Immune system Self/non-self recognition The state of protection
from infectious disease Memory Acceptance vs rejection Innate
immunityAdaptive immunity
Slide 4
Colonize the host Find a nutritionally compatible niche in the
hosts body Avoid, subvert, or circumvent the hosts innate and
adaptive immune responses Replicate, using host resources Exit and
spread to a new host Antigen (Ag) Establishment of infection
Ag Innate Adaptive ExtracellularPhagocytes B cells
Intracellular NK CD8 Tc cells (Altered self) Cytotoxicity CD4 Th
Humoral response Cell-mediated immunity (CMI) 1 2 Function of
immune cells Ag elimination is based on Ag location DC
Design of immune system Ag-specific recognition Pattern
recognition
Slide 29
Clonal selection Low frequency Immune diversity Adaptive
immunity Primary (Central) Secondary (Peripheral) B cell
development and humoral immunity Specificity