TY Yoon CV Short version with full publication recordsyoonlab.snu.ac.kr/TY Yoon_CV.pdf2014. 02...
Transcript of TY Yoon CV Short version with full publication recordsyoonlab.snu.ac.kr/TY Yoon_CV.pdf2014. 02...
TAE‐YOUNG YOON
Associate Professor
Department of Biological Sciences
Seoul National University
Seoul 08826, South Korea
E‐mail: [email protected]
RESEARCH INTEREST
Single‐Molecule Biophysics: My research group aims to understand molecular mechanisms of “the integral membrane proteins”, which have been largely shunted aside in spite of their biological and practical importance. My group employs an arsenal of single‐molecule techniques to observe both conformational changes and consequential function of the membrane proteins, which allows direct determination of their structure‐function relationship. We recently reported the disassembly mechanism of the SNARE complex by a proteasome system (20S complex), which provides insights into how AAA+ ATPases tightly couple their ATP hydrolysis and unfolding of protein substrates (JACS 2013 and Science 2015). In addition, my research group is pioneering an approach where we apply mechanical tension to the integral membrane proteins while observing their function, which allows determination of the energy landscape governing conformational changes of the membrane proteins (Nat. Comm. 2013, 2014 and Nat. Chem. Biol. 2015). This series of works
is being supported by the National Creative Research Initiative Program (창의적연구진흥과제, 단분자시스
템생물학 연구단).
Development of Tools for Precision Medicine: My research group is also interested in development of new single‐molecule imaging tools. We recently developed single‐molecule version of co‐immunoprecipitation (co‐IP) analysis (Nat. Comm. 2013, Nat. Prot. 2013). In molecular biology, the co‐IP analysis has been the gold standard of determining protein‐protein interactions (PPIs) for several decades. By adopting single‐molecule fluorescence microscopy as the detection method (instead of SDS PAGE‐gel and western blotting), we have improved the sensitivity and time‐resolution of the co‐IP analysis by five orders of magnitude, respectively. With the extreme sensitivity and quantitativeness of the developed tool, we demonstrate development of PPI biomarkers that allow precision prediction of drug responses of individual tumors, even in cancer types without actionable genomic mutations. Thus, this suggests a path toward “personalized diagnosis of cancers at the PPI level”, which would expand the concept and scope of the targeted cancer therapy. This work is
supported by the Samsung Science and Technology Foundation (삼성미래기술육성재단).
Updated May 20, 2017
PROFESSIONAL EXPERIENCE 2017. 03 – Seoul National University, Associate Professor
Department of Biological Sciences
2016. 03 –2017.02 Yonsei University
Yonsei‐IBS Institute
2014. 02 –2016.02 KAIST, Associate Professor with tenure
Department of Physics
2014. 01 – Samsung Science and Technology Foundation, Principal Investigator
Fundamental Sciences, Physics discipline
2011. 04 – National Creative Research Initiative, Principal Investigator
Ministry of Science, ICT and Future Planning, South Korea
2010. 09 –2014.02 KAIST, Associate Professor
Department of Physics
2007. 10 –2010.08 KAIST, Assistant Professor
Department of Physics and KAIST Institute for the BioCentury
2006. 7 – 2007. 10 Howard Hughes Medical Institute, Research Associate
University of Illinois, Urbana‐Champaign
2005. 7 – 2006. 7 University of Illinois, Urbana‐Champaign, Research Associate
Department of Physics
2004. 9 – 2005. 6 Seoul National University, Research Fellow
Inter‐University Semiconductor Research Center
EDUCATION
2000. 3 – 2004. 8 Seoul National University, Ph.D. in Electrical Engineering
Thesis advisor: Prof. Sin‐Doo Lee
Thesis title: Control of Supramolecular Orderings by Patterned Surface
Microstructures for Liquid Crystal Displays and Artificial Lipid Rafts
1998. 3 – 2000. 2 Seoul National University, M.S. in Electrical Engineering
1994. 3 – 1998. 2 Seoul National University, B.S. in Electrical Engineering
HONORS & AWARDS 30 Young Scientists who will shine the future of South Korea (commemorated with the 30th anniversary of the
Pohang University of Science and Technology) (December 2016)
(포항공대 개교 30주년 기념, 한국을 빛낼 젊은 과학자 30인)
2015 FILA Basic Science Award (awarded by the Korean Academy of Science and Technology) (November 2015)
(제2회 FILA 기초과학상, 한국과학기술한림원)
Blue Ribbon Lecture, Korean Society of Molecular and Cellular Biology (January, 2015)
(한국분자세포생물학회 Blue Ribbon Lecture)
Selected as Principal Investigator of Samsung Science and Technology Foundation (one of two recipients in the
physics discipline), Samsung Science and Technology Foundation (November, 2013)
(삼성미래기술육성재단 연구책임자 선정)
Outstanding lecture award (2012 Fall Semester, Statistical Physics), College of Natural Science
(2012 자연과학대학 우수강의 교원), KAIST (Feb. 2013)
Outstanding research award, College of Natural Science
(2012 자연과학대학 우수연구 교원), KAIST (December, 2012)
2011 100 Outstanding Research Achievements funded by the Korean government
Selected as one of the Top 5 achievements, First placed in the basic science discipline
(16개 범부처 국가연구개발 우수성과 100선, TOP5 선정, 기초연구부문 최우수성과)
2011 50 Outstanding Research Achievements funded by the Ministry of Education and Science of Korea
(교육과학기술부 선정 기초연구 우수성과 50선)
2011 Selected as Principal Investigator of National Creative Research Initiative of Korea (April, 2011)
(2011 창의적 연구진흥과제 선정, 단분자 시스템 생물학 연구단)
Scientist of the Month, January 2011 awarded by the city of Daejeon
(대전광역시 수여 이달의 과학기술인 상, 2011년 1월)
Outstanding academic achievement award, 40th Anniversary of Foundation of KAIST
(KAIST 개교 40주년 기념 학술상) (Feb. 16, 2011)
SELECTED PUBLICATIONS
[1] J.‐K. Ryu, S. J. Kim, S.‐H. Rah, J. I. Kang, H. E. Jung, D. Lee, H.‐K. Lee, J.‐O. Lee, B. S. Park, T.‐Y. Yoon1 & H.
M. Kim1
Reconstruction of LPS Transfer Cascade Reveals Structural Determinants within LBP, CD14, and TLR4‐MD2 for
Efficient LPS Recognition and Transfer
Immunity 46, 38 (2016). 1 Corresponding author
Summary: Lipopolysaccharide (LPS), the major component of the
outer membrane of Gram‐negative bacteria, binds Toll‐like
receptor 4 (TLR4)‐MD2 complex and activates innate immune
responses. To define the sequential molecular interactions
underlying this transfer, we reconstituted in vitro the entire LPS
transfer process from LPS micelles to TLR4‐MD2. Using single‐
molecule approaches, we characterized the dynamic
intermediate complexes for LPS transfer: LBP‐LPS micelles, CD14‐
LBP‐LPS micelle, and CD14‐LPS‐TLR4‐MD2 complex. The
definition of the structural determinants of the LPS transfer
cascade to TLR4 may enable the development of targeted
therapeutics for intervention in LPS‐induced sepsis.
[2] D. Min, R. E. Jefferson, J. U. Bowie1 & T.‐Y. Yoon1
Mapping the energy landscape for second stage folding of a single membrane protein
Nature Chemical Biology 11, 981 (2015). 1 Corresponding author
‐‐ Featured in more than 10 media worldwide including Phys.org, EureaAlert! and Science Daily
In this work, we reported a single‐molecule method that allows folding study of membrane proteins in a lipid
bilayer environment. Our work suggests a moderate thermodynamic stability for an integral membrane
protein, but with a high kinetic energy barrier that imparts rigidity to the structure.
[3] J.‐K. Ryu, D. Min, S.‐H. Rah, S. J. Kim, Y. Park, H. Kim, C. Hyeon, H. M. Kim, R. Jahn1 & T.‐Y. Yoon1
Spring‐loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover
Science 347, 1485 (2015). 1 Corresponding author
‐‐ Featured in more than 30 media worldwide including EurekAlert!, ScienceDaily and PhysOrg
In this work, we reported that NSF disassembles the SNARE complex, the core machinery for membrane
fusion in all eukaryotes, with a spring‐loaded mechanism that exploits a single round of ATP turnover. This
answers a long‐standing question in the membrane trafficking field.
[4] W. Bae, K. Kim1, D. Min, J.‐K. Ryu, C. Hyeon & T.‐Y. Yoon1
Programmed folding of DNA origami structures through single‐molecule force control
Nature Communications 5, 5654 (2014). 1 Corresponding author
Design rules for DNA nanostructures have been remarkably advanced in recent years, but their folding
mechanism remains largely elusive. In this work, using single‐molecule magnetic tweezers, we demonstrated
a capability to control the folding pathway of DNA nanostructures for the first time.
[5] H.‐W. Lee, J. Y. Ryu, J. Yoo, B. Choi, K. Kim1 & T.‐Y. Yoon1
Real‐time single‐molecule co‐immunoprecipitation of weak protein‐protein interactions
Nature Protocols 8, 2045 (2013). (Invited contribution) 1 Corresponding author
[6] W. Bae, M.‐G. Choi, C. Hyeon1, Y.‐K. Shin1 & T.‐Y. Yoon1
Real‐Time Observation of Multiple Protein Complex Formation with Single‐Molecule FRET
JACS (communication) 135, 10254 (2013). 1 Corresponding author
‐‐ Featured in ASBMB today (American Society for Biochemistry and Molecular Biology)
‐‐ Featured in JACS Select for “Protein Dynamics Simulation and Experiments”
[7] D. Min, K. Kim, C. Hyeon, Y. H. Cho, Y.‐K. Shin1 & T.‐Y. Yoon1
Mechanical unzipping and rezipping of a single SNARE complex reveals large hysteresis as force‐generating
mechanisms
Nature Communications 4, 1705 (2013). 1 Corresponding author
‐‐ Recommended in F1000.com
[8] H.‐W. Lee, T. Kyung, J. Yoo, T. Kim, C. Chung, J. Y. Ryu, H. Lee, K. Park, S. Lee, W. D. Jones, D.‐S. Lim, C.
Hyeon, W. D. Heo1 & T.‐Y. Yoon1
Real‐time single‐molecule co‐immunoprecipitation analyses reveal cancer‐specific Ras signaling dynamics
Nature Communications 4, 1505 (2013). 1 Corresponding author
‐‐ Invited by Nature Protocols for contribution ‐‐ Highlighted in more than 30 Korean newspapers and
major media including KBS News 9, MBC News Desk and YTN News
In this work, we reported single‐molecule version of the co‐immunoprecipitation analysis that allows
application of single‐molecule imaging to endogenous, cellular proteins. Based on this work, we are now
developing a molecular diagnostics tool for targeted cancer therapy.
[9] H.‐K. Lee, Y. Yang, Z. Su, C. Hyeon, T.‐S. Lee, H.‐W. Lee, D.‐H. Kweon, Y.‐K. Shin1 & T.‐Y. Yoon1
Dynamic Ca2+‐Dependent Stimulation of Vesicle Fusion by Membrane‐Anchored Synaptotagmin 1
Science 328, 760 (2010). 1 Corresponding author
‐‐ Selected as Editors’ choice ‐‐ Selected as 2011 100 Outstanding Research Achievements funded by the
Korean government (Selected as one of the Top 5 achievements, First placed in the basic science discipline)
This work reports the first in vitro reconstitution of the fusogenic function of Synaptotagmin, which is the
main Ca2+ sensor of presynaptic fusion.
SELECTED PRESENTATIONS (during the last two years)
Plenary lecture at 18th Biophysics Conference and Annual Meeting of the Biophysics Society of ROC (Academia
Sinica, Taipei, June 29, 2013)
Invited talk at Frontiers in Membrane Protein Structural Dynamics 2014 (University of Chicago, May 7, 2014)
Invited talk at Gordon Research Conference on Single‐Molecule Approaches to Biology (Lucca, July 14, 2014)
Invited talk, Frontier in Biological Science Seminar series (Tsinghua University, Beijing, Oct. 8, 2014)
Invited talk, Blue Ribbon Lecture of Korean Society of Molecular and Cellular Biology (January 22, 2015)
Invited talk, Yonsei Nobel Forum 2015 for Dr. Randy W. Schekman (May 28, 2015)
Invited talk, Inaugural Gordon Research Conference on Membrane Protein Folding (Bentley University,
Waltham, USA, June 21‐26, 2015)
Invited talk, DGIST Global Innovation Festival (DGIF) 2015 (November 19, 2015)
Plenary talk, 2016 Annual Meeting of Korean Society for Structural Biology (July 4, 2016)
Invited talk, Third International Symposium on Protein Folding and Dynamics (November 10, 2016, Bangalore,
India)
Organizer, 1st Korea‐Japan Joint Symposium on Single‐Molecule Biophysics (November 26, 2016, Tsukuba,
Japan)
Invited talk, 31st Annual Symposium of the Protein Society (to be July 24‐27, 2017, Montreal, Canada)
PUBLICATIONS
[44] J.‐K. Ryu, S. J. Kim, S.‐H. Rah, J. I. Kang, H. E. Jung, D. Lee, H.‐K. Lee, J.‐O. Lee, B. S. Park, T.‐Y. Yoon1 & H.
M. Kim1
Reconstruction of LPS Transfer Cascade Reveals Structural Determinants within LBP, CD14, and TLR4‐MD2 for
Efficient LPS Recognition and Transfer
Immunity 46, 38 (2016). 1 Corresponding author
[43] J. Yoo, T.‐S. Lee, B. Choi, M. J. Shon & T.‐Y. Yoon
Observing Extremely Weak Protein‐Protein Interactions with Conventional Single‐Molecule Fluorescence
Microscopy
JACS (communication) 138, 14238 (2016).
[42] T.‐S. Lee, J.‐Y. Lee, J. W. Kyung, Y. Yang, S. J. Park, S. Lee, I. Pavlovic, B. Kong, Y. S. Jho, H. J. Jessen, D.‐H.
Kweon, Y.‐K. Shin, S. H. Kim1, T.‐Y. Yoon1 & S. Kim1
Inositol Pyrophosphates Inhibit Synaptotagmin‐Dependent Exocytosis
PNAS 113, 8314 (2016). 1 Corresponding author
‐‐Recommended in F1000.com
[41] J. Kim, H. Kang, J. Park, W. Kim, J. Yoo, N. Lee, J. Kim, T.‐Y. Yoon & G. Choi
PIF1‐interacting transcription factors and their binding sequence elements determine the in vivo targeting
sites of PIF1
Plant Cell, Advance online publication.
[40] J.‐K. Ryu, R. Jahn1 & T.‐Y. Yoon1
Progresses in understanding NSF‐mediated disassembly of SNARE complexes
Biopolymers 105, 518 (2016).
‐‐Invited review
‐‐Special Issue for GTP and ATP Hydrolysis in Biology, edited by Alfred Wittinghofer 1 Corresponding author
[39] D. Min, R. E. Jefferson, J. U. Bowie1 & T.‐Y. Yoon1
Mapping the energy landscape for second stage folding of a single membrane protein
Nature Chemical Biology 11, 981 (2015). 1 Corresponding author
‐‐ Featured in more than 10 media worldwide including Phys.org, EureaAlert! and Science Daily
[38] L. Zhang, Q. Feng, J. Wang, S. Zhang, B. Ding, Y. Wei, M. Dong, J.‐Y. Ryu, T‐.Y. Yoon, X. Shi, J. Sun, & X.
Jiang
Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility‐
Regulated Cell‐Nanoparticle Interaction
ACS Nano 9, 9912 (2015).
[37] J.‐K. Ryu, D. Min, S.‐H. Rah, S. J. Kim, Y. Park, H. Kim, C. Hyeon, H. M. Kim, R. Jahn1 & T.‐Y. Yoon1
Spring‐loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover
Science 347, 1485 (2015). 1 Corresponding author
‐‐ Featured in more than 30 media worldwide including EurekAlert!, ScienceDaily and PhysOrg
[36] W. Bae, K. Kim1, D. Min, J.‐K. Ryu, C. Hyeon & T.‐Y. Yoon1
Programmed folding of DNA origami structures through single‐molecule force control
Nature Communications 5, 5654 (2014). 1 Corresponding author
[35] J. Y. Ryu, I. T. Song, K.H.A. Lau, P. B. Messersmith, T.‐Y. Yoon1, and H. Lee1
New Anti‐fouling Platform Characterized by Single‐molecule Imaging
ACS Applied Materials & Interfaces 6, 3553 (2014). 1 Corresponding author
[34] Y. Lai, X. Lou, Y. Jho, T.‐Y. Yoon1 & Y.‐K. Shin1
The synaptotagmin 1 linker may function as an electrostatic zipper that opens for docking but closes for
fusion pore opening
Biochemical Journal 456, 25 (2013). 1 Corresponding author
[33] H.‐W. Lee, J. Y. Ryu, J. Yoo, B. Choi, K. Kim1 & T.‐Y. Yoon1
Real‐time single‐molecule co‐immunoprecipitation of weak protein‐protein interactions
Nature Protocols 8, 2045 (2013). (Invited contribution) 1 Corresponding author
[32] W. Bae, M.‐G. Choi, C. Hyeon1, Y.‐K. Shin1 & T.‐Y. Yoon1
Real‐Time Observation of Multiple Protein Complex Formation with Single‐Molecule FRET
JACS (communication) 135, 10254 (2013). 1 Corresponding author
‐‐ Featured in ASBMB today (American Society for Biochemistry and Molecular Biology)
‐‐ Featured in JACS Select for “Protein Dynamics Simulation and Experiments”
[31] D. Min, K. Kim, C. Hyeon, Y. H. Cho, Y.‐K. Shin1 & T.‐Y. Yoon1
Mechanical unzipping and rezipping of a single SNARE complex reveals large hysteresis as force‐generating
mechanisms
Nature Communications 4, 1705 (2013). 1 Corresponding author
‐‐ Recommended in F1000.com
[30] H.‐W. Lee, T. Kyung, J. Yoo, T. Kim, C. Chung, J. Y. Ryu, H. Lee, K. Park, S. Lee, W. D. Jones, D.‐S. Lim, C.
Hyeon, W. D. Heo1 & T.‐Y. Yoon1
Real‐time single‐molecule co‐immunoprecipitation analyses reveal cancer‐specific Ras signaling dynamics
Nature Communications 4, 1505 (2013). 1 Corresponding author
‐‐ Invited by Nature Protocols for contribution
‐‐ Highlighted in more than 30 Korean newspapers and major media including KBS News 9, MBC News Desk
and YTN News
[29] S. Cho, J. Jang, C. Song, H. Lee, P. Ganesan, T.‐Y. Yoon, M. W. Kim, M. C. Choi, H. Ihee, W. D. Heo & Y. K.
Park
Simple super‐resolution live‐cell imaging based on diffusion‐assisted Förster resonance energy transfer
Scientific Reports 3, 1028 (2013).
[28] S. Heo, K. Kim, R. Christophe, T.‐Y. Yoon & Y.‐H. Cho
Simultaneous detection of biomolecular interactions and surface topography using photonic force
microscopy
Biosensors and Bioelectronics 42, 106 (2013).
[27] J. Diao, Y. Ishitsuka, H. Lee, C. Joo, Z. Su, S. Syed, Y.‐K. Shin, T.‐Y. Yoon & T. Ha
A single vesicle‐vesicle fusion assay for in vitro studies of SNAREs and accessory proteins
Nature Protocols 7, 921 (2012).
[26] J.‐H. Kang, K. Kim, H.‐S. Ee, Y.‐H. Lee, T.‐Y. Yoon, M.‐K. Seo & H.‐G. Park
Low‐power nano‐optical vortex trapping via plasmonic diabolo nanoparticles
Nature Communications 2, 582 (2011).
[25] M.‐H. Seo, T.‐S. Lee, E. Kim, Y. L. Cho, H.‐S. Park, T.‐Y. Yoon1 & H. S. Kim1
Efficient Single‐Molecule Fluorescence Resonance Energy Transfer Analysis by Site‐Specific Dual‐Labeling of
Protein Using an Unnatural Amino Acid
Analytic Chemistry 83, 8849 (2011). 1 Corresponding author
[24] T.‐Y. Yoon, D.‐H. Kweon & Y.‐K. Shin
Chasing the Trails fo SNAREs and Lipids Along the Membrane Fusion Pathway (Invited Review)
Current Topics in Membranes 68, 161 (2011).
[23] C. Jeong, W.‐K. Cho, K.‐M. Song, C. Cook, T.‐Y. Yoon, C. Ban, R. Fishel & J.‐B. Lee
MutS Switches Between Two Fundamentally Distinct Clamps during Mismatch Repair
Nature Structural and Molecular Biology 18, 279 (2011).
[22] Y. Yang, J. Y. Shin, J.‐J. Oh, C. H. Jung, Y. Hwang, S. Kim, J.‐S. Kim, K.‐J. Yoon, J.‐Y. Ryu, J. Shin, J. S. Hwang,
T.‐Y. Yoon, Y.‐K. Shin & D.‐H. Kweon
Dissection of SNARE‐driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules
into the SNARE zipper
PNAS 107, 22145 (2010).
[21] H.‐K. Lee, Y. Yang, Z. Su, C. Hyeon, T.‐S. Lee, H.‐W. Lee, D.‐H. Kweon, Y.‐K. Shin1 & T.‐Y. Yoon1
Dynamic Ca2+‐Dependent Stimulation of Vesicle Fusion by Membrane‐Anchored Synaptotagmin 1
Science 328, 760 (2010). 1 Corresponding author
‐‐ Selected as Editors’ choice
‐‐ Selected as 2011 100 Outstanding Research Achievements funded by the Korean government (Selected as
one of the Top 5 achievements, First placed in the basic science discipline)
[20] J. Diao, Z. Su, T.‐Y. Yoon, Y.‐K. Shin & T. Ha
Single‐Vesicle Fusion Assay Reveals Munc18‐1 Binding to the SNARE Core is Sufficient for Stimulating
Membrane Fusion
ACS Chem. Neurosci. 1, 168 (2010).
[19] Y. Na, T.‐Y. Yoon, S. Park, B. Lee & S.‐D. Lee
Electrically Programmable Nematofluidics with a High Level of Selectivity in a Hierarchically Branched
Architecture
Chem. Phys. Chem. 11, 101 (2009).
[18] J. Diao, T.‐Y. Yoon, Z. Su, Y.‐K. Shin & T. Ha
C2AB: A molecular glue for lipid vesicles with a negatively charged surface
Langmuir 13, 7717 (2009).
[17] T.‐Y. Yoon1 & Y.‐K. Shin1
Progress in understanding the SNARE function and its regulation (Invited Review)
Cell. Mol. Life Sci. 66, 460 (2009). 1 Corresponding author
[16] T.‐Y. Yoon1, X. Lu1, J. Diao1, T. Ha, & Y.‐K. Shin
Complexin and Ca2+ stimulate SNARE‐mediated membrane fusion.
Nature Structural and Molecular Biology 15, 707 (2008). 1 These authors equally contributed to this work.
Before the Yoon Lab
[15] T.‐Y. Yoon1, B. Okumus1, F. Zhang1, Y.‐K. Shin & T. Ha
From the Cover: Multiple intermediates in SNARE‐induced membrane fusion.
Proc. Natl. Acad. Sci. USA. 103, 19731 (2006). 1 These authors equally contributed to this work.
‐‐ Featured in This Week in PNAS
‐‐ Featured in Commentary of PNAS (PNAS 103, 19611 (2006))
‐‐ Featured in News and Views of Nat. Struct. Mol. Biol. (Nat. Struct. Mol. Biol. 14, 13 (2007))
[14] Y.‐T. Kim, J.‐H. Hong, T.‐Y. Yoon & S.‐D. Lee
Pixel‐encapsulated flexible displays with a multifunctional elastomer substrate for self‐aligning liquid crystals.
Applied Physics Letters 88, 263501 (2006).
[13] T.‐Y. Yoon, C. Jeong, S.‐W. Lee, J. H. Kim, M. C. Choi, S.‐J. Kim, M. W. Kim & S.‐D. Lee
Topographic control of lipid‐raft reconstitution in model membranes.
Nature Materials 5, 281 (2006).
[12] C. Jeong, T.‐Y. Yoon, S.‐D. Lee, Y.‐G. Park & H. Kwon
Patterning Process of Membrane‐Associated Proteins on a Solid Support with Geometrical Grooves.
Mol. Cryst. Liq. Cryst. 434, 297 (2005).
[11] T.‐Y. Yoon, C. Jeong, J. H. Kim, M. C. Choi, M. W. Kim & S.‐D. Lee
Spontaneous aggregation of lipids in supported membranes with geometrical barriers.
Applied Surface Science 238, 299 (2004).
[10] T.‐Y. Yoon, C. Jeong, S.‐J. Kim, C.‐J. Yu & S.‐D. Lee
UNDULATION PATTERNS IN PATTERN FORMATION OF CHOLESTERIC LIQUID CRYSTALS AS WAVELENGTH‐CHANGING
INSTABILITIES.
Mol. Cryst. Liq. Cryst. 413, 489 (2004).
[9] J.‐H. Park, Y. Choi, T.‐Y. Yoon, C.‐J. Yu & S.‐D. Lee
A self‐aligned multi‐domain liquid‐crystal display on polymer gratings in a vertically aligned configuration.
Journal of the Society for Information Display 11, 283 (2003).
[8] T‐Y. Yoon, J.‐H. Park, J. Sim & S.‐D. Lee
Self‐formation of microdomains by the topographical and fringe field effects in a liquid crystal display with
dielectric surface gratings.
Applied Physics Letters 81, 2361 (2002).
[7] T.‐Y. Yoon, C.‐J. Yu, W.‐J. Lee, J.‐S. Sim, J.‐H. Park & S.‐D. Lee
Control of electric equi‐potential in a liquid crystal film on a grating surface.
Opt. Mater. 21, 647 (2002).
[6] Y.‐J. Cho, T.‐Y. Yoon, S.‐D. Lee & H.‐W. Rhee
Laser Etchings on Polyimide Alignment Layers in Multi‐Domain VA Mode.
Mol. Cryst. Liq. Cryst. 377, 317 (2002).
[5] T.‐Y. Yoon, J.‐H. Park, W.‐J. Lee & S.‐D. Lee
Self‐Induced Array of Micro‐Domains in a Twisted Nematic Structure on a Surface Geometric Grating.
Mol. Cryst. Liq. Cryst. 375, 215 (2002).
[4] J.‐H. Park, T.‐Y. Yoon, W.‐J. Lee & S.‐D. Lee
Multi‐domain Liquid Crystal Display with Self‐Aligned 4‐Domains on Surface Relief Gratings of Photopolymer.
Mol. Cryst. Liq. Cryst. 375, 433 (2002).
[3] T.‐Y. Yoon, H. Baac, & S.‐D. Lee
Optical Properties of a Chiral Liquid Crystal in a Generalized Coupled Mode Formalism.
Mol. Cryst. Liq. Cryst. 371, 203 (2002).
[2] T.‐Y. Yoon & S.‐D. Lee
Analysis of the Optical Properties of a Helicoidal Liquid Crystal in a General Coupled Mode Formalism.
Mol. Cryst. Liq. Cryst. 366, 387 (2001).
[1] J.‐H. Lee, H.‐R. Kim, T.‐Y. Yoon & S.‐D. Lee
Wavelength Selection in a Fabry‐Perot Filter with an Axially Aligned Nematic Liquid Crystal.
Mol. Cryst. Liq. Cryst. 337, 19 (1999).