SPECIAL REPORT: LEARNING THE TRUTH ABOUT REVERSING ...

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SPECIAL REPOR T: LEARNING THE TRUTH ABOUT RE VERSING DIABE TES

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Reversing Your Type 2 Diabetes

“Among the 34.2 million people in the United States who have been diagnosed with diabetes, many feel a sense of dread at what

seems like a life sentence.”

hether you suffer from diabetes, thyroid disease, autoimmune disease, or any number of other chronic and degenerative disorders, Next Advanced Medicine (NAM) is dedicated to digging deep clinically to identify the

causes of your physical condition and restoring your health. Next Advanced Medicine is an interdisciplinary medical practice in Orange County, California, that focuses on reversing disease, not treating symptoms. Their multidisciplinary team of medical doctors, naturopaths chiropractors, and nutrition scientists focuses on the whole patient; considering the complex confluence of genetic, environmental, and lifestyle factors that affects disease progression and treatment.

One of Next Advanced Medicine’s most profound messages is that of hope: remission for type 2 diabetes and other chronic diseases is possible. Thousands of patients have been able to reverse their disease, reduce and eliminate medicine and insulin injections, lose weight without exercise and radical diets, reduce and eliminate the risks for diabetic complications and early death, and even become nondiabetic. The purpose of this paper is to demonstrate the effectiveness of their approach to reversing diabetes and other chronic conditions, and to spread the word to those suffering from a chronic illness that there is a path out of sickness and into health.

THE REAL PROBLEMAmong the 34.2 million people in the United States who have been diagnosed with diabetes, many feel a sense of dread at what seems like a life sentence. No one is truly prepared to receive that intimidating diagnosis, but the prevalence isn’t surprising. The rate of obesity among children and adolescents ages 2 to 19 is 18.5%; while diabetes is known as a middle-age or older-age condition, it is affecting younger people at higher rates, particularly in cases where risk factors like obesity are present (CDC, 2020; CDC 2017).

These troubling statistics are part of a larger pattern: the lifestyle disease epidemic in the United States. Lifestyle diseases are chronic, noncommunicable diseases that are often the result of environmental factors. They include heart disease, asthma, cancer, and diabetes. These often-preventable diseases afflict six in 10 American adults, killing more than 1.7 million Americans every year, meaning they’re responsible for seven out of every 10 US deaths.

When patients are diagnosed with diabetes, their doctor likely recommends two things: losing weight and taking medication to help control blood sugar. But these fixes don’t get to the heart of the problem. There are major forces at play that make it difficult to treat diabetes, let alone reverse it with a pharmaceutical approach.

W

PATIENT EDUCATION SERIESA TRUE SOLUTION FOR TYPE 2 DIABETES

DR. CANDICE HALL, D.C.Dr. Candice Hall, DC is an author, speaker, practitioner, and authority on integrative and functional medicine. She is founder of NAM, a functional medicine practice

in Orange County, CA.

DR. WAYNE GREATHOUSE, D.C.Dr. Wayne Greathouse, D.C., After

obtaining degrees in both biochemistry and physiology as well as a doctorate in

chiropractic medicine.

DR. NEIL K. HERSH, M.D.Dr. Hersh is the Director of Medicine at NAM. He Attended Yale University, The

University of California at San Diego, and completed medical school at the

University of Chicago.

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Additionally, diabetes causes problems at a cellular level:At the time of [Type 2 diabetes] diagnosis, beta cells often are producing as much or more insulin as would be needed by someone else of equal weight. But changes in liver, fat and muscle cells have created resistance to insulin. Fat cells are not responsive to insulin, so they begin releasing free fatty acids into the bloodstream and these worsen the response to insulin. The liver does not respond to insulin so it is less able to turn off its production and release of glucose, and the blood sugar rises further. Cells in the muscles would normally pick up glucose from the blood, but insulin resistance weakens this effort. All these cellular changes cause damaging fat and sugar levels to rise in the blood.—Diabetes Services, Inc.

THE US FOOD SYSTEM AND THE PHARMACEUTICAL INDUSTRYThe US food system and pharmaceutical industry have created an environment of convenience that is contributing to the chronic disease epidemic. Americans are eating the standard American diet—which is high in carbohydrates, sugar, factory-farmed meat, additives, and processed foods. Over the last decade, whistle-blowers in the food industry have exposed the deliberate use of food scientists to create foods that are addictive - full of added sugars, artificial colors and flavors, and specific textures that are designed to stimulate the pleasure and reward centers of the brain, similar to narcotic drugs such as cocaine (Crowe, 2013).

In his newest book, Food Fix, Dr. Mark Hyman discusses the dysfunctional and corrupt food policies and guidelines that seem to serve corporate profits over the health of Americans. Our government and our tax dollars support this unhealthy food supply by subsidizing crops such as corn, wheat and soy, which are often genetically modified and sprayed with cancer-causing pesticides. Hyman contends that modern agricultural practices which are destroying the soil, are contributing to the declining mental and physical health of Americans, and to global warming and environmental decline. “Our most powerful tool to reverse the global epidemic of chronic disease, heal the environment, reverse climate change, and poverty and social injustice, reform politics, and revive economies is food” (Hyman, 2020).

As Americans continue to eat this “diet” high in sugar and refined carbohydrates, artificial colors and flavors, and dangerous chemicals, they’re more likely to suffer from chronic diseases. Then they go to their doctor and are prescribed diabetes medication, usually metformin. At their follow-up appointment six months later, their HbA1c (Hemoglobin A1c), a three-month blood sugar average, may actually be higher as their body stops responding to the drug. The doctor tries a different drug, and the cycle continues.

But what about insulin? Unfortunately, for people with insulin resistance, injecting large amounts of insulin into the body may only make the underlying problems worse. It’s a cycle of sickness.

Diabetes by the Numbers

Diabetes cost the U.S. $327 billion each year.

$327B

Each year, 1.3 million Americans are diagnosed with diabetes.

1.3M

Americans have pre-diabetes.

88M

CDC 2017

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THE RISK OF DRUGSThe conventional-medicine go-to is a pill. While drugs are an essential part of treatment for many patients, they don’t address the environmental factors and causes of disease. For example, Huff (2014) found that patients with diabetes had a deficiency or accumulation of some essential trace elements, such as arsenic or mercury, in comparison with normal levels in nondiabetic subjects.

Insurance is no longer paying for all the testing patients need to dig deep and find out what is really happening. So patients are prescribed the quick-fix of a pill, which may lower their HbA1c, but which may also lead to increased side effects and complications.

Many researchers have found evidence that diabetes medications may cause serious harm. For example, Garratt et al, (1999) found that sulfonylureas (e.g., glipizide, glimeperide, or glyburide) —a group of medicines that increase the release of insulin from the pancreas—are “associated with an increased risk of in-hospital mortality among diabetic patients undergoing coronary angioplasty for acute myocardial infarction.” Another study concluded that rosiglitazone—a drug that makes cells more responsive to insulin—is “associated with a significant increase in the risk of myocardial infarction and with an increase in the risk of death from cardiovascular causes.” (Nissen & Wolski, 2007).

Insulin administered as a treatment has serious potential effects, as well. Hribel (2013) in The Journal of Clinical Endocrinology and Metabolism and Nandish (2011) in Current Atherosclerosis Reports reported the following:

• It more than doubles the risk of death.• It almost doubles the risk of myocardial infarction.• It more than doubles the risk of neuropathy.• In patients taking insulin, there is a 43 percent increased risk of stroke and cancer.• It more than triples the risk of renal complications.• It can lead to Diabetes Type 3 (i.e, Alzheimer’s Disease)• It can lead to compromised “vascular integrity, which may further potentiates [sic] cardiovascular morbidity and mortality.”

Two statistics are telling when placed side by side: Approximately 50 percent of Americans are taking at least one prescription drug. Six in 10 American adults have a chronic disease, and four in 10 have two or more. Clearly, our use of prescription drugs isn’t having the outcome we would hope for. (CDC, 2020).

Conventional medicine’s solution for diabetes, thyroid disorders, and other chronic diseases leaves patients wanting more accurate information and deeper testing, but they have limited options in the traditional model. The real problem is that each patient is unique and what may be causing one person’s diabetes, may differ from the next. Generally, looking for the root cause of each patient’s diabetic condition is not the objective of the traditional medical model.

THE RIGHT GOALFunctional medicine offers a different solution to these problems. The holistic approach of functional medicine seeks to get to the root cause of disease for each person to find out why he or she is sick and develop a customized program based on the individual’s biological needs.

PATIENT EDUCATION SERIESA TRUE SOLUTION FOR TYPE 2 DIABETES

There is evidence that diabetes medications, including insulin, can cause serious harm and side effects.

The holistic approach of functional medicine seeks to get to the root cause of disease for each person to find out why he or she is sick and develop a customized program based on the individual’s biological needs.

60 Percent Of Amerians Have A Chronic Disease & 50 Percent Are Taking At Least

One Prescritpion Medication.CDC 2020

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Is Reversing Your Diabetes Possible?Some of the major differences between functional medicine and conventional medicine

include the following:• Conventional medicine is disease-oriented; functional medicine is health-oriented.• Conventional medicine aims to detect disease early on; functional medicine aims to prevent disease.• Conventional medicine makes diagnoses based on symptoms; functional medicine looks at the underlying cause of disease.• Conventional medicine is specialized; functional medicine is holistic (i.e., considering the whole person rather than dividing the body into parts).

Research shows that functional medicine works. A study by Beidelschies (2019) compared 1,595 participants being treated at a functional medicine center and 5,657 being treated at a family health center. The study found that the “functional medicine patients exhibited significantly larger improvements in Patient-Reported Outcome Measurement Information System Global Physical Health at 6 months than propensity-matched patients at a family health center.”

Another study by McKenzie et al (2019) found “that an individualized program . . . that incorporates nutritional ketosis can be highly effective in improving glycemic control and weight loss in adults with [type 2 diabetes] while significantly decreasing medication use.”

Studies like these are encouraging, as are the patient experiences at Next Advanced Medicine. With more evidence mounting daily about the viability of functional medicine for chronic disease, and the risk factors associated with the pharmaceutical approach coming into view, it is their hope to contribute to the literature by analyzing and reporting patient outcomes.

The mission of Next Advanced Medicine is to reverse the disease in patients. That mission is not only possible: It is happening every day.

HOW NEXT ADVANCED MEDICINE CHANGES LIVESNext Advanced Medicine is dedicated to the practice of functional and physical medicine. While drugs are an essential part of treatment for a number of illnesses, they are not a permanent solution. Dr. Neil Hersh, MD, and Dr. Candice Hall, DC, and the committed staff at Next Advanced Medicine provide an alternative approach to patients who continually suffer from degenerative and chronic health issues.

Next Advanced Medicine takes pride in providing patients and the general community with the latest research and resources in functional medicine, addressing chronic illness, and reversing diabetes. The interdisciplinary team of medical doctors, naturopaths, chiropractors, and nutrition scientists is dedicated to providing each patient with the knowledge and support he or she needs to thrive and live a healthy lifestyle.

With patients with type 2 diabetes, the goal is to reverse the diabetes with a unique approach and get patients off their large quantities and heavy doses of medication. Next Advanced Medicine looks for long-term solutions that dive deep into the root causes and produce visible, sustainable changes in quality of life. Then, each patient receives a long-term health care plan designed specifically for his or her individual needs.

Learn How Next Advanced

Medicine Is Changing Lives

REDUCED A1C

97%

REDUCED OR ELIMINATED MEDICATIONS

93%

REVERSED HBA1C BELOW

DIABETIC RANGE (6.5)

80%

A TRUE SOLUTION FOR TYPE 2 DIABETES • NEXT ADVANCED MEDICINE WWW.NEXTADVANCEDMEDICINE.COM • DIABETES HOTLINE (888) 99-TYPE2 76

Each patient is unique, so each care plan is individualized to his or her particular needs. Here is an overview of the process:

1. A thorough patient history, looking at blood work, traumas, infections, family illness, and environmental factors.2. In-depth and rigorous testing, including the following tests:

• Stool tests to examine gut health, infections, or parasites. Treating long-standing infections is essential to reversing diabetes. • Food sensitivity testing to show what specific foods patients make antibodies to and should not eat. When people make antibodies to certain foods, their body thinks it’s an infection, which can drive inflammation and blood sugar spikes. • Hormone testing to ascertain if there are imbalances that may be contributing to the diabetes and the symptoms. • In-depth blood testing to look at over 225 markers, a full panel. This testing shows vitamin deficiency, infection, metabolic risk factors, and metabolic functioning.• Bio-toxins, and heavy metals testing to show any presence of mercury, Lyme, mold, and other toxins that can contribute to diabetes, autoimmunity, cognitive decline, and biotoxin illness.• Environmental toxin testing, including air pollution and pesticides found in our food supply.

3. Many patients go through a detoxification process and take an education course on how to eat more healthfully, including a grocery store tour, so they know the specific foods and brands that are appropriate.4. Test results then reveal which foods patients should avoid; which bacteria, viruses, or biotoxins may need to be addressed; and what environmental pollutants may be impeding proper cellular function. This information is turned into a personalized plan with diet, exercise, and nutritional support.5. Patients complete a minimum six-month program, and many choose to see us from time to time to keep an eye on their overall health (i.e., maintenance).

For patients that complete the program and follow the recommendations of their doctor, the majority reach the goal of reversing their diabetes to at least a prediabetic level, with many of them reversing to a nondiabetic level. In addition, a majority of patients come in taking prescription medications; by the end of the program, their HbA1c is being controlled naturally, and the prescription medications no longer need to be taken (see study results below).

STUDY ON PATIENT OUTCOMESFor many Next Advanced Medicine patients, diabetes was not a life sentence; it was temporary. It is their goal to reduce or

eliminate the use of prescription medications to control HbA1c should the patient be on these medications, and they work with each patient and their prescribing physician, to achieve this goal safely.

Dominick Gutierrez, for example, lowered his HbA1c from 8.4 to 5.4. Before he started the program, such a transformation didn’t seem possible. He had already lost two brothers to diabetes, and he feared the same fate for himself. Next Advanced Medicine helped him with a personalized plan, and he went from eating out every day to preparing his own meals.

Another patient, Raul Stamp, started with an HbA1c of 9.4 that decreased to 5.6 (non-diabetic), He had high cholesterol and blood pressure, and weighed over 280 pounds. Within five months, he had reversed his diabetes, lost 40 pounds, and had normal cholesterol and blood pressure.

Dwayne Heath lowered his HbA1c from 8.1 to 5.5 and lost 70 pounds.

“It comes down to education and treating the whole person, not through pharmaceuticals, but through what you intake into your body, and fixing those areas of your body through the use of supplements,” Heath says. “That education is the best willpower you can have. When you know what foods are causing the problems, it’s easier to give those things up and stay on the path.”

For more patient success stories, visit their YouTube channel and website. www.nextadvancedmedicine.com

METHOD AND RESULTSHbA1c and other health measures related to type 2 diabetes were recorded by the treating physician at the beginning and end of the program. The data was entered and compiled by one of the treating physicians. Data analysis and reporting was conducted by an independent contractor.

The primary health measure for the reversal of type 2 diabetes at Next Advanced Medicine is HbA1c, a three-month average of blood sugar and the indicator for diabetes/prediabetes. The goal is to reduce HbA1c below 6.5 (prediabetic) and reduce or eliminate medication if patients are on them when they start the program.

Other pre-study and post-study health measures recorded for each patient, but not reported in the current analysis, include cholesterol, triglycerides, C-reactive protein, weight, and homocysteine.

PATIENT EDUCATION SERIESA TRUE SOLUTION FOR TYPE 2 DIABETES

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Diabetes Reversal Outcomes for 194 Patients:

Diabetes Reversal OutcomeAll Patients in Analysis (2017)

Finish HbA1c <6.5 (prediabetic & nondiabetic reversed <6.5 or <5.7, respectively)Finish Prediabetic HbA1c 5.7–6.4

Finish Nondiabetic HbA1c <5.7Finished with Improved HbA1c

Finished with No Improvement to HbA1c

N1941568868335

%100%80%45%35%17%3%

Medication Reduction by Diabetes Reversal Outcome Subgroup:

Patients by Reversal OutcomeAll Patients in Analysis (2017)

80% Finish (prediabetic and nondiabetic) HbA1c <6.5 45% Finish Prediabetic HbA1c 5.7–6.4 (Note: This is a sub of 80% above.)35% Finish Nondiabetic HbA1c <5.7 (Note: This is a sub of 80% above.)17% Finish with Lower HbA1c (HbA1c reduced, not below the 6.5)3% Finish with No Improvement or Slight

N194

156

88

68

33

5

Started w/ Meds

177 (91%)

142 (91%)

82 (93%)

60 (88%)

28 (93%)

4 (80%)

Patients by Reversal Outcome(93%) 164 of 177 reduced or eliminated medication(s)(94%) 134 of 142 reduced or eliminated medication(s)(95%) 78 of 82reduced or eliminated medication(s)(93%) 56 of 60reduced or eliminated medication(s)(93%) or 28 of 30reduced or eliminated medication(s) (100%) or 4 of 4reduced or eliminated medication(s)

Results:How many reversed their diabetes? How much did the program change their HbA1c? At the end of the program (approximately six months), the following results were recorded:

97%80%

17%

3%

• 97% of patients (N=189) had reduced their HbA1c, on average by 1.8, and 93% reduced or eliminated medications. Note that 91% of the sample started on medications.

• 80% of patients (N=156) had HbA1cs in the nondiabetic (N=68 or 35% of the patients) and prediabetic (N=88 or 45% of the patients). Of the patients in the nondiabetic range and in the prediabetic range, 93% were on medication to start, and 95% reduced or eliminated medication while reducing their HbA1cs.

• 17% of patients (N=33) had HbA1c reductions that ranged from .1 to 5.6 (average of 2.0). 93% or 28 of 30 also reduced/eliminated medications. (Three were not on medication.)

• 3% of patients (N=5) did not see improved HbA1c. However, 4/4 (100%) reduced and eliminated medications. (One was not on medication.) Also, three of these individuals ended below a 6.5 (prediabetic), so outcomes are partially favorable for all patients, with mitigating factors for why HbA1c might increase.

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CONCLUSION AND RECOMMENDATIONSDiabetes is considered to be a chronic, degenerative disease. We know that the primary treatment for diabetes is prescription medications and although helpful they are admittedly intended to manage the progression, not reverse the condition, and can have major side effects including worsening of the diabetes and its complications over time.

The food system is broken—and they are subsidizing the production of foods that are making us sick, such as corn, wheat, factory-farmed meat, soy, and others. In addition, our food supply is tainted with a growing number of cancer-causing pesticides, additives, and addictive substances. Evidence suggests that these food policies and our resulting food system are largely responsible for the exploding number of chronic diseases such as diabetes, yet it is still one of many possible causes affecting each individual.

Next Advanced Medicine, acknowledge that many factors lead to the development of diabetes, including trauma, infections, toxic exposures, processed foods and the standard American diet, stress, genetic predispositions, and hormonal imbalances, just to name a few, so their approach looks at and addresses all of these contributing factors.

What Next Advanced Medicine does really works. They reverse chronic disease for hundreds of patients each year by treating patients at the cellular level, looking at the cause for disease, and naturally supporting the body to return to health.

They believe in a functional medicine approach to chronic disease. The mission of Next Advanced Medicine is to restore the hope and health of all they serve by providing life-saving strategies specific to individuals and empowering them to make the necessary changes to reclaim their health.

While they can’t help everyone, they work diligently to effectively help as many people as they can. They offer free webinars, which is a great place to start. Visit www.nextadvancedmedicine.com/seminars-overview/ for more information.

Recommendations:• Consider working with a functional medicine practitioner to see if the approach is right for you. Work with your healthcare provider to test for the causes of chronic illness. Ask for extensive blood work, stool testing, hormone testing, and food sensitivity. Ask them to dig deeper so you can get to the causes of your health issues.

• Question the pharmaceuticals recommended to you and the side effects. What are the short-term alternatives and long-term risks of taking them? Will you need to take it forever? Are there lifestyle

PATIENT EDUCATION SERIESA TRUE SOLUTION FOR TYPE 2 DIABETES

changes you can make to lower your blood sugar and achieve the same result (e.g., altering your diet or toxic exposure to reduce blood sugar spikes naturally)?

• While each individual’s nutritional needs are unique, there are some basic principles to consider. Be conscious of what you eat, and choose whole, organic, and fresh foods whenever possible. It’s not about the quantity of food, but the quality. Avoid processed foods, refined carbs and sugar, gluten, dairy, soy, GMOs, and hydrogenated oils. We have some great recipes on our website! Visit nextadvancedmedicine.com/category/recipes/.

• Avoid toxins going into your body by selecting the right self-care products and educating yourself on lifestyle improvements that will improve your health. Many common products such as shampoo, body wash, household cleaners, and even toothpaste contain toxins and hormone disruptors that challenge your health on a daily basis.

• Seek out holistic approaches to achieving health. Next Advanced Medicine will continue analyzing and sharing patient outcomes to encourage those struggling with a chronic disease that they can truly turn around.

LEARN FROM HOME! Attend a Free Webinarwww.nextadvancedmedicine.com/seminars-overview/ To Contact Next Advanced Medicine:Next Advanced Medicine1422 Edinger, Suite 130Tustin, CA 92780(888) 99-TYPE2

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When you choose doctors who value their patients as individuals, you’ll start finding real answers and lasting solutions. Whether you suffer from diabetes, thyroid disease, autoimmune disease, or any number of other chronic and degenerative disorders, Next Advanced Medicine is dedicated to healing your physical condition and restoring your health. They are an interdisciplinary medical practice in Orange County, Calif., that focuses on healing disease, not treating symptoms. Their team of medical doctors, chiropractors, naturopaths, and nutrition scientists focuses on treating the whole patient; they consider the complex confluence of genetic, environmental, and lifestyle factors that affects disease progression and treatment. No matter what type of chronic or degenerative symptoms you’re facing, Next Advanced Medicine can help you gain full control of your symptoms and develop customized, achievable lifestyle changes.

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TRUST THE LEADERS IN FUNCTIONAL MEDICINE

REFERENCES (IN ORDER OF APPEARANCE):1. Center for Disease Control and Prevention (CDC) (2020). National Diabetes Statistics Report: Estimates of Diabetes and it’s Burden in the United States 2020. Retrieved from: https://www.cdc.gov/diabetes/pdfs/data/statistics/national-diabetes-statistics-report.pdf2. Center for Disease and Prevention (CDC) National Center for Health Statistics (NCHS) (2017). Prevalence of Obesity Among Adults and Youth: United States, 2015–2016. Data Brief (#288). Retrieved from: https://www.cdc.gov/nchs/data/databriefs/db288.pdf3. Center for Disease Control and Prevention (CDC, 2020). National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP). Chronic Diseases in America Infographic. Retrieved from. https://www.cdc.gov/chronicdisease/pdf/infographics/chronic-disease-H.pdf4. Center for Disease Control and Prevention (CDC, 2020). National Center for Chronic Disease Prevention and Health Promotion. NCCDPHP At A Glance. Retrieved from: https://www.cdc.gov/chronicdisease/pdf/aag/nccdphp-aag-508.pdf5. Diabetes Services (2020). Type 2 Diabetes: Symptoms and Causes. Retrieved from: https://www.diabetesnet.com/about-diabetes/types-diabetes/type-2/6. Krowe, C. (2013, March 6). Food Cravings Engineered by Industry. CBC News. Retrieved from: https://www.cbc.ca/news/health/food-cravings-engineered-by-industry-1.13952257. Hyman, Mark M.D. Food Fix: How to save our heath, our economy, our communities, and our planet- one bite at a time (2020). Little, Brown Spark. Available: https://foodfixbook.com/8. Huff, E.A. (2014, April 24). Heavy Metals Scientifically Linked to Causing Diabetes. Natural News. Retrieved from: htps://naturalnews.com/044852_heavy_metals_.diabetes_trace_elements.html9. Garratt, K.N. et al (1999). Sulfonylurea Drugs Increase Early Mortality in Patients with Diabetes Mellitus After Direct Angioplasty for Acute Myocardial Infarction. Journal of American College of

Cardiology, 33(1):119-24. Retrieved from: https://pubmed.ncbi.nlm.nih.gov/9935017/10. Nissen, S.E., M.D., & Wolsky, K. (2007, Jun 14). Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes. New England Journal of Medicine, (356) 2457-2471. Retrieved from: https://www.nejm.org/doi/full/10.1056/NEJMoa07276111. Hribal, M. L. et al. (2013, Feb 1). Insulin-Like Growth Factor-I, Inflammatory Proteins, and Fibrosis in Subjects with Nonalcoholic Fatty Liver Disease. The Journal of Clinical Endocrinology & Metabolism, Vol 98(2), pp E304–E308. Retrieved from: https://academic.oup.com/jcem/article/98/2/E304/283372912. Nandish, et al (2011). Vasculotoxic Effects Of Insulin And Its Role In Atherosclerosis: What Is The Evidence? Current Astherosclerosis,13(2):123-128. Retrieved from: https://pubmed.ncbi.nlm.nih.gov/21287301/13. Beidelschies, M., PhD., et al (2019). Association of the Functional Medicine Model of Care with Patient-Reported Health-Related Quality-of-Life Outcomes. JAMA Network Open. Retrieved from: https://thedr.com/PDFs/beidelschies_2019_oi_190534.pdf14. McKenzie AL, Hallberg SJ, Creighton BC, Volk BM, Link TM, Abner MK, Glon RM, McCarter JP, Volek JS, Phinney SD. A Novel Intervention Including Individualized Nutritional Recommendations Reduces Hemoglobin A1c Level, Medication Use, and Weight in Type 2 Diabetes. JMIR Diabetes, ;2(1) :e5. Retrieved from: https://diabetes.jmir.org/2017/1/e5/15. Avena, N.M., Rava, P., and Hoebel, B.G. (2008). Evidence for Sugar Addiction: Behavioral and Neurochemical Effects of Intermittent, Excessive Sugar Intake. Neuroscience and Behavioral Reviews, 32(1), 20-39. Retrieved from:https://www.sciencedirect.com/science/article/abs/pii/S3407000589