

NO

LO

GY

: E

xclu

sive

Dru

g D

isco

ve

ry &

De

ve

lop

me

nt

Pla

tfo

rm c

on

sist

ing

in:

• A

Scr

ee

nin

g P

latf

orm

to

id

en

tify

po

ten

tia

l n

eu

rop

rote

ctiv

e c

an

did

ate

s (h

igh

-th

rou

gh

pu

t te

chn

olo

gie

s)

• A

Pre

clin

ica

l P

latf

orm

to

se

lect

th

e b

ett

er

in v

ivo

ca

nd

ida

te a

nd

pe

rfo

rm i

ts d

ev

elo

pm

en

t a

nd

op

tim

iza

tio

n

• M

ore

th

an

50

dif

fere

nt

tech

no

log

ies

incl

ud

ing

in

sil

ico

, in

vit

ro a

nd

ce

llu

lar

ass

ays

as

we

ll a

s a

nim

al

mo

de

ls

• E

ffic

acy

, sa

fety

an

d p

ha

rma

cok

ine

tics

M

AR

KE

TS

: G

lob

al

Ce

ntr

al

Ne

rvo

us

Sy

ste

m (

CN

S)

ma

rke

t: $

71

bil

lio

n i

n 2

01

0

•N

eu

rod

eg

en

era

tiv

e d

iso

rde

rs m

ark

et:

>$

21

bil

lio

n i

n 2

00

9

•A

lzh

eim

er’

s d

ise

ase

(A

D):

$8

bil

lio

n i

n 2

00

9 a

nd

$9

.6 b

illi

on

in 2

01

4 (

exp

ect

ed

) •

Dru

gs

ag

ain

st A

D:

>$

4.2

bil

lio

n i

n 2

01

2

•D

iag

no

stic

to

ols

ag

ain

st A

D:

$1

.2 b

illi

on

in

20

09

an

d $

2.9

bil

lio

n i

n 2

01

4 (

exp

ect

ed

) G

lob

al

R&

D s

erv

ice

s m

ark

et:

$8

5-1

05

bil

lio

n i

n 2

01

3

•N

on

-cli

nic

al r

ese

arc

h m

ark

et:

$1

1-1

5 b

illi

on

in

20

13

Page 8: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

7

Ho

ldin

g s

tru

ctu

re:

20

14

Mis

sio

n:

Tra

de

r in

Eu

rop

e a

nd

in t

he

re

st o

f th

e

wo

rld

Mis

sio

n:

Dis

cove

ry o

f

ne

uro

pro

tect

an

ts

Mis

sio

n:

De

velo

pm

en

t

of

dia

gn

ost

ic t

oo

ls

Mis

sio

n:

De

velo

pm

en

t

of

bio

pro

cess

es

Mis

sio

n:

Cre

ati

on

, d

eve

lop

me

nt

an

d m

an

ag

em

en

t o

f

bio

tech

co

mp

an

ies

Page 9: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

8

1. C

OM

PA

NY

PR

OF

ILE

2. M

ISS

ION

3. O

PP

OR

TU

NIT

Y D

ES

CR

IPT

ION

4. S

OL

UT

ION

PR

OP

OS

AL

5. K

EY

DIF

FE

RE

NT

IAL

ST

RA

TE

GY

6. B

US

INE

SS

RIS

K

DIV

ER

SIF

ICA

TIO

N &

CO

NT

ING

EN

CY

S

TR

AT

EG

IES

:

7. B

US

SIN

ES

S M

OD

EL

8. N

EX

T S

TE

PS

Page 10: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

9

1. C

OM

PA

NY

PR

OF

ILE

: P

ub

lic

com

pa

ny

qu

oti

ng

on

th

e S

pa

nis

h A

lte

rna

tiv

e S

tock

Ma

rke

t (M

AB

) 2

. MIS

SIO

N:

Cre

ati

on

, de

velo

pm

en

t a

nd

ma

na

ge

me

nt

of

bio

tech

co

mp

an

ies

3. O

PP

OR

TU

NIT

Y D

ES

CR

IPT

ION

:

•T

he

glo

ba

l b

iote

chn

olo

gy

ma

rke

t in

20

16

is

fore

cast

to

hav

e a

va

lue

of

>$

45

0 b

illi

on

* •

Me

dic

al/

he

alt

hca

re i

s th

e l

arg

est

se

gm

en

t o

f th

e g

lob

al

bio

tech

no

log

y m

ark

et

(67

%)*

Am

eri

cas

acc

ou

nts

fo

r 4

5%

of

the

glo

ba

l b

iote

chn

olo

gy

ma

rke

t va

lue*

4. S

OL

UT

ION

PR

OP

OS

AL

:

•N

eu

ron

Bio

ha

s b

ee

n s

pe

cia

lize

d i

n t

he

la

st y

ea

rs i

n t

he

bio

tech

ma

rke

t, g

en

era

tin

g

an

d d

eve

lop

ing

ne

w c

om

pa

nie

s w

ith

an

in

cre

asi

ng

va

lue

*Biotechnology: Global Industry Guide

Page 11: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

10

5. K

EY

DIF

FE

RE

NT

IAL

ST

RA

TE

GY

:

•H

yb

rid

str

ate

gy

(se

rvic

es

for

clie

nts

an

d g

en

era

tio

n o

f va

lue

fo

r st

ak

eh

old

ers

) •

Ho

ldin

g s

tru

ctu

re w

ith

se

ve

ral

com

pa

nie

s in

th

e g

rou

p

6. B

US

INE

SS

RIS

K D

IVE

RS

IFIC

AT

ION

& C

ON

TIN

GE

NC

Y S

TR

AT

EG

IES

:

•D

ive

rsit

y i

n t

he

bu

sin

ess

lin

es

•C

ap

aci

ty t

o g

en

era

te n

ew

bu

sin

ess

7. B

US

SIN

ES

S M

OD

EL

:

•S

ale

of

pa

rtic

ipa

tio

ns

of

the

su

bsi

dia

ry c

om

pa

nie

s •

Ex

plo

ita

tio

n o

f th

e N

eu

ron

Bio

fa

cili

tie

s a

nd

la

bo

rato

rie

s •

Sa

le o

f se

rvic

es

for

clie

nts

Co

-de

ve

lop

me

nts

wit

h s

tra

teg

ic p

art

ne

rs

8. N

EX

T S

TE

PS

:

1)

To

mo

ve t

o t

he

ne

w h

ea

dq

ua

rte

rs (

6 m

on

ths)

2

) T

o r

ea

ch t

he

fu

nd

ing

fo

r th

e s

ub

sid

iary

co

mp

an

ies

(12

mo

nth

s)

3)

To

in

cre

ase

th

e v

isib

ilit

y o

f th

e g

rou

p (

12

mo

nth

s)

Page 12: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

11

1. P

RO

FIL

E

2. M

ISS

ION

3. O

PP

OR

TU

NIT

Y D

ES

CR

IPT

ION

4. S

OL

UT

ION

PR

OP

OS

AL

5. B

US

INE

SS

MO

DE

L

Page 13: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

1. P

RO

FIL

E:

Ne

uro

n B

io t

rad

em

ark

to

co

mm

erc

iali

ze R

&D

bio

serv

ice

s

2. M

ISS

ION

: T

o o

ffe

r in

teg

rate

d p

recl

inic

al

solu

tio

ns

for

ph

arm

ace

uti

cal,

bio

tech

no

log

y a

nd

ag

ro-f

oo

d c

om

pa

nie

s 3

. OP

PO

RT

UN

ITY

DE

SC

RIP

TIO

N:

•T

he

glo

ba

l m

ark

et

for

dru

g d

isco

very

& d

eve

lop

me

nt

is o

ver

$8

5 b

illi

on

Th

e m

ain

th

era

pe

uti

c m

ark

ets

are

au

toim

mu

ne

dis

ea

ses,

Ce

ntr

al

Ne

rvo

us

Syst

em

, ca

rdio

vasc

ula

r, i

nfe

ctio

n, o

be

sity

an

d o

nco

log

y

•In

20

10

, th

e U

S n

utr

ace

uti

cal

ma

rke

t st

oo

d a

t $

50

.4 b

illi

on

an

d w

as

by

fa

r th

e l

arg

est

n

utr

ace

uti

cal

ma

rke

t in

th

e w

orl

d

12

Page 14: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

13

4. S

OL

UT

ION

PR

OP

OS

AL

:

•A

n e

xclu

sive

Scr

ee

nin

g &

Pre

clin

ica

l P

latf

orm

to

stu

dy

eff

ica

cy, s

afe

ty a

nd

p

ha

rma

cok

ine

tics

of

mo

lecu

les,

ex

tra

cts,

in

gre

die

nts

, an

d n

atu

ral

pro

du

cts

•M

ore

th

an

50

dif

fere

nt

tech

no

log

ies

incl

ud

ing

in silico

, in vitro

, ce

llu

lar

ass

ays

an

d

an

ima

l m

od

els

(ze

bra

fish

an

d r

od

en

ts)

l

mo

de

ls (

zeb

rafi

sha

nd

ro

de

nts

)

Yo

ur in

teg

rate

d s

olu

tio

n fo

r

hig

h-q

uality

pre

-clin

ica

l s

tud

ies

on

the

rig

ht p

ath

to

wa

rds

a re

gu

lato

ry a

ge

nc

y a

pp

rova

l

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14

5.

BU

SS

INE

SS

M

OD

EL

: O

ffe

r so

luti

on

s to

a

gro

foo

d,

bio

tech

a

nd

p

ha

rma

com

pa

nie

s in

tw

o d

iffe

ren

t b

usi

ne

ss l

ine

s:

•R

&D

Se

rvic

es:

eff

ica

cy, s

afe

ty, p

ha

rma

cok

ine

tics

&p

ha

rma

cod

yn

am

ics,

g

en

era

tio

n o

f ex

pe

rim

en

tal

mo

de

ls, e

tc.

•C

on

sult

ing

: m

an

ag

em

en

t, l

ab

ora

tory

de

sig

n, t

rain

ing

, co

mm

un

ica

tio

n,

ind

ust

ria

l p

rop

ert

y, f

un

dra

isin

g, e

tc.

Page 16: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

1. C

OM

PA

NY

PR

OF

ILE

2. M

ISS

ION

3. O

PP

OR

TU

NIT

Y D

ES

CR

IPT

ION

4. S

OL

UT

ION

PR

OP

OS

AL

5. K

EY

DIF

FE

RE

NT

IAL

ST

RA

TE

GY

6. B

US

INE

SS

RIS

K D

IVE

RS

IFIC

AT

ION

& C

ON

TIN

GE

NC

Y

ST

RA

TE

GIE

S:

7. B

US

SIN

ES

S M

OD

EL

8. N

EX

T S

TE

PS

15

Page 17: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

16

1. C

OM

PA

NY

PR

OF

ILE

: P

riva

te c

om

pa

ny

2. M

ISS

ION

: D

isco

very

an

d d

eve

lop

me

nt

of

com

po

un

ds

for

pre

ven

tio

n o

r tr

ea

tme

nt

of

ne

uro

de

ge

ne

rati

ve a

nd

ce

ntr

al

ne

rvo

us

syst

em

dis

ea

ses

3. O

PP

OR

TU

NIT

Y D

ES

CR

IPT

ION

:

•M

ore

th

an

44

mil

lio

n p

eo

ple

su

ffe

r fr

om

ne

uro

de

ge

ne

rati

ve d

iso

rde

rs

•T

he

glo

ba

l e

con

om

ic c

ost

fo

r A

lzh

eim

er´

s d

ise

ase

(A

D)

is $

64

0 b

illi

on

Th

e d

rug

ma

rke

t fo

r A

D e

xce

ed

ed

$4

.2 b

illi

on

in

20

12

Th

ere

are

no

t e

ffe

ctiv

e t

rea

tme

nts

ag

ain

st A

D

Page 18: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

17

PR

OD

UC

TT

YP

EO

F M

OLE

CU

LET

HE

RA

PE

UT

IC

AR

EA

IND

ICA

TIO

NS

CR

EE

NIN

GE

FF

ICA

CY

RE

GU

LAT

OR

YP

HA

SE

I

NS

T0

03

7

NS

T0

06

0

Sta

tin

de

riv

ati

ve

s

CN

S

CN

S

MC

I

MC

I

NS

T0

07

6

NS

T0

07

8

NP

S0

16

3

3rd

-ge

ne

rati

on

ne

uro

pro

tect

ive

mo

lecu

les

Xa

nto

cill

in

de

riv

ati

ve

CN

S

CN

S

CN

S

MC

I

MC

I

MC

I

NS

T P

roje

cts

NP

S, S

CR

an

d X

AN

Pro

ject

s

NS

T P

roje

cts

4. S

OL

UT

ION

PR

OP

OS

AL

:

•R

ese

arc

h f

ocu

sed

on

ce

ntr

al

ne

rvo

us

syst

em

dis

ea

ses,

ma

inly

AD

Aim

ing

at

inn

ov

ati

ve

ta

rge

ts d

iffe

ren

t fr

om

cla

ssic

al

on

es

(β-a

my

loid

) •

Dev

elo

pm

en

t o

f n

eu

rop

rote

cta

nts

A

Pip

eli

ne

w

ith

5

n

ove

l a

nd

p

ate

nte

d

ne

uro

pro

tect

ive

co

mp

ou

nd

s a

ga

inst

e

arl

y

sta

ge

s o

f A

lzh

eim

er’

s d

ise

ase

, an

d b

elo

ng

ing

to

th

ree

gro

up

s o

f m

ole

cule

s:

Page 19: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

18

5. K

EY

DIF

FE

RE

NT

IAL

ST

RA

TE

GY

TO

AD

DR

ES

S A

LZ

HE

IME

R´S

DIS

EA

SE

:

•D

eve

lop

me

nt

of

mo

lecu

les

wit

h m

ore

th

an

on

e m

ech

an

ism

-of-

act

ion

Se

arc

h f

or

dis

ea

se-m

od

ifie

r th

era

pie

s fo

cuse

d o

n t

he

ea

rly

sta

ge

s o

f th

e d

ise

ase

Tra

nsl

ati

on

al

rese

arc

h t

o r

ed

uce

att

riti

on

in

cli

nic

al

tria

ls

•Id

en

tifi

cati

on

of

no

ve

l m

ech

an

ism

s o

f n

eu

rop

rote

ctio

n t

o d

esi

gn

ne

w t

he

rap

eu

tic

stra

teg

ies

6. B

US

INE

SS

RIS

K D

IVE

RS

IFIC

AT

ION

& C

ON

TIN

GE

NC

Y S

TR

AT

EG

IES

:

•D

ive

rsit

y i

n t

he

dru

g p

ipe

lin

e

•A

vail

ab

ilit

y o

f b

ack

-up

mo

lecu

les

in e

ach

ph

arm

aco

log

ica

l g

rou

p

•D

eve

lop

me

nt

of

ne

uro

pro

tect

ive

co

mp

ou

nd

s a

ime

d a

t d

iffe

ren

t n

eu

rolo

gic

al

dis

ord

ers

, no

t o

nly

AD

Mo

lecu

les

wit

h a

dd

itio

na

l p

rop

ert

ies

to n

eu

rop

rote

ctio

n

•F

ea

sib

le i

de

nti

fica

tio

n o

f n

ew

ca

nd

ida

tes

an

d e

asi

ly a

nd

fa

st p

recl

inic

al

de

velo

pm

en

t

Page 20: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

19

7. B

US

SIN

ES

S M

OD

EL

:

•S

ale

of

exp

loit

ati

on

lic

en

ses

for

the

ne

uro

pro

tect

ive

co

mp

ou

nd

s

•S

ale

of

use

an

d e

xp

loit

ati

on

lic

en

ses

for

the

Dru

g D

isco

ve

ry &

De

ve

lop

me

nt

pla

tfo

rm

an

d c

om

po

un

d e

valu

ati

on

8

. NE

XT

ST

EP

S:

1)

NS

T0

03

7 p

ha

se I

(1

2 m

on

ths)

2

) R

eg

ula

tory

pre

clin

ica

l st

ud

ies

of

NS

T0

07

6 o

r N

ST

00

78

(1

8 m

on

ths)

3

) P

recl

inic

al

eff

ica

cy s

tud

ies

of

NP

S0

16

3 (

16

mo

nth

s)

Page 21: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

20

Page 22: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

1. C

OM

PA

NY

PR

OF

ILE

2. M

ISS

ION

3. O

PP

OR

TU

NIT

Y D

ES

CR

IPT

ION

4. S

OL

UT

ION

PR

OP

OS

AL

5. K

EY

DIF

FE

RE

NT

IAL

ST

RA

TE

GY

6. B

US

INE

SS

RIS

K D

IVE

RS

IFIC

AT

ION

& C

ON

TIN

GE

NC

Y

ST

RA

TE

GIE

S

7. B

US

SIN

ES

S M

OD

EL

21

Page 23: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

22

1. C

OM

PA

NY

PR

OF

ILE

: P

riva

te c

om

pa

ny

2. M

ISS

ION

: D

eve

lop

me

nt

of

dia

gn

ost

ic a

nd

pro

gn

ost

ic t

oo

ls f

or

hu

ma

n d

ise

ase

s

wit

h e

spe

cia

l fo

cus

to n

eu

rolo

gic

al/

ne

uro

de

ge

ne

rati

ve d

iso

rde

rs

3. O

PP

OR

TU

NIT

Y D

ES

CR

IPT

ION

:

•T

he

re a

re a

un

me

t d

iag

no

stic

ne

ed

s fo

r se

vera

l h

um

an

dis

ea

ses,

esp

eci

all

y i

n t

he

n

erv

ou

s d

iso

rde

rs s

uch

as

the

Alz

he

ime

r´s

dis

ea

se (

AD

)

•D

iag

no

stic

/b

iom

ark

ers

is

the

2n

d-l

arg

est

se

gm

en

t o

f th

e A

D-m

ark

et

($2

.9 b

illi

on

in

2

01

4)

4. S

OL

UT

ION

PR

OP

OS

AL

:

•D

eve

lop

me

nt

a n

ov

el

dia

gn

ost

ic t

oo

l fr

om

ea

rly

sta

ge

s o

f A

D

•D

iag

no

stic

to

ol

tha

t w

ill

ide

nti

fy i

nd

ivid

ua

ls w

ith

hig

h r

isk

to

de

velo

p A

D

Page 24: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

23

5. K

EY

DIF

FE

RE

NT

IAL

ST

RA

TE

GY

TO

AD

DR

ES

S A

LZ

HE

IME

R´S

DIS

EA

SE

:

•F

ocu

sed

in

th

e d

iscr

imin

ati

on

of

ind

ivid

ua

ls w

ith

MC

I, A

D, o

r h

ea

lth

y

•M

inim

all

y i

nv

asi

ve

sa

mp

le c

oll

ect

ion

Co

mb

ina

tio

n o

f b

iolo

gic

al

flu

ids

(sa

liva

, blo

od

…)

•B

iom

ark

er-

ba

sed

to

ol

on

va

rio

us

me

cha

nis

ms-

of-

act

ion

6. B

US

INE

SS

RIS

K D

IVE

RS

IFIC

AT

ION

& C

ON

TIN

GE

NC

Y S

TR

AT

EG

IES

:

•A

dd

itio

na

l a

pp

roa

che

s to

ex

pa

nd

th

e r

an

ge

of

bio

ma

rke

rs t

o a

na

lyze

Ide

nti

fica

tio

n o

f b

iom

ark

er

for

oth

er

de

me

nti

as

To

off

er

dia

gn

ost

ics

serv

ice

s u

sin

g o

ur

bio

ma

rke

r a

na

lysi

s p

latf

orm

an

d m

ed

ica

l n

etw

ork

7

. BU

SS

INE

SS

MO

DE

L:

Sa

le o

f ex

plo

ita

tio

n l

ice

nse

s fo

r th

e d

iscr

imin

ato

ry t

oo

l fo

r:

•B

ig P

ha

rma

Co

mp

an

ies

•D

iag

no

stic

s C

om

pa

nie

s

Page 25: HECHO RELEVANTE NEURON BIOPHARMA, S.A. · MARKETS: Global Central Nervous System (CNS) market: $71 billion in 2010 • Neurodegenerative disorders market: >$21 billion in 2009 •

24

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