KIT
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KIT pKIT Y719 pKIT Y703 PI3K AKT pAKT S473 MAPK pMAPK Tubulin A: UZLX-GIST3 KIT exon 11 Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL KIT pKIT Y719 pKIT Y703 PI3K AKT pAKT S473 MAPK pMAPK Tubulin B: UZLX-GIST4 KIT exon 11 Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL KIT pKIT Y719 pKIT Y703 PI3K AKT pAKT S473 MAPK pMAPK Tubulin C: UZLX-GIST2 KIT exon 9 Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL Control IMA BKM IMA+BKM KIT pKIT Y719 pKIT Y703 PI3K AKT pAKT S473 MAPK pMAPK Tubulin KIT pKIT Y719 pKIT Y703 PI3K AKT pAKT S473 MAPK pMAPK Tubulin D: GIST48 KIT exon 11 + 17 Control IMA BKM IMA+BKM Supplementary Figure 2_Van Looy et al.
description
Supplementary Figure 2_Van Looy et al. A: UZLX-GIST3 KIT exon 11. B: UZLX-GIST4 KIT exon 11. Control. IMA. BEZ. IMA+BEZ. Control. IMA. BYL. IMA+BYL. Control. IMA. BEZ. IMA+BEZ. Control. IMA. BYL. IMA+BYL. KIT. KIT. pKIT Y719. pKIT Y719. pKIT Y703. pKIT Y703. PI3K. - PowerPoint PPT Presentation
Transcript of KIT
KIT
pKIT Y719
pKIT Y703
PI3K
AKT
pAKT S473
MAPK
pMAPK
Tubulin
A: UZLX-GIST3KIT exon 11
Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL
KIT
pKIT Y719
pKIT Y703
PI3K
AKT
pAKT S473
MAPK
pMAPK
Tubulin
B: UZLX-GIST4KIT exon 11
Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL
KIT
pKIT Y719
pKIT Y703
PI3K
AKT
pAKT S473
MAPK
pMAPK
Tubulin
C: UZLX-GIST2KIT exon 9
Control IMA BEZ IMA+BEZ Control IMA BYL IMA+BYL Control IMA BKM IMA+BKM
KIT
pKIT Y719
pKIT Y703
PI3K
AKT
pAKT S473
MAPK
pMAPK
Tubulin
KIT
pKIT Y719
pKIT Y703
PI3K
AKT
pAKT S473
MAPK
pMAPK
Tubulin
D: GIST48KIT exon 11 + 17
Control IMA BKM IMA+BKM
Supplementary Figure 2_Van Looy et al.