Cleanroom / BSC nozzle assembly

PLATFORMSPECIALIST.

1

• PrimaryHealthcareFacilities

• Pharmaceutical

Science Behined the Pocess

TheEscoBioVap™system is aprocessof atomizing thehydrogenperoxidesterilantcreatingadryfogasitisinjectedintothespace.Thisuniquesystem(patentpending)createsachargeontheatomizeddropletsasitpassesthroughthenozzle.Thischargeimpartedonthedropletsofsterilantcreatestwoimportantsynergies

a. Eachdropletofsterilantcontainsbillionsofreactive antimicrobialstoeffectmicrobialkill

b.Throughmutualrepulsionthechargeddropletsrepeleach otheranddistributethroughthespaceveryquicklyeffecting superiordistributionofthesterilant.Thechargeddroplets areattractedtotheunchargedsurfaceswithinthespace soonimpactthedropletsburstandimmediatelystartthe sterilisationprocess.

Duetotheseimportantfactorsthesterilantusedisminimizedandcanbeoflessconcentrationthanconventionalvaporizingsystemsthatneedtoevaporatethesterilantandthenwaitformicrocondensationtoeffectthesterilization.

This revolutionary bio-decontamination system is noteffectedbytemperatureorrelativehumiditythereforethereisno requirement toprecondition the spacebeing bio-decontaminatedandthereforeleadstoreducedcycle.

Introduction

EscoPharmahasdevelopedaneffectivehydrogenperoxidebasedbio-decontaminationsystemcapableofachievingalog6reductioninbio-burden.ThesporelogreductionhasbeenvalidatedbybiologicalindicatorchallengeusingbiologicalindicatorstainlesssteelribbonspopulatedwithGeobacillusStearothermophilusspores.

ThisBioVap™hasbeendevelopedinresponsetoincreasingdemandsfromthepharmaceutical, biotech,pharmacy,veterinaryandother related industries formicrobial freeenvironments and more stringent decontaminationrequirements.Hydrogenperoxidebreaksdownintooxygenandwater on completionof the sterilization processwhichmakesitoneofthemostenvironmentallyfriendlydecontaminant available. The BioVap™ is developed forperformingbio-decontaminationofasepticbarriersystem,passthroughsystems,biologicalsafetycabinets,cleanroomsandvirtuallyanyotherspacewheresurfacesterilizationofbio-decontaminationisrequired

Industries Served

• Hospital

• Food,Beverages&Confectionary

• ManufacturingFacilities

• VeterinarySurgeries

• Dentist

BioVapTM

Bio-decontamination System

SANITIZATION

Twolog-10-2

DISINFECTION

Fivelog-10-5

STERILIZATION

Sixlog-10-6

2

BioVapTM•BIO-DECONTAMINATION SYSTEM

2

Pre-Conditioning

Conventional Gaseous Systems

Gassing/Injection Dwell Aeration

Pre-Conditioning

BioVapTM System

Dwell Aeration

Time

Flexibility Features

EscoPharmaBioVapTMsystemisdevelopedtobeflexibleenoughtoworkinallareas,fromcabinetsandtransferhatchesuptomodularenclosurestoisolatorkeepinginmindthateverycustomerandfacilityhasdifferentrequirements.

Image of the cleanroom / BSCnozzle assembly

Image of fixed nozzle in isolator

EscoPharmaTransferHatchandBioVapTMintegratedsystem

EscoPharmaBioVapTM

systemasapremiumsolutionfordecontaminationprocessforallsizesofbiosafetycabinets.

EscoPharmaBioVapTM

systemintegratedintotheisolatorasourapproachtoacosteffectivebio-decontamination.

EscoPharmaBioVapTMfoggingsystemasaneffectivebio-decontaminationforcleanroomandorlaboratory.

PLATFORMSPECIALIST.

BioVapTMHMIController

Process Step

TheBioVap™bio-decontaminationcyclewillhavethefollowingphases

a. InjectionPhase–Inthisphasethesterilantwillbeinjectedintothespaceasadryfogatasetpressureandsetflowrateforaset

periodoftime,duringthisperiodtheatomizingpressure,theinjectionairflowandinjectionairpressurearemonitored.

b.DwellPhase-Inthisphasethesterilantisallowedtosettleonthesurfacesinsidethespaceforasetperiodoftime andeffectthemicrobialkill.

c. AerationPhase-Inthisphasethehydrogenperoxidesterilantisremovedfromthespace/enclosure.

Controls

TheBioVap™systemisPLCcontrolledwithoperatorinterfaceviaatouchscreenHMIterminalgivingoperatorlogonsecurityandrealtimedisplayofcycleparameters.Cycleparametersarealsorecordedandaprintoutofthecycleparametersisgivenattheendofacycleforvalidationrecords.Electronicdatarecordingofthecycles21CFR11compliantisavailableonrequest.20pre-programmedcyclescanbesavedonthePLCsystemselectablefromtheinterfaceterminal.TheBioVap™canbecontrolledlocallyviatheHMIlocatedontheBioVap™generatororcanbecontrolledremotelyfromanIsolatororcabinetcontrolsystem.

INNOVATIVE DESIGNGENERAL SPECIFICATIONS

Power Supply 240/110V,50/60Hzsinglephase

Air Supply 6barpressure200l/minflow(clean&dryair)

Sterilant 12%volhydrogenperoxide(100-400ul/minflow)

PLC SiemensS7-1200series

HMI SiemensTP170komfort

Printer Gebeticketlabelprinter

Spore Log Reduction UptoLog6

ORDERING INFORMATION

Option 1Isolator integration kit without PLC.

UtilizesIsolatorPLCtocontrol,monitorandreportonbio-decontamination.

Option 2Isolator information kit with PLC.

SystemcompletewithPLC,HMI&ticketprintermountedon304STSTenclosure

Option 3Mobile BioVapTM complete with PLC, HMI and printer.

Allhousedinwithinsturdymobilecase.Availablewithchoiceofnozzleassembly.

Nozzle Assembly A CleanroomNozzleAssembly

Nozzle Assembly B RemoteControlAssembly

CatalyticConverter

Adjustabletripodforbio-decontaminationofcleanroomandBSC

MobileBioVapTMSystemisfittedinsideahandycase

LIVE SUPPORTescoglobal.com

Since 1978, Esco has emerged as a leader in the development of controlled environment, laboratory and pharmaceutical equipment solutions. Products sold in more than 100 countries include biological safety cabinets, compounding pharmacy equipment, containment / pharma products, ductless fume hoods, in vitro fertilization workstations, lab animal research products, laboratory fume hoods, laboratory ovens and incubators, laminar flow clean benches and PCR products and instrumentation. With the most extensive product line in the industry, Esco has passed more tests, in more languages, for more certifications, throughout more countries than any biosafety cabinet manufacturer in the world. Esco remains dedicated to delivering innovative solutions for the clinical, life science, research and industrial laboratory community. www.escoglobal.com.

PT Esco Bintan IndonesiaCert. No: 651333/E

Esco Micro Pte Ltd Cert. No: 651076

PT Esco Bintan IndonesiaCert. No: Q2N130383797001

Biological Safety ProductsContainment / Pharma ProductsDuctless Fume Hoods / Carbon FiltrationGeneral Purpose Scientific EquipmentIndustrial Lab EquipmentIn-Vitro Fertilization ProductsPCR ProductsPharmacy ProductsLab Animal Research ProductsLab Thermostatics ProductsLab Ventilation / Chemical Fume Products / Lab FurniturePowder Handling Products

Airflow Alarms and Monitors • Biological Safety Cabinets • Exhaust Blowers Benchtop Laboratory Fume Hoods • High Performance Low Flow Fume Hoods

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Esco Technologies, Inc. • 903 Sheehy Drive, Suite F, Horsham, PA 19044, USAToll-Free USA and Canada 1-877-479-3726 • Tel 215-441-9661 • Fax 484-698-7757www.escolifesciences.us • eti.sales@escoglobal.com

Esco Micro Pte. Ltd. • 21 Changi South Street 1 • Singapore 486 777Tel +65 6542 0833 • Fax +65 6542 6920 • mail@escoglobal.comwww.escoglobal.com

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