Download - KIT

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Page 1: KIT

KIT

pKIT Y719

pKIT Y703

PI3K

AKT

pAKT S473

MAPK

pMAPK

Tubulin

A: UZLX-GIST3KIT exon 11

Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL

KIT

pKIT Y719

pKIT Y703

PI3K

AKT

pAKT S473

MAPK

pMAPK

Tubulin

B: UZLX-GIST4KIT exon 11

Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL

KIT

pKIT Y719

pKIT Y703

PI3K

AKT

pAKT S473

MAPK

pMAPK

Tubulin

C: UZLX-GIST2KIT exon 9

Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL Control IMA BKM IMA+BKM

KIT

pKIT Y719

pKIT Y703

PI3K

AKT

pAKT S473

MAPK

pMAPK

Tubulin

KIT

pKIT Y719

pKIT Y703

PI3K

AKT

pAKT S473

MAPK

pMAPK

Tubulin

D: GIST48KIT exon 11 + 17

Control IMA BKM IMA+BKM

Supplementary Figure 2_Van Looy et al.

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