Pulmonary Histology Vinod Voleti (vbv2101). Zones 1)Conducting -Warm -Filter -Moisten 2) Respiratory...
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Transcript of Pulmonary Histology Vinod Voleti (vbv2101). Zones 1)Conducting -Warm -Filter -Moisten 2) Respiratory...
![Page 1: Pulmonary Histology Vinod Voleti (vbv2101). Zones 1)Conducting -Warm -Filter -Moisten 2) Respiratory - Gas Exchange.](https://reader036.fdocuments.us/reader036/viewer/2022070310/5528bde5497959977d8fd39f/html5/thumbnails/1.jpg)
Pulmonary Histology
Vinod Voleti (vbv2101)
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Zones1) Conducting
- Warm
- Filter
- Moisten
2) Respiratory
- Gas Exchange
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Zones1) Conducting
1) Trachea2) Bronchi3) Bronchioles
1) Large2) Smaller3) Terminal
2) Respiratory1) Respiratory Bronchioles
1) Initial2) Distal
2) Alveolar Ducts3) Alveoli
You should:
** Roughly ID each
** Know Cell Types
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Trachea
C-Shaped Cartilage -maintains patency, especially during forced expiration
-Pseudostratified ciliated columnar epithelium-Goblet cells-Basal cells-Brush cells
Glands:Mucous- mucinSerous- Glycoproteins, polysacharides & bacteriosidic proteins
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Trachea
Basal Bodies: Associated with cilia and highly eosinophilic
Mucous gland vs. serous gland
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Bronchus – Bronchiole Junction
• Bronchus is the last place you’ll see cartilage
• You still have smooth muscle in bronchioles
• Transition from pseudostratified to simple columnar
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Conducting-Respiratory Junction• The Respiratory
segment begins w/ the respiratory bronchioles– Alveoli out-pocketings
– Clara cells begin to predominate
Lab 13 #12
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The Respiratory Segment
• Respiratory Bronchioles – Give off Alveoli– Give off alveolar ducts
• Alveolar ducts– Give off Alveoli only
• Alveolar sacs– Spaces surrounded byclusters of alveoli
Lab 13 #15
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Identify the Segments . .
• Largest = Terminal Bronchiole– Simple epithelium
– No Alveoli (i.e. not respiratory)
• Central clearing = Alveolar ducts– Give off Alveoli only
Lab 13 #17
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The Cells• Type I Pneumocytes
(epithelial cells)• Type II Pneumocytes
(Surfactant Cells)– secrete surfactant
– BIG, at corners of alveoli
– EM: Golgi and rER, laminar bodies of stored surfactant
• Macrophages (Dust)– within the alveolar space
Lab 13 #18
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Elastic Tissue
• Elastin is present throughout the respiratory tract
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The Gas Exchange
• Air Space• Type I pneumocyte• Blood Vessels
– RBC’s
• Macrophages– within the alveolar
space
Lab 13 #13