Bio-decontamination System
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Cleanroom / BSC nozzle assembly PLATFORM SPECIALIST. 1 • Primary Healthcare Facilities • Pharmaceutical Science Behined the Pocess The Esco BioVap™ system is a process of atomizing the hydrogen peroxide sterilant creating a dry fog as it is injected into the space. This unique system (patent pending) creates a charge on the atomized droplets as it passes through the nozzle. This charge imparted on the droplets of sterilant creates two important synergies a. Each droplet of sterilant contains billions of reactive antimicrobials to effect microbial kill b. Through mutual repulsion the charged droplets repel each other and distribute through the space very quickly effecting superior distribution of the sterilant. The charged droplets are attracted to the uncharged surfaces within the space so on impact the droplets burst and immediately start the sterilisation process. Due to these important factors the sterilant used is minimized and can be of less concentration than conventional vaporizing systems that need to evaporate the sterilant and then wait for micro condensation to effect the sterilization. This revolutionary bio-decontamination system is not effected by temperature or relative humidity therefore there is no requirement to precondition the space being bio- decontaminated and therefore leads to reduced cycle. Introduction Esco Pharma has developed an effective hydrogen peroxide based bio-decontamination system capable of achieving a log 6 reduction in bio-burden. The spore log reduction has been validated by biological indicator challenge using biological indicator stainless steel ribbons populated with Geobacillus Stearothermophilus spores. This BioVap™ has been developed in response to increasing demands from the pharmaceutical, biotech, pharmacy, veterinary and other related industries for microbial free environments and more stringent decontamination requirements. Hydrogen peroxide breaks down into oxygen and water on completion of the sterilization process which makes it one of the most environmentally friendly decontaminant available. The BioVap™ is developed for performing bio-decontamination of aseptic barrier system, pass through systems, biological safety cabinets, cleanrooms and virtually any other space where surface sterilization of bio- decontamination is required Industries Served • Hospital • Food, Beverages & Confectionary • Manufacturing Facilities • Veterinary Surgeries • Dentist BioVap TM Bio-decontamination System SANITIZATION Two log-10 -2 DISINFECTION Five log-10 -5 STERILIZATION Six log-10 -6
Transcript of Bio-decontamination System
Cleanroom / BSC nozzle assembly
PLATFORMSPECIALIST.
1
• PrimaryHealthcareFacilities
• Pharmaceutical
Science Behined the Pocess
TheEscoBioVap™system is aprocessof atomizing thehydrogenperoxidesterilantcreatingadryfogasitisinjectedintothespace.Thisuniquesystem(patentpending)createsachargeontheatomizeddropletsasitpassesthroughthenozzle.Thischargeimpartedonthedropletsofsterilantcreatestwoimportantsynergies
a. Eachdropletofsterilantcontainsbillionsofreactive antimicrobialstoeffectmicrobialkill
b.Throughmutualrepulsionthechargeddropletsrepeleach otheranddistributethroughthespaceveryquicklyeffecting superiordistributionofthesterilant.Thechargeddroplets areattractedtotheunchargedsurfaceswithinthespace soonimpactthedropletsburstandimmediatelystartthe sterilisationprocess.
Duetotheseimportantfactorsthesterilantusedisminimizedandcanbeoflessconcentrationthanconventionalvaporizingsystemsthatneedtoevaporatethesterilantandthenwaitformicrocondensationtoeffectthesterilization.
This revolutionary bio-decontamination system is noteffectedbytemperatureorrelativehumiditythereforethereisno requirement toprecondition the spacebeing bio-decontaminatedandthereforeleadstoreducedcycle.
Introduction
EscoPharmahasdevelopedaneffectivehydrogenperoxidebasedbio-decontaminationsystemcapableofachievingalog6reductioninbio-burden.ThesporelogreductionhasbeenvalidatedbybiologicalindicatorchallengeusingbiologicalindicatorstainlesssteelribbonspopulatedwithGeobacillusStearothermophilusspores.
ThisBioVap™hasbeendevelopedinresponsetoincreasingdemandsfromthepharmaceutical, biotech,pharmacy,veterinaryandother related industries formicrobial freeenvironments and more stringent decontaminationrequirements.Hydrogenperoxidebreaksdownintooxygenandwater on completionof the sterilization processwhichmakesitoneofthemostenvironmentallyfriendlydecontaminant available. The BioVap™ is developed forperformingbio-decontaminationofasepticbarriersystem,passthroughsystems,biologicalsafetycabinets,cleanroomsandvirtuallyanyotherspacewheresurfacesterilizationofbio-decontaminationisrequired
Industries Served
• Hospital
• Food,Beverages&Confectionary
• ManufacturingFacilities
• VeterinarySurgeries
• Dentist
BioVapTM
Bio-decontamination System
SANITIZATION
Twolog-10-2
DISINFECTION
Fivelog-10-5
STERILIZATION
Sixlog-10-6
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BioVapTM•BIO-DECONTAMINATION SYSTEM
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Pre-Conditioning
Conventional Gaseous Systems
Gassing/Injection Dwell Aeration
Pre-Conditioning
BioVapTM System
Dwell Aeration
Time
Flexibility Features
EscoPharmaBioVapTMsystemisdevelopedtobeflexibleenoughtoworkinallareas,fromcabinetsandtransferhatchesuptomodularenclosurestoisolatorkeepinginmindthateverycustomerandfacilityhasdifferentrequirements.
Image of the cleanroom / BSCnozzle assembly
Image of fixed nozzle in isolator
EscoPharmaTransferHatchandBioVapTMintegratedsystem
EscoPharmaBioVapTM
systemasapremiumsolutionfordecontaminationprocessforallsizesofbiosafetycabinets.
EscoPharmaBioVapTM
systemintegratedintotheisolatorasourapproachtoacosteffectivebio-decontamination.
EscoPharmaBioVapTMfoggingsystemasaneffectivebio-decontaminationforcleanroomandorlaboratory.
PLATFORMSPECIALIST.
BioVapTMHMIController
Process Step
TheBioVap™bio-decontaminationcyclewillhavethefollowingphases
a. InjectionPhase–Inthisphasethesterilantwillbeinjectedintothespaceasadryfogatasetpressureandsetflowrateforaset
periodoftime,duringthisperiodtheatomizingpressure,theinjectionairflowandinjectionairpressurearemonitored.
b.DwellPhase-Inthisphasethesterilantisallowedtosettleonthesurfacesinsidethespaceforasetperiodoftime andeffectthemicrobialkill.
c. AerationPhase-Inthisphasethehydrogenperoxidesterilantisremovedfromthespace/enclosure.
Controls
TheBioVap™systemisPLCcontrolledwithoperatorinterfaceviaatouchscreenHMIterminalgivingoperatorlogonsecurityandrealtimedisplayofcycleparameters.Cycleparametersarealsorecordedandaprintoutofthecycleparametersisgivenattheendofacycleforvalidationrecords.Electronicdatarecordingofthecycles21CFR11compliantisavailableonrequest.20pre-programmedcyclescanbesavedonthePLCsystemselectablefromtheinterfaceterminal.TheBioVap™canbecontrolledlocallyviatheHMIlocatedontheBioVap™generatororcanbecontrolledremotelyfromanIsolatororcabinetcontrolsystem.
INNOVATIVE DESIGNGENERAL SPECIFICATIONS
Power Supply 240/110V,50/60Hzsinglephase
Air Supply 6barpressure200l/minflow(clean&dryair)
Sterilant 12%volhydrogenperoxide(100-400ul/minflow)
PLC SiemensS7-1200series
HMI SiemensTP170komfort
Printer Gebeticketlabelprinter
Spore Log Reduction UptoLog6
ORDERING INFORMATION
Option 1Isolator integration kit without PLC.
UtilizesIsolatorPLCtocontrol,monitorandreportonbio-decontamination.
Option 2Isolator information kit with PLC.
SystemcompletewithPLC,HMI&ticketprintermountedon304STSTenclosure
Option 3Mobile BioVapTM complete with PLC, HMI and printer.
Allhousedinwithinsturdymobilecase.Availablewithchoiceofnozzleassembly.
Nozzle Assembly A CleanroomNozzleAssembly
Nozzle Assembly B RemoteControlAssembly
CatalyticConverter
Adjustabletripodforbio-decontaminationofcleanroomandBSC
MobileBioVapTMSystemisfittedinsideahandycase
LIVE SUPPORTescoglobal.com
Since 1978, Esco has emerged as a leader in the development of controlled environment, laboratory and pharmaceutical equipment solutions. Products sold in more than 100 countries include biological safety cabinets, compounding pharmacy equipment, containment / pharma products, ductless fume hoods, in vitro fertilization workstations, lab animal research products, laboratory fume hoods, laboratory ovens and incubators, laminar flow clean benches and PCR products and instrumentation. With the most extensive product line in the industry, Esco has passed more tests, in more languages, for more certifications, throughout more countries than any biosafety cabinet manufacturer in the world. Esco remains dedicated to delivering innovative solutions for the clinical, life science, research and industrial laboratory community. www.escoglobal.com.
PT Esco Bintan IndonesiaCert. No: 651333/E
Esco Micro Pte Ltd Cert. No: 651076
PT Esco Bintan IndonesiaCert. No: Q2N130383797001
Biological Safety ProductsContainment / Pharma ProductsDuctless Fume Hoods / Carbon FiltrationGeneral Purpose Scientific EquipmentIndustrial Lab EquipmentIn-Vitro Fertilization ProductsPCR ProductsPharmacy ProductsLab Animal Research ProductsLab Thermostatics ProductsLab Ventilation / Chemical Fume Products / Lab FurniturePowder Handling Products
Airflow Alarms and Monitors • Biological Safety Cabinets • Exhaust Blowers Benchtop Laboratory Fume Hoods • High Performance Low Flow Fume Hoods
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Esco Technologies, Inc. • 903 Sheehy Drive, Suite F, Horsham, PA 19044, USAToll-Free USA and Canada 1-877-479-3726 • Tel 215-441-9661 • Fax 484-698-7757www.escolifesciences.us • [email protected]
Esco Micro Pte. Ltd. • 21 Changi South Street 1 • Singapore 486 777Tel +65 6542 0833 • Fax +65 6542 6920 • [email protected]
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