Esco Service Guide...• North American facilities in Pennsylvania and Ohio Sales, service,...
Transcript of Esco Service Guide...• North American facilities in Pennsylvania and Ohio Sales, service,...
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Decontamination and Maintenance • Validation and Certification Parts Replacement • Aftermarket Support • Training and Workshops
Esco Service Guide
Esco Service Guide
Guide to Esco Products and Services
Table of Contents:
Corporate Profile ............................................................................ 3
Products and Application ................................................................ 4
Global Network .............................................................................. 4
Decontamination and Maintenance ................................................ 5
Parts Replacement .......................................................................... 5
Validation and Certification ............................................................ 5
Descriptions of Esco Validation and Certification Services ................ 6
IQ/OQ Documentation .................................................................... 6
Aftermarket Support ...................................................................... 7
Training and Workshop .................................................................. 7
Biological Safety Cabinets ............................................................... 8
Compounding Pharmacy Equipment .............................................. 9
Ductless Fume Hoods ................................................................... 10
Special Purpose Cabinets .............................................................. 11
Laboratory Fume Hoods ............................................................... 12
Lab Animal Research Products ...................................................... 13
Laminar Flow Clean Benches ........................................................ 14
Powder Weighing Balance Enclosures ........................................... 15
Esco Service Guide
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• A leader in the development of controlled environment,
laboratory and cleanroom equipment solutions.
• A world leader in biological safety cabinets.
• Headquartered in Singapore.
• North American facilities in Pennsylvania and Ohio
Sales, service, logistics for US & Canada.
• Other Esco locations in Bahrain, China, India, Malaysia,
Netherlands, UK.
• Group total of more than 500 employees.
• Distributors in more than 100 countries.
• Products independently tested to international standards.
• Large R&D investments, world leading technologies.
• State-of-the-art production, vertically integrated, 300,000
sq. ft. floor space.
• Worldwide service.
Welcome to Esco
Pictured: Esco Micro Pte. Ltd. is headquartered in Singapore, a modern city state located in Southeast Asia with a population of more than 4 million. From Singapore, Esco manages operations throughout the world.
Esco’s Vision is to provide enabling technologies for scientific discoveries to make human lives
healthier and safer.
Pictured: Esco provides service worldwide via a network of highly trained factory direct and independent service representatives."
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Esco Service Guide
Global Network
Products and Application
Esco Controlled Environment Equipment Solutions
Laboratory Equipment
Biosafety and Laminar Flow
•ClassIITypeA2BiologicalSafety
Cabinets
•ClassIITypeB2BiologicalSafety
Cabinets
•ClassIIIBiologicalSafetyCabinets
•HorizontalLaminarFlowCleanBenches
•InVitroFertilizationWorkstations
•LaboratoryAnimalResearchWorkstations
•PCRCabinets
•VerticalLaminarFlowCleanBenches
Fume Hoods
•DuctlessFumeHoods
•ExhaustBlowers
•FumeHoodAirflowMonitors
•FumeScrubbers
•LaboratoryFumeHoods
Incubators and Ovens
•CO2Incubators
•ForcedConvectionLaboratoryIncubators
•ForcedConvectionLaboratoryOvens
•LowTemperatureBODIncubators
•NaturalConvectionLaboratoryIncubators
•RemoteMonitoring,DataLogging,
andProgrammingSoftware
Life Science
•PCRThermalCyclers
Not Available in North America
Cold Chain Storage
•UltraLowTemperatureFreezers
Cleanroom Equipment•AirShowers
•GarmentStorageCabinets
•PassBoxes
•SoftCapsuleCleanrooms
•StraddleUnits
•TransferHatches
Pharmaceutical Equipment•CytotoxicSafetyCabinets
•DownflowBooths
•PharmacyIsolators
•PowderWeighingBalanceEnclosures
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Proper operation of Esco products usually requires periodic maintenance and/or decontamination in accordance with common Standard Operating Procedures and recognized laboratory safety protocols.
Decontamination is a process that reduces contaminants to acceptable levels in biological safety cabinets to eliminate their disease causing capabilities. Decontamination/fumigation using formaldehyde, hydrogen peroxide or other agents should only be carried out by trained personnel with proper knowledge and equipment.
Every Esco cabinet is manufactured as a commercial grade product and Esco provides replacements for consumable elements as well as any components that might fail while the product is in service.
Every Esco product is shipped with a Statement of Part Numbers for Replaceable Parts. From time to time, Esco may use components from different sources or change them after design improvements. The serial number of a product, usually located on an identification tag on its upper front side, may be used to query an on-line database to retrieve accurate part numbers.
In order to maintain consistent and safe operating conditions for any equipment, regular performance tests must be conducted. Esco’s Validation and Certification Services can ensure that all Esco equipment is providing sufficient containment in the equipment’s work areas and a pleasant working environment for its operators.
Qualified from the Start
Esco is committed to manufacture products compliant with international standards for performance, safety and energy efficiency for its worldwide market. We are equally committed to manufacturing processes, administrative documentation, and product certification testing compliant with applicable certifications, GLP (good laboratory practices) and cGMP (current good manufacturing practices). This is critical to our business model and to our relationships with customers, distributors and certifying agencies.
Support after the Sale
Esco’s customers subject its products to IQ/OQ validation or similar Standard Operating Procedures (SOPs), many of which Esco itself uses during the design and manufacture of its products. Some of the tests and procedures require calibrated equipment and certified operators. Although many customers perform these SOPs in house, others choose to outsource them to supplement their capabilities, control time lines, and obtain independent verification of results.
Esco provides its customers with IQ/OQ documentation for its products and offers a broad range of validation, certification and maintenance services to support their needs. Regular attention to equipment performance will ensure optimal performance and early detection and correction of potential problems, thus increasing utilization and product yields.
Validation and Certification Services Staff
Esco is a firm with trained field service engineers, specializing in the testing and certification of:
• BiologicalSafetyCabinets• AnimalContainmentWorkstations• HospitalPharmacyWorkstations• LaminarFlowCleanBenches• ApplicationSpecificCabinets• DuctlessFumeHoods• FumeHoods(Ducted)
Thoroughly trained, experienced and competent engineers perform clean room and associated clean air device certification in accordance with NEBB procedural standards, IEST (Institute of Environmental Sciences) Recommended Practices, ISO 14664.1, the NSF 49 Standard for Biosafety Cabinets, EN12469 European Norm Standard for Microbiological Safety Cabinets, and others. We also offer customized certification audits and evaluation programs for clean rooms and associated clean air devices.
Decontamination and Maintenance
Parts Replacement
Validation and Certification
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Esco Service Guide
Service Description
Airflow Balancing Adjust cabinet internal flow control devices to produce desired air flow.
ULPA / HEPA Filter Integrity Determine the integrity of down flow and exhaust filters by measuring penetration of a test aerosol.
ULPA / HEPA Filter Replacement Replace compromised filters or those at the end of their service life.
Inflow / Face Velocity Determine the velocity profile of air entering a cabinet through its work access opening via measurement and calculation.
Laminar Flow Velocity Determine the velocity profile of air moving within a cabinet work space using a thermal anemometer.
Particle Count Verify work zone air cleanliness in accordance with ISO 14644.1 classification criteria by particle counting.
Airflow Visualization Qualitatively evaluate airflow into work access area by visualizing smoke patterns.
Airflow Alarm Calibration Adjust the alarm set point of the airflow measurement system.
Blower / Fan Replacement Remove and replace a defective blower or fan assembly.
Electrical Troubleshooting Examine electrical devices, wiring connections and adjustments in a cabinet to diagnose and correct improper operation.
Electrical Safety Inspect grounding system and measure leakage currents in a cabinet electrical system to ensure equipment safety.
GFCI Performance Test Ground Fault Circuit Interrupter outlets, when installed, to ensure proper operation and protection.
Pressurization Measure pressure differentials from ambient in cabinet work space and/or pass-through to evaluate adequacy.
Enclosure Integrity Assess the integrity of the surfaces, seams and joint of a cabinet.
Product Ingress / Egress Measure particle counts during material transfer procedures into/out of glove boxes/isolators to verify acceptable values.
Recovery Time Measure the time interval after simulated major contamination for a cabinet work zone to return to acceptable cleanliness.
Glove Breach Verify the integrity of a glove and its attachment system to an isolator/glove box by measuring inward airflow at an open glove port.
Decontamination Biologically sterilize a cabinet using formalin vapor or hydrogen peroxide.
Noise Measure the corrected A-weighted sound level pressure produced by the fan(s).
Light Measure the lighting intensity at the work surface in a cabinet.
Vibration Measure vibration level of the work surface to prevent damage to sensitive processes and to ensure operator comfort.
UV Intensity Measure the effectiveness of the ultraviolet lamp, when installed, for surface germicidal decontamination.
Site Installation Assessment Verify proper installation of cabinet pursuant to recommended practices regarding location, external connections, etc.
KI Discus Containment Determine the containment integrity of a cabinet by measurement of potassium iodide droplet leakage.
SF6 Chemical Containment Determine the containment integrity of a cabinet by measurement of sulfur hexafluoride gas leakage.
Carbon Filter Retention Measure the adsorption capacity of a carbon filter to assess performance.
Carbon Filter Replacement Remove and replace compromised carbon filters or those at the end of their service life.
Aerosol Induction (Sash Seal) Inspect for leakage of the sash seal of a cabinet using an aerosol.
Temperature Calibration Sensor adjustment, temperature fluctuation, temperature uniformity and temperature recovery test.
CO2 Calibration Sensor adjustment, CO2 fluctuation and CO2 recovery test.
O2 Calibration Sensor adjustment, O2 fluctuation and O2 recovery test.
Humidity Calibration Sensor adjustment, humidity fluctuation and humidity recovery test.
Heater Replacement Remove and replace a defective heater assembly.
Pump Replacement Remove and replace a defective pump.
Piping Replacement Remove and replace compromised piping.
Compressor Replacement Remove and replace a defective compressor.
Thermostat Replacement Remove and replace the hard wired safety thermostat.
Pre-Filter Replacement Remove and replace compromised pre-filters filters or those at the end of their service life.
Lamp Replacement Remove and replace defective or underperforming cabinet fluorescent and/or ultraviolet lamp bulbs.
General Cleaning and Maintenance Thoroughly inspect, clean surfaces of, and make performance adjustments on a cabinet.
Esco and/or our officers are members of the following professional organizations:
• ControlledEnvironmentTestingAssociation(CETA)• ScientificEquipment&FurnitureAssociation(SEFA)• InstituteofEnvironmentalSciencesandTechnology(IEST)• LaboratoryProductsAssociation(LPA)• AmericanBiologicalSafetyAssociation(ABSA)• NSFInternational
We also offer these services through a network of certified subsidiary companies and international distributors and partners.
Descriptions of Esco Validation and Certification Services
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Esco offers in-warranty and post-warranty support for all products.
Extended Warranty
Extensions of Esco's standard warranty against defects in materials and workmanship are available. Extended warranties fix the capital cost of ownership of the product over its entire service life by eliminating the risk of failure due to latent defects.
Technical Support Subscription
Esco provides technical support via email and telephone, including troubleshooting performance issues, answering questions about product operation and maintenance, and assisting with certification.
Preventive Maintenance Agreements
Periodic preventive maintenance assures that Esco products provide desired performance. Preventive maintenance contracts are customer specified and may include periodic filter changing, decontamination, interior cleaning, and replacement of the UV lamp or other functions.
Replacement Manuals
All Esco products are shipped with comprehensive installation and operation documentation. While Esco Service Manuals include information for field-level maintenance, electrical component replacement and calibration.
Sentinel Software Upgrades
The Sentinel suite of microprocessor-based controllers operates on software developed for maximum performance and data management. New software releases are offered as required, and available for download via the Internet.
Esco offers training for users of its equipment on the procedures in its User and Service Manuals.
Operational training includes product placement, electrical connection, connection to facility air handling system, adjustment of leveling feet and locking of casters, use of Sentinel Software and pressure measurement instrumentation, cleaning, decontamination and changing filters.
Maintenance training includes the procedures used by our personnel and described above. You can assure that your personnel are prepared to deploy and use your Esco products.
Certification training is similar in scope to the training described above, and includes hands on demonstration of the skills being taught. The use of certified personnel facilitates assessing utilization, productivity and risks of complicated or sensitive protocols. Those who complete Esco Certification Workshops will receive a certificate of attendance.
Aftermarket Support
Training and Workshop
A certified process ensures that qualified equipment is used pursuant to validated Standard Operating Procedures (SOPs). Those SOPs that are applicable to equipment and instruments are classified as follows:
Installation Qualification (IQ) documents that the specified equipment was received and properly installed in a suitable environment. IQ is also required for used equipment installation, equipment moved within a facility or connected to modified systems at the facility or subject to a changed SOP. IQ can be performed by the customer or Esco.
Operational Qualification (OQ) documents that the equipment still meets its specifications after installation in the customer’s facility. OQ can be performed by the customer or Esco, and must be performed at least annually for every piece of equipment.
Esco provides our customers instructions for IQ and OQ of our products. Esco also can perform these services directly on behalf of its customers or arrange them through independent approved local certifiers. The availability may vary from country to country and region to region. Also, Esco can train customer employees to perform IQ/OQ as described in the Aftermarket Support section later in this document.
IQ/OQ Documentation
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Esco Service Guide
Esco Biological Safety Cabinets represent more than 20 locally, regionally and internationally-r e c o g n i z e d c e r t i f i c a t i o n s . These accreditations testify to the enhanced performance of Esco products in biological and microbiological applications.
Product lines:•Class II, Type A2 Biological Safety Cabinets.
•Class II, Type B2 Biological Safety Cabinets.
•Class III Biological Safety Cabinets.
• Formalin Vaporizers.
•Options and Accessories.
TheSafetySolutionforLifeScienceLaboratories
Biological Safety Cabinets
Pictured: Esco Biological Safety Cabinets
Testing/Maintenance ServiceBiological Safety Cabinets
Class I Cabinets Class II Cabinets Class III Cabinets
Airflow Balancing Standard Standard Standard
ULPA / HEPA Filter Integrity Standard Standard Standard
ULPA / HEPA Filter Replacement If Required If Required If Required
Inflow / Face Velocity Standard Standard
Laminar Flow Velocity Standard Standard
Particle Count Optional Optional
Airflow Visualization Standard Standard
Airflow Alarm Calibration If Required If Required If Required
Blower / Fan Replacement If Required If Required If Required
Electrical Troubleshooting If Required If Required If Required
Electrical Safety Optional Optional Optional
GFCI Performance Optional Optional Optional
Pressurization Standard
Enclosure Integrity Optional Optional Optional
Product Ingress / Egress Optional
Recovery Time Optional
Glove Breach Optional
Decontamination If Required If Required If Required
Noise Optional Optional Optional
Light Optional Optional Optional
Vibration Optional Optional Optional
UV Intensity Optional Optional Optional
Site Installation Assessment Optional Optional Optional
KI Discus Containment Optional Optional Optional
Aerosol Induction (Sash Seal) Optional Optional
Pre-Filter Replacement If Required If Required
Lamp Replacement If Required If Required If Required
General Cleaning and Maintenance If Required If Required If Required
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* Esco is a member of the NSF49 Joint Comittee that maintains the NSF49 standard* Esco participated in drafting the SFDA YY-0569 standard
Esco compounding pharmacy equipment includes a complete range of barrier isolators, NSF listed biological safety cabinets and clean benches.
Product lines:•Cytotoxic Safety Cabinets.
•Compounding Aseptic Isolators.
•Compounding Aseptic Containment Isolators
(Recirculating).
ThePremiumSolutionforSterileDrugCompounding
Compounding Pharmacy Equipment
Testing/Maintenance ServiceHospital Pharmacy Workstations
Hospital Pharmacy Isolators Cytotoxic Safety Cabinets
Airflow Balancing Standard Standard
ULPA / HEPA Filter Integrity Standard Standard
ULPA / HEPA Filter Replacement If Required If Required
Inflow / Face Velocity Standard
Laminar Flow Velocity Standard Standard
Particle Count Standard Standard
Airflow Visualization Standard
Airflow Alarm Calibration If Required If Required
Blower / Fan Replacement If Required If Required
Electrical Troubleshooting If Required If Required
Electrical Safety Optional Optional
GFCI Performance Optional Optional
Pressurization Standard
Enclosure Integrity Standard Optional
Product Ingress / Egress Optional
Recovery Time Optional
Glove Breach Optional
Decontamination If Required If Required
Noise Optional Optional
Light Optional Optional
Vibration Optional Optional
Site Installation Assessment Optional Optional
KI Discus Containment Optional
Aerosol Induction (Sash Seal) Optional
Pre-Filter Replacement If Required
Lamp Replacement If Required If Required
General Cleaning and Maintenance If Required If Required
Pictured: Esco Compounding Pharmacy Equipment
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Esco Service Guide
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Esco ductless and laboratory fume hoods serve to control exposure to toxic, offensive or flammable vapors, gases and aerosols.
Product lines:•General Purpose Benchtop Hoods.
•Acid Digestion Hoods.
• Perchloric Acid Hoods.
• Radioisotope Hoods.
• Floor Mounted Hoods.
•High Performance, Low Flow Hoods.
• Educational Hoods.
• Polypropylene Hoods.
•Chemical Fume Scrubbers.
• Exhaust Blowers.
• DuctlessFumeHoods.
LaminarTopographyandPerfectProtectionPerimeter
Fume Hoods
Testing/Maintenance Service D Ductless Fume Hoods Laboratory Fume Hoods
Inflow / Face Velocity Standard Standard
Airflow Visualization Standard Standard
Airflow Alarm Calibration If Required If Required
Blower / Fan Replacement If Required
Electrical Troubleshooting If Required If Required
Electrical Safety Optional Optional
GFCI Performance Optional Optional
Noise Optional Optional
Light Optional Optional
Vibration Optional Optional
Site Installation Assessment Optional
SF6 Chemical Containment Optional
Carbon Filter Retention Optional
Carbon Filter Replacement Optional
Pre-Filter Replacement If Required
Lamp Replacement If Required If Required
General Cleaning and Maintenance If Required If Required
Pictured: Esco Laboratory Fume Hoods
Testing/Maintenance ServiceSpecial Purpose Cabinets
IVF RHL PCR
Airflow Balancing Standard Standard Standard
ULPA / HEPA Filter Integrity Standard Standard Standard
ULPA / HEPA Filter Replacement If Required If Required If Required
Inflow / Face Velocity Standard
Laminar Flow Velocity Standard Standard
Particle Count Standard Standard
Airflow Visualization Optional Optional Optional
Airflow Alarm Calibration If Required If Required If Required
Blower / Fan Replacement If Required If Required If Required
Electrical Troubleshooting If Required If Required If Required
Electrical Safety Optional Optional Optional
GFCI Performance Optional Optional Optional
Noise Optional Optional Optional
Light Optional Optional Optional
Vibration Optional Optional Optional
UV Intensity Standard
Aerosol Induction (Sash Seal) Optional Optional
Pre-Filter Replacement If Required If Required If Required
Lamp Replacement If Required If Required If Required
General Cleaning and Maintenance If Required If Required If Required
Esco special purpose cabinets are designed for a specific applications that cannot be handled by any other equipment.
Product lines:• In Vitro Fertilization Workstations.
• Reverse Horizontal Laminar Flow Cabinets.
• PCRWorkstations.
EscoIn VitroFertilizationWorkstations
Special Purpose Cabinets
Pictured: Esco Special Purpose Cabinets
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Esco Service Guide
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Esco is the world leader in premium laminar flow cabinets for the global life sciences market.
Product lines:•Horizontal Laminar Flow Clean Benches.
•Vertical Laminar Flow Clean Benches.
TheLeadingSolutionforResearchLaboratories
Laminar Flow Clean Benches
Testing/Maintenance Service Laminar Flow
Airflow Balancing Standard
ULPA / HEPA Filter Integrity Standard
ULPA / HEPA Filter Replacement If Required
Inflow / Face Velocity Standard
Airflow Visualization Standard
Airflow Alarm Calibration If Required
Blower / Fan Replacement If Required
Electrical Troubleshooting If Required
Electrical Safety Optional
GFCI Performance Optional
Enclosure Integrity Optional
Recovery Time Optional
Decontamination If Required
Noise Optional
Light Optional
Vibration Optional
UV Intensity Optional
Site Installation Assessment Optional
Aerosol Induction (Sash Seal) Optional
Pre-Filter Replacement If Required
Lamp Replacement If Required
General Cleaning and Maintenance If Required
Pictured: Esco Laminar Flow Clean Benches
Testing/Maintenance Service Animal Containment Workstations
Airflow Balancing Standard
ULPA / HEPA Filter Integrity Standard
ULPA / HEPA Filter Replacement If Required
Inflow / Face Velocity Standard
Particle Count Optional
Airflow Visualization Optional
Airflow Alarm Calibration If Required
Blower / Fan Replacement If Required
Electrical Troubleshooting If Required
Electrical Safety Optional
GFCI Performance Optional
Decontamination If Required
Noise Optional
Light Optional
Vibration Optional
KI Discus Containment Optional
Carbon Filter Retention Optional
Carbon Filter Replacement Optional
Pre-Filter Replacement If Required
Lamp Replacement If Required
General Cleaning and Maintenance If Required
Animal research, cage changing and bedding disposal procedures are now simpler, safer and more productive with the Esco range of VIVA® Lab Animal Research Products.
Product lines:•Universal Access Animal Containment
Workstations.
•Dual Access Animal Containment
Workstations.
• Bedding Disposal Workstations.
EscoSolutionforAnimalResearchLaboratories
Lab Animal Research Products
Pictured: Esco Lab Animal Research Products
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Esco Service Guide
Laboratory operations involving weighing, mixing and dispensing hazardous or nuisance powders can now be performed safely and economically with the Esco Powdermax 1 Powder Weighing Balance Enclosure.
Product lines:• Powder Weighing Balance Enclosures.
Powder Weighing Balance Enclosures
Pictured: Esco PW1 Product
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Testing/Maintenance Service Powder Weighing Balance Enclosures
Airflow Balancing Standard
ULPA / HEPA Filter Integrity Standard
ULPA / HEPA Filter Replacement If Required
Inflow / Face Velocity Standard
Airflow Visualization Standard
Airflow Alarm Calibration If Required
Blower / Fan Replacement If Required
Electrical Troubleshooting If Required
Electrical Safety Optional
GFCI Performance Optional
Noise Optional
Light Optional
Vibration Optional
KI Discus Containment Optional
Pre-Filter Replacement If Required
Lamp Replacement If Required
General Cleaning and Maintenance If Required
Testing/Maintenance Service Oven IncubatorsCO2
IncubatorsFreezers
ULPA / HEPA Filter Replacement If Required
Blower / Fan Replacement If Required If Required* If Required If Required
Electrical Troubleshooting If Required If Required If Required If Required
Electrical Safety Optional Optional Optional Optional
Enclosure Integrity Standard Standard Standard Standard
Noise Optional
UV Intensity Optional** Optional
Temperature Calibration Standard Standard Standard Standard
CO2 Calibration Optional
O2 Calibration Optional
Humidity Calibration Optional
Heater Replacement If Required If Required If Required
Pump Replacement If Required
Piping Replacement If Required** If Required
Compressor Replacement If Required** If Required
Thermostat Replacement If Required If Required***
Lamp Replacement If Required** If Required
General Cleaning and Maintenance If Required If Required If Required If Required
Esco thermostatics products are able to provide precisely controlled environment for all your laboratory needs.
Product lines:•Ultra Low Temperature Freezers.
•CO2 Incubators.
• Forced Convection Laboratory Ovens.
• Forced Convection Laboratory Incubators.
•Natural Convection Laboratory Incubators.
• Low Temperature BOD Incubators.
EscoReliableSolutionforPCRProcess
Thermostatics Products
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Notes: * Not applicable to Natural Convection Laboratory Incubators (INA)** Only applicable to Low Temperature BOD Incubators (IFC)*** Only applicable to Forced Convection Laboratory Incubators (IFA)
Pictured: Esco Thermostatics Product
PT Esco Bintan IndonesiaCert. No: 651333/1
Esco Micro Pte Ltd Cert. No: 651333
LIVE SUPPORTescoglobal.com
LIVE SUPPORTescoglobal.com
EscoTechnologies,Inc.•2940TurnpikeDrive,Units15-16•Hatboro,PA19040,USAToll-FreeUSAandCanada877-479-3726•Tel215-441-9661•Fax215-441-9660us.escoglobal.com•[email protected]
EscoMicroPte.Ltd.•21ChangiSouthStreet1•Singapore486777Tel+6565420833•Fax+6565426920•[email protected]
Esco Global Offices | Beijing, China | Breukelen, The Netherlands | Guangzhou, China | Kuala Lumpur, MalaysiaManama, Bahrain | Marietta, OH, USA | Mumbai, India | Philadelphia, PA, USA | Salisbury, UK | Shanghai, China | Singapore
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