Pain e41

and non-controlled observational studies that examine the adverse events

of opioids).

Interventions: This systematic review will assess risk of bias, using an

instrument developed for the current review, quality of reporting, using the

McHarm (often considered the gold standard for assessing the reporting of

harms), and the incidence and prevalence of the reported adverse events of

prescription opioids.

Main Outcome Measure(s): The score each study receives for risk of bias

and quality of reporting, and the reported incidence and prevalence of the

adverse events of prescription opioids across all included studies.

Results: The score each study receives for risk of bias and quality of

reporting, and the reported incidence and prevalence of the adverse events

of prescription opioids across all included studies.

Conclusions: These findings suggest that the literature on the adverse

events of prescription opioids needs to be further evaluated and improved.

Key Words: Drug-Related Side Effects and Adverse Reactions, Opi-

oids, Review

Disclosure(s): None Disclosed.

Poster 110

The Relationship Between Tai Chi Posture and Knee Pain

Mei-Chi Hsieh (Chang Gung University), Yang-Hua Lin

Objective: To investigate the relations betweenTaiChi posture and knee pain.Design: Questionnaire Survey.

Setting: A recreational community.

Participants: Tai Chi Chuan practitioners.

Interventions: Not applicable.Main Outcome Measure(s): A questionnaire consists of 25 questions

including demographic information, experience of Tai Chi Chuan, daily

activities, medical history of knee, and The International Knee Docu-

mentation Committee Subjective Knee Evaluation Form (IKDC form).

Data are striated according to characteristic, including the occurrence of

knee pain (ever or never happened), height of knee postures (low, middle,

high), age (below 45 year-old, 45-60 year-old, above 65 year-old),

gender, medical history (whether or not) and exercise pattern (Tai Chi

exercise only, has another regular exercise). Calculate IKDC score and

compare to normative data. Chi-Square test is applied in this research.

There were 47% practitioners had the experience of knee pain after

practicing Tai Chi. The average IKDC score of these respondents

was 82.02.

Results: The questionnaire was collected from 75 volunteers. The

average IKDC score of Tai Chi practitioners (82.02) was higher than the

normative data (80.89). There were significant correlations between

knee pain and height of knee postures. A low posture had significantly

higher possibility of causing knee pain (pZ0.0035). Comparing to Tai

Chi postures, the effect of gender, age, medical history of knee and

exercise pattern on knee pain did not show the difference statisti-

cally (P>0.05).

Conclusions: Tai Chi practitioners have better knee function. However,

about half of participants experienced knee pain after practicing Tai Chi.

Having knee pain after practicing is significantly related to the height of

knee postures during Tai chi practice.

Key Words: Tai Chi, Knee Joint, Pain, Elderly, Tai Chi Chuan

Disclosure(s): None Disclosed.

Poster 111

The Impact of Frequent Knee Pain and Obesity on Gait Speed: Datafrom the OAI Study

Saad M. Bindawas (King Saud University), Vishal Vennu, Soham Al Snih

Objective: To examine the impact of frequent knee pain (KP) and obesity

on gait speed (GS) among older men and women.

Design: Prospective cohort study.

Setting: This study used data from the Osteoarthritis Initiative (OAI) study.

www.archives-pmr.org

Participants: At baseline, 1296 men and 1822 women aged between 45-79

years with full data were selected for this study. We grouped participants

into four categories according to frequent KP and obesity status: having

neither frequent KP nor obesity, frequent KP only, obesity only, or frequent

KP and obesity.

Interventions: None.Main Outcome Measure(s): Gait speed was measured by using the 20-

meter timed walk test. The frequent KP was assessed with a self-report

questionnaire and the obesity was assessed by using Body Mass Index

(BMI) (30 kg/m2 or greater). General linear mixed models were con-

ducted. Information was collected at baseline, 12, 24, 36, 48 and

72 months.

Results: After adjusting for all covariates, frequent KP, obesity or both

conditions were associated (p <.0001) with declined GS in men (Estimate

Z -0.077, SEZ 0.020), (EstimateZ -0.054, SEZ 0.013) or (EstimateZ-0.083, SE Z 0.019) respectively; and in women (Estimate Z -0.084, SE

Z 0.018), (Estimate Z -061, SE Z 0.010) or (Estimate Z -0.102, SE Z0.001) respectively.

Conclusions: Our results suggest that both frequent KP and obesity are asso-

ciated with declined gait speed over time; and declined faster among women.

Key Words: obesity, knee pain, gait speed

Disclosure(s): None Disclosed.

Poster 112

WITHDRAWN

Poster 113

Association Between Musculoskeletal Pain, Overweight and Obesityand Physical Function in Nursing Home Employees

Winnie Szu Yun Chin (University of Connecticut), Pouran D. Faghri,Tania Huedo-Medina

Objective: To determine the extent musculoskeletal (MS) pain in the low

back, knee (weight-bearing joints), shoulder, and wrist (non-weight-

bearing joints), mediates associations between obesity levels based on BMI

(4 levels: overweight, obese class I, II or III), physical function, physical

activity levels and exercise self-efficacy.

Design: Cross-sectional study.Setting: Four long-term nursing home facilities in the Northeast U.S.

Participants: Ninety-nine overweight or obese (BMI � 25) nursing

home employees.

Interventions: Self-reported survey administered to employees who met

inclusion and exclusion criteria.

Main Outcome Measure(s): SF-12 (physical function), the Exercise Self-

Efficacy Scale (ESE), level of physical activity and frequency of pain

experienced at each joint.

Results: Reported frequency of pain were 66.3%, 54.4%, 42.2%, and

24.1% for lower back (LBP), knee, shoulder, and wrist, respectively.

Higher levels of obesity and LBP were associated with lower general

health status (bZ-0.199, p<0.05). Physical activity was lower among

those with higher obesity levels (bZ-0.288, p<0.001), especially in

days performing moderate and vigorous activity (bZ-0.336, p<0.001;

bZ-0.199, p<0.05). Level of obesity, LBP, and wrist pain, were associated

with lower self-efficacy (bZ-0.245, p<0.05; bZ-0.274, p<0.05). Level of

obesity and pain in all sites were significantly associated (p<0.05) with

lower physical function, with mediating indirect effects of pain ranging

from -0.010 to -0.019.

Conclusions: Nursing home employees are at higher risk for developing

musculoskeletal disorders due to high demand, low control jobs, and the

associated biomedical compromises while working. To increase the

effectiveness of weight loss interventions for this population, the comor-

bidity and the mediating effects of MS pain with higher levels of obesity

should be considered.

Key Words:Musculoskeletal Pain, Obesity, Quality of Life, Physical Function

Disclosure(s): None Disclosed.