Company Profile

DATE CONTENTS

1999. 08 Company Founded

1999.10 Registered as Venture Company

2000. 03 Development of Infrared Thermography, Model IRIS-5000

2001. 06 Obtained CE Marking and EN46001

2001.12 Development of Stress Analyzer, Model SA-3000P

2003. 10 Built the world first Oriental HRV reference

2005. 09 Patent of HRV in Japan

2006. 03 Development of IRIS-XP with CCD Type

2006. 07 Established for Medicore Japan

2007. 02 Approval of KGMP

2007. 03 Development of BodyChecker

2007. 04 Development of DICAN

2007. 12 Approval of FDA for SA-3000P in USA

COMPANY HISTORY

DATE CONTENTS

2008. 05 Completion of NEW APG Algorithm

2009. 03 Development of Max Pulse

2009. 08 10th Anniversary of the Establishment

2010. 11 Obtained CE-MDD for DiCAN

2011. 02 Obtained CE-MDD for IRIS-XP

2011. 07 FDA Approval for Max Pulse

2012. 01 Launched Smart Pulse

2012. 03 Obtained CFDA Approval for BodyChecker

2013. 05 Contract with G-Tech International in China

2013. 08 KFDA Approval for IRIS-8000

2013. 10 Long-term Agreement with OSIM International in Singapore

2014. 01 Moved to the New Factory

2014. 03 New Release of AFT-800 & IRIS-8000

2014. 05 Acquisition of CFDA approval of Smart Pulse in China

COMPANY HISTORY

DISTRIBUTORS LOCATION AROUND THE WORLD

USA Japan China Taiwan Indonesia

Brazil Sweden Singapore Thailand Philippines

FDA : SA-3000P, Max Pulse CE : IRIS-XP, IRIS-5000, SA-3000P Bodychecker, Max Pulse, DiCAN, Smart Pulse SFDA : IRIS-5000, SA-3000P, Smart Pulse Patent : Thermography, Heart Rate Variability

OBTAINED CERTIFICATES

Ref Item Date(y-m-d) Article

Reg Patent 2005-04-15 BGA Socket Test System

Reg Patent 2005-05-16 Apparatus of infrared imaging device with infrared detector

Reg Patent 2005-07-01 IR data compensating method of in-circuit test system

Reg Patent 2005-08-26 Optic apparatus of vision system for circuit board testing

Reg Patent 2005-09-29 IR In Circuit Test System

Reg Matent 2005-10-19 Fixture for circuit board testing

Reg Patent 2006-09-29 Universal Fixture for circuit board testing

Reg Patent 2012-08-10 Circuit board testing and its testing method

Intellectual Property Right

Ref Item Date(y-m-d) Article

Reg Practical 2000-09-18 Light apparatus for medical use

Reg Design 2001-01-30 Infrared Thermography

Reg Practical 2001-03-31 Therapeutic device for disk

Reg Design 2002-04-12 Light stimulator for medical use

Reg Patient 2003-09-18 Control method of infrared thermography

Reg Patent 2004-10-14 Light stimulating apparatus for medical use

Reg Patent 2005-05-26 ANS function test device

Reg Patent 2009-01-05 ANS function test device(Japan)

Reg Patent 2011-01-06 Thermal imaging system and its method

Reg Patent 2011-07-29 Cardiovascular ANS test device for diabetic neuropathy

Reg Design 2013-11-07 Medical display terminal with image design and other 10 items

Infrared Technique Bio-Signal System

IRIS-5000 IRIS-XP

Pain management SA-3000P BodyChecker Max Pulse Smart Pulse DiCAN

PRODUCT LINES

MAX PULSE BODY CHECKER

Smart Pulse(C type)

SA-3000P

Smart Pulse(B type) Smart Pulse(A type)

IRIS-8000

AFT-800 DICAN

IRIS-XP

SMART PULSE

Innovative Solution To Check your Stress Level & Arterial Health

Part 1 . Smart Pulse ? Part 2 . Market Prospect Part 3 . Background Theory Part 4 . Test Result Analysis RSA Training Cautions for measurement

Part 1 . Smart Pulse ?

Part 1. Smart Pulse ? 1) What’s the Smart Pulse?

Smart Pulse

Portable Easy

Stress Analyzer

Arterial Health

U-Health Care

Part 1. Smart Pulse ? 2) Main Functions

1. Stress Measurement - Physical / Mental Stress - Stress Resistance

2. Arterial Health Measurement - Level of Arterial Health - Blood Circulation & Vessel Condition

3. Cumulative Test - Enable to have the continuous management

4. Breath Training (RSA Training) - Improve the ANS Function - Control Stress

Part 1. Smart Pulse ? 3) The Types

PC (Window O/S) O PC (Window O/S) O PC (Window O/S) OAndroid Smart Phone & Tablet O Android Smart Phone & Tablet O Android Smart Phone & Tablet O

iPhone & iPad X iPhone & iPad X iPhone & iPad OUSB Cable O USB Cable O USB Cable OBluetooth X Bluetooth X Bluetooth O

Self Measurement Function X Self Measurement Function O Self Measurement Function O

Display X Display O Display O

C type B type A type

Part 1. Smart Pulse ? 4) Strengths

• Operation with ONE button • Compact Size • Easy Test Report • Support 5 Languages

Usability

• Support both USB Cable & Bluetooth • Android Smart Phone & Tablet PC • iPhone & iPad • Window O/S PC

Compatible

• Build Own Clinical Reference ( More than 12,000 cases )

• CE, SFDA, MHLW, KFDA approved

Reliability

Part 1. Smart Pulse ? 5) Why it’s Smart ?

Smart Use Smart Diagnosis

Part 1. Smart Pulse ? 6) Usable Area

Total Solution U-Health Care

Stress Assessment

ANS Function

Predictor of Cardiovascular

Disease

Blood Vessel & Circulation

Disease prevention &

Proper Management

by SMART PULSE

7) Who need Smart Pulse?

Who have ~ Chronic fatigue

Excessive stress Cardiovascular Disease

Headache / Migraine

Obesity

Adult diseases

Inertia, drowsy

Failure of

the concentration & memory

Part 1. Smart Pulse ?

Part 1. Smart Pulse ? 8-1) Reliability of Smart Pulse

< ASIAN Reference Research > 1. Clinical Research in 8 main hospitals in Korea - Busan University Hospital - Donga University Hospital - Inje University Hospital - Eulji University Hospital - Ewha University Hospital - Dankuk University Hospital - Gacheon University Hospital - Hallim University Hospital

2. Clinical research for 2 years (from May 2001 to June 2003) 3. Acquired more than 12,000 cases for the normal people 4. Built ASIAN reference for the 1st in the world 5. There are big difference of normal range between western and

asian people

Part 1. Smart Pulse ? 8-2) Reliability of Smart Pulse

Only Smart Pulse provides both ASIAN & Western Reference

Part 1. Smart Pulse ? 8-3) Reliability of Smart Pulse

Patent in Korea Patent in Japan

Part 1. Smart Pulse ? 9) Certificates

[ CE in Europe ] [ CFDA in China ] [ MHLW in Japan ]

Part 2 . Market Prospect

1) Stress Part 2. Market Prospect

ANS Disorder

Disease

Pressure

Stress

2) Effects of Stress on the Body Part 2. Market Prospect

3) Cardiovascular Disease Part 2. Market Prospect

17.1 million people die from Cardiovascular Disease every year

Part 2. Market Prospect 4) U-Health Care Market

U-Health Care Market has Great Potential !

Change in concept of modern medical science Issue(U-health)

• Should not have any limit

from time and location

• Simple to use

• Need the Feedback &

DB Management

(Connect to the Network)

• Treatment of Disease • Focus in Disease

Diabetes, Cardiovascular Disease

Hypertension, Obesity Depression, Anxiety Disorders

• Prevention of Disease • Focus in“Quality of Life”

5) Market Situation Part 2. Market Prospect

Stress

Highly

Increased Stress-related

Problems

Cardiovascular Disease

Increased

Risk of Death

U-health Care

Great Potential

in U-health Care Market.

High Demand of New & Innovative Health-Care Device

6) Total Solution of Market Demands Part 2. Market Prospect

Smart Pulse

Analyze & Control Stress

Prevention & Management

ANS dysfunction Disease

The KEY of U-Health Care

Business

Predict Cardiovascular

Disease &

Check-Up Vascular Health

7) Target Markets Part 2. Market Prospect

- Health Food & Vitamin/Dietary Supplements Company - Adult disease or Cardiovascular Disease management (Hypertension, Diabetes, Arteriosclerosis) - Drugstore Chain, Superstore, Department store - U Healthcare market - Online Market ( Amazon, Ebay, Taobao )

- Fitness Center, Sports Center, Beauty shop, Spa, Massage shop - Stock exchange hall, Educational institutes, Subway driver - Airlines, Police Station, Fire Station, Military, Bank

8) Main Applications Part 2. Market Prospect

• Work stress, Chronic Stress, Insomnia, Depression 1. Office Workers

• Study stress, Low concentration, Mental instability, Addiction to Internet

2.Pediatrics/ Teenagers

• Depression, Loneliness, Conflict, Blood circulation & Cardiovascular disorder 3. Seniors

• Management of stress and depression before and after childbirth 4. Maternity

• Continuous monitoring on promotion of health 5. Fitness/Beauty/

Dietary Supplement

9) Dietary Supplements Company Part 2. Market Prospect

Continuous Health Monitoring service for

Product Promotion

Compare before & after taking Supplements

10) Disease management Part 2. Market Prospect

Precaution Management of Blood Vessel Health,

Cardiovascular Diseases & Adult Diseases

11) Drugstore Chain, Superstore Part 2. Market Prospect

Free Check-up Health at Drugstore or Superstore

= Promote Purchase of related products

12) Online Market Part 2. Market Prospect

Enter the Online Market

= Promote to average consumers & Maximize marketing opportunities

13) Fitness/Beauty & Aromatherapy Part 2. Market Prospect

Systematic Health Management &

Differentiated Service

=Growth in Membership

14) Company Part 2. Market Prospect

Efficient Management of Work Stress & Chronic Fatigue

= Improve Welfare for employees

15) Military & Police/Fire Station Part 2. Market Prospect

Check-up & Management of

P.T.S.D

Part 3 . Background Theory

1) Background Theory Part 3. Background Theory

1. Stress assessment 2. Assessment of ANS function 3. Predictor of cardiovascular disorder 4. Arteriosclerosis / Peripheral circulation

Autonomic Nervous System

HRV theory

Peripheral Blood Circulation

APG theory

2) What’s the HRV Part 3. Background Theory

ECG SIGNAL

845 → 745 → 812 → 732

Autonomic Nervous System which affects the sinoatrial node, is

changed every moment by internal or external environment.

HRV, heart rate variability is the degree of fluctuation

in the time intervals between heart beats.

3) ANS Part 3. Background Theory

ANS- Autonomic Nervous System Main Function : Maintaining the Homeostasis as a control system of our internal organs Branch : SNS (Sympathetic Nervous System) & PNS (Parasympathetic Nervous System) Acts : heart rate control including hormonal, enzymatic, respiratory, pulmonary, urinary and uterine neural control Diseases related to ANS dysfunction →Diabetes, Hypertension, Irritable Bowel Syndrome, Headache, Sudden Death after MI, Depression, Anxiety, Sleep disorder

4) The Diagram of HRV Part 3. Background Theory

Internal disturbance

Emotional Effect Thermo-regulation Body Posture(BP)

Illumination etc......

ANS Disorder Cardiovascular Diseases

Neuropathy Stress / Aging

etc.....

Autonomic Nervous System

S Cardiac

Inherent Rhythm (SA node)

Fluctuation of

Heart Rate

5) Correlation between ANS & HRV Part 3. Background Theory

Lowered complexity of heart beats = Low Level of HRV

Improper ANS function

Weakened coping ability with constant environmental changes

Easily breakable homeostasis

6) Correlation Diagram Part 3. Background Theory

Stress

Disease

ANS Function Health

Break Treatment

Maintain Homeostasis

HRV HRV

Proper ANS Function lead to bigger fluctuation of HR

7) HRV clinical application Part 3. Background Theory

HRV is the Most Reliable Index & Window to the Autonomic Nervous System. More than 18,000 papers on the PubMed !!

8) PTG – the base waveform of APG Part 3. Background Theory

Plethysmograph (PTG) The wave form signal that indicates pulsation of chest wall and

great arteries followed by heart beat.

-> Changes the aortic pressure

-> Transmit the pressure change to the peripheral nerve

(transmission time to the finger tip : 0.16sec)

9) What’s the APG Part 3. Background Theory

The Final Analysis Waveform – APG

Plethysmogram(PTG) - basic wave Velocity Plethysmogram(VPG)

Acceleration Plethysmogram(APG)

- To stabilize the baseline - To make more clearly

1st

diff

2nd diff

10) APG Waveform Part 3. Background Theory

a

b

c

d

• a : Basic point to evaluate APG waveform • b：Cardiac constriction power (Cardiac output)

– The deeper (–) value is better shape

• c：Arterial Elasticity – Higher (+) value is better

• d： Remaining blood volume – Higher value, smaller (-) value is better

* The gradient of b, d point

: Vascular state and Blood Vessel Aging degree

11) Level of Blood Vessel Part 3. Background Theory

7 levels by the vascular

state

Classifying the wave type as aging

Level 1 : Blood circulation and its vessel are Excellent

Level 2 : Blood circulation and its vessel are Good

Level 3~4 : Start to get aged in the vessel

Level 5 : Not good at the blood circulation and aged state in the vessel

Level 6~7 : Blood circulation Disorder

12) Correlation to the Artery

Normal Blood Vessel Abnormal Blood Vessel

This vessel is located at Level 1 and no any plague around the vessel.

This vessel has a lot of plague and vessel stiffness is also thick so it is located at Level 5~6.

APG is the solution to check your Blood Vessel & Circulation condition.

Part 3. Background Theory

13) APG Clinical Application

Level 6 Level 3

Level 3 Level 5

Pneumonia

Diabetes

Pre-treatment Post-treatment

Part 3. Background Theory

Part 4 . Test Result Analysis

1) Test Result Screen

PC Smart Phone

Part 4. Test Result Analysis

2) Heart Rate Analysis

Mean Heart Rate: It means the number of heart beats running at every minute on average. Adult people have generally 60~90 heart beats per minute, but it can be different from the age. Those who do a lot of exercise everyday will be under 60 beats per minute for the mean heart rate. However, those who have a lot of stress will be over 90 beats per minute for the mean heart rate. Ectopic Beat : During the measurement, in case of moving up and down severely or having arrhythmia, it will be appeared the abnormal heart rate irregularly. If the ectopic beat is over 5 times for 3 minutes, the person may have arrhythmia or moved too much. Therefore, it is recommended to measure the test again in that case. Although the test seems to be measured correctly, if the ectopic beats appear many times over 5, it seems to be arrhythmia.

Part 4. Test Result Analysis

3-1) Stress Analysis

Waveform of HRV ( Heart Rate Variability ) It is describing the change of heart beat with the graph at real time and the bigger the change of variable heart rate, the healthier it is, the better the stress resistance is and the better autonomic nerve system is also. Autonomic Nerve Balance PNS Dominant: If parasympathetic nerve is excessively dominant, it means that the person has depression or can’t be bothering anything or loses the motivation. Balance: It means that sympathetic nerve and parasympathetic nerve are properly balanced each other. In general, ratio of SNS and PNS is 6:4, 5:5, 4:6 and it means the balance of autonomic nerve system. SNS Dominant: If sympathetic nerve is excessively high, it means that the person has anxiety, irritation, and excessive nervousness. In other words, if the person has excitation or stress severely and has sleep disorder, aggressive character, agitation and overheating on body, it is highly dominant.

Part 4. Test Result Analysis

3-2) Stress Analysis

Physical Stress It means the status of how much gets stress physically. Mental Stress It means that the status of how much gets stress mentally. Stress Resistance As an indicator of how much we are accustomed to the stress, it will be greatly resistant to the stress in the healthy people under the same stress while it will be bad in resistance for the unhealthy people if they lose the resistant ability in body or have a weak autonomic nerve system function. Stress Score It is made by the analysis of total stress and 100 score is the worst while the lower score is the better. Green Color: Low Stress Level Yellow Color: Average in Stress Level Red Color: Excessive Stress Level

Part 4. Test Result Analysis

4-1) Arterial Health Analysis

Level of Arterial It means that the aging level of blood vessel has classified by Type 1 to Type 7 and it describes with percentage (%). Type 1 means the best blood circulation while Type 7 means the worst blood circulation.

Level Analysis by waveform

Part 4. Test Result Analysis

4-2) Arterial Health Analysis Part 4. Test Result Analysis

Eccentric Constriction (Cardiac Output): It means the blood pumping power from left ventricle to aorta by the heart constriction. Arterial Elasticity: It means the arterial elasticity with vibrating waves by the elasticity of wall of blood vessel when the blood flows from the left ventricle. It will be better in a person who has healthy vessel. Remaining Blood Volume It means the blood volume remaining in the vessel without flowing to the aorta by constricting the heart from the waves appearing when the blood hits valves by closing aortic valve. *As aging of blood vessel is processing, the cardiac output is weaker and remaining a lot of volumes. Level of Arterial Health It shows which level is located out of total 7 levels of vascular health. Green color zone: level 1~2 Yellow color zone: level 3 Red color zone: level 4~7

RSA Training

1) RSA Training?

RSA (Respiratory Sinus Arrhythmia)? Respiratory sinus arrhythmia (RSA) is a naturally occurring variation in heart rate that occurs during a breathing cycle. With using this to the breath training, we can improve our Biological Rhythm. Effects of RSA Training Reducing & Controlling Stress Improving Autonomic Nerve System Function Maintaining Balanced Emotional State Improving Concentration Increasing Body Energy

2) Change of Heart Rate Pattern by Training

Post-Training Pre-Training

Small Variation of Heart Rate

Irregular HRV signal Unstable Heart Rate Pattern

Big Variation of Heart Rate Regular HRV signal Stable Heart Rate Pattern

3) How to do RSA training

1. Connect the Smart Pulse with your Smart Phone or Tablet by USB Cable or Bluetooth. ( Now, Only Android Devices support the RSA training function. )

2. Select the ‘Breathing’ menu from the Main Screen. 3. Insert your left index finger in Smart Pulse and Start the RSA Training by

selecting the ‘Start’ Button ( ). 4. Go into the Breathing Training according to the guide voice & image.

4) Training

: Training Time (2min/3min/5min)

: Training Level (Easy/Normal/Difficult)

: Start

: Breath Interval by bpm

: Setting

: Breathing Image Inspiration Turn The image becomes bigger Expiration Turn: The image becomes smaller

5) Setting

Sound : Select the effect sound

Voice : Select the voice guide language

Image : Select the breathing image

Time : Select the training time (2Min/3Min/5Min)

Grade : Select the training level (Easy/Normal/Difficult)

: : Save the Settings

: : Move to the Training Mode

6) Training Result

Training Results : The Result comes out by analyzing HRV signal during the breathing training (2min~5min).

Try Again : score below 59

Good : score 60 ~ 80

Excellent : score above 81

Cautions for measurement

Cautions for measurement

Do not move or talk during the measurement. Do not exercise and relax about 10 minutes in measuring room before taking

measurement. Do not strain and then take regular breath. Refrain slow breath during taking

measurement. Keep the height of the sensor same to the heart. The measurement should be taken with eye open. Consult with doctor in case of arrhythmia or cardiac disease. Measuring in the morning recommended Refrain from smoking, taking drug or coffee 3 hours prior to the measurement. Refrain drinking the day before taking measurement. Refrain from wearing accessories (ring, watch, manicure on a nail) that may

interfere accurate measurement. Avoid measurement after meal.

Keep quiet and comfortable conditions in the room. (room temp.22℃ ~26℃)

Thanks for your Attention !