RPE changes in OCT

Time Domain OCT Spectral Domain OCT

Spectral Domain OCT (Enhanced Depth Imaging tech)

ThicknessContourIrregularitiesFragmentation

Detachment of Bruch’s membrane.

Abnormal structures anterior or posterior to the RPE.

RPE Changes in SD-OCT

Variation Vs. Shadowing artifacts.

1. RPE band thickening

Localized thickening Occult CNVM

1. RPE band thickening

Localized thickening Proliferation at edges of atrophy

2. RPE band thinning

Localized or diffuse thinning Atrophy

3. RPE discontinuity

RPE tear and retraction CNVM

Shadowing or masking Hge, intraretinal deposits, Blood vessels

4. RPE elevation

Drusen

4. RPE elevation

Drusen- large or confluent “Drusenoid RPE detachment”

4. RPE elevation

Drusen- large or confluent “Drusenoid RPE detachment”

4. RPE elevation

Drusen Reticular Drusen or pseudodrusen

“Subretinal drusenoid deposits”

4. RPE elevation

Drusen Reticular Drusen or pseudodrusen

“Subretinal drusenoid deposits”

4. RPE elevation

RPE Detachment • Serous• Fibrovascular• Hgic

4. RPE elevation

RPE Detachment • SerousOccult CNVM

4. RPE elevation

RPE Detachment • SerousOccult CNVM

4. RPE elevation

RPE Detachment • Serous CSCR

4. RPE elevation

RPE Detachment • Serous CSCR

4. RPE elevation

RPE Detachment • Hgic, Vascular and Fibrovascular

4. RPE elevation

5. Abnormal deposits

Vitelliform material Best disease

Vitelliform material Adult type

Inflammatory deposits APMPPE

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RPE changes in OCT

Health & Medicine

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