SLEEP APNEA, CARDIOVASCULAR AND EXERCISE ...SLEEP APNEA, CARDIOVASCULAR AND EXERCISE (SAVE) STUDY...
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A CLOSER LOOK Obstructive sleep apnea (OSA) is a serious medical condition that affects an estimated 15 million US adults and is characterized by repeated episodes of upper airway obstruction, recurrent arousals and episodic oxyhemoglobin desaturations during sleep. These abnormalities contribute to subclinical alterations in vascular function that increase the risk of cardiovascular disease morbidity and mortality. In contrast, exercise confers cardioprotection through improvements in vascular health. The SAVE study is a National Institutes of Health Academic Research Enhancement Award (AREA) aimed at evaluating whether the beneficial effects of exercise on vascular function are attenuated in obese individuals suffering from untreated OSA. The project is in its second year of funding and involves collaborators from the Johns Hopkins School of Medicine and the Pulmonary and Critical Care Associates of Baltimore. The overarching goal of this project is to provide Towson University faculty and students and their healthcare partners with an appropriate springboard in the 21 st century in preparation for effective delivery of preventative care. The study is currently recruiting overweight, sedentary adults to take part in this clinical trial. SERVICES • Overnight diagnostic sleep (polysomnography) studies • Dual energy x-ray absorptiometry (dxa) studies • Central artery pressure waveform analysis and pulse wave velocity analysis • Six weeks of monitored exercise training CONTACT Devon Dobrosielski, PhD Kinesiology Phone: 410-704-5604 | Email: [email protected] Susheel Patil, MD, PhD Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine Phone: 410-704-0572 | Email: [email protected] Hyunjeong Park, PhD, MPH, MSN, ANP, RN Department of Nursing Phone: 410-704-4514 | Email: [email protected] PARTNER ORGANIZATION Pulmonary and Critical Care Associates of Baltimore www.pccab.com SLEEP APNEA, CARDIOVASCULAR AND EXERCISE (SAVE) STUDY Developing a state of the art training/research program capable of clinically relevant instruction and research excellence clinicaltrials.gov/ct2/show/NCT03219749
Transcript of SLEEP APNEA, CARDIOVASCULAR AND EXERCISE ...SLEEP APNEA, CARDIOVASCULAR AND EXERCISE (SAVE) STUDY...
A CLOSER LOOK
Obstructive sleep apnea (OSA) is a serious medical condition that affects
an estimated 15 million US adults and is characterized by repeated
episodes of upper airway obstruction, recurrent arousals and episodic
oxyhemoglobin desaturations during sleep. These abnormalities contribute
to subclinical alterations in vascular function that increase the risk of
cardiovascular disease morbidity and mortality. In contrast, exercise
confers cardioprotection through improvements in vascular health.
The SAVE study is a National Institutes of Health Academic Research
Enhancement Award (AREA) aimed at evaluating whether the beneficial
effects of exercise on vascular function are attenuated in obese individuals
suffering from untreated OSA. The project is in its second year of funding
and involves collaborators from the Johns Hopkins School of Medicine and
the Pulmonary and Critical Care Associates of Baltimore. The overarching
goal of this project is to provide Towson University faculty and students
and their healthcare partners with an appropriate springboard in the 21st
century in preparation for effective delivery of preventative care. The study
is currently recruiting overweight, sedentary adults to take part in this
clinical trial.
SERVICES
• Overnight diagnostic sleep (polysomnography) studies
• Dual energy x-ray absorptiometry (dxa) studies
• Central artery pressure waveform analysis and pulse wave velocity
analysis
• Six weeks of monitored exercise training
CONTACT Devon Dobrosielski, PhDKinesiologyPhone: 410-704-5604 | Email: [email protected]
Susheel Patil, MD, PhDPulmonary and Critical Care Medicine, Johns Hopkins School of MedicinePhone: 410-704-0572 | Email: [email protected]
Hyunjeong Park, PhD, MPH, MSN, ANP, RNDepartment of NursingPhone: 410-704-4514 | Email: [email protected]
PARTNER ORGANIZATION
Pulmonary and Critical Care Associates of Baltimorewww.pccab.com
SLEEP APNEA, CARDIOVASCULAR AND EXERCISE (SAVE) STUDYDeveloping a state of the art training/research program capable of clinically relevant instruction and research excellence
clinicaltrials.gov/ct2/show/NCT03219749
