CNS NOTES
Dementia
© 2009 NHS National Genetics Education and Development CentreGenetics and Genomics for Healthcare Huntington Disease An overview.
Ataxin-3 Expression and HSR
Dominant neurodegenerative disease Polyglutamine repeat expansions (CAG, codon, Q) in exon 1 of huntingtin gene (htt). Usually >35 CAG repeats.
Huntington Disease (HD) This presentation includes: Clinical classification and features. Structure and molecular basis of the HD gene. Clinical photographs.
OGMS Applied OGMS is the Ontology for General Medical Science, which provides definitions for all the terms (such as ‘disorder’, ‘symptom’, and so forth)
ZEESHAN GAUHAR PhD SCHOLOR-BIOTECHNOLOGY 14-ARID-4978.
Genetics and Populations Chapter 14. Central Points Genetic conditions can be very common in a specific community Huntington disease affects large.
EUKARYOTIC GENE EXPRESSION. DNA PACKING Histones Nucleosomes (1 st ) 30nm fibers (2 nd ) Looped domains (3 rd ) Heterochromatin – not transcribed, metaphase.
Huntington’s Disease
Genetics and Populations
