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Copyright © 2017 Nutra Active Pte Ltd

All rights reserved.

Published by Derek Evans.

No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or

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CONTENTS ........................................................................................................................................................... 3

INTRODUCTION ................................................................................................................................................... 4

CHAPTER 1 What is Leptin? ................................................................................................................................ 5

CHAPTER 2 The (Almost) Inescapable Cycle ....................................................................................................... 7

CHAPTER 3 Signs of Leptin Resistance ............................................................................................................. 10

CHAPTER 4 The Solutions ................................................................................................................................. 13

CONCLUSION ..................................................................................................................................................... 15

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We’ve got a secret to share with you, and it’s one that might alter your perception of

weight loss entirely.

New evidence that challenges what we thought we knew about weight loss has recently

surfaced – it may be more than just simple “calories in” versus “calories out.”

It’s long been known that people who struggle with obesity usually struggle with hormonal

problems as well, since a lot of hormones are connected to body fat percentage. Recently it

has come to light that one hormone might have more to do with it than others.

Researchers have found evidence of something that is quickly becoming known as the

Master Hormone. Its name is leptin, and it may hold the key to permanent weight loss. It is

what tells your body to “stop eating”, and its name comes from the Greek word leptos,

which literally means thin.

It is one of the most important hormones in the body, and controls everything from hunger

to energy expenditure. If functioning correctly, you’ll have better metabolic performance,

cognitive ability, co-ordination and even more stable emotions and mood.

However, if it is not functioning properly, it can lead to severe obesity. Your entire body will

feel out of whack, and you’ll find yourself eating more and more. This is called leptin

resistance, and it is one of the leading causes of obesity in the world today.

If you suffer from it, you can find yourself eating and eating, unable to feel full. It can take a

serious toll on your health and mental state. Understanding leptin can totally change your

life around and improve your health in a variety of ways, including making losing weight

easier. It’s not just about losing weight either. As many of us know, keeping it off is probably

the hardest part.

But leptin is the key to that as well. In this report, you will learn all about leptin, what leptin

resistance is and how you can solve it in a natural and safe way.

The master hormone will help you deal with that stubborn belly once and for all.

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Before we learn how to control leptin, we have to first understand what it is. Knowing how

it works makes all the difference when it comes to fighting leptin resistance.

Leptin is the hormone that is closely related to regulating a lot of things, including energy

intake and output, appetite, metabolism, and hunger. When it comes to hunger, it is the

most important hormone there is, as it dictates whether we are hungry or full. Thus, it is

also known as the “satiety hormone” or the “starvation hormone”.

It primarily communicates with the brain, namely the

hypothalamus region. This is the region of the brain

that mostly governs motivational behavior, and is

what tells the body when we are hungry or thirsty.

It also plays a part in connecting the endocrine and

nervous systems. When there are high levels of leptin

in our bodies, it stimulates receptors in the

hypothalamus, which then releases appetite

suppressing-hormones, which tell us that we are full

and makes us stop eating. On the other hand, low

levels tell the brain that we’re hungry and need food.

The funny thing is that this hormone is actually produced by our fat cells, otherwise known

as our adipose tissue. This means that it is proportional to your body fat percentage, so the

higher the percentage, the more leptin you have.

This might seem odd, since we just said that more leptin should lead to less appetite, but it

makes sense when you consider the prevalence of yo-yo diets out there. When you lose a

lot of weight too fast, your leptin levels drop dramatically, making you a lot hungrier. Your

metabolism drops as well. This usually causes you to eat more as your appetite increases,

and before you know it, you’ve gained back the weight.

This is why crash diets are so prone to failure, as your leptin levels adjust so that you just

cannot eat less. The diet messes up your body’s metabolism and appetite levels, causing a

lot of people to put the weight back on, and then some. This becomes a cycle that is hard to

break and some just give up entirely.

Your leptin levels are more sensitive to starvation than they are to overeating.

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This means that cutting calories and burning fat leads to much lower levels, increasing your

appetite along with it. On the other hand, when you eat too much, your levels rise, but they

don’t skyrocket, so if you don’t pay close attention to what your body is telling you, it can

be very easy to overeat.

Since it was discovered how big a role leptin plays in how full you feel and your appetite

levels, researchers have been hard at work trying to unlock its secrets. It could potentially

be one of the most important discoveries in weight loss of the last few years, and from what

scientists have found, that is looking more and more likely.

What they did was take mice and increase the leptin in their brains. This caused them to

exercise more, and proved how it is interwoven with the way our bodies control our activity

levels, ration out energy and regulate our metabolism. Basically, leptin plays a big part in

the energy balance within us – such as immediately making us hungrier when we fast.

It also plays a part in preventing diabetes, as it can

reduce the lipids in your body’s tissue – which can

lead to the dreaded insulin resistance. Even more

intriguing is the fact that it even helps us decide what

kinds of foods we find appetizing. It does so by

affecting key regions in the brain, leading to

diminished perception of food rewards.

We realize all of this makes it seem like the solution to weight loss is to give people more

leptin. It makes sense after what we’ve learned doesn’t it? Increase leptin to reduce

appetite and you’re well on your way to weight loss!

Unfortunately, this isn’t exactly the case. In our next chapter, we’re going to learn about the

dreaded condition that affects people all the around the world, and it’s something not many

of them are even aware of.

It’s fast becoming an epidemic, but by understanding it, you can take your first steps

towards correcting it.

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It should be simple. Increase our leptin levels, feel fuller, be more energetic, and lose more

weight. However, like many things to do with weight loss and the body, it’s not.

There’s a sneaky condition that can make it so that leptin doesn’t work on us anymore –

leptin resistance.

This is one of the biggest causes of obesity in the world today, and there’s a good chance

that if you’re overweight, you are suffering from it. It all comes about because our bodies

are trying to adjust for the levels that we do have.

Researchers set up clinical trials where patients were given leptin to see if they would lose

any weight. They didn’t, mostly because the subject’s bodies kept trying to adjust the base

line levels.

You see, the more leptin there is in your system, such as in overweight or obese people, the

less effective it becomes. Your brain loses sensitivity to the hormone, leading to leptin

resistance. In mice, it was found that all it took was 3 days of overeating to reach this state.

In this state, what happens is that you gain a lot of fat, and subsequently, a lot of leptin. But

your brain just isn’t listening to the signals it’s getting, so your appetite doesn’t drop, your

metabolism doesn’t increase, and in some cases, your brain can’t detect the leptin at all.

If this happens, you will constantly be told by your own brain that you’re starving, so you’ll

constantly be hungry.

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This leads us to the title of this chapter – The (Almost) Inescapable Cycle. It goes like this:

1. You eat more, and gain more fat

2. This leads to more leptin

3. The higher amount of fat in the body disrupts the leptin signals

4. Your brain can’t ‘hear’ the leptin, so you’re hungry

5. You eat more and put on more weight

6. The cycle repeats

It can be likened to insulin resistance. This occurs when there’s too much insulin being

produced, but the body just isn’t responding to it. It is a precursor to diabetes, and is usually

brought on by a high sugar and simple carbohydrate diet.

What’s interesting about this is that both types of resistance seem to occur mainly in obese

people. Men (who tend to have more belly fat) usually have higher insulin levels, and

women (who tend to store fat under the skin) have higher levels of leptin.

There’s another interesting fact about leptin resistance. High levels of fructose seem to

cause it. This is the sugar that is found in fruits, and is also called fruit sugar for that reason.

This sugar interferes with leptin’s ability to cross the barrier from the blood into the brain.

When this happens, it’s almost as if there is a wall between leptin and the place it needs to

get to – the hypothalamus.

If it doesn’t get there, your brain won’t know that you have adequate levels, and will make

you feel hungry. This leads us to one of the theories about how leptin resistance works. The

prevailing theory is that it can’t reach the hypothalamus because the proteins needed to get

it across the barrier don’t work, or just aren’t there.

So, essentially, leptin resistance causes the brain to actively defend the amount of fat you

have in your body, even if it is way too high. This means that if you lose the weight, your

brain wants you to get it back on, so you are compelled to do so.

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Your thyroid and leptin are connected, and both play a part in leptin resistance and weight

gain. Your thyroid is what produces the hormones that go through the entire body, playing

a part in your metabolism, as well as your growth and development.

Your leptin levels affect your thyroid’s hormone production.

As we said before, leptin has a big part

to play in your energy expenditure.

When you can’t utilize your leptin,

leptin resistance occurs and you end

up getting hungry.

This also affects your thyroid, as the

leptin effectively tells the thyroid to

release low energy hormones to

conserve energy to prevent starvation.

Your metabolism is also slowed so that you can get through this perceived starvation

period, so that you burn less calories each day. This makes weight loss next to impossible,

while weight gain becomes a whole lot easier.

Your energy levels take a hit as well. A low thyroid equals less energy for your cells, so you

get lethargic, again promoting weight gain.

If you’ve ever been on a crash diet before, then all of this will be familiar. Weight loss is

always easier in the beginning, and the weight will start to drop off easily. However,

gradually the obstacles start popping up. Hunger, cravings, and fatigue set in.

Before you know it, you’ve given up completely, and have piled the weight back on, and in

many cases, added some extra to it as well. This can be incredibly discouraging, and it taxes

you both mentally and physically. But th ere is hope.

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So now that you know all about leptin and leptin resistance, it’s time to figure out for

certain if you’re indeed suffering from it.

The bad news is that millions of people all over the world do have this condition, and it can

lead to serious health conditions.

The good news is that there is a solution if you are leptin resistant, but the first step is

discovering whether you are or not, so let’s get to it.

This is by far the easiest way to tell whether or not you’re leptin resistant, so get on that

scale. If you’re more than 15 pounds overweight with a high amount of belly fat, it’s almost

a given that you have leptin resistance.

As we said before, weight gain is a good indicator that your brain can’t interpret the signals

leptin is sending it.

Finding it incredibly hard to lose weight is another sign that you should look out for. So,

don’t be discouraged if you feel like you’ve tried everything; the solution might be to

resolve your leptin issues first.

This doesn’t just apply to overweight people either. In fact, if you’re more than 10 pounds

underweight, your brain might not be able to read the leptin signals correctly.

So, if your weight falls on either side of the unhealthy range, it is a good indicator that you

might be leptin resistant.

If you’re constantly craving something to eat, or just can’t stop yourself from snacking all

the time, leptin resistance might be to blame. It happens to a lot of people who try to diet.

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They try and make their main meals as healthy as possible, but snacks between meals then

become a problem. Junk food cravings can sometimes take over, and before they know it

they’ve consumed a high-calorie, high-fat bag of chips.

If you can’t go between meals without desperately needing a snack, there’s another

indicator for you.

A lot of people tend to make this mistake. They figure that if cutting 300 to 500 calories

helps you lose weight, then cutting even more will make it a faster process.

This is a bad idea. Drastically cutting your calorie

intake has a host of negative consequences,

including muscle degradation, and it can cause you

to become more resistant to leptin.

If you go on an extreme cut, your body will try and

hold onto stored fat, as it thinks that you’re starving

and tries to compensate to keep you alive.

This makes it extra hard to lose weight.

Crash diets are the worst ways to lose weight, and if you’re considering going on one, you

should reconsider. If you’re already crash dieting, now is the time to stop. You need a plan

that is sustainable over the long-term. Fitness is a marathon, not a race.

It’s become all too common in today’s world.

We are all sleep deprived and stressed out, and

it is taking a toll on us. Most people don’t know

just bad this toll can be.

High stress and little sleep makes your cortisol

(stress hormone) levels skyrocket. Which leads

to more stress and less sleep.

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Which leads to more cortisol. See how it’s easy to get trapped in a cycle?

All of this negatively affects your health, and contributes to leptin resistance. If you don’t

correct this issue, you’ll end up gaining weight, getting chronic inflammation and put

yourself at risk of heart disease.

Everything you put in your mouth affects your

body in some way, and it even plays a part in

how well your body can process everything

you eat.

The typical modern diet is really bad for you.

Sugar, simple carbs, chemicals and

preservatives are in more abundance than

nutrients, and this is harming your body.

Not only does it put you at risk of a whole range of diseases and conditions, but it affects

your leptin resistance as well. Things like soda and candy will give you a temporary energy

shot, but they’re processed so fast by the body that you just end up hungry sooner rather

than later.

They also give you a surge of leptin each time you eat them. And then those levels drop

right after as there is nothing nutritious in your foods.

This constant up and down affects your body’s ability to process it, which leads to your

brain thinking that you are always hungry.

In response, you eat more, and pack on the pounds.

If you’re suffering from one – or even all – of the above symptoms, there is a very good

chance that you have leptin resistance. Don’t panic! With a few simple tweaks, you can

solve it and get on the road to healthier, and happier, you.

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Fixing your leptin resistance is not that complicated. In fact, none of the following tips will

sound fancy or revolutionary, but trust us, if you stick with them, you’ll be able to fix this

issue and start shredding the fat in no time.

Keep in mind that these tips are mostly about changing your lifestyle. They’re not an

overnight fix. You’re going to have to stick with them to get the benefits.

This is not just for leptin resistance, but for an overall healthier you. By junk, we mean

overly processed, nutrient-lacking foods like fast food and fat-loaded snacks. You can have

them every now and then as a treat, but otherwise you need to focus on whole foods that

are nutrient dense.

Try to cut out sugar and fat as much as you can, though. One way is to slowly wean yourself

off it, eating less and less, eventually saving meals that contain high amounts of it for cheat

meals. Diets high in saturated fat and sugar promote inflammation in the hypothalamus,

which causes leptin resistance.

The slow-burn energy, fiber and nutrients in stuff like vegetables, protein and healthy fats

(avocados, olive oil, etc.), will help keep you full for longer, provide you with energy to go

through your day and help nourish your body effectively. You’ll look, and most importantly,

feel better on a diet of whole foods.

This is very important, not only for leptin resistance, but weight loss overall. You need to

ensure that protein accounts for 15% to 30% of your daily caloric intake, as this will result in

significant weight loss and increase leptin sensitivity.

More protein will also compensate for the increase in appetite you’ll get from cutting out

the carbs. It’s been proven that low-carb diets are really good for weight loss, and can also

lower triglycerides.

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These are essential for the health of both your body and your brain. They are fantastic

inflammation fighters, and can even help ease symptoms of depression, Alzheimer’s and

other such mental issues. Some of the best sources include salmon, walnuts, and ground

flax seeds.

Overeating is one of the main causes of leptin resistance, making it harder to lose weight

and get fit. So, one of the solutions is to start eating less, and make sure each meal is as

nutrient-dense as possible.

This is where whole foods come in. Let’s use broccoli as an example. 100 grams of it has

only 34 calories, but a ton of fiber. So, you can munch on a whole plateful, fill yourself up

and not be guilty.

If you can’t resist the urge to snack, make sure to only eat small portions of healthy stuff,

like nuts or fruit and yogurt. They’re relatively low in calories and have high nutrient

content, so they’ll benefit your health and your belly.

This is one of those things that’s going to benefit you in so many ways that we can’t stress it

enough. It’s not only good for burning calories, but also for heart health, adding muscle,

preventing pain, and most important, improving leptin sensitivity.

Sticking with it is important as well, as an active lifestyle can lead to better health, and

result in you aging more gracefully.

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Leptin resistance is one of the leading causes of obesity in today’s world. A combination of

stress, a lack of time to exercise and a host of other factors have come together in an

almost perfect storm to create it, and if you don’t do something about it, you could end up

with a ton of health problems very early on.

Thankfully, reversing it is an uncomplicated process. All you have to do is follow the tips we

provided in the previous chapter. It all boils down to cleaning up your diet and exercising

more. Not only will this help you improve leptin sensitivity, but it will also help you lose

weight, reduce stress and inflammation and improve your overall quality of life.

Just because the process is not complicated, however, does not mean it is easy. We realize

that changing your lifestyle is a difficult thing to do, and leptin resistance will make you

want to eat more and give up on it entirely. It’s going to be difficult, but not impossible.

Start by making small adjustments to your eating habits. Include more whole foods in your

day to day meals, and slowly cut out the junk. Start by taking short walks every day, and

gradually move up to more strenuous activities like jogging or running. Even a small step

forward is a step in the right direction, so every little bit helps. Remember that.

Keep in mind that adjusting your diet to include more whole foods does not mean going on

a diet. The term ‘diet’ has gotten a bad reputation recently, with all the fad diets out there.

If you think you’re going on one, you can end up sabotaging yourself, as your brain

associates the word with restriction and difficulty.

So, don’t think of it as such. This is a lifestyle change, one that will benefit you in the long

term and have you looking and feeling better in no time at all. Consistency is key, and once

you’ve done it for long enough, it will become a habit that is easy to maintain.

What are you waiting for? It’s time to start reversing your leptin resistance, and getting on

the road to becoming a happier and healthier you.