You have MS - ste · PDF file• Slurred speech • Tremors ... “I believe we are...
1
Searching for a CURE... STEM NEUROLOGICAL DISEASE RESEARCH There is no known cause for the disease. It can happen to you . . . or someone you love. Tragically, one in twenty people are touched by MS in their lifetime. You have MS Words no one wants to hear the average age for MS diagnosis 34 yrs • Blurred vision • Loss of balance • Poor coordination • Slurred speech • Tremors • Numbness • Extreme fatigue • Problems with memory and concentration • Paralysis • Blindness • Death The fear of a Neurological Disease is stronger than the fear of cancer This is why... MS has a HIGHER RATES of DEPRESSION than cancer, substance withdrawals, and epilepsy combined. What is Multiple Sclerosis? Multiple Sclerosis (MS) is a chronic unpredictable central nervous disorder that affects the brain and spinal cord. It is an autoimmune disease, which means the immune system mistakenly attacks normal, healthy parts of the body as if they were foreign and dangerous. MS causes the body to attack the thin protective nerve coverings, called Myelin, which slows the relay of instructions from the brain to the body, making motor functions difficult. MS is usually discovered between the ages of 20 and 40, and cannot be inherited. Because of complications related to the disease, the life expectancy of someone with MS is about 7 years less than someone without it. There is no cure . . . There is no cure . . . but there is hope MS research at Hadassah This is the story of one man’s mission to find a successful treatment for MS. The Story of MS research at Hadassah Hospital is amazing. At its heart is its mission to alleviate suffering and save lives. This is the story of a Greek-born scientist, and internationally acclaimed neuroimmunologist, Professor Dimitrios Karussis, who, together with his wife, left Greece and came to work at Hadassah. They and their family are now Israeli citizens. The work of Professor Karussis and his colleagues is causing the medical world to take notice. Three major U.S. medical research centres, including the Mayo Clinic, are now running studies using an identical protocol to the trials performed by Prof Karussis at Hadassah Hospital. The astonishing results have been appearing in reports of clinical trials using stem cells in patients suffering from Neurological diseases especially Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS). So, how close is Professor Karussis and his team to providing a revolutionary treatment that not only stops the progression of these until-now incurable neurological diseases, but reverses some of the damage and debilitation already caused? The trial, under the direction of Professor Karussis, has 48 patients in a double blind, placebo-controlled study. The novel concept of injecting stem cells directly into the spinal fluid is aimed at getting the cells to circulate to the various damaged areas of the central nervous system. “I believe we are in the early stages of something new and revolutionary with this harvested stem cell infusion therapy. I am confident that within the next three to five years, we may provide a treatment to patients that can stop the progression of these diseases and induce some kind of recovery. Preliminary results of our trial have seen wheelchair- bound patients getting back on their own two feet.” Prof Dimitrios Karussis Head, Multiple Sclerosis Center, Department of Neurology, Hadassah Hospital The research – a world first “Preliminary results have seen wheelchair-bound patients getting back on their own two feet” The results so far In the latest study reported at the end of 2016, 87% of patients responded positively to their treatment, with no serious side effects. • Disability was stabilised during the first 6 months following the treatment • Results indicated a halt of the progression of this disease. • Disability showed a clear trend for improvement, including substantial increases in motor function Mark is one of the UK’s most successful media lawyers. He was instrumental in bringing the case against News of the World, as a result of the 2011 phone hacking scandal. Mark was diagnosed with MS when he was 24. By 2016 he was using a wheelchair and mobility scooter and had given up driving. “I wish I could say to you I never feel sorry for myself but I always feel sorry for myself - I have moments of absolute depression,” he says. “My health had gone rapidly into a downward spiral. I heard about the medical trial in Hadassah. As a lawyer, all my working life I’d done trials, often very high profile, with a philosophy that every case at trial is 50/50. Either you win or you lose. “This was my most important trial. It was not just about cosmetic appearance but whether I would be able to work. My memory is unaffected, but my body was failing. “The research at Hadassah is miraculous. I joke that if there is a place where a miracle could happen, then Jerusalem is a suitable candidate. “Within two hours of my treatment, I could walk again without a stick and the pain that showed the onset of MS when I was 28 disappeared, 28 years, more than half my life, and it just disappeared within two hours of the transfusion. “I honestly feel that the treatment is not just life changing, but as my wife Mandy says “life giving”. It is a new lease of life.” Please see an interview by the BBC in November 2017. Mark Lewis’ story “I honestly feel that the treatment is not just life changing, it’s life giving.” Malia Litman’s story “They were creating miracles before I knew I needed one!” In 1999, I was too young, too busy, and I felt too good to have Multiple Sclerosis. I had been a nurse, so I knew that people with MS are in wheelchairs. But I did have Multiple Sclerosis. There was no explanation. There was no cure. As time passed my symptoms got worse. The turning point came because of a fall in gravel at my daughter’s school. I had fallen before, but this fall was not only the result of balance issues, but sheer weakness and fatigue. In 2013 I fell in the middle of the night and broke my leg. We installed handicapped railings in the bathroom. Muscles that I had previously used for walking had atrophied. I knew it was time to get more aggressive with my MS treatment. I researched the internet. Of all the physicians in the world, Prof Karussis’ Stem Cell research at Hadassah Hospital in Jerusalem seemed the most promising. His scientific method was sound. His results were exciting, and verifiable. Side effects seemed unlikely since he used the patient’s own stem cells taken through bone marrow extraction. After my first stem cell infusion, I realised immediate benefits. In less than 24 hours my speech improved. I had enhanced strength in my weakest leg, and improvement infine motor skills. The greatest change was a profound difference in fatigue. I may never walk without assistance, but I am a realist who believes in miracles. Hadassah Hospital and Prof Karussis have made my dreams become a reality. I will forever be indebted to them for giving me the miracle of hope. WE NEED YOUR HELP! Time is precious … You can give the gift of HOPE THE URGENT NEED A Transformational Philanthropic Campaign STEM Neurological Disease is one of the most INNOVATIVE and EXCITING research programs ever launched in this area. It has the real potential to RAPIDLY CHANGE the course of NEUROLOGICAL DISEASE RESEARCH and TREATMENT in Israel and worldwide. Ultimately STEM Neurological Disease will move us closer to one day halting the progression of neurological diseases that today are incurable. We need your help to end the needless suffering of people with neurological diseases around the world. We need your help Hadassah Australia must raise US$500,000 towards the $1.5m Prof Karussis still needs to complete the third MS trial and publish his ground breaking results When YOU donate to Hadassah, it has a powerful effect: “Restricting Medical Research due to funding has very real human consequences, measured in loss of life and tremendous suffering for patients and their families.” – Michael J Fox • YOU make broken lives whole and keep crucial medical research moving forward • YOU align yourself with a remarkable cause • YOU give a transformational gift Please give a gift that makes you PROUD All donations above $2 are tax deductible YOU can give hope to millions of people worldwide RANGE OF GIFTS 50,000.00 40,000.00 25,000.00 20,000.00 15,000.00 10,000.00 5,000.00 3,000.00 1,800.00 1,000.00 TOTAL NUMBER OF GIFTS 1 1 2 3 5 8 10 12 12 50 $500,000 (125 Gifts) How you can help us reach our target RESEARCH Hadassah Australia Head Office L1, 306 Hawthorn Road, Caulfield South VIC 3162 Hadassah Australia NSW Office Suite 602, 180 Ocean Street, Edgecliff NSW 2027 T: 1800 HADASSAH (1800 423 277) E: [email protected] www.stemneurologicaldisease.org
Transcript of You have MS - ste · PDF file• Slurred speech • Tremors ... “I believe we are...
Searching for a CURE...
STEM NEUROLOGICAL
DISEASE
RESEARCH
There is no known cause for the disease.
It can happen to you
. . . or someone you love.
Tragically, one in twenty people are touched by MS in their lifetime.
You have MSWords no one wants to hear
the average age for MS diagnosis
34yrs
• Blurred vision
• Loss of balance
• Poor coordination
• Slurred speech
• Tremors
• Numbness
• Extreme fatigue
• Problems with memory and concentration
• Paralysis
• Blindness
• Death
The fear of a Neurological Disease is stronger than the fear of cancer
This is why...
MS has a HIGHER RATES of DEPRESSION than cancer,
substance withdrawals, and epilepsy
combined.
What is Multiple Sclerosis?Multiple Sclerosis (MS) is a chronic unpredictable central nervous
disorder that aects the brain and spinal cord. It is an autoimmune
disease, which means the immune system mistakenly attacks
normal, healthy parts of the body as if they were foreign and
dangerous.
MS causes the body to attack the thin protective nerve coverings,
called Myelin, which slows the relay of instructions from the brain
to the body, making motor functions di�cult.
MS is usually discovered between the ages of 20 and 40, and
cannot be inherited. Because of complications related to the
disease, the life expectancy of someone with MS is about
7 years less than someone without it.
There is no cure . . .
There is no cure
. . . but there is
hope
MS research at Hadassah
This is the story of one man’s
mission to find a successful treatment
for MS.
The Story of MS research at Hadassah Hospital is amazing.
At its heart is its mission to alleviate su�ering and
save lives.
This is the story of a Greek-born scientist, and internationally acclaimed neuroimmunologist, Professor Dimitrios Karussis, who, together with his wife, left Greece and came to work at Hadassah.
They and their family are now Israeli citizens.
The work of Professor Karussis and his colleagues is causing the medical world to take notice.
Three major U.S. medical research centres, including the Mayo Clinic, are now running studies using an identical protocol to the trials performed by Prof Karussis at Hadassah Hospital.
The astonishing results have been appearing in reports of clinical trials using stem cells in patients suering from Neurological diseases especially Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS).
So, how close is Professor Karussis and his team to providing a revolutionary treatment that not only stops the progression of these until-now incurable neurological diseases, but reverses some of the damage and debilitation already caused?
The trial, under the direction of Professor Karussis, has 48 patients in a double blind, placebo-controlled study. The novel concept of injecting stem cells directly into the
spinal fluid is aimed at getting the cells to circulate to the various damaged areas of the central nervous system.
“I believe we are in the early stages of something new and revolutionary with this harvested stem cell infusion therapy.
I am confident that within the next three to five years, we may provide a treatment to patients that can stop the progression
of these diseases and induce some kind of recovery. Preliminary results of our trial have seen wheelchair-
bound patients getting back on their own two feet.”
Prof Dimitrios Karussis Head, Multiple Sclerosis Center,
Department of Neurology, Hadassah Hospital
The research – a world first
“Preliminary results have seen
wheelchair-boundpatients getting back
on theirown two feet”
The results so farIn the latest study reported at the end of 2016, 87% of patients responded positively to their treatment, with no serious side e�ects.
• Disability was stabilised during the first 6 months following the treatment
• Results indicated a halt of the progression of this disease.
• Disability showed a clear trend for improvement, including substantial increases in motor function
Mark is one of the UK’s most successful media lawyers. He was instrumental in bringing the case against News of the World, as a result of the 2011 phone hacking scandal.
Mark was diagnosed with MS when he was 24. By 2016 he was using a wheelchair and mobility scooter and had given up driving.
“I wish I could say to you I never feel sorry for myself but I always feel sorry for myself - I have moments of absolute depression,” he says.
“My health had gone rapidly into a downward spiral. I heard about the medical trial in Hadassah. As a lawyer, all my working life I’d done trials, often very high profile, with a philosophy that every case at trial is 50/50. Either you win or you lose.
“This was my most important trial. It was not just about cosmetic appearance but whether I would be able to work. My memory is unaected, but my body was failing.
“The research at Hadassah is miraculous. I joke that if there is a place where a miracle could happen, then Jerusalem is a suitable candidate.
“Within two hours of my treatment, I could walk again without a stick and the pain that showed the onset of MS when I was 28 disappeared, 28 years, more than half my life, and it just disappeared within two hours of the transfusion.
“I honestly feel that the treatment is not just life changing, but as my wife Mandy says “life giving”. It is a new lease of life.”
Please see an interview by the BBC in November 2017.
Mark Lewis’ story
“I honestly feel that the treatment is not just life changing, it’s life giving.”
Malia Litman’s story
“They were creating miracles before I knew I needed one!”
In 1999, I was too young, too busy, and I felt too good to have Multiple Sclerosis. I had been a nurse, so I knew that people with MS are in wheelchairs. But I did have Multiple Sclerosis.
There was no explanation. There was no cure.
As time passed my symptoms got worse.
The turning point came because of a fall in gravel at my daughter’s school. I had fallen before, but this fall was not only the result of balance issues, but sheer weakness and fatigue.
In 2013 I fell in the middle of the night and broke my leg. We installed handicapped railings in the bathroom. Muscles that I had previously used for walking had atrophied. I knew it was time to get more aggressive with my MS treatment.
I researched the internet. Of all the physicians in the world, Prof Karussis’ Stem Cell research
at Hadassah Hospital in Jerusalem seemed the most promising. His scientific method was sound. His results were exciting, and verifiable.
Side eects seemed unlikely since he used the patient’s own stem cells taken through bone marrow extraction.
After my first stem cell infusion, I realised immediate benefits. In less than 24 hours my speech improved. I had enhanced strength in my weakest leg, and improvement infine motor skills. The greatest change was a profound dierence in fatigue.
I may never walk without assistance, but I am a realist who believes in miracles.
Hadassah Hospital and Prof Karussis have made my dreams become a reality.
I will forever be indebted to them for giving me the miracle of hope.
WE NEED YOUR HELP!
Time is precious …
You can give the
gift of HOPE
THE URGENT NEED A Transformational Philanthropic Campaign STEM Neurological Disease is one of the most INNOVATIVE and EXCITING research programs ever launched in this area. It has the real potential to RAPIDLY CHANGE the course of NEUROLOGICAL DISEASE RESEARCH and TREATMENT in Israel and worldwide.
Ultimately STEM Neurological Disease will move us closer to one day halting the progression of neurological diseases that today are incurable. We need your help to end the needless su�ering of people with neurological diseases around the world.
We need your help
Hadassah Australia must raise US$500,000 towards the $1.5m Prof Karussis still needs to complete the
third MS trial and publish his ground breaking results
When YOU donate to Hadassah, it has a powerful e�ect:
“ Restricting Medical Research due to funding has very real human consequences, measured in loss of life and tremendous su�ering for patients and their families.” – Michael J Fox
• YOU make broken lives whole and keep crucial medical research moving forward
• YOU align yourself with a remarkable cause
• YOU give a transformational gift
Please give a gift that makes you
PROUD
All donations above $2 are tax deductible
YOU can give hope to millions of people worldwide
RANGE OF GIFTS
50,000.00
40,000.00
25,000.00
20,000.00
15,000.00
10,000.00
5,000.00
3,000.00
1,800.00
1,000.00
TOTAL
NUMBER OF GIFTS
1
1
2
3
5
8
10
12
12
50
$500,000 (125 Gifts)
How you can help us reach our target
RESEARCH
Hadassah Australia Head O¦ce
L1, 306 Hawthorn Road, Caulfield South VIC 3162
Hadassah Australia NSW O¦ce
Suite 602, 180 Ocean Street, Edgecli� NSW 2027
T: 1800 HADASSAH (1800 423 277)
www.stemneurologicaldisease.org
