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High Throughput Genotyping for Genomic Cohort Study
Woong-Yang Park
Department of Biochemistry and Human Genome Research Institute, Seoul National University College of Medicine
Human Genome Project (HGP) could unveil the secrets ofhuman being by a long script of genetic codes, whichenabled us to get access to mine the cause of diseasesmore efficiently. Two wheels for HGP, bioinformatics andhigh throughput technology are essential techniques for thegenomic medicine. While microarray platforms are stillevolving, we can screen more than 500,000 genotypes atonce. Even we can sequence the whole genome of anorganism within a day. Because the future medicne will
focus on the genetic susceptibility of individuals, we needto find genetic variations of each person by eff icientgenotyping methods.
J Prev Med Public Health 2007;40(2):102-107
Key words : Genotype, Sequence analys is, DNA,Microarray analysis, Single nucleot idepolymorphism
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Figure 3. Workflow of SNP genotyping using BeadArray.(cited from website of Illumina, http://www.illumina.com/)
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