Amino Acids as Protein Building Blocks

Proteins are naturally-occurring biopolymers comprised of amino acids.

The biological function of proteins is inherent in their three dimensional structure.

All the information required for correct folding of the protein into its functional native structure is contained in the primary sequence of amino acids.

The physical chemical properties of the amino acids contain the biological information required for folding and function.

MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG

Structure of Ubiquitin

By convention the primary sequence of amino acids is listed left to right from the amino terminus to the carboxyl terminus.

Fundamental Structure of Amino Acids

Amino acids are most logically grouped according to the physical properties of their side chains.

Aliphatic Amino Acids

Aromatic Amino Acids

Polar Amino Acids

Disulfide Bond Formation

Acidic Amino Acids

Mechanism of Asn/Gln Deamidation

Basic Amino Acids

R74D39

R72K27E51D52E24R54

E18K63

Representations of Protein Surfaces

Amino Acids as Protein Building Blocks

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