Macromolecules 4 major classes of macromolecules: carbohydrates lipids proteins nucleic acids.
Brief Overview of Macromolecules DNA, RNA, and Proteins.
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Transcript of Brief Overview of Macromolecules DNA, RNA, and Proteins.
Brief Overview of Macromolecules
DNA, RNA, and Proteins
What is “genomics”?
--The systematic study of the genome using large-scale DNA sequencing, gene-expression analysis, or computational methods.
Genome: the total complement of genes contained in a cell or virus, commonly used to refer to all genes present in one complete haploid set of chromosomes in eukaryotes.
Genome Sizes
•Saccharomyces cerevisiae 13 Mb
•Drosophila melanogaster 120 Mb
•Homo sapiens 3,200 Mb
•Fern 160,000 Mb
•Amoeba dubia 670,000 Mb
DNA Structure
Base / nucleotide pair: a pair of nitrogenous bases, most commonly one purine and one pyrimidine, held together by hydrogen bonds in a double stranded region of a nucleic acid molecule.
Purines vs. Pyrimidines
Nucleosides and Nucleotides
DNA = deoxyribonucleic acid
adenosineATP
Polynucleotide Chain
The Double Helix
RNA vs. DNA
RNA Structure
Single stranded
Summary of DNA vs. RNA
Protein Structure
Made up of amino acid chain.
Peptides