The R&D landscape in the State of São Paulo,...
Transcript of The R&D landscape in the State of São Paulo,...
Carlos H. de Brito Cruz
Science Director
FAPESP
Shell-FAPESP Workshop on Offshore R&D, 20200303
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The R&D landscape in the State of São Paulo, Brazil
Outline
• R&D in the State of São Paulo, Brazil
– The São Paulo Research Foundation, FAPESP
• A bird’s eye view on R&D results in São Paulo
– The challenge of obtaining more impact from research in three dimensions: Scientific, Social, Economic
• Research collaboration strategy
– Research collaboration across geographies and institutions
– University-Industry joint R&D
– Start-ups and Small Business R&D
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State of São Paulo, Brasil
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42 million people
32% of Brazil’s GDP
45% of Brazilian Science
7,319 PhDs graduated in 2017
39% of the PhDs graduated in Brazil
12% of State budget to HE and R&D
1.3% GDP for R&D (2017)
São Paulo: 69,600 researchers, 151 institutions, 15,000 innovative companies
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FAPESP: São Paulo Research Foundation
• Mission: support research in all fields• Funded by the State of SP: 1% of all tax revenues• All proposals are peer reviewed (26,000 in 2018)
– Time for decision ~ 70 days; 41% success rate
• Expenditures: R$ 1.266 billion in 2019– Fellowships
• In Brazil: 2,500 SI, 1,150 MSc, 2,400 DrSc, 1,700 Post-docs• Abroad: 1,200 per year
– Academic R&D• 17 Centers (11-yrs dur.), 400 Thematic (5-yrs), 300 Young Investigators (5-yrs), 2,800 Regular (2-
yrs)
– University-Industry Joint R&D: Microsoft, Vale, Petrobrás, Embraer, Boeing, etc.• 14 Engineering Res. Centers: 10 years joint grants FAPESP/Industry – PCBA, GSK, BG/Shell,
Embrapa, …
– Small business R&D (PIPE): 1,500 SBE’s (247 contracts in 2019, many start-ups)
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BASIC, APPLIED, ACADEMIC, BUSINESS RESEARCH
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Researchers in São Paulo, Brazil publish more than any Latin American country
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0
5000
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20000
25000
30000Number of articles per year (Clarivate, Incites)
SAO PAULO; BRAZIL MEXICO ARGENTINA CHILE COLOMBIA PERU VENEZUELA
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Higher productivity sugarcane:84 → 148 → 212 → 381 ton/Ha??
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1980-2013: change in energy sources in the State of São Paulo, Brazil
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Oil and oil products
Hydroelectricity
Sugar cane
Other
Natural gas
14%
62%
32%
38%
State of São Paulo
• 42 million people
• 32% of Brazil’s GDP
• 55% of Brazilian
ethanol production
1980 – 2013
• Oil down from 62% to 38%
• Cane up from 14% to 32%
Source: Balanço Energético SP, 2008-2014 (values from 1980-1990 interpolated for visualization)
SIRIUS, Brazilian Synchrotron Light Source:LINAC and Booster inaugurated on Nov , 2018
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Unicamp: 821 start-ups; 717 active; 31,143 jobs, R$ 7.9 billion in revenues (2019)
benchmarking-20200209.pptx; © C.H. Brito Cruz e Fapesp 123/4/2020
USP: 1,154 companies, 6 unicorns, R$ 60 billion income (2018)
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Embraer-FAPESP: R&D to build an innovative jet
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Computational Fluid Dynamics (CFD)
modelling and tests
R&D co-funded by FAPESP, several
universities
University-Business co-authorship in Brazil –exponential growth
benchmarking-20200209.pptx; © C.H. Brito Cruz e Fapesp 153/4/2020
0
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WoS items with co-authorship between universities in Brazil and companies
Escala logaritimica: +14% por ano
Engineering Research Centers at FAPESP: Advanced Joint University/Industry Research
• A long-term plan for Advanced Research
• Center is hosted in a university/institute, – Center Director is a professor/researcher
– Adjunct Director is a researcher from the company as a visiting professor at the university
– Other company researchers participate as visiting professors
• Up to 10-years contract, w. reviews on years 3, 5, 7
• Cost sharing: FAPESP: Industry: University ̴ 1:1:2– US$ 0.5 – 4 million per year from FAPESP and Company, plus labor
and infrastructure costs by university
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Engineering Research Centers: R$ 1,02 billion in contracts; FAPESP+Business+Host (Univ/Res Inst)
1. Peugeot-Citroen/Unicamp: Biofuel Engines Engineering Research Center2. 10+ Pharmas/SGC/Unicamp/Oxford/Toronto/N. Carolina: Structural Genomics Center @ Unicamp3. GSK/I. Butantan: Engineering Research Center on Target Discovery4. GSK/UFSCAR: Engineering Research Center on Sustainable Chemistry5. Shell (British Gas)/USP: Engineering Research Center on Natural Gas6. Natura/USP: Applied Research Center on Well-being and Human Behavior7. Embrapa/Unicamp: Agriculture, Gene Editing, Climate Change8. Shell (BG)/Unicamp/USP/IPEN: New Energy
1. Shell (BG)/Unicamp: Dense Energy Carriers2. Shell (BG)/USP: Computational Materials Sciences3. Shell (BG)/Unicamp: Advanced Energy Storage4. Shell (BG)/IPEN: Methane2Products
9. Equinor/Unicamp: Oil Reservoirs10. Koppert/USP: Biological Control11. Usina S. Martinho/Unesp: Biological Control for Sugarcane12. IBM/USP: Artificial Intelligence13. Call open for 2 more centers on IA
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An internationally connected R&D hub in São Paulo, Brazil
• Good supply of qualified researchers
• Stably funded universities and research agency
• Intense, and growing, industrial R&D
– University-Industry R&D collaboration
– Lively start-up scene
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CONCLUSION
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FT, CB Insights: São Paulo as a Tech-hub
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Colaborações em Pesquisa - China
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FAPESP-NIH-Butantan: Tetravalent Dengue vaccine
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Colaborações em Pesquisa - China
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São Paulo, Brazil: University-Business co-authorship in scientific articles
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Main partners
Petrobras
Novartis
Pfizer
Roche
GSK
IBM
Vale/ITV
Merck
Eletrobras
AstraZeneca
Fibria
Westat
Janssen
Embraer
Bayer
Monsanto
Agilent
Braskem
Boehringer Ingelheim
Sanofi
A growing list of high impact research results……
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SOAR: Southern Observatory for Astrophysical Research
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J.B. Haislip et al., “A photometric redshift of z = 6.39 0.12 for GRB 050904”,
Nature 440, 181-183 (9 March 2006).
Infrared afterglow observation after a GRB -unveils the explosion which happened 13 billion years ago.These results demonstrated that GRBs can be used to trace the star formation, metallicity, and reionization histories of the early Universe.
USP, UFRGS, UNC Ch.Hill
Fapesp, CNPq, NSF,...
Starting 2014:
Personalized medicine
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FAPESP’s Center for Cellular Therapyhosted at USP’s Hemocenter, Ribeirão Preto
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Monoclonal antibodies: Recepta – Mersanaagreement
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Advanced Molecular Biology for Agriculture and Health
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Brazil Energy Supply - 2016
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NON-RENEWABLEENERGY
RENEWABLE ENERGY
Brazil 2016, PES
Starting with a MSc dissertation on “Cooperative multirobot localization…”..
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…to an idea….+ funding from FAPESP …+IP protection….
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…ao produto e empresa
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Hoobox is at J&J Innovation Labs, Houston
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Destruir tumor cerebral com virus Zika sem afetar as células boas
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Usar vírus Zika para acabar
com o tumor sem afetar as
células normais. Super
resultado de Oswaldo
Okamoto, Carolini Kaid,
Mayana Zatz e equipe da
USP com apoio da FAPESP.
https://youtu.be/u_uoaa2Ua
ME
PIPE, FAPESP: Aumento no emprego
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http://revistapesquisa.fapesp.br/2017/12/28/o-maior-programa-de-estimulo-a-inovacao/
O impacto no nível de emprego
das empresas envolvidas é
expressivo: • aumento de 40% nos
recursos humanos
(contratados, terceirizados e
bolsistas)
• aumento de quase 30% no
pessoal contratado
diretamente que levou à
ampliação, até um ano após
o encerramento do projeto• de 60% do pessoal de
nível superior
• de mais de 90% do pessoal
com pós-graduação
Start-ups created by students and faculty at Unicamp, 1974-2015
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Engineering Research Centers: R$ 1,02 billion in contracts; FAPESP+Business+Host (Univ/Res Inst)
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Themes Company/Univ/Res. Ins.FAPESP
(est 10-yr)Company(est 10-yr)
Hosts(est 10-yr)
Biofuel automobile engines Peugeot-Citroen+Unicamp and others R$ 11 M R$ 8 M R$ 15 M
Green Chemistry GSK+Ufscar e outras R$ 12 M R$ 57M R$ 42M
Target discovery GSK+Inst. Butantan R$ 26 M R$ 23M R$ 67M
Natural Gas Shell/BG+Poli, USP and others R$ 46 M R$ 58M R$ 42M
Human well-being Natura+Inst. Psicologia, USP+ R$ 9 M R$ 10M R$ 22M
Agriculture,Climate Change,Gene Editing EMBRAPA+Unicamp R$ 25 M R$ 33M R$ 45M
New Energy (1 hub, 4 spokes) Shell/BG+Unicamp, IPEN, USP-SC R$ 42 M R$ 65 M R$ 158 M
Oil and Gas Reservoirs Statoil/Equinor+Unicamp and others R$ 34 M R$ 26 M R$ 125 M
Biological Control in Agriculture Koppert R$ 6,9M R$ 5M R$ 6,3M
Biological Control for Sugarcane Usina São Martinho
Artificial Intelligence IBM
Digital Technologies for Oil and Gas Petrobrás
Aerodynamics, Computational Fuidodynamics
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Brazil: State R&D expenditures, 2015
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Source: Indicadores C&T, MCTI
8 x
29 x
BRIC and OECD countries: % renewables in Total Primary Energy Supply, by type
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From: IEA, Renewables Information 2017, Part II, Table 3 p. II.5
Brasil, São Paulo, Brasil fora de São Paulo
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Brasil São Paulo Brasil sem São Paulo
Basic research applied to real problems
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