The Semantics of Drug Discovery and Marketing:

How to Empower Knowledge Workers and Save Money

Rob GonzalezSenior Product ManagerCambridge Semantics Inc.rob@cambridgesemantics.com

1945

In 2002, out of 89 new drugs, no new antibiotics were approved.

1945TODAY

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The Easy Problems have been Solved

The Environment is Becoming more Complex

New Technologies are being Introduced at an Increasing Rate

There is a Deluge of Data

The Price of Innovation

R&D Expenses Increase 7.4%/year faster than general inflation

In Every Phase of a Drug’s Life

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"No plan of battle ever survives contact with the enemy.”

- Heinz Guderian

“The only constant is change.”

-Herakleitos of Ephesus, cerca 500 B.C.E.

“This too shall pass.”

-Proverb

Traditional IT

Flexibility in the face of Changing Requirements

In business, new situations arise that require previously unknown data from unanticipated sources presented in unexpected ways to end users.

Case Studies:

1. Assay Management in Drug Research

2. Manufacturing Quality Control

3. Salesforce Optimization

Manufacturing Quality Control

Pharma Manufacturing at 50,000 ft.

What happens when a defect occurs?

??

This Process Took Weeks!!!

?

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The World Changes

Traditionally:

Change is costly

Semantics:

Change is cheap(from Lee)

Benefits

1. Can evolve very rapidly.

2. Can be used by end users (scientists).

The Semantics of Spreadsheets

To use a Spreadsheet to solve a Problem

1. Open Excel

2. Type Stuff In

Cambridge Semantics Anzo Middleware Platform

℠

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Anzo Data Collaboration Server

Anzo SolutionProvides Scientists:

• Sub-hour turnaround for root cause analysis (vs. WEEKS before!)

• Familiar day-to-day tools (Excel for data entry, Web for analysis)

Provides IT:

• Rapid Solution to Integration Problem (1 week initial implementation)

• Full audit trail for compliance

• Low Capex

• Access control and governance over sensitive data

Linking is a Semantic Mapping of Spreadsheet Data to a standard model

Salesforce Optimization

Pharma Sales is Collaborative

Situation:

•Market position of leading drug is threatened by new entrants

•Each of 100+ reps has hundredsof Drs. in his territory

•Whom should each speak with today? This week? This month?

•Heuristic requires two-way data communication. Data in heuristic likely to change

•Existing data collaboration was done via spreadsheets

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Pharma Sales is Collaborative

Pharma Sales is Collaborative

Anzo Data Collaboration Server

Provides Reps:

• Optimal lead identification

• Familiar tools with zero training required

Provides Sales Management:

• Ability to protect holistic market position

• Ability to go on offensive in specific regions

• More accurate sales forecasting (the reps actually use the CRM!)

• Ability to change heuristic without requiring IT intervention

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The Easy Problems have been Solved

The Environment is Becoming more Complex

New Technologies are being Introduced at an Increasing Rate

There is a Deluge of Data

Semantic Technologies Handle this through:

– Flexibility in the Face of Inevitable Change

– Focusing on End Users

– Providing a Rapid Time to Market for Solutions

• Salesforce Optimization

• Departmental Budget Management

• Drug Discovery and Basic Research Data Collection & Reporting

• Manufacturing Quality Control

• Data Collection and Reporting for Scouts in the Field

• Clinical Trial Data Analytics

• …

Cambridge Semantics Solutions in Life Sciences

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Thank you.

rob@cambridgesemantics.com