What‟s Next for This Critical Partnership? · Stem Cell Bank & Registry The Center has invested...
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The Eds, Meds, and Industry: What‟s Next for This Critical Partnership? Newton Marriott Hotel June 17, 2011 #MassEconAC
Transcript of What‟s Next for This Critical Partnership? · Stem Cell Bank & Registry The Center has invested...
The Eds, Meds, and Industry:
What‟s Next for This Critical Partnership?
Newton Marriott Hotel
June 17, 2011
#MassEconAC
Jack Wilson, Ph.D.
President
University of Massachusetts
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The Massachusetts Innovation Ecosystem
Key ingredients for the innovation ecosystem:
Broad and deep knowledge-creating institutions
(universities, medical centers, other research institutions)
Global industry leaders in many technology sectors
Entrepreneurs and start-up companies
Investment capital (angel, VC and other) and related
expertise (legal, finance, etc.)
Incubators and institutions to accelerate growth (MIT’s
Deshpande Center, MA Tech Transfer Center)
Supportive public sector (innovation focused centers,
strategic investments, matching grants)
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Productivity of the Commonwealth’s Largest
Research Institutions (2008)
Research Expenditures
New Licenses Executed
Total Active Licenses
Start-up Companies
Created
Licensing Revenue
$4.35 B 443 3,536 58 $226 M
Includes: Boston University Beth Israel Deaconess Medical Center
Harvard University Brigham & Women’s Hospital
MIT Children’s Hospital Boston
UMass Dana-Farber Cancer Institute
MGH
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New Trends Emerging
From centralized corporate R&D to new kinds of industry/
university collaborations
From universities as independent actors to multi-institutional
partnerships for building infrastructure and attracting research
funding
From a primary focus on a traditional, disciplinary-focused
academic research agenda to one which also emphasizes
multidisciplinary problems and translation through applied
research, product development, and commercialization and use
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Pfizer Global Centers for Therapeutic
Collaboration
$100M investment over five years
New collaboration model for drug discovery and development
Partners include Beth Israel Deaconess Medical Center, Boston
University, Children's Hospital Boston, Harvard University,
Partners HealthCare, Tufts Medical Center, Tufts University
and the UMass Medical School
Boston is third U.S. site (San Francisco and New York), with
international sites to be added in 2012
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Massachusetts Green High Performance
Computing Center
Joint venture between UMass, MIT, Harvard, Boston U. and
Northeastern to build a shared high performance computing
center in Holyoke, MA ($95M construction cost)
Financial partners include the Commonwealth, Cisco and EMC
Center will expand computing infrastructure for universities,
promote research collaborations and industry partnerships
Will also catalyze regional economic growth and enable a
range of education partnerships in K-12 and with Springfield
Tech and Holyoke Community College
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UMass Innovation Institute
A new vehicle at UMass to create capabilities in applied
research, and enable development of new and innovative
products and services
Increases opportunities for external support and more
efficiently and effectively moves research to commercialization
and societal use
Multidisciplinary in focus and complementary to academic
research programs – especially UMass core strengths such as
materials science, information technology and clean energy
Launched as a pilot project at UMass Amherst with intent of
expanding across system over time
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Panel
David Bokoler, IBM Distinguished Engineer and Chief Technology
Officer, Emerging Internet Technologies, IBM Software Group
Mark Rice, Dean, School of Business, WPI
Ira Rubenzahl, President, Springfield Technical Community College
Susan Windham-Banister, President, Massachusetts Life Sciences
Center
Jack Wilson, President, UMass (moderator)
David Boloker, M.S.
CTO, Emerging Internet Technologies
IBM Software Group
© 2009 IBM Corporation
IBM in Massachusetts David Boloker CTO, Emerging Internet Technologies, IBM
IBM Emerging Internet Technology
© 2009 IBM Corporation
IBM in Massachusetts
Year IBM founded: 1911 (first MA office in 1914)
Largest IT consulting firm, 3rd largest tech company in New England.
Massachusetts IBMers’ job roles include software (65%), consulting (15%), and sales &
distribution (10%).
Local IBMers awarded 160 patents in 2010.
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Give back to the community
$1.9 million donated, 2009
18,000 volunteer hours, 2003
Major locations:
IBM Mass Lab, Littleton/Westford, largest software development lab in North America
Cambridge
Waltham
© 2009 IBM Corporation
Organic and Acquisitive Growth in MA
Local IBM clients
– Cape Cod Commission - 'Smart Cape Cod' project to improve water resrouces and the
environment
– Mass Water Resources Authority – IBM software manages $7B of production, facility
and fleet assets.
– UMass Memorial Healthcare, BlueCross BlueShield, Athletes' Performance, State Street,
National DCP (Dunkin Donuts), Staples, Caritas Christi, Acushnet Company, Constant
Contact, Northeastern U, B.U., UMass, MIT, WPI...
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18 acquisitions of MA companies since 2003
IBM in Massachusetts
© 2009 IBM Corporation
Key Focus areas in 2011
– Watson
– DIY Analytics
– Web Browser as an Application Platform
– Maqetta
– Mobile
– Accessiblity
How Do we do this?
– Create Technology from Scratch
– Open Source Collaborations
– Customer Proof of Concepts
– Joint Programs with Universities, Government and Corporations that are interested in a
particular technology or business area
How many people do this?
– Over 50+ researchers work in the Emerging Internet space WorldWide with about 10% in
Massachusetts
Some Key Boston Area Partnerships
– Universities: Northeastern, WPI, MIT, U of Massachusetts, Brown
– Institutions: Brigham & Woman’s, Children’s Hospital
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IBM Emerging Internet Technology
What does ET do?
Customer-centric Innovation - Technology Side
© 2009 IBM Corporation
IBM & Brigham & Woman’s Hospital Perspectives
Brigham & Woman‟s - Steven Seltzer, MD, Chairman - Dept of Radiology
As a leading academic medical center and a Radiology department that is committed to
innovation & research, we:
Actively seek intellectual partnerships with industry to: cross-fertilize ideas, do product
development and clinical evaluations providing enormous benefit to the hospitals,
industry partners and ultimately, our patients.
Our partnership with David Boloker and IBM in the arena of using advanced web-based
tools for information gathering, analysis and sharing, has catalyzed the development and
use of novel software tools that help us in clinical practice and in mining data from large
clinical trials.
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IBM Corporation
IBM‟s core values are dedication to every client‟s success, innovation that matters ( for the company and the world ) and trust and personal responsibility
This translates to many initiatives ranging from partnering with customers and others in
industry to working in Open Source. All of these help drive customer value through idea & technology creation, product development and research to benefit our customers.
IBM has many partnerships with local school boards including Early Learning Programs, TryScience, Boston Latin, Universities ( U. Mass, Northeastern, WPI, Boston University, Harvard, MIT, Brown University )
© 2009 IBM Corporation
IBM, BWH & COPDGene Partnership
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Workshop + 2500 cases - initial data reported available for individual and group review
Cloud contains save queries and researchers can select data based on multiple fields
COPDGeneTM Investigators can leave notes or define additional data collection
Video on COPD Desktop Application can be found here: http://www.youtube.com/watch?v=8gZk97-AuhQ
© 2009 IBM Corporation
Examples of Joint Work – COPDGene/BWH/IBM
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Mark P. Rice, Ph.D
Dean, School of Business
Worcester Polytechnic Institute
© 2011 Mark P. Rice
Key Question
How do we create a comprehensive, dynamic,
and highly effective ecosystem in which:
1 + 1 + 1 = 10
The MassEcon Annual Conference:
The Eds, Meds, and Industry Partnership
Agenda Items:
• Framework
• Case Examples
• What‟s next?
© 2011 Mark P. Rice
A Framework for an Effective Eds / Meds / Industry Partnership
Industry
Meds
Eds
The value exchange must be of sufficient intensity to make it worth engaging,
and the ROI needs to be significantly positive.
© 2011 Mark P. Rice
A Framework for an Effective
Eds / Meds / Industry Partnership
Industry
Meds
Eds
• Projects / Internships
• Working professional students
for degree and non-degree
programs
• Subjects for case studies
• Guest speakers
• PR value
• Talented hires
• Educational opportunities that
enhance (a) value of current
employees and (b) retention
• Consultants
• Research results / tech
transfer
• PR value Primarily
Customer –
Supplier
Relationships
© 2011 Mark P. Rice
Case Study #1:
Gateway Park
Gateway Park Life Sciences
and Bioengineering Center
($50+MM Investment
Strong partnerships with UMass
Medical, UMass Memorial,
and Fallon Healthcare
Ongoing research funded
by NSF, NIH, Veteran’s
Administration
Future home of the Bio-manufacturing
Education &Training Center and other Life
Sciences activities Fall 2012.
© 2011 Mark P. Rice
Case Study #2:
A WPI Major Qualifying Project (MQP)
Developing Benchmarks
for the Life Science Incubation Industry
Submitted to:
Massachusetts Biomedical Initiatives
© 2011 Mark P. Rice
Case Study #3:
Tech Transfer -- New Business Formation
Advanced Body Sensing – wearable
physiological sensors
Advanced Surface Technologies – platform
nanotechnology
ProcessIQ – Infra-red non-destructive
evaluation
ImagiSonix – ultrasound training
CellThera – cell de-
differentiation/regenerative tissue
applications
InsightMRI – high performance MRI coils
VivaScan – non-invasive glucose monitor
Securos – veterinary orthopedic supports
Five Star Technologies – semiconductor
materials processing
Critical Perfusion/Innovamedica – tissue
perfusion monitor
Reinhold Ludwig Ph.D.
Chief Scientific Officer and
Co-founder of InsightMRI.
Dr. Ludwig is a WPI Professor
of Electrical and Computer
Engineering with joint appt
in Biomedical Engineering
© 2011 Mark P. Rice
$2.25M in research grants from
the National Science Foundation
and the Veterans Administration
Center for e-Health Innovation and Process Transformation
Case Example #4: Research Center
PARTNERS
• UMass Medical
• UMass Memorial Health Care
• Fallon Community Health Plan
• Family Health Center of Worcester
• Veteran‟s Administration (New England Region)
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“The Knowledge Economy
as we know it
is being eclipsed by
something new – call it the
Creativity Economy.
The game is changing.
It is about creativity,
imagination, and above all,
innovation.” 1/
1/ Get Creative: How to Build Innovative Companies,
Business Week Special Report
A Perspective on the Future of the Eds / Meds / Industry Partnership
Innovation: The New Driver of Economic Development
© 2011 Mark P. Rice
Eds, Meds, and Industry:
What’s Next for this Critical Partnership?
Sustained Leadership in Eds, Meds and Industry Partners
Achieving critical mass sustainability
Key Success
Factors
Discovery Invention Innovation Entrepreneurship
THE
ECONOMIC
MARKET-
PLACE
The super-fluid flow of talent
Commitment to continuing innovation.
The creation and diffusion of intellectual property.
Acquisition / commitment of sufficient resources
Ira Rubenzahl, Ph.D
President
Springfield Technical Community College
Springfield Technical Community College
Factory of the Future
US manufacturing leads recovery
Professor John LaFrancis demonstrates the operation of a computer controlled milling machine at the Smith and
Wesson Center at STCC
Susan Windham-Bannister, Ph.D
President & CEO
Massachusetts Life Sciences Center
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The Massachusetts Life Sciences Center
MassEcon: The Eds,
Meds & Massachusetts
Industry: Partnering for
Economic Growth
June 17, 2011
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The Massachusetts Life Sciences Center: Who We Are and What We Do
Vision:
The Massachusetts Life Sciences Center administers the state‟s 10-year, $1B life sciences initiative. We develop and offer “best practice” programs that fund innovative economic development initiatives in the Massachusetts life sciences Supercluster, but also may have relevance for other technology sectors
Mission:
Serve as the “hub” of the Massachusetts life sciences Supercluster
Create jobs and drive economic development
Encourage innovation through investments in good science and good business
Strengthen and protect Massachusetts‟ global leadership position in the life sciences by supporting our academic medical centers, research institutions and universities; contributing to workforce development, and creating an industry-friendly environment
Accelerate the commercialization of promising treatments, therapies and cures
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MLSC Strategy Summary: Programs Tie Directly to Strategic Priorities
Vision and Mission
Focus Areas
Strategic Priorities
Programs, Products, Services
Impact
Programs:
Competitiveness: Faculty grants and infrastructure
Pipeline: Industry sponsored (translational) research; New Investigators, and Young Companies
Workforce: Internships; Equipment and Supplies for Training Programs
Infrastructure and Ecosystem: Capital Projects; Convening
Retention and Investment: Tax Incentives
Strategic priorities:
Competitiveness of the State’s academic institutions
Pipeline of new therapies, technologies, molecules, etc
Supply and distribution of life sciences workers with skills that are aligned with stakeholder needs
LS infrastructure and Ecosystem
Retention and growth of LS companies
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The Albert Sherman Therapeutics Center at the University of Massachusetts Medical School
The Center is contributing $90M toward a $405M therapeutics center. Projected to create thousands of jobs through direct construction spending, and 1,600 jobs through facility operation.
Examples of Life Sciences Center Investments
Life Sciences Center investments already have contributed to the creation of more than one million square feet of new laboratory and manufacturing space.
Stem Cell Bank & Registry
The Center has invested $9 million to support the creation of the Massachusetts Stem Cell Bank and International Stem Cell Registry at UMass Medical School.
Good Start Genetics
Good Start Genetics was awarded a $500,000 Accelerator Loan in 2009. Less then two years later the company raised $18 million in a Series A round, and paid back the Center‟s loan with interest.
Organogenesis in Canton
The Center provided a $7.4M grant plus tax incentives to retain Organogenesis and encourage their expansion in Canton. The expansion is projected to create 185 new permanent jobs, and will include the world‟s largest tissue manufacturing facility.
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Equipment & Supplies Matching Grant
Program for Skills Training and Education:
Awards grants of up to $250,000 per institution for
equipment and supplies that support life sciences
training
Awards made to 32 institutions across Massachusetts; $3.4 million investment
Over $600k in additional “matching” funds provided by industry sponsors
Supporting Workforce Development
Internship Challenge Program:
Funds interns working at companies with fewer than
100 employees– up to $7,200 for twelve weeks of
work
Program has placed more than 450 interns in paid internships over the past three summers
More than 55 of the participants have been offered full or part-time jobs at the conclusion of their internships
Program is now being expanded to operate on a year-round basis
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Cooperative Research Grants The Cooperative Research Grants encourage industry-sponsored research at
Massachusetts academic institutions and accelerate “bench to bedside.” The Center
has awarded 8 grants totaling $4.76 million.
Research Partners Award Recipient Award Research
UMass Lowell/
Boston Scientific Dr. Rudolf Faust
$199,596 per year
for three years Novel polymer biomaterials
Immune Disease Institute/ Epic
Therapeutics Dr. Judy Lieberman
$250,000 per year
for three years
An siRNA-based
microbicide
Harvard School of Engineering and
Applied Sciences/
Rain Dance Technologies
Dr. David Weitz $250,000 per year
for three years
Development of a functional
fluorescent-activated cell
sorter
Massachusetts General Hospital/
Idera Pharmaceuticals Dr. Andrew Luster
$63,100 per year
for three years
Targeting of toll-like
receptors in A.I.D.
Brigham & Women’s Hospital/
Biomeasure
Dr. Richard Lee
Dr. Prath Patwari
$250,000 per year
for three years
Design and testing
of a new regenerative
protein for delivery
UMass Medical School/
Rxi Pharmeceuticals
Dr. Michael Czech
Dr. Gary Ostroff
$249,593 per year
for three years
Development of
orally-delivered RNAi
therapeutics
MGH/Philips Healthcare Dr. Qianqian Fang $250,000 per year
for two years
Combined optical and
mammographic imaging
device
UMass Medical School/RXi
Pharmaceuticals Dr. Robert Brown
$250,000 per year
for two years
ALS treatment using
“selfdelivering rxRNA”
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The “Bottom Line” Life Sciences Center‟s Impact: June „08 – June „11
• Corporate Investors
• NIH
• Private
Foundations
• Institutes
• Other Private Investors
• Academic Institutions
Grants to Academic Organizations and Medical Centers
Grants for “Shovel
Ready” Capital
Projects
Investments in
Life Sciences
Companies
Public Dollars Invested
= $215.8 M
Matching Investments Attracted = $706 M
3 X multiplier
• Permanent
Job Potential = 7,038
• Building Trades
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Keeping in Touch
www.masslifesciences.com • News updates
• Program Information
• Application portal
Life Sciences Center Email List • 3,500 recipients
• Weekly event listings
• Sign up today!
The Eds, Meds, and Industry:
What‟s Next for This Critical Partnership?
Newton Marriott Hotel
June 17, 2011
#MassEconAC
