0

5

10

15

20

25

30

35

40

Serology 0 1 1 1 0 0 1

DNA 11 3 6 12 12 20 20

Serology+DNA 0 4 9 11 12 13 15

TOTAL 11 8 16 24 24 33 36

EPT-

1

(2004

EPT-

2

(2005

EPT-

3

(2006

EPT-

4

(2007

EPT-

5

(2008

EPT-

6

(2009

EPT-

7

(2010

BEPT enrollment

44%

56%

TURKEY

BALKANCOUNTRIES

DISTRIBUTION OF PARTICIPANTS

n: 16

n: 20

SEROLOGY+DNA

DNA

SEROLOGY

TYPE OF THE REQUESTS

n: 20

n: 15

n: 1

SEROLOGY+DNA

DNA

SEROLOGY

3%

20%

11%

26%

40%

SSP

SSP+Luminex

SSP+SSO

Luminex

SSO+Luminex

METHODS IN BEPT (2010)CLASS I & II TYPING

Samples were dispatched on 7-8 December 2010

0

10

20

30

40

50

60

70

80

90

100

S#1 S#2 S#3 S#4 S#5 S#6 S#7 S#8 S#9S#10

%

BEPT-2010 CONSENSUS REPORT FOR SEROLOGICAL TYPING

***

*

100% consensus 38% consensus

0

10

20

30

40

50

60

70

80

90

100

D#1D#2D#3D#4D#5D#6 D#7D#8D#9D#10

%

BEPT-2010 CONSENSUS REPORT FOR CLASS I DNA TYPING

*

***

100% consensus 49% consensus

0

10

20

30

40

50

60

70

80

90

100

D#1D#2D#3D#4D#5D#6 D#7D#8D#9D#10

%

BEPT-2010 CONSENSUS REPORT FOR CLASS II DNA TYPING

*** ***

*

100% consensus

49% consensus

Nomenclature Mistakes

Serology 0 centerClass I DNA 13 centersClass II DNA 17 centers

Class I DNA

Class II DNA

Participant laboratories must report their findings using the correct nomenclature relevant to the methodology used.

Serology

Class I DNA

Class II DNA

Erroneous results

Serology 11 centersClass I DNA 13 centersClass II DNA 7 centers

discrepancy

Serology

Class I DNA

Class II DNA

Missing alleles

Serology 7 centersClass I DNA 1 centersClass II DNA 2 centers

Missing allele

36 LABS PARTICIPATED BEPT 2010

Centers stated to participate the tests however did not send the results

Serology A,B 1 center

Class I DNA A 0 centerB 0 centerC 5 centers

Class II DNA DR 0 centerDQ 2 centers

Problems in BEPT 2010 HLA Typing

Modification of the result submission forms (3 centers did not even use the forms we have sent)

No response about the delivery date of the samples(23 centers did not inform the date of sample delivery)

Results of 7 rounds of Region 8 BEPTfor HLA typing

has been submitted as a poster presentation to

EFI Congress to be held in Prag in May 2011.