Falls Prevention for SPRs Feb 07

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    Falls and fracture prevention

    Dr Nicki Colledge

    Liberton Hospital and

    Royal Infirmary, Edinburgh

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    Why are falls important?

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    High incidence:

    30% of those over 65 report a fall each year Rises to 60% of those in care homes

    Sometimes fatal: 85% of deaths due to accidents at home are caused by

    falls in those over 65 Injuries are frequent:

    Falls cause 1 million non-fatal injuries per year

    Psychological impact:

    Fear of falling is the most frequent reason given for amove to a care home

    Expensive: 909 million p.a. to the NHS

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    Falls and fractures

    Type of fracture Percentage attributed to

    falls by older women

    Wrist

    Proximal humerusHip

    Ankle

    Pelvis

    Face

    Tibia/fibula

    Face

    Vertebral

    96

    9592

    88

    80

    77

    65

    59

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    Osteoporosis

    >300,000 osteoporotic fracturesp.a.

    Estimated costs = 1.7 billion/year

    47, 471 hip fractures p.a. 90% occur in people aged over 50

    40% die within the next year

    Estimated cost of treatment and care:7.26million/year

    Cost to the individual: 80% of womenaged over 75 would rather die than havea hip fracture that led to admission to anursing home

    Normal bone

    Osteoporotic bone

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    Why are old people so prone to falls?

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    Balance and Ageing: reaction times

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    Lawlor, D. A et al. BMJ 2003;327:712-717

    Annual prevalence of falls in older women andnumber of simultaneous chronic diseases

    Chronic diseases included

    e.g. circulatory disease,

    depression, and arthritis

    Crude data adjusted for age,

    each drug taken, BMI, alcohol

    consumption, Hb concentration

    and social class

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    Who is at risk of falling?

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    Risk factors for falls

    Risk factor Relative risk ratio/Oddsratio

    Muscle weakness

    History of falls

    Gait deficit

    Balance deficitWalking aid use

    Visual deficit

    Arthritis

    Impaired ADL

    DepressionCognitive impairment

    Psychoactive drugs

    Age >80

    4.4

    3.0

    2.9

    2.92.6

    2.5

    2.4

    2.3

    2.21.8

    1.7

    1.7

    AGS et al. J Amer Geriatr Soc 2001

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    Cardiovascular disease and falls

    Increased prevalence of falls in those with: Intermittent claudication

    Post-prandial hypotension

    Lower standing systolic blood pressure

    Overlap between symptoms of falls and syncope

    Causal association identified with

    Postural hypotension Carotid sinus syndrome

    Vasovagal syndrome

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    Environmental hazards

    A third to a half of falls are due to environmental factorse.g. inappropriate footwear and walking aids

    Falls cannot be predicted from the number of hazardspresent

    Trips often occur on objects not assessed as hazardous

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    Falls risk factors increase the risk of fracture

    Independent risk factors for # in those over 75 years:

    Nguyen et al. BMJ 1993

    EPIDOS study. Lancet,1996

    muscle strength

    postural sway

    visual impairment

    neuromuscular impairments

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    Can falls (and fractures) be prevented?

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    PROFET :Preventing falls in patients presenting to A&E

    Patients aged > 65 attending A & E with a fall

    184 randomised to medical and Occupational Therapy assessment

    213 controls

    Medical assessment and treatment of cause of fall

    72% balance impairment

    59% visual impairment

    34% cognitive impairment

    28% reduced muscle power

    20% peripheral neuropathy

    17% cardiovascular disorders

    OT home visit: safety education and environmental adaptations

    Close et al, Lancet 1999

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    PROFET: results

    12 months later:

    183 falls in intervention group

    510 falls in controls (p=0.0002)

    Outcome Odds ratio (95% C.I.)

    Reduction in any fall 0.39 (0.23-0.66)

    Reduction in recurrent falls 0.33 (0.16-0.68)

    Reduction in hospital admission 0.61 (0.35-1.05)

    Close, J et al. Lancet 1999;353:93

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    Effective interventions for falls prevention

    Cochrane Review Update 2004

    1.Multidisciplinary, multifactorial risk factor screening and

    interventionPopulation RR 95% C.I.

    Unselected 0.73 0.63-0.85

    History of falls or risk factors 0.86 0.76-0.98

    In Residential care 0.60 0.50-0.73

    Gillespie LD et al, The Cochrane Library, Issue 3, 2004.

    Oxford Update Software. (www.cochrane.co.uk)

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    Effective interventions

    2. Muscle strengthening and balance retraining

    Individually prescribed

    Delivered in patients home by a health professional

    RR 0.80 (95% C.I. 0.66-0.98)

    3.Home hazard assessment and modification Professionally prescribed

    In those who have fallen (only)RR 0.66 (95% C.I. 0.54-0.81)

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    Effective interventions

    4. Withdrawl of psychotropic medication

    RR 0.34 (95% CI 0.16-0.74)

    5. Cardiac pacing for fallers with Carotid Sinus SyndromeWMD -5.20 (95% CI -9.4- -1.0)

    6. Tai Chi group exercise intervention

    RR 0.51 (95% CI 0.36-0.73)

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    Cataract surgery and falls

    RCT of expedited cataract surgery (approx 4 weeks) vsroutine wait (12 months)

    306 women aged >70 randomised

    Rate of falling: reduced by 34% in the early surgerygroup after 12 months (p

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    NICE guideline 21 : Assessment and

    prevention of falls in older people

    Key priorities

    Case/risk identification

    Multifactorial Falls risk assessment Multifactorial interventions

    Encouraging older people to participate in these

    Professional education

    National Institute for Clinical Excellence

    NICE.gov.uk

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    Gait, balance

    and mobility

    Visual

    impairment

    Cognitive

    impairment

    Cardiovascularexamination

    Osteoporosis risk

    Urinary

    continence

    Neurological

    examination

    Functional ability/

    fear of falling

    Medication

    review

    Falls history

    Multifactorial

    assessment

    NICE guideline21

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    Multifactorial intervention

    Individualised to patient according to diagnosis,causes and risk factors

    Most successful programmes include:

    Strength and balance training

    Home hazard assessment and intervention

    Vision assessment and referral

    Medication review and modification

    NICE guideline 21

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    Applying the guidelines to the individual

    Treat any acute illness that precipitated the fall

    Treat specific conditions affecting balance

    e.g Parkinsons disease, osteoarthrosis, stroke

    Correct postural hypotension or arrhythmia

    Rationalise medication especially psychotropic agents

    Correct visual impairment where possible

    Physiotherapy: balance and strength training

    OT: environmental hazard check, safety awareness

    Commence osteoporosis treatment where indicated

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    Treatment of osteoporosis in older women

    In those with 1 fragility fracture and/or +ve DEXA

    Bisphosphonate: Alendronate or Risedronate

    + Vitamin D and Calcium

    Not tolerated or contra-indicated

    Raloxifene (or Strontium ranelate)

    Further fractures or very severe osteoporosis

    Teriparatide

    NICE Technological Appraisal 87,

    www.nice.org.ukSIGN guideline 71, www.sign.ac.uk

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    Uncertainties

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    Falls prevention in hospitals and care homes

    Meta-analysis of the evidence for strategies to prevent falls or fractures in

    care home residents or hospital in-patients (Oliver et al BMJ 2007; 334:82)

    Care homes:

    Hip protectors reduced hip

    fractures by 0.67 (CI 0.46-0.98)but

    Hospitals:

    Multifaceted interventions reduced

    falls rate (0.82 (C.I. 0.68-0.997)

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    Other interventions investigated:

    Multifaceted interventions in care homes

    Single interventions:

    Physical restraint removal

    Fall alarm devices

    Exercise in care homes

    Calcium and vitamin D in care homes

    Changes in physical environment

    Medication review in hospitals

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    Hip protectors

    Cochrane review 2006

    Meta-analysis of 11 trials in care home settings:

    Reduction in incidence of hip fracture (RR 0.77 (95% C.I. 0.62-0.97)(but weak cluster randomisation methodology in 7 trials)

    Meta-analysis of 3 individually randomised trials in communitysettings: No reduction (RR 1.16 (95% C.I. 0.85-1.59)

    Poor acceptance (median 68%) and compliance rates (median 56%)

    Conclusion: hip protectors are ineffective for those living at home andtheir effectiveness in an institutional setting is uncertain.

    Parker et al. BMJ 2006

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    Falls prevention in dementia:

    Multifactorial intervention in patients with cognitiveimpairment

    RCT of those with MMSE of

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    From guidelines to service delivery

    England and Wales:Older Peoples NSF Standard on Falls 2001:

    NHS (with local councils) should take action to reduce falls andresultant injuries in their older populations

    All who have fallen should receive effective treatment andrehabilitation, and advice through a specialised falls service

    Response

    Falls registers for those at risk

    Falls specialist nurses

    Falls service coordinators Integrated Care Pathways

    Consultant-led falls clinics

    Exercise classes and safety advice

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    Scotland???

    Falls have not been a National Executive orhealth board priority

    Key challenges Scale of problem: at least 15% of those over 65 years? Delivery of annual check for falls

    Follow up of A&E attenders with falls

    Follow up of those helped up at home by emergencyservices

    Bolting on osteoporosis management

    Acceptability of programmes to older people

    Cost effectiveness?

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    Cit f Edi b h F ll d F t

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    City of Edinburgh Falls and Fracture

    Prevention Pathway

    WHO SHOULD BE REFERRED?

    All those with more than one fall in the past year

    All those who have presented to the medical serviceswith a fall

    All those who have had one fall in the past year and are

    unsteady on a Get up and Go test

    Those whose falls are possible blackouts

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    City of Edinburgh Falls and Fracture

    Prevention Pathway

    RAPID RESPONSE TEAMS

    Housebound

    2 falls in the past month

    Injury sustained due to fall

    DAY HOSPITAL

    (Liberton or Royal Victoria or Leith)

    Blackouts

    Unsteady with no obvious cause

    Postural hypotension that is difficult

    to control Patients who dont fulfill RRT criteria

    WHERE SHOULD THEY BE REFERRED?

    OPTHALMOLOGY: Cataracts

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    City of Edinburgh Falls and Fracture

    Prevention Pathway

    WHAT INTERVENTIONS TAKE PLACE?

    Full MDT assessment + Physio: strength and balance training

    OT: home hazard assessment and safety advice Integrated Care pharmacist team: medication review

    Osteoporosis risk assessment and referral for DEXA if needed

    Postural blood pressure check

    Referral back to GP where medication or blood pressureproblems are identified or ?reason for poor balance.

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    Fracture prevention =

    Falls prevention

    +

    Osteoporosis treatment

    Next challenge: a comprehensive integrated service for all

    with falls and fractures

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    Downloaded from: StudentConsult (on 10 September 2006 03:19 PM)

    2005 Elsevier

    Measurement of Bone Mineral Density:

    Dual energy X ray absorptiometry (DEXA)

    T score = no of SD by which patient differs from mean peak BMD for young normal subjects

    Z score = no of SD by which patient differs from BMD in subjects of the same age

    OSTEOPENIA: T-score -1 to -2.5

    OSTEOPOROSIS: T-score < -2.5

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    Non-pharmacological interventions

    High intensity strength training

    Low impact weight bearing exercise

    Dietary intake of calcium = 1000mg/day+ stop smoking

    moderate alcohol intake

    Scottish Intercollegiate Guidelines Network

    SIGN 71: Management of Osteoporosis

    www.sign.ac.uk

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    Vitamin D and Calcium

    Residents of care homes or specialist housing for theelderly

    Non-vertebral fracture reduced by 32%

    Hip fracture reduced by 43%

    Those with previous fragility fractures living in thecommunity

    No reduction in fractures

    ?beneficial effects on neuromuscular function associatedwith falls

    Chapuy MC et al. N Engl J Med1992

    Porthouse J et al. BMJ 2005

    Grant AM et al. Lancet 2005

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    Hip protectors

    Cochrane review 2006

    Meta-analysis of 11 trials in care home settings:

    Reduction in incidence of hip fracture (RR 0.77 (95% C.I. 0.62-0.97)

    Meta-analysis of 3 individually randomised trials in communitysettings: No reduction in hip fracture (RR 1.16 (95% C.I. 0.85-1.59)

    Poor acceptance (median 68%) and compliance rates (median 56%)

    Conclusion: hip protectors are ineffective for those living at home andtheir effectiveness in an institutional setting is uncertain.

    Parker et al. BMJ 2006

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    Falls and fracture prevention

    Balance and ageing

    Risk factors for falls

    Falls prevention: Evidence Falls prevention: Guidelines

    Applying the guidelines

    National developments

    Local services