A B

C

Supplementary Figure 7

con E2-9 R5020-8 E2-9+R5020-8

0

50

100

150

200

250

300

350

400

450

DN

A c

onte

nt

(% o

f co

ntr

ol) **

*

**

con E2 MPA-8 MPA-7 MPA-6 MPA-8+E2

MPA-7+E2

MPA-6+E2

0

50

100

150

200

250

300

350

400

450

DN

A c

onte

nt

(% o

f c

ontr

ol)

*

****

****

con E2 Dex-8 Dex-7 Dex-6 DEX-8+E2

DEX-7+E2

DEX-6+E2

0

50

100

150

200

250

300

350

400

450

DN

A c

onte

nt

(% o

f c

ontr

ol) **

** ****

* **