UCSF Center for AIDS Prevention Studies (CAPS)

Division of Prevention ScienceDepartment of Medicine

Marguerita Lightfoot, PhD Director

Susan Kegeles, PhD Co-Director

Mallory Johnson, PhD Co-Director

CAPS

• Newly relocated to Mission Hall @ Mission

Bay, 3rd floor

• Weekly Town Halls (Tuesdays 12 – 1 pm)

• Caps.ucsf.edu

Mission

• CAPS has three long-term goals:

– preventing new HIV infections,

– developing social/behavioral approaches to improve

health outcomes among HIV-infected people, and

– reducing disparities.

• UCSF is the largest recipient of NIH funding of Departments of Medicine.

• The Division of Prevention Science is the largest recipient of NIH funding of the 16 Divisions in the Department.

• Prevention Science faculty are 4% of the Department of Medicine but account for 16% of NIH funding.

Division of Prevention Science Faculty FY 14

• Professor (11)– Stephen F. Morin, PhD, Emeritus– Susan M. Kegeles, PhD– Kyung-Hee Choi, PhD, MPH– Marguerita Lightfoot, PhD– William J. Woods, PhD– Diane Binson, PhD, Emeritus– Edwin Charlebois, PhD, MPH– Mallory O. Johnson, PhD– Maria Ekstrand, PhD– Torsten Neilands, PhD– Judy Auerbach, PhD

• Associate Professor (6)– Janet Myers, PhD, MPH– Lynae Darbes, PhD– Tim Lane, PhD, MPH– Emily Arnold, PhD, MPH– Wayne Steward, PhD, MPH– Hong-Ha Truong, PhD, MS, MPH

• Assistant Professor (8)– Jae Sevelius, PhD– Nicolas M. Sheon, PhD– Starley Shade, PhD– Greg Rebchook, PhD– Sheri Lippman, PhD, MPH– Parya Saberi, Pharm.D.– Mi-Suk Kang Dufour, PhD, MPH– Sarah Woolf-King, PhD

Center Grant• The Center for AIDS Prevention Studies

(CAPS) is a P30 grant from NIMH will be in year 4 of 5 years (FY 15) – 9/1/12–6/30/16.

• Funding for the center is $1.6 million, a reduction from prior years.

• The CAPS center grant covers 9% of the Division’s core operating expenses.

Grant Awards by Fiscal YearDirect Indirect Total

FY10Division totals 15,065,279 2,364,283 17,429,562

FY11Division totals 16,455,064 2,388,995 18,844,059

FY12Division totals 17,424,809 1,987,861 19,412,670

Center for AIDS Prevention Studies• In 2013, CAPS provided services to over 100 investigators

and trainees conducting HIV prevention research.

• This included service to over 100 research and training grants.

• In 2013, CAPS investigators published over 150 papers in peer reviewed journals.

• CAPS remains the largest university-based group of social, behavioral, policy and prevention scientists responding to HIV in the world. (Don’t forget about us!)

CAPS RESEARCH• International• Policy research• Methods• Translational and implementation science • Gay men, MSM and MSMW• HIV+ • Adherence to medications; linkage to care; engagement in care• Disparities in HIV-related outcomes• Transgender persons• Youth & young adults

Also:

Technical assistance and capacity building

Traineeships

CAPS Research

Susan M. Kegeles, PhD - Professor CAPS Co-Director & TAPS (Postdoc) DirectorPopulations: MSM – (young, black, Latino, South African, Peruvian) & MSMW

• Community-Level HIV Prevention for Young Black MSM

• Combination Prevention & Community Mobilization for Continuum of Care among HIV+ young black MSM

• Translating Research into Practice at Community-Based Organizations

Marguerita Lightfoot, PhD - Professor CAPS Director (Adolescents & technology)Populations: Adolescents, youth, community based participatory research• Computer-Based vs Interpersonal HIV Preventive Intervention for At-Risk Youth• HIV Prevention Research in Minority Communities• Infrastructure For Community-Linked Research• Technology to connect at-risk youth to testing

CAPS Research

Mallory Johnson, PhD – ProfessorCAPS Co-Director Populations: HIV+ persons, couples, mentoringArea: US, South Africa• DUO Project: Relationship factors and HIV treatment adherence•The PATH Project: A Randomized Controlled Trial Preparing Patients to Start Antiretroviral Therapy

Mi-Suk Kang-Dufour, PhD, MPH - Assistant Professor Populations: MSM, incarcerated adults, African American •Linkages to care among HIV+ persons coming out of prison •HIV testing, linkage to care and PrEP among MSM of color

CAPS Research

Emily Arnold, PhD, MPH - Associate ProfessorPopulations: MSM, African American, faith communities (Black gay youth, House

Ball community)

• BRUTHAS Randomized Control Study

• The Ballroom Community Project: Social Networks and Social Support

among High Risk African American Men

• Policy related research in California

Diane Binson, PhD – Professor Emeritus Populations: MSM, Latinos, incarcerated adults, heterosexual (Bathhouse and survey methods)• Improving Self-Reports About High Risk Sexual Behavior• HIV Risk among Male Parolees and their Female Partners• Exploring the Core of High Risk Networks• Multi-level Prevention in Culture & Context with Latino Men• SPSN for Seropositive Young Men of Color• Collaborative HIV Prevention Research in Minority Communities

CAPS ResearchEdwin Charlebois, PhD, MPH - ProfessorPopulations: Gay men, PLWH

Area: US, Uganda

• Structural Alcohol/HIV Risk Intervention in Gay Bar Patron

• Project Promote: Novel Strategies to Prevent Malaria and Improve HIV Outcomes in Africa – Data and Statistics Core

• Family-Based HIV VCT for Patients at Risk for TB

• Modeling the Impact of Ryan White Care Act Severity of Need Indices

Kyung-Hee Choi, PhD, MPH - Professor Populations: MSMArea: US, China• Social/Sexual Networks & HIV Risk: Men of Color• CHATS: Developing a Network Intervention to Promote Women’s Health• Developing a Network-based HIV Prevention Intervention for MSM in China

CAPS ResearchLynae Darbes, PhD - Associate ProfessorPopulations: Gay and heterosexual couples

Area: South Africa

• Couples in Context: Piloting a Couples-Based Intervention in South Africa

• Couples-based HIV prevention in South Africa

• Developing a comprehensive couples-based intervention in South Africa

Maria Ekstrand, PhD - Professor Populations: MSM, women, sex workers, migrant workers, HIV+ personsArea: India• Examining ART adherence issues in Bangalore, India • AIDS stigma and gender: Health consequences in urban India • Contexts and correlates of health behaviors in South India

CAPS Research

Tim Lane, PhD, MPH - Associate Professor Populations: MSM, healthcare providers•HIV Prevention among Township MSM in South Africa • MSM Community Mobilization for HIV Research • Surveillance/epidemiological investigations of groups at risk in Africa: sex workers, MSM, other high risk groups

Sheri Lippman, PhD, MPH - Assistant ProfessorPopulations: Heterosexual women, MSM of color•Effects of cash transfer and community mobilization in young South African women•Understanding Community Mobilization for HIV Prevention in the AfricanContext•Assessing the feasibility of conducting a randomized community trial of theEncontros intervention model among sex workers in Brazil

CAPS ResearchJanet Myers, PhD, MPH - Associate ProfessorPopulations: healthcare providers, HIV+ persons, NGOs

Area: US, Ukraine

• Evaluation of patient perspectives on routing HIV screening in health care settings

• Strengthening capacity to deliver HIV research counseling and testing in international biomedical prevention and treatment trials

• Implementation science/HRSA SPNS projects

Tor Neilands - ProfessorDirector, Methods Core• Quantitative data analysis methods and survey scale development

• Fostering and conducting behavioral HIV/AIDS-prevention research in racial and ethnicity minority populations and communities

• Advanced quantitative methodological, statistical, and data analytic support for epidemiological and behavioral HIV prevention research efforts.

CAPS ResearchGreg Rebchook, PhD - Assistant ProfessorCo-Director, Technology and Information Exchange Core (TIE

Core) Populations: MSM, African American, Transwomen• Capacity Building Assistance (CBA) to Assist CBOs • Moving a Research-Based Intervention into Practice• HIV Prevention with sexual minorities, including black MSM, trans

• Implementation science, HRSA SPNS

Parya Saberi, PharmD, MAS - Assistant Professor• Technology-based Adaptive Treatment Strategies for Antiretroviral Adherence • Social Networking Technologies in Improving Treatment Engagement of Young

Black HIV+ Individuals• HIV and Aging

CAPS Research

Jae Sevelius, PhD - Assistant ProfessorPopulations: Transgender, HIV+ persons,

• Co-Principal Investigator, Center of Excellence on Transgender Health

• Sheroes / Sheros Plus Projects – An intervention to reduce risk behaviors among HIV-positive and negative transwomen.

• T-Sista – HIV Prevention for African American transwomen.

Starley Shade, PhD - Assistant ProfessorCo-Investigator Policy & Ethics Core & Methods CorePopulations: healthcare providers

• Application of Weighted Time-series to Address Bias in Evaluation of Clinic- and Community-level Research

• PI for a CDC cooperative agreement to provide technical assistance, capacity building and organizational development in Mozambique

• Implementation science, SPNS

CAPS ResearchNicholas Sheon, PhD - Associate Professor Co-Investigator: Methods Core – Qualitative ResearchPopulations: MSM, HIV+ persons

• Investigating Motivations for Participation in Anal Cancer Prevention Trials)

• A Structural Intervention to Improve HIV Test Counseling

• Using technology to streamline data collection and improve HIV test counseling

Wayne Steward, PhD, MPH - Associate ProfessorCo-Investigator: Policy & Ethics CorePopulations: gay men, HIV+ persons, policymakers, CBOs

• A formative study on the role of gender, ethnicity and sexual orientation in the provision of prevention counseling with HIV+ patients

• Severity of need: California health care financing and policy research initiative

• Implementation science (HRSA SPNS)

CAPS ResearchHong-Ha Truong, PhD, MS, MPH - Associate

Professor Populations: gay men

Area: Vietnam, Zimbabwe• International Travel Research to Inform Prevention (I-TRIP) • Monitoring Resistance During Rapid Expansion of Antiretroviral Therapy• Molecular epidemiology

Bill Woods, PhD - Professor Co-Investigator: Policy & Ethics CorePopulations: MSM/F, substance users (Bathhouses)• Vice Chair, UCSF IRB• Co-Investigator: CAPS Visiting Professor Program• Systems Linkage and Access to Care initiative (SLAC)

International Research Sites 2013• Philippines• Russia• St. Kitts and Nevis

• St. Vincent and the Grenadines

• South Africa• Tanzania• Thailand• Trinidad & Tobago• Uganda• Ukraine• Venezuela• Vietnam• Zimbabwe

• Antigua and Barbuda• Argentina• Barbados• Botswana• Brazil• Burkina Faso• Cambodia• Chile• China• Colombia• Croatia• Dominican Republic• Ecuador• Georgia• Guatemala• Haiti

• India• Indonesia• Iran• Japan• Kazakhstan• Kenya• Malawi• Morocco• Mexico• Morocco• Myanmar• Nepal• Namibia • Nepal• Nigeria• Peru

Thank You!