Pulmonary Vascular Research Institute
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Transcript of Pulmonary Vascular Research Institute
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Pulmonary Hypertension In Developing World
An Overview
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Schistosomiasis10-20 M
High altitude5-7 M
Others
HIV
PHT in the Developing
World15-30 MPHT
in the developed world
0.5- 1 M
Pulmonary Hypertension in the world
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Pulmonary Hypertension Associated with:
• Schistosomiasis • HIV • Congenital Heart Disease • Rheumatic valvular diseases • Chagas disease• Endomyocardial Fibrosis• High Altitude• Haemolytic anemia
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Severe PHT due to Schistosomiasis
Courtesy of Dr. Ângela Pontes Bandeira
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High altitude associated pulmonary hypertension
• More than 140 million people worldwide live >2500 m above sea level. – 80 M in Asia,– 35 M Andean mountains
• Genetic predisposition
• Other environmental factors
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HIV associated pulmonary hypertension
• The prevalence is 0.5%• In Africa suggested that the prevalence
may range from 0.6% to 5%, – with higher numbers in the hospitalized as
opposed to ambulant patients
• The incidence however has not been affected by the introduction of the HAART treatment
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Cardiac conditions associated pulmonary hypertension
• Cardiac pathology in the developing world may differ– Congenital heart diseases treated late– Pattern of the pathology may differ– Rheumatic fever and Rh.H.D.– Endomyocardial fibrosis– Chagas diseases
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PVRI in Latin AmericaPVRI in Latin America
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PVRI in China