Welcome to the 2 Sino-German Symposium · Welcome to the 2nd Sino-German Symposium We are very...

Welcome to the 2nd Sino-German SymposiumWe are very pleased to welcome you to the 2nd Sino-German Symposium on Singlet oxygen and photodynamic effects.

About 27 scientists from PR China, 22 from Germany, one special speaker from USA, one from Ireland and two from Brazil will report about their latest results in singlet oxygen research.

The symposium is dedicated to different aspects of singlet oxygen research, starting with fundamental questions of photosensitized generation and direct detection of singlet oxygen. We devote particular attention to the question of 2nd and 3rd generation photosensitizers for clinical use. This time, amongst clinical aspects, two sessions are dedicated to the photodynamic inhibition of microorganisms. The exciting topic of using singlet oxygen luminescence as a tool for optimization of photodynamic treat-ment in situ will be discussed on the symposium, too.

We would like to thank all of the participants – including our excellent students – for their substantial contribution towards making the symposium successful.

We hope that by experiencing the open atmosphere of this meeting you will get new insights and learn more about the fascinating new prospects of using the photodyna-mic effect. This 2nd symposium should give all of us new impulses, inspirations and the basis for new scientific and social contacts to create and develop new networks.

We will spare no effort to make the symposium informative and inspiring for you and hope, that you will have an enjoyable week in Berlin.

Prof. Beate RöderGerman ChairHumboldt-Universität zu Berlin

Prof. Buhong LiChinese ChairFujian Normal University

Chinesisch-DeutschesZentrum fürWissenschaftsförderung

中德科学中心

1 - Schedule

8 - Participants

21 - Contact Information

24 - About Berlin

Contents

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Second Sino-German Symposium on Singlet Molecular Oxygen and Photodynamic Effects

Schedule

29. May 2017: Registration

30. May 2017

8:45 - 9:15

Opening Ceremony

Buhong Li, Fujian Normal University, ChinaBeate Röder, Humboldt-Universität zu Berlin, GermanyNorbert Koch, Director of the Department of Physics, Humboldt-Universität zu Berlin

9:15 - 9:45Hans-Peter Berlien

History of PDT - from an ancient technique to the future

Ev. Elisabeth-Klinik, Lasermedizin

Session 1 Singlet OxygenChairs: Ying Gu, Alexander Greer

9:45 - 10:10Jan Schlothauer

Prospects and limits of singlet oxygen luminescence detection

Instituto de Química, Uni-versidade de São Paulo

10:10 - 10:35Steffen Hackbarth

Singlet oxygen luminescence parameters in hetero-geneous environment and in vivo

Humboldt-Universität zu Berlin, Institut für Physik

10:35 - 11:05 Coffee Break

11:05 - 11:30Martina Meinke

EPR detection of singlet oxygen induced ROS in skin

Charité-Universitätsmedizin Berlin, Klinik für Dermato-logie, Venerologie und Allergologie, Bereich Haut-physiologie

11:30 - 11:55Angelika Rück

Correlated FLIM and PLIM for cell metabolism and oxygen sensing

Core Facility für konfokale und Multiphotonen Mikros-kopie, Universität Ulm N24

11:55 - 12:20Michael Köhl

Properties and usage of water after quenching of singlet oxygen

Division Solar Thermal and Optics,Fraunhofer-Institut für Sola-re Energiesysteme ISE

12:20 - 12:45Maurício S. Baptista

Photosensitization reactions at membranesInstituto de Química, Uni-versidade de São Paulo

12:45 - 13:45 Group Photo and Lunch Break

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Session 2Singlet Oxygen Generation and DetectionChairs: Pengfei Wang, Steffen Hackbarth

13:45 - 14:10Beate Röder

Singlet oxygen luminescence in cell suspensions as measure of the photodynamic effect


14:10 - 14:35Michael Pfitzner

Time resolved singlet oxygen measurements in CAM model and mice


14:35 - 15:00Tobias Bornhütter

Time resolved singlet oxygen luminescence measu-rements on surfaces with algae, bacteria and fungi



Session 3Photosensitizers and targeting carrier systems: part IChairs: Daxiang Cui, Wolfgang Bäumler

15:30 - 15:55Rüdiger Faust

Photosensitization with TiO2/phthalocyanine-hyb-rids

Universität Kassel, FB10 Mathe-matik und Natur-wissenschaften, Institut für Chemie

15:55 - 16:20Pengfei Wang

Carbon dots based phototheranostic agents

Technical Institute of Physics and Chemistry of the Chine-se Academy of Sciences

16:20 - 16:45Thomas Gensch

Flavin binding fluorescent proteins as genetically encoded photosensitizers

Institut für Komplexe Syste-me 4, Zelluläre Biophysik, FZ Jülich

16:45 - 17:10Gang Liu

Biomimetic synthesis of nanoliposomes as cancer theranostics

School of Public Health, Xiamen University

17:10 - 17:35Guangjun Nie

Nanotechnoligcal approaches for improved photo-dynamic therapy

National Center for Na-noscience and Technology, China

19:30 - 21:30 Dinner

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31. May 2017

Session 4 Photosensitizers and targeting carrier systems: part IIChairs: Zhihua Ding, Rüdiger Faust

8:35 - 9:00Jürgen Lademann

Protection of antioxidants against destructive action of reactive oxygen species (ROS) in human skin

Charité Berlin, Klinik für Dermatologie, Venerologie und Allergologie, Bereich Hautphysiologie

9:00 - 9:25Mathias Senge

Reversible singlet oxygen binding dyes as therano-stic agents

Biomedical Sciences Institu-te, SFI Tetrapyrrole Laborato-ry, Trinity College Dublin

9:25 - 9:50Tymish Y. Ohulchanskyy

Nonlinear Upconversion of Near-Infrared Light to Enable Cancer Therapy

College of Optoelectronic Engineering, Shenzhen University

9:50 - 10:15Yueqing Gu

Upconversionalnanoplat for deep tissue PDTSchool of Engineering,China Pharmaceutical University

10:15 - 10:40Xiaolong Liu

Smart Nanomaterials for synergistically enhancing photodynamic therapy efficiency

Mengchao Hepatobiliary Hospital of Fujian Medical University


Session 5 Photosensitizers and targeting carrier systems: part IIIChairs: Yueqing Gu, Mathias Senge

10:55 - 11:20Daxiang Cui

Multifunctional nanoprobes for targeted photoa-coustic imaging and therapy

Shanghai Jiaotong Universi-ty/Institute of Nano Biome-dicine and Engineering

11:20 - 11:45Yanchun Wei

Nano-photosensitizer for precisely Controlled photo-dynamic therapy

MOE Key laboratory of Laser Life Science, College of Biophotonics, South China Normal University

11:45 - 12:10Zhenxi Zhang

Metal Nanomaterial - Photosensitizer conjugates for PDT

School of Life Science and Technology, Xi’an Jiaotong University

12:10 - 12:35Jianzhang Zhao

Preparation of new Photosensitizers and Study of the Photophysical Properties

State Key Laboratory of Fine Chemicals / School of Che-mical Engineering, Dalian University of Technology

12:35 - 13:00

Jing Xin

The effective ways to improve the anti-proliferative activities of AlPcS4 by photodynamic therapy in gastric cancer cells

School of Life Science and Technology, Xi‘an Jiaotong University

13:00 - 14:00 Lunch Break

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Session 6PDI of microorganisms: part IChairs: Guangjun Nie, Arno Wiehe

14:00 - 14:25

Tim Maisch

The impact of absorbed photons by different photosensitizers relating to the efficacy of PDI of microorganisms

Antimicrobial PDT and Cold Plasma Klinik und Poliklinik für Dermatologie Universi-tätR egensburg

14:25 - 14:50

Ying Wang

Selective killing effect of helicobacter pylori by a novel pyridyl cationic-modified benzyli-denecyclopentanone photosensitizer

Department of Laser Medi-cine, Chinese PLA General Hospital

14:50 - 15:15

Annegret Preuß

Cationic phosphor corrols - universal agents for PDI against microorganisms



Session 7PDI of microorganisms: part IIChairs: Dan Zhu, Tim Maisch

15:45 - 16:10Wolfgang Bäumler

Natural photosensitizer molecules for antimicrobial PDT

Klinik und Poliklinik für Dermatologie, Universität Regensburg

16:10 - 16:35

Arno Wiehe

Conjugates of porphyrins and hyperbranched polyglycerol for the photodynamic inactivation of bacteria

Biolitec AG

16:35 - 17:00Jakob Pohl

PDI of phototrophic micro-organisms - from planc-tonic cells to biofilms


17:00 - 17:25Alexander Müller

PDI of microorganisms via functionalized microfilt-ration membranes


17:25 - 17:50Nedaa Shamali

Towards photodynamic treatment of onychomycosis: photodynamic inactivation of dermatophytes


17:50 Laboratory Tours

19:30 - 21:30 Dinner

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01. June 2017

Session 8Optical monitoring techniques for photodynamic therapy and dosimetryChairs: Jianzhang Zhao, Beate Röder

8:35 - 9:00Buhong Li

Optical techniques for monitoring photodynamic therapy

School of Photonics and Electronic Engineering, Fuji-an Normal University

9:00 - 9:25Dan Zhu

In vivo Tissue Optical Clearing: A Potential Technique for PDT

Wuhan National Laboratory for Optoelectronics

9:25- 9:50Zhihua Ding

Optical coherence tomography for monitoring pho-todynamic therapy

Wuhan National Laboratory for Optoelectronics

9:50 - 10:15Lisheng Lin

Monitoring blood flow responses for artery and vein during vascular targeted photodynamic therapy


10:15 - 10:40Xianglian Liao

Quenching effects of EGCG on photosensitized luminescence in the tissue simulating phantom



11:00 - 11:25Jing Wang

Hyperspectral imaging for fluorescence dosimetry in PDT


11:25 - 11:50Ronald Sroka

Theoretical considerations on self - shielding effect during PDT

Laser-Forschungslabor / LIFE-Zentrum, Klinikum der Universität München, Cam-pus Großhadern

11:50 - 12:15Adrian Rühm

Therapy planning and monitoring of interstitial PDT

School of Life Science and Technology, Xi’an Jiaotong University

12:15 - 12:40

Huiyun Lin

Assessment of signal acquisition mode impact on time-resolved sensitized singlet oxygen measure-ment


12:40 - 13:45 Lunch Break

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Session 9New aspects in clinical PDTChairs: Buhong Li, Hans-Peter Berlien

13:45 - 14:10

Alexander Greer

Pointsource Photodynamic Therapy: Fiber Optics and 3D Printed Sensitizer Tips for High Precision Eradication of Cancer Cells

Department of ChemistryCity University of New York, Brooklyn College, USA

14:10 - 14:35Herbert Stepp

PDT response of cancer stem-like cells

Laser-Forschungslabor/LIFE-Zentrum, Klinikum der Universität München, Cam-pus Großhadern

14:35 - 15:00

Georg Daeschlein

PDT in skin and wound antisepsis in the postanti-biotic era: possible indications and clinical advanta-ge

Department of DermatologyUniversity of Greifswald


15:30 - 15:55Ying Gu

Clinical treatment of port wine stains

Department of Laser Medi-cine, Chinese PLA General Hospital

15:55 - 16:20Sijia Wang

Light-controlled delivery of Photo-immune conjuga-tes for molecular targeted PDT


16:20 - 16:45Sviatlana Kalinina

Oxygen sensing PLIM together with NAD(P)H-FLIM for metabolic mapping in living cells and tissues

Core Facility für konfokale und Multiphotonen Mik-roskopie, Universität Ulm N24/4

16:45 - 17:10

Xuelin Xu

Quantitative evaluation of vasoconstriction by image processing for vascular targeted photodynamic therapy


17:10 - 17:35Cuiping Yao

Nanoparticle aided PDT

Xi‘an Jiaotong UniversitySchool of Life Science and Technology

17:35 - 18:00Concluding Remarks – aspects of future collaboration

Beate Röder, Humboldt-Universität zu Berlin, GermanyBuhong Li, Fujian Normal University, China

19:30 - 21:30 Dinner

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02. June 2017: Academic visiting and scientific discussion

9:00 Departure at the hotel (by bus)

10:15 Arrival in Portsdam, walk in the park of Sanssouci

11:45 Arrival at the New Palace

12:00Walk in the New GardenLunch in the restaurant Meierei Potsdam

14:30 Departure back to Berlin (by bus)

15:30 Arrival at Alexanderplatz

16:00 Visit of the TV-Tower

17:00 Departure from Alexanderplatz (by bus)

18:00 Arrival at the ship Bon Ami on river Spree, Dinner

21:00 Departure to the hotel (by bus)

03. June 2017: Departure day

Sanssouci New Palace

TV-Tower Ship Bon Ami on the river Spree

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中德科学中心

German Participants

Beate Röder is professor for experimental physics at the Department of Physics, Humboldt-Universität zu (HU) Berlin since 1992. She is leading the photobiophy-sics group and supervised about 20 PhD students. She received her PhD degree in Experimental Physics from HU Berlin in 1982 and the habilitation in 1986. Her re-search focuses on molecular photobiophysics, especially on fundamental research in the field of photosensitization and artificial photosynthesis. Beside these topics her research was and is focused on the development of time-resolved optical methods for detection of very low light intensities. She works more than 30 years on direct spectroscopic detection of singlet molecular oxygen, the last years in particular on time-resolved luminescence detection. In 1986 she was awarded with the Humboldt Research Price for her habilitation in the field of fundamental research on mechanis-ms in PDT. 1989 she was a visiting scientist at Bowling Green State University (USA) in the group of Michael Rodgers, one of the pioneers in singlet oxygen luminescen-ce detection. In the 90is she also visited the Weizmann Institute in Israel (Prof. A. Scherz, Prof. Y. Salomon), In 2009 she was awarded with a Walton Professorship by Science Foundation Ireland.

Volkhard May is Privatdozent for Theoretical Physics at the Department of Physics, Humboldt-Universität zu Berlin since 1997. He is the head of a group focusing on the theory of charge and energy transport in molecular systems. About 15 PhD students have been supervised by him. His PhD degree in Theoretical Physics received from the Humboldt-Universität zu Berlin in 1981, and he got the habilitation in 1987 from the College of Education at Güstrow. His research focuses on Theoretical Chemical Physics, especially on photoinduced kinetic phenomena in nanosystems formed by molecules, semiconductor nano-crystals and metal nano-particles. His actual interest is on different mechanisms to achieve an enhancement of singlet oxygen lumine-scence. In 1981 he was awarded by the Humboldt Price for his PhD thesis.

Steffen Hackbarth received his Ph.D. degree in experimental physics from HU Berlin in 2000. Ever since, he was working in the field of time-resolved spectroscopy in the time range ps to ms with a special focus at the triplet processes of photosensitizers. He is member of the photobiophysics group and scientist in charge for the singlet oxygen lab and especially the highly sensitive singlet oxygen detection. He co-super-vised one Ph.D. and several Master/ Diploma students. Since 2011 he is leader of the advanced practical courses for the physics students at HU-Berlin. His research focu-ses on molecular photobiophysics, especially on fundamental research in the field of photosensitization and energy transfer processes in multi-chromophoric systems designed for Photodynamic therapy as well as singlet oxygen luminescence detec-

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tion at highest sensitivity.In 2012 he was awarded (together with his colleague, Jan Schlothauer) with the innovation award of the SPIE Europe for the development of a compact time-resolved table-top singlet oxygen luminescence detection system.

Annegret Preuß is scientific assistant in the photobiophysics group led by Professor Beate Roeder in the Department of Physics, Humboldt-Universität zu Berlin. Since her diploma in Biophysics 2007 she is working in this group in the field of in vitro experiments for Photodynamic Therapy. She received her PhD degree in 2011 for in vitro investigation of biodegradable nanoparticles as drug carrier for the Photodyna-mic Therapy. The PhD thesis was part of the German-Chinese joint research project “NanoCancer” funded by the German Federal Ministry of Education and Research. During her PhD she spend 6 month in the Group of Mathias O. Senge in the Institute of Molecular Medicine at the Trinity College Dublin, Ireland. 2010 she chose a new focus for her research: The Photodynamic inactivation of microorganisms. Starting with the Photodynamic inactivation of bacteria (PIB) the interest spread to various microorganisms relevant in medical and environmental research. A special focus is the investigation of Photodynamic inactivation of mold fungi and their conidia.

Wolfgang Bäumler is professor for experimental dermatology at the Department of Dermatology, University Hospital of Regensburg in Germany since 2008. He studied physics at the University of Regensburg and graduated with a diploma 1987. The topic of his PhD thesis was spectroscopy of dye molecules using femtosecond lasers. After his PhD thesis he moved to the medical faculty in 1992 and is working in dif-ferent fields of laser medicine and photodynamic therapy to date. He gained much expertise in detecting singlet oxygen by its very weak luminescence signal. Singlet oxygen is a major species to kill tumor cells or pathogenic microorganisms. He is collaborating with scientific partners in Germany, European countries and the Uni-ted States. At present he focussed on the development of a sustainable antimicrobial photodynamic therapy that kills pathogenic and multiresistant bacteria using natural photosensitizers.

Tim Maisch studied Biology at the Univ. of Erlangen-Nuremberg, Germany. In 1997 he received his diploma and achieved his Ph.D. with a thesis titled „Upregulation of protein expression on endothelial cells infected with human cytomegalovirus” in 2001. Since 2002, he has been working as postdoctoral fellow at the Dept. of Der-matology, University Hospital of Regensburg on photodynamic inactivation of mul-ti-resistant bacteria. Main objectives are to investigate the role of singlet oxygen and oxygen consumption in photodynamic inactivation of bacteria as well as the detection of singlet oxygen directly by its luminescence. One focus is the development of new photosensitizers for the photodynamic treatment of bacterial and fungal infections.

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中德科学中心

A second focus in cooperation with the Max-Planck-Institute for Extraterrestic Phy-sics (MPE) is the application of cold atmospheric plasma against microorganisms. He gained his Postdoctoral Habilitation in 2009 (venia legendi). He is a member of the American Society for Microbiology. Since 2006, he achieved several Awards to support the research interest in antimicrobial photodynamic therapy (e.g. “PDT-2006 Award”to support the research interest in photodynamic therapy and fluorescence diagnosis of skin diseases and “9th Arnold-Rikli-Award” to support photo-biological research interests of light in relation to human medicine in the future).

Hans-Peter Berlien graduatied from the faculty of medicine at the Freie Universität Berlin in 1976 and became medical assistant at the University Clinic Berlin Steglitz where he certified as a physician, started his surgical education and received his doc-torate specializing in paediatric surgery in 1981. Since 1985 he is medical director of the Centre for Laser and Medical Technology Berlin (LMTB). After his postdoctoral lecturing qualification he became professor for laser medicine at the Freie Universität Berlin in 1989. From 1996 to 2005 he has been head of department for laser medicine at the Klinikum Berlin Neukölln now belonging to Vivantes. As head of department, he transferred the whole department to the Elisabeth Klinik Berlin in 2005 where he still is. He is aFellow of the National German Academy for Technical Sciences (aca-tech), Fellow of the New York Academy of Sciences, Convener of the Working Group Laser in Medicine of the International Standardization Organization, Past President of the International Society for the Study of Vascular Anomalies ISSVA, and Head of Working Group Quality and Certification of the German Laser Medicine Society.

Jürgen Lademann is an internationally renowned scientist researching at the inter-face between dermatology, pharmacology and biophysics. Since 1996 he has been in charge of the Center of Experimental and Applied Cutaneous Physiology at the Department of Dermatology, Venerology and Allergology of the Charité - Universi-tätsmedizin Berlin. In 2001 he was appointed professor of dermatology. His research topics include skin penetration pathways of topically applied substances, hair follicles as penetration pathway and reservoir of drugs, and antioxidant measurements. Jür-gen Lademann is member of numerous committees and editorial boards of various journals, such as Skin Pharmacology and Physiology. From 2003 through 2008 he was President of the International Society of Skin Pharmacology and Physiology. In 2008, he joined the Cosmetics Committee of the Federal Institute of Risk Assess-ment (Germany), was appointed expert for risk assessment of nanoparticles in cos-metic products with ECETOC AISBL, of Brussels, and reviewer for various research programs of the European Union. In 2010 he was appointed member of the Light Engineering Standardization Committee, Section “Radiology”, with the German In-stitute for Standardization (DIN – Deutsches Institut für Normung e. V.). In August,

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2011 he chaired the Gordon Conference „Barrier Function of Mammalian Skin“ in the United States. In 2012 he was admitted member of the Berlin-based scientific society Leibniz Sozietät der Wissenschaften.

Martina C. Meinke is professor at the Center of Experimental and Applied Cutaneous Physiology of the Dept. of Dermatology, Venerology and Allergology, Charité - Univer-sitätsmedizin Berlin since April 2016. She studied chemistry at the Free University of Berlin and did her PhD in 1994 with a research stay at the University of Sherbrooke, Québec, Canada. Afterwards she managed a laboratory for environmental analysis until 1999. Then she switched to the medical diagnostics field worked at the De-partment of Dermatology of Charité and the Laser- und Medizin-Technologie Berlin. 2006 she finished her postgraduate studies of Medical Physics and since 2007 she has been assistant professor at the Charité- Universitätsmedizin Berlin. Her research fields are optical and spectroscopic methods to determine skin physiological parame-ters with main focus on electron paramagnetic resonance spectroscopy.

Ronald Sroka is the head of the Laser-Forschungslabor (LFL) (Laser-Research Labo-ratory ) at LIFE-Centre of University Hospital Munich) since 2010. As physicist he received PhD degree at the Medical Faculty of the University Munich in 1992 and habilitation in 2014. Since 1986, he was mostly engaged in the research and develop-ment of fluorescence diagnosis, Photodynamic Therapy (PDT) and laser surgery in nearly all medical disciplines focusing on the translational technical implementation of several laser applications into the clinics (e.g. Urology: laser lithotripsy, PDT of pro-state cancer, BPH vaporization and enucleation; ENT: laser assisted tonsillotomy and nasal applications; phlebology: endoluminal laser ablation of varicose vein; GI: PDT of Barrett cancer). R. Sroka gained experience in project management as principal in-vestigator with several national bi- or multilateral projects, as well as interdisciplinary and translational research projects of clinical relevance. He is the General Secretary of the German Society of Lasermedicine (DGLM e.V.), EiC of Photonics and Lasers in Medicine, member of the steering committee World of Photonics Munich, organizer, co-organizer and chair of several international and national conferences. Since 2015 he held an adjunct professorship at Tongji University Shanghai – School of Medicine and is with the advisory board of the Institute of Photomedicine at Tongji University.

Adrian Rühm is working as a senior scientist at the Laser-Forschungslabor (LFL) at the LIFE Center of the University Hospital of Ludwig-Maximilians University (LMU) in Munich. He is specializing in photodynamic therapy and fluorescence diagnosis. He received his PhD degree in Experimental Physics from the University of Wupper-tal in 1998. He has been working in materials science at the Max Planck Institute for Metals Research in Stuttgart, Germany, for the Massachusetts Institute of Technolo-

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gy, Boston, MA, USA at the Argonne National Laboratory, Argonne, IL, USA, and at the research neutron source FRM-II in Garching, Germany, until he joined the LIFE Center in 2011. His research is focussed on PDT dosimetry, PDT monitoring, and fluorescence-guided surgical and endoscopic interventions, as well as luminescence lifetime-based tissue diagnosis. He has been studying interactions of light and radi-ation with matter for more than 20 years. In 2005, he was an adjunct professor at Sogang Univerity, Seoul, Korea.

Herbert Stepp is research group leader at the Laser-Forschungslabor, LIFE-Center, Urology Department of the Hospital of the University of Munich (Ludwig-Maximili-ans-University). Since 1993 he is leading this group with a focus on biophotonics for clinical applications. He received his Diploma in Physics in 1984 and his PhD degree at the Medical Faculty of the Ludwig-Maximilians-University in 1993. His interest lies in the introduction of novel laser and light applications to improve clinical diagnosis and treatment. In close collaboration with different clinical departments, equipment and procedures based on fluorescence spectroscopy and imaging were developed. Clinical trials resulted in meanwhile worldwide approvals for fluorescence guided resection of urinary bladder cancerand brain tumor. Treatment of malignant disease based on phototoxic reactions of selectively accumulating sensitizers was also studied and evaluated in various disciplines, where the current focus is on the establishment of the procedure to treat malignant brain tumors with a stereotactic approach. Ano-ther current focus is on the non-invasive detection of iron-deficiency. Herbert Stepp has published more than 100 peer-reviewed scientific papers with a Hirsch-index of currently 33 and is co-inventor of 20 patent applications.

Michael Köhl is senior scientist at the Fraunhofer Institute for Solar Energy Systems since 1989. He is acting as project coordinator of national, European and interna-tional research projects in the framework of the International Energy Agency and supervising master -, bachelor- and PhD-students. The present focus of the work is on the long-term durability of materials interacting with radiation and exposed to we-athering. Here he can make use of his long-term experinces on coating technologies and optical characterization methods. He received his Diploma in Physics from the University of Stuttgart and the PhD in Electrical Engineering from the University Hagen. During his activities related to singlet oxygen he investigated vacuum deposi-tion of phthalocyanines, optical detection of singlet oxygen, the interaction of singlet oxygen with water and plants.

Rüdiger Faust is professor of organic chemistry and holder of the Chair „Chemistry of Mesoscopic Systems“ at the University of Kassel since 2003. After receiving his diplo-ma in chemistry from the Technical University Dortmund he joined Prof. Peter Voll-

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hardt’s group at the University of California at Berkeley, USA and completed his PhD in chemistry in 1993. From there he moved to the ETH Zürich for a postdoctoral stint with Prof. François Diederich. In 1995 he accepted his first independent position at the University of Heidelberg and started his research in the chemistry and properties of phthalocyanine-type compounds. In 1998 he was appointed Senior Lecturer in Chemistry at University College London, UK, a post he held until 2003. At the Uni-versity of Kassel, the Prof. Faust established a physical-organic research group that investigates issues related to chemical light-energy conversion with functional orga-nic molecules. Relying on methods of modern organic synthesis the group explores the chemistry and the photophysics of phthalocyanines and their synthetic analogues and modifies them for efficient energy and electron transfer processes. To this end, often inorganic-organic hybrid systems with relevance to, inter alia, dye-sensitized solar cells, photocatalytically and photodynamically active materials and biosensors are prepared. The group profits from its association with the Nano research center CINSaT (Center for Interdisciplinary Nanostructure Science and Technology) at the University of Kassel and conducts research related to the organic functionalisation of nanoparticular semiconductors and to the development of photo-switchable organic nanowires. Since 2013 Prof. Faust serves as Dean for the Department of Mathematics and Natural Sciences at the University of Kassel.

Georg Daeschlein received the Doctorate of Medicine (M.D.) from the Christian-Al-brechts-Universität Kiel, Kiel, Germany 1985. Specialization in Laboratory Medicine (1992), Microbiology and Epidemiology (1995), Hygiene and Environmental Medicine (2005) and Dermatology and Venereology (2014) in Greifswald, Ernst-Moritz-Arndt University, Greifswald, Germany. Registrar and head of dermatologic laboratory (Pri-vate Docent) since 2006 at Department of Dermatology at the Ernst-Moritz-Arndt University of Greifswald, director Prof. Dr. med. Michael Jünger. Habilitation in wound dermatology and infection prevention in 2011 at University of Greifswald. Cli-nical and scientific topic: wound management, infection prevention, multiresistant bacteria, plasma and physical medicine.

Angelika Rueck studied chemistry at the University of Ulm, where she made her PhD in Physical Chemistry, in 1995. She is actually the leader of the core facility con-focal and multiphoton microscopy of the medical faculty of the University Ulm. She is responsible for microscopic applications in the field of biomedical research. Her specialties are developments of methods for spectral and time resolved fluorescence lifetime imaging and phosphorescence lifetime imaging based on time correlated single photon counting in combination with laser scanning microscopy for detection and dynamic analysis of cell metabolism and oxygen sensing during carcinogenesis as well as neurodegenerative diseases. Besides, imaging of living cells by confocal

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Raman microscopy is another focus in her research. In 1997 she received the Felix Wankel award for the development of the non-animal CAM model in dermatological research. She is nominated for the Otto von Guericke award 2016.

Sviatlana Kalinina is a biophysicist with a background in both physics and cell physio-logy. She got her diploma at Belarusian State University (Belarus) and made her PhD at Karlsruhe Institute of Technology (Germany). She currently works as a scientist at University of Ulm (Germany) within a microscopy research group focused on fluore-scence lifetime imaging for the investigation of cellular metabolism.

Thomas Gensch studied pysics at the Humboldt-Universität zu Berlin and made his PhD in Biophysics at Heinrich-Heine-University Düsseldorf/Max-Planck-Institute of Radiation Chemistry Mülheim/Ruhr. He received the Casimir-Ziegler Award of the Royal Dutch Academy of Science and the Nordrhein-Westfälische Academy of Scien-ce (1997) and won a personal Marie-Curie Postdoc-Grant (1998-1999; Catholic Uni-versity Leuven, Belgium). The scientific career of Dr. Gensch started in time-resolved optical spectroscopy and investigation of photophysics of organic dyes and prosthetic groups bearing chromoproteins like phytochromes, rhodopsins, LOV-domains and photosynthetic complexes. In his Postdoc stays at Leuven University (Prof. Frans De Schryver; Department of Chemistry) and Amsterdam University (Prof. Klaas Hel-lingwerf; Dp of Chemistry) he worked successfully in newly emerging research fields like single molecule fluorescence microscopy and time-resolved protein structure determination. Since he joined Forschungszentrum Jülich he focused his research on development advanced fluorescence microscopy techniques among them FLIM, FRET microscopy and single molecule localization microscopy (PALM, dSTORM) and their use to study cell biological and physiological topics in living cells and brain tissue. More than 15 years of investigation, development and application of genetically encoded fluorescent markers and sensors made him an expert in all aspects of fluore-scent proteins. In the past 5 years part of his scientific interest was redirected back to singlet molecular oxygen generation in solution and cells and phototoxicity in general especially in his work related to LOV-domain derived fluorescent proteins (FbFPs).

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Chinese Participants

Buhong Li is a professor of Biomedical Photonics and the associate dean for School of Photonics and Electronic Engineering, Fujian Normal University, Fuzhou, China. He received his PhD degree in Optical Engineering from Zhejiang University in 2003. He was the New Century Excellent Talents in Ministry of Education of China since 2009. He was a visiting scientist in the Ontario Cancer Institute and University of To-ronto from September 2005 to September 2007. He then worked as a senior visiting fellow in Institute of Physics of Humboldt University of Berlin from April 2014 to August 2014. His research focuses on optical method and apparatus for monitoring photodynamic therapy dosimetry, in particular for the spatiotemporal detection of singlet oxygen luminescence. He has authored more than 80 publications and recei-ved 4 patents. He is the editorial members of Journal of Innovative Optical Health Sciences, Photonics& Laser in Medicine, and Acta Laser Biology.

Daxaing Cui is a distinguished professor of Shanghai Jiaotong university, vice dean of Translational Medicine Research Institute of Shanghai Jiaotong University, the head of Nano-Biotechnology Research Institute, Assistant Dean of Institute of micro-and nano-technology, PhD supervisor, Deputy Director of the key laboratory of thin-film micro-technology, winner of the National Fund for distinguished young scholars, Chief Scientist of Nano major scientific research projects. Achieve the Bachelor of medicine degree at the Second Military Medical University in 1990, the Master‘s de-gree in medicine at the Fourth Military Medical University in 1995, the PhD in Bio-chemistry and molecular biology in 1998. Work in the institute of gene diagnosis technical application Research of the Fourth Military Medical University and been promoted to associate professor in 2000. He achieved postdoctoral fellow Germany Max Planck Institute between 2001 and 2004. He was involved in the formation of bio-nano-engineered of Max Planck Center and got the qualifications of Germany Project Manager and bio-safety management certificates. He was responsible for the bio-safety of bio-nano-engineered center, and the head of bio-nano lab group. After returning to China in September 2004, he was hired as a professor of Institute of micro-and Nano-Science and technology of Shanghai Jiaotong University and set up nano-bio-engineering research center and has been the Director of the Research Of-fice. Get the honour of Shanghai Pujiang talent in 2006, new century excellent ta-lents of the Ministry of Education in2008 and the Shanghai excellent academic leader in 2009. He was Japan‘s Waseda University visiting professor from September 2007 to March 2008. Research interests: nano-materials synthesis, biological effects and safety evaluation; the early diagnosis system of tumors based on nano-particle mar-king and nano-particle effects, multifunctional Nano-Probes and molecular imaging; tumor-related genes and protein structure and function; CIK and stem cell therapy; efficient gene or drug delivery systems.

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中德科学中心

Zhihua Ding is a professor of Optical Engineering and the director of institute of laser biomedicine at Zhejiang University, Hangzhou, China. He received his PhD degree in Optical Engineering from Shanghai institute of optics and fine mechanics (Chinese academy of sciences) in 1996. He was a temporary lecturer at Venture Bu-siness Laboratory, Shizuoka University, Japan from November 1998 to April 2000, and a senior postdoctoral fellow at Beckman laser institute, University of California, Irvine, USA from June 2000 to September 2002. He was selected as the New Cen-tury Excellent Talent of the Ministry of Education of China in 2004. His research focuses on optical coherence tomography and biomedical applications. He has autho-red more than 100 journal papers and over 30 patents. He is an editorial member of Journal of Innovative Optical Health Sciences, Frontiers of Optoelectronics, Chinese Journal of Lasers, Journal of Lasers, Optics & Photonics, and an associated editor of Acta Laser Biology.

Ying Wang is an associated chief physician in the Department of Laser Medicine of Chinese PLA General Hospital. She received her MD degree in Chinese Military Post-graduate Medical School in 2008. Her clinical work focuses on vascular-targe-ted PDT for port wine stains and anti-tumor PDT, besides the common high power laser treatment and low level laser treatment. Her research focuses on the basic and clinical study of photodynamic therapy, such as the exploitation of new monitoring techniques and dosage optimization for vascular-targeted PDT. She is a member of Youth Committee in the Society of Laser Medicine of Chinese Medical Association.

Yueqing Gu, Professor of Biomedical Engineering, Dean of Engineering School in China Pharmaceutical University. She received his Master and PhD from Nanjing University of Aeronautics and Astronautics in 1989 and 1997, respectively. She then did her postdoctoral and research assistant professor in the University of Pennsyl-vania and University of Texas at Arlington/SW medical center from 1999 to 2004. Currently, she serves as members or executive members of academic councils. Her research is focused on the fluorescence probe and targeted prodrug for tumor diag-nosis and therapy.

Gang Liu is a professor at Xiamen University in China. He received his MD degree from North Sichuan Medical College (China) in 2002 and PhD degree from Sichuan University (China) in 2009. Subsequently, He focused his training on nanomedicine and molecular imaging at the National Institutes of Health (NIH) (2009-2011). In 2012, Dr. Liu joined the Center for Molecular Imaging and Translational Medicine (CMITM), Xiamen University. He is now working in the field of Biomedical Enginee-ring to develop various bio-inspired nanomaterials for cancer theranostic. His scien-tific work has been published as 100 papers in prestigious journals (Adv. Mater., Nat.

17


Commun., PNAS, etc.), 8 invited book chapter, and 12 patents. Now he is serving as editorial board members for several journals including Am J Nucl Med Mol Imaging and Quant Imaging Med Surg.

Xiaolong Liu is a Professor in Nanomedicine and the director of Liver Disease Re-search Institute at Mengchao Hepatobiliary Hospital of Fujian Medical University, a Professor in Biomedical engineering at Fujian Institute of Research on Matter of CAS, Fuzhou, China. He received his Ph.D. degree in Biophysics from Xi’an Jiaotong University in 2008. During his Ph.D. training, he has studied as a “Joint Ph.D.” in Brown University (USA); afterwards, he has worked as a Postdoc in Brown University (USA) and University of Basel (Switzerland) from May 2008 to Oct 2010; then he has worked as a Research Associate at University of Basel (Switzerland) from Nov 2010 to July 2013. His current research is focusing on biophotonics and nanomedicine for cancer diagnosis and therapy. He has published more than 40 scientific papers in the world recognized academic journals. He currently is also the adjunct Professor of Xi’an Jiaotong University, Fuzhou University. He has received the “Alexander von Humboldt fellowship” in 2008, and the “Young Scientist Award” of Japanese Cancer Association in 2015.

Pengfei Wang is a professor in Technical Institute of Physics and Chemistry, Chinese Academy of Sciences (TIPC, ACS). He received PhD. degree in 1993 from Institute of Photographic Chemistry of CAS, P.R. China. He then worked at Institute of Pho-tographic Chemistry of CAS (Technical Institute of Physics and Chemistry of CAS) as Assistant Professor and worked as a full Professor in 1997. From 1994, he worked in Paris as a visiting researcher of CNRS of France, National Institute of Materials and Chemical Research (NIMC) in Japan as a COE (Center Of Excellence) fellow, and COSDAF in City University of Hong Kong as a senior research fellow. He joined TIPC in 2005 as a professor. His current research interests include organic/inorganic luminescent materials for biosensors, bioimaging, and disease theranostic. He has authored or co-authored more than 150 peer-reviewed articles, and is named in 50 patents.

Guangjun Nie is a respected scientist of nanobiology and nanomedicine. He has a long standing interest in cancer biology and blood pathophysiology. Currently, his team is working toward design of bio-inspired materials to overcome the current bar-riers in tumor therapy and imaging. In particular, his group is working toward con-trolling the chemical properties of multifunctional nanoparticles in order to allow specific targeting and regulation of tumor cells and their microenvironment. He has been honored as CAS 100 Talents Scientist, Chief Scientist of National Basic Rese-arch Programs, Ministry of Science and Technology of China, and National Distin-

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中德科学中心

guished Young Scientists of National Natural Science Foundation (NSFC). He has an MBA and is currently the director of Science and Technology Department at NCNST.

Yanchun Wei is a doctor of Biomedical Photonics and associate professor at the Col-lege of Biophotonics South China Normal University, Guangzhou, China. He received his Ph.D degree in MOE Key Laboratory of Laser Life Science＆Institute of Laser Life Science, College of Biophotonics South China Normal University in 2012. He works as a senior fellow in the College of Biophotonics since 2007. His research focuses on the construction of biophotonics materials, especially the nano-based photosen-sitizers for enhanced photodynamic therapy and tumor imaging. He has published more than forty articles in his research fields.

Zhenxi Zhang is a professor of Biomedical Photonics and the director of Institute of Biomedical Analytical Technology and Instrumentation, School of Life Science and Technology, Xi‘an Jiaotong University, China. He received his PhD degree in Biome-dical Engineering and Instrumentation at Xi’an Jiaotong University in 1990. From 1991-1993, he made his postdoctoral research at University of Science and Technolo-gy of China. Since 1993, he has been as the associate professor of Biophotonics and finished his habilitation and became a full professor in 1998 at Xi’an Jiaotong Univer-sity. He has been the assistant dean of School of Life Science and Technology at Xi’an Jiaotong University from 2000 to 2006. Since 1976, he had done his research in se-veral Germany Universities including University of Stuttgart, the GSF-National Rese-arch Center for Environment and Health (Muenich), Robert Roessle Cancer Clinic of the Virchow University Clinic of the Humboldt University in Berlin, Wilhelmshaven University of Applied Sciences and Lübeck University of Applied Sciences. Currently, his interests are mainly in biomedical optics, optical biophysics, biomedical optical imaging and spectral analysis method.He has authored more than 200 publications and received more than 10 patents. He is the editorial members of Acta Laser Biology, Chinese Journal of Lasers and Frontiers of Optoelectronics.

Jianzhang Zhao is a professor at State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian. P. R. China. He received his PhD degree in Organic Chemistry from Jilin University in 2000. He has been the New Century Excellent Talents in Ministry of Education of China since 2008. After postdoctoral research at Pohang University of Science and Technology (South Korea), the Max Planck Research Unit for Enzymology of Protein Folding (Germany) and the University of Bath (UK) from 2000 to 2005, he returned to China to take his current position. His research interests include synthetic chemistry, photochemistry, photophysics and computational chemistry. Prof. Zhao has 3 patents, and he has pu-blished more than 200 papers on peer-reviewed journals.

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Dan Zhu is the Distinguished Professor of Huazhong University of Science and Technology (HUST); Deputy-director of Division of Biomedical Photonics,Wuhan National Laboratory for Optoelectronics; Vice-head of Department of Biomedical En-gineering, HUST; and the Secretary General of Biomedical Photonics Committee of Chinese Optical Society. She organized more than ten international or domestic con-ference during the past years. She is member of Editorial Board of Journal of Innova-tive Optical Health Sciences (JIOHS), Frontier of Optoelectronics, and Guest Editor of spcial issue of JIOHS, and Laser & photonics in Medicine. Her research interests inclued tissue optical imaging theory and methods; Biomedical spectroscopy and imaging; Optical clearing of tissue; Mechanism of Laser-Tissue Interaction. During the past years, she has developed innovative optical clearing methods for in vivo skin and kull. She has authored more than 100 papers (including 2 invited reviewer) and more than 20 invited talks on internal or international conference.

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中德科学中心

International Participants

Alexander Greer is a professor of chemistry at the City University of New York, Broo-klyn College since 1999. He is also a member of the faculty at the CUNY Graduate Center. He is a co-chair of the human rights group Committee of Concerned Scien-tists and an Associate Editor of Photochemistry and Photobiology. He is also a co-chair of the AAAS Science and Human Rights Coalition, Welfare of Scientists Group.He studies in the field of oxygen chemistry, reactive oxygen species, and sensitizer drug delivery but also embraces multiple technologies, even engineering.Research is focused on basic and applied photochemistry as being mutually supportive of each other. He has published in journals, with over 65 published papers and ~100 abs-tracts, contributed chapters to 3 books and is co-editor of one book.

Mauricio S. Baptista graduated in Pharmacy and Biochemistry, University of São Pau-lo in 1990, obtained a Master in Biological Sciences (Biochemistry) at the University of São Paulo in 1992 and a Ph.D. in Chemistry at Marquette University, USA in 1996. He was a post-doctorate fellow at UW-Madison School of Pharmacy, USA in 1997 and was a visiting professor at the Université Joseph Fourier (Grenoble-France) in 2006. Has been a faculty in the Department of Biochemistry, University of Sao Paulo since 1998, where he is currently full professor of Biochemistry, working mainly in the following subjects: photochemistry/photobiology, membranes and interfaces, photo-dynamic therapy, redox processes, mechanisms of cell death. Has published over 130 papers in international journals and has more than 3500 citations (h=33). Prof. Bap-tista has been working in the internalization process of the University of São Paulo since 2006 and became Associate Dean of international affairs in 2014.

Mathias O. Senge, graduated as Diplom-Chemiker from the Philipps Universität Marburg in 1986. After a PhD thesis in plant biochemistry with Prof. Horst Senger in Marburg (1989) and a postdoctoral fellowship with Prof. Kevin M. Smith at UC Da-vis, he received his habilitation in Organic Chemistry in 1996 at the Freie Universität Berlin. Next he was a Heisenberg fellow at the Freie Universität Berlin and UC Davis and held visiting professorships at Greifswald and Potsdam. In 2002 he was appoin-ted Professor of Organic Chemistry at the Universität Potsdam and since 2005 holds the Chair of Organic Chemistry at Trinity College Dublin. He has supervised more than 50 postgraduate students and post-doctoral fellows, published over 300 scienti-fic papers and given more than 150 invited lectures. His main interests are synthetic organic chemistry, the (bio)chemistry of tetrapyrroles, photochemistry, -biology and -medicine, structural chemistry, and history of science.

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Contact Information – German Participants

Name Institutional Affiliation Telefon and E-Mail

Beate RöderHumboldt-Universität zu Berlin, Institut für Physik

T:+49 30 [email protected]

Volkhard MayHumboldt-Universität zu Berlin, Institut für Physik

T.:+49 30 [email protected]

Steffen HackbarthHumboldt-Universität zu Berlin, Institut für Physik


Annegret PreußHumboldt-Universität zu Berlin, Institut für Physik


Wolfgang BäumlerKlinik und Poliklinik für Der-matologie, Universität Regens-burg

T:+49 941 9449607F: +49 941 [email protected]

Tim Maisch

Antimicrobial PDT and Cold Plasma,Klinik und Poliklinik für Dermatologie, Universität Regensburg

T: +49 941-944 [email protected]

Hans-Peter BerlienEv. Elisabeth-Klinik, Lasermedi-zin

T: +49 30 [email protected]

Jürgen Lademann

Charité – Universitätsmedizin Berlin, Klinik für Dermatologie, Venerologie und Allergologie, Bereich Hautphysiologie

T: +49 30 450 [email protected]

Martina Meinke

Charité – Universitätsmedizin Berlin, Klinik für Dermatologie, Venerologie und Allergologie, Bereich Hautphysiologie

T: +49 30 450 518 [email protected]

Ronald Sroka

Laser-Forschungslabor / LI-FE-Zentrum, Klinikum der Universität München, Campus Großhadern

T: [email protected]

Adrian Rühm


T: +49 89 4400 74882F: +49 4400 74864

Herbert Stepp


T: +4989 [email protected]

Michael KöhlDivision Solar Thermal and Optics, Fraunhofer-Institut für Solare Energiesysteme ISE

T: +49 (761) [email protected]

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中德科学中心


Rüdiger Faust

Universität Kassel, FB10 Mathe-matik und Naturwissenschaften, Institut für Chemie, Chemie mesoskopischer Systeme


Georg DaeschleinDepartment of DermatologyUniversity of Greifswald


Angelika RückCore Facility für konfokale und Multiphotonen MikroskopieUniversität Ulm N24


Sviatlana KalininaCore Facility für konfokale und Multiphotonen MikroskopieUniversität Ulm N24


Thomas GenschInstitut für Komplexe Systeme 4, Zelluläre Biophysik

T:+49-2461-614216 [email protected]

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Buhong LiSchool of Photonics and Electronic En-gineering, Fujian Normal University

T: +86 591 8803 7959; [email protected]

Daxiang CuiShanghai jiaotong University/Institute of Nano-Biomedicine and Engineering

T: +8621 [email protected]

Zhihua DingCollege of Optical Science and Engi-nee-ring, Zhejiang University


Ying WangDepartment of Laser Medicine, Chinese PLA General Hospital


Yueqing GuSchool of Engineering, China Pharmaceuti-cal University


Gang LiuSchool of Public Health, Xiamen University


Xiaolong LiuMengchao Hepatobiliary Hospital of Fujian Medical University


Junle QuCollege of Optoelectronic Engineering, Shenzhen University


Pengfei WangTechnical Institute of Physics and Chemis-try of the Chinese Academy of Sciences


Guangjun NieNational Center for Nanoscience and Tech-nology, China


Yanchun Wei

MOE Key laboratory of Laser Life Scien-ce, College of Biophotonics, South China Normal University/ Jiangsu Key Laboratory for Interventional Medical Devices, Huaiyin Institute of Technology


Zhenxi ZhangSchool of Life Science and Technology, Xi’an Jiaotong University


Jianzhang ZhaoState Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology


Dan Zhu

Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong Uni-versity of Science and Technology (HUST)


Contact Information – Chinese Participants

24


中德科学中心

The City of Berlin

The oldest human traces in the area of later Berlin are dating to the 9th millennium BC. During neolithic times a large number of villages existed in the area. In the 6th century, the main settlements were todays Spandau and Köpenick. In the 12th cen-tury, the region came under German rule as part of the Margraviate of Brandenburg, founded by Albert the Bear in 1157. At the end of the 12th century, German merchants founded the first settlements in today’s city center, called Berlin around modern Ni-kolaiviertel and Cölln, on the island in the river Spree now known today as the Spre-einsel or Museum Island. Berlin is mentioned as a town for the first time in 1251 and the year 1237 was later taken as the year of founding.

Situated at the crossing of two important historic trade routes, Berlin became the capital of the Margraviate of Brandenburg (1417–1701), the Kingdom of Prussia (1701–1918), the German Empire (1871–1918), the Weimar Republic (1919–1933) and the Third Reich (1933–1945). Berlin in the 1920s was the third largest municipality in the world. By the end of World War II up to a third of Berlin had been destroyed and Greater Berlin was divided into four sectors by the Allies. On August 13, 1961 the GDR government started to build a wall, physically se-parating West Berlin from East Berlin. The fall of the Berlin wall in November 1989

and the subsequent unification of Germany marked a new beginning of the city triggering its transition to the multicultural world city in the he-art of Europe Berlin is today.

Berlin is a world city of culture, poli-tics, media and science. Its economy is based on high-tech firms and the service sector, encompassing a diver-se range of creative industries, rese-arch facilities, media corporations and convention venues. Significant Berlin Cathedral Church, Festival of Lights

Map of Berlin, 1688

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industries also include IT, pharmaceuticals, biomedical engineering, clean tech, biotechnology, construction and electronics. It’s important position as a capital over many decades is reflected by a number of historic sites like e.g. Charlottenburg Pala-ce, the Brandenburg gate and three major Cathedrals as well as the famous Pergamon Museum and the Museum of Natural History.

Modern Berlin is home to world renowned universities, orchestras, museums, enter-tainment venues and is host to many sporting events. Its urban setting has made it a sought-after location for international film productions. The city is well known for its festivals, diverse architecture, nightlife, contemporary arts and a high quality of living.

Humboldt-Universität zu BerlinIn 1810, Wilhelm von Humboldt’s idea of founding a new type of university became a reality. The combination of tea-ching and research, academic freedom and the compre-hensive education of students was not only a model for the Prussian university but for the world as well. Moreover, a new era for universities and academic research began.

“Something that is more important to me personally than anything else is the founding of a new university here in Berlin.” Wilhelm von Humboldt (1810)

The university has undergone many changes over the past 200 years. After an extraordinary process of restructuring and renewal after the po-litical changes in 1990, it drew in academics and scientists from both the East and West, Germany and abroad. In 2016, Humboldt-Universität zu Berlin was among the top five in the German Research Foundation research rankings, and it is in 41st place worldwide in the World Reputation Ranking and 3rd place in Germany.

The Original Modern UniversityThe ground-breaking ideas from 1810 remain relevant today. Wilhelm von Humboldt as well as his contemporaries promoted research independence, the integration of humanities and the natural sciences and the unity of teaching and research over 200 years ago.

Wilhelm von Humboldt

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中德科学中心

The university modelled on the ideas of the brothers Wilhelm and Alexander von Humboldt opened in 1810 and quickly developed into a lively place for discussion for respected scholars including the philosopher Hegel, the legal scholar von Savigny and the physician Hufeland.

After the founding of the German Empire in 1871, the Berlin alma mater became the largest and most prestigious university in Germany. Humboldt’s ideas spread across the world, and many universities were founded on the same principles. 29 Nobel Prize winners including Max Planck, Robert Koch, and Fritz Haber conducted rese-arch here. Otto von Bismarck, Heinrich Heine and Karl Marx were also enrolled as students at Humboldt-Universität.

In 1949, the university was named after the brothers Alexander and Wilhelm von Humboldt. Humboldt-Universität maintains academic partnerships with over 375 universities. Traditionally, it has close ties to North, Central, and Eastern Europe and cooperates with universities in the USA, Asia, Cuba and South Africa. The univer-sity has for years operated the largest program for the German Academic Exchange Service’s (DAAD) support of partnerships with the East, and with over 100 fellows is ranked at the top of German universities.

Student mobility is a major focus at the uni-versity; more than 800 students complete a part of their studies abroad, and about 1,200 international students study abroad at HU. Each year, about 800 researchers from all over the world spend time at Berlin’s oldest university. The International Scholar Ser-vice (ISS) helps doctoral students and rese-archers from abroad orient themselves ea-sily in the university and the city.

The “Friedrich-Wilhelms-Universität zu Berlin” in 1852.

Engraving by F. Hirschheim based on C. Würbs

Molecule Man, Spree

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Humboldt-Universität is expanding collaboration with selected universities throug-hout the world at the levels of research, teaching and governance. These HU profile partners represent leading institutions in their respective regions and include the University of Sao Paulo, the National University of Singapore and Princeton Univer-sity.

The Collections and the Humboldt ForumHumboldt-Universität has a treasure trove of objects from over 300 years of teaching and research – there are over 30 million objects from the humanities, social sciences and natural science. They are cared for, maintained at the university’s institutes, fa-culties and libraries, and used in teaching, research and exhibitions. The Helmholtz Centre of Cultural Technology’s databank and scientific cabinet includes current and former collections from Humboldt-Universität. It focusses on zoological objects, me-dical history, images of scholars, and other images as well as recordings from the sound archive. Since 2004, the University Collections in Germany has been mana-ged at the Helmholtz Centre. Additional collections historically and institutionally connected with Humboldt-Universität can be found in the Berlin Museum of Medical History and other institutions at the Charité – Universitätsmedizin Berlin as well as the Museum of Natural History – Leibniz Institute for Research on Evolution and Bio-diversity at Humboldt-Universität zu Berlin.

What‘s where?

T Tram stop Köllnischer PlatzH Hotel am Schloss Köpenick Berlin by Golden Tulip, Grünauer Straße 17-21

Take Tram #61 or #63 (direction: Karl-Ziegler-Straße) to Tram stop Ma-gnusstraße (see map on opposite page).

© OpenStreetMap contributors, www.openstreetmap.org/copyright

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