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Publikationen Infektiologie Freiburg (seit 2002, Stand 06 ...€¦ · Publikationen Infektiologie...
Transcript of Publikationen Infektiologie Freiburg (seit 2002, Stand 06 ...€¦ · Publikationen Infektiologie...
Publikationen Infektiologie Freiburg (seit 2002, Stand 06.04.2017)
Begutachtete Originalarbeiten
2017
Weisser M, Theilacker C, Sutter ST, Babikir R, Bertz H, Götting T, Dettenkofer M, Kern WV, Widmer AF; for the Hospital Infection
Surveillance System for Patients with Haematologic/Oncologic Malignancies Study Group (ONKO-KISS). Secular trends of bloodstream
infections during neutropenia in 15,181 haematopoietic stem cell transplants: 13-year results from a European multicentre surveillance study
(ONKO-KISS). Clin Microbiol Infect 2017 Mar 30. [Epub ahead of print]
Joost I, Kaasch A, Pausch C, Peyerl-Hoffmann G, Schneider C, Voll RE, Seifert H, Kern WV, Rieg S. Staphylococcus aureus bacteremia in
patients with rheumatoid arthritis - data from the prospective INSTINCT cohort. J Infect 2017 Mar 18. [Epub ahead of print]
Kohler V, Probst I, Aufschnaiter A, Büttner S, Schaden L, Rechberger GN, Koraimann G, Grohmann E, Keller W. Conjugative type IV
secretion in Gram-positive pathogens: TraG, a lytic transglycosylase and endopeptidase, interacts with translocation channel protein TraM.
Plasmid 2017; 91:9-18.
Ruffing U, Alabi A, Kazimoto T, Vubil DC, Akulenko R, Abdulla S, Alonso P, Bischoff M, Germann A, Grobusch MP, Helms V, Hoffmann
J, Kern WV, Kremsner PG, Mandomando I, Mellmann A, Peters G, Schaumburg F, Schubert S, Strauß L, Tanner M, Briesen HV, Wende L,
Müller LV, Herrmann M. Community-associated Staphylococcus aureus from Sub-Saharan Africa and Germany: a cross-sectional
geographic correlation study. Sci Rep 2017; 7:154.
Mischnik A, Baumert P, Hamprecht A, Rohde AM, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M,
Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern WV; for the DZIF-ATHOS Study Group. In vitro susceptibility to 19 agents other
than β-lactams among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission. J Antimicrob
Chemother 2017 Jan 19. [Epub ahead of print]
Hos NJ, Jazmati N, Stefanik D, Hellmich M, AlSael H, Kern WV, Rieg S, Wisplinghoff H, Seifert H, Kaasch AJ. Determining vancomycin
Etest MICs in patients with MRSA bloodstream infection does not support switching antimicrobials. J Infect 2017; 74:248-59.
Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M,
Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern WV; for the DZIF-ATHOS Study Group. Susceptibility to cephalosporin
combinations and aztreonam/avibactam among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission.
Int J Antimicrob Agents 2017; 49:239-42.
Mischnik A, Baumert P, Hamprecht A, Rohde A, Peter S, Feihl S, Knobloch J, Gölz H, Kola A, Obermann B, Querbach C, Willmann M,
Gebhardt F, Tacconelli E, Gastmeier P, Seifert H, Kern WV; for the DZIF-ATHOS Study Group. Susceptibility to penicillin derivatives
among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission. Diagn Microbiol Infect Dis 2017;
87:71-3.
Anjum R, Grohmann E, Krakat N. Anaerobic digestion of nitrogen rich poultry manure: Impact of thermophilic biogas process on metal
release and microbial resistances. Chemosphere 2017; 168:1637-47.
2016
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M,
Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss
MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach
A,Henneke P, Triantafyllopoulou A. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-
1280.
Bender JK, Fleige C, Klare I, Fiedler S, Mischnik A, Mutters NT, Dingle KE, Werner G. Detection of a cfr(B) Variant in German
Enterococcus faecium clinical isolates and the impact on linezolid resistance in Enterococcus spp. PLoS One 2016; 11:e0167042.
Joost I, Steinfurt J, Meyer PT, Kern WV, Rieg S. Staphylococcus aureus bacteremia with iliac artery endarteritis in a patient receiving
ustekinumab. BMC Infect Dis 2016; 16:586.
Rieg S, Joost I, Weiß V, Peyerl-Hoffmann G, Schneider C, Hellmich M, Seifert H, Kern WV, Kaasch A. Combination antimicrobial therapy
in patients with Staphylococcus aureus bacteremia - a post hoc analysis in 964 prospectively evaluated patients. Clin Microbiol Infect 2016
S1198-743X(16)30370-6.
Hamprecht A, Rohde AM, Behnke M, Feihl S, Gastmeier P, Gebhardt F, Kern WV, Knobloch JK, Mischnik A, Obermann B, Querbach C,
Peter S, Schneider C, Schröder W, Schwab F, Tacconelli E, Wiese-Posselt M, Wille T, Willmann M, Seifert H, Zweigner J; DZIF-ATHOS
Study Group. Colonization with third-generation cephalosporin-resistant Enterobacteriaceae on hospital admission: prevalence and risk
factors. J Antimicrob Chemother 2016; 71:2957-63.
Pollack LA, Plachouras D, Sinkowitz-Cochran R, Gruhler H, Monnet DL, Weber JT; Transatlantic Taskforce on Antimicrobial Resistance
(TATFAR) Expert Panel on Stewardship Structure and Process Indicators. A concise set of structure and process indicators to assess and
compare antimicrobial stewardship srograms among EU and US hospitals: results from a multinational expert panel. Infect Control Hosp
Epidemiol 2016; 37:1201-11.
Begutachtete Originalarbeiten
Übersichten, Monographien,
Buchbeiträge, Letters/short reports,
Journal supplement-Arbeiten
Goetting T, Klassen S, Jonas D, Benk C, Serr A, Wagner D, Ebner W. Heater-cooler units - contamination of crucial devices in
cardiothoracic surgery! J Hosp Infec 2016; 93:223-8.
Borde JP, Nussbaum S, Hauser S, Hehn P, Hübner J, Sitaru G, Köller S, Schweigert B, deWith K, Kern WV, Kaier K. Implementing an
intensified antibiotic stewardship programme targeting daptomycin use in orthopaedic surgery: a cost-benefit analysis from the hospital
perspective. Infection 2016; 44:301-7.
Albrecht C, Ringshausen F, Ott S, Wagner D, Rademacher J, Schneider M, Welte T, Pletz MW. Should all adult cystic fibrosis patients with
repeated NTM cultures receive treatment? Eur Resp J 2016; 47:1575-7.
Paganelli FL, Huebner J, Singh KV, Zhang X, van Schaik W, Wobser D, Braat JC, Murray BE, Bonten MJ, Willems RJ, Leavis HL.
Genome-wide screening identifies phosphotransferase system permease BepA to be involved in Enterococcus faecium endocarditis and
biofilm formation. J Infect Dis 2016; 214:189-95.
Bätzing-Feigenbaum J, Schulz M, Schulz M, Hering R, Kern WV. Antibiotikaverordnung in der ambulanten Versorgung – eine
bevölkerungsbezogene Untersuchung in Deutschland zum regionalen, altersgruppenbezogenen Verbrauch von Cephalosporinen und
Fluorchinolonen. Dtsch Ärztebl 2016; 113:455-9.
Fätkenheuer G, Jessen H, Stoehr A, Jung N, Jessen AB, Kümmerle T, Berger M, Bogner JR, Spinner CD, Stephan C, Degen O, Vogelmann
R, Spornraft-Ragaller P, Schnaitmann E, Jensen B, Ulmer A, Kittner JM, Härter G, Malfertheiner P, Rockstroh J, Knecht G, Scholten S,
Harrer T, Kern WV, Salzberger B, Schürmann D, Ranneberg B. PEPDar: A randomized prospective noninferiority study of ritonavir-boosted
darunavir for HIV post-exposure prophylaxis. HIV Med 2016; 17:453-9.
Schuster S, Vavra M, Kern WV. Evidence of a substrate discriminating entrance channel in the lower porter domain of the multidrug
resistance efflux pump AcrB. Antimicrob Agents Chemother 2016; 60:4315-23.
Fercher C, Probst I, Kohler V, Goessweiner-Mohr N, Arends K, Grohmann E, Zangger K, Meyer NH, Keller W. VirB8-like protein TraH is
crucial for DNA transfer in Enterococcus faecalis. Sci Rep 2016; 6:24643.
Ringshausen FC, Wagner D, de Roux A, Diel R, Hohmann D, Hickstein L, Welte T, Rademacher J. Prevalence of nontuberculous
mycobacterial pulmonary disease, Germany, 2009–2014. Emerg Infect Dis 2016; 22:1102-5.
Diederich AK, Duda KA, Romero-Saavedra F, Engel R, Holst O, Huebner J. Deletion of fabN in Enterococcus faecalis results in unsaturated
fatty acid auxotrophy and decreased release of inflammatory cytokines. Innate Immun 2016; 22:284-93.
Fiedler S, Bender JK, Klare I, Halbedel S, Grohmann E, Szewzyk U, Werner G. Tigecycline resistance in clinical isolates of Enterococcus
faecium is mediated by an upregulation of plasmid-encoded tetracycline determinants tet(L) and tet(M). J Antimicrob Chemother 2016;
71:871-81.
Teófilo E, Rocha-Pereira N, Kuhlmann B, Antela A, Knechten H, Santos J, Jiménez-Expósito MJ; REMAIN study group. Long-term
efficacy, tolerability, and renal safety of atazanavir/ritonavir-based antiretroviral therapy in a cohort of treatment-naïve patients with HIV-1
infection: the REMAIN study. HIV Clin Trials 2016; 17:17-28.
Nöstlinger C, Platteau T, Bogner J, Buyze J, Dec-Pietrowska J, Dias S, Newbury-Helps J, Kocsis A, Mueller M, Rojas D, Stanekova D, van
Lankveld J, Colebunders R. Computer-assisted intervention for safer sex in HIV-positive men having sex with men: findings of a European
randomized multi-center trial. J Acquir Immune Defic Syndr 2016; 71:e63-72.
Bohnert J, Schuster S, Kern WV, Karcz T, Olejarz A, Kaczor A, Handzlik J, Kieć-Kononowicz K. Novel piperazine arylideneimidazolones
inhibit the AcrAB-TolC pump in Escherichia coli and simultaneously act as fluorescent membrane probes in a combined real-time influx and
efflux assay. Antimicrob Agents Chemother 2016; 60:1974-83.
Strauß L, Ruffing U, Abdulla S, Alabi A, Akulenko R, Garrine M, Germann A, Grobusch MP, Helms V, Herrmann M, Kazimoto T, Kern W,
Mandomando I, Peters G, Schaumburg F, von Müller L, Mellmann A. Detecting Staphylococcus aureus virulence and resistance genes: a
comparison of whole-genome sequencing and DNA microarray technology. J Clin Microbiol 2016; 54:1008-16.
Theilacker C, Ludewig K, Serr A, Schimpf J, Held J, Bögelein M, Bahr V, Rusch S, Pohl A, Kogelmann K, Frieseke S, Bogdanski R,
Brunkhorst FM, Kern WV. Overwhelming post-splenectomy infection: a prospective multicenter cohort study. Clin Infect Dis 2016; 62:871-
8.
Burgey C, Kern WV, Römer W, Rieg S. Differential induction of innate defense antimicrobial peptides in primary nasal epithelial cells upon
stimulation with inflammatory cytokines, Th17 cytokines or bacterial conditioned medium from Staphylococcus aureus isolates. Microb
Pathog 2016; 90:69-77.
Walker M, Mabud TS, Olliaro PL, Coulibaly JT, King CH, Raso G, Scherrer AU, Stothard JR, Sousa-Figueiredo JC, Stete K, Utzinger J,
Basáñez MG. New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to
treatment with praziquantel. Parasit Vectors 2016; 9:41.
Blauenfeldt T, Wagner D, Aabye M, Heyckendorf J, Lange L, Lange C, Ernst M, Ravn P, Duarte R, Morais C, Hoffmann M, Schoch O,
Dominguez J, Latorre I, Ruhwald M. Thermostability of IFN-γ and IP-10 release assays for latent infection with Mycobacterium
tuberculosis: A TBnet study. Tuberculosis (Edinb) 2016; 98:7-12.
2015
Krauth SJ, Greter H, Stete K, Coulibaly JT, Traoré SI, Ngandolo BN, Achi LY, Zinsstag J, N'Goran EK, Utzinger J. All that is blood is not
schistosomiasis: experiences with reagent strip testing for urogenital schistosomiasis with special consideration to very-low prevalence
settings. Parasit Vectors 2015; 8:584.
Guzmán-Prieto AM, Urbanus RT, Zhang X, Bierschenk D, Koekman CA, van Luit-Asbroek M, Ouwerkerk JP, Pape M, Paganelli FL,
Wobser D, Huebner J, Hendrickx AP, Bonten MJ, Willems RJ, van Schaik W. The N-terminal domain of the thermo-regulated surface
protein PrpA of Enterococcus faecium binds to fibrinogen, fibronectin and platelets. Sci Rep 2015; 5:18255.
Christoph A, Ehm C, de With K. [Impact of an ABS training initiative on ABS structural quality of participating hospitals]. Z Evid Fortbild
Qual Gesundhwes 2015; 109:521-7.
Kern WV, Fellhauer M, Hug M, Hoppe-Tichy T, Först G, Steib-Bauert M, de With K. [Recent antibiotic use in German acute care hospitals
- from benchmarking to improved prescribing and quality care]. Dtsch Med Wochenschr 2015; 140:e237-46.
Borde JP, Nussbaum S, Hauser S, Hehn P, Hübner J, Sitaru G, Köller S, Schweigert B, deWith K, Kern WV, Kaier K. Implementing an
intensified antibiotic stewardship programme targeting daptomycin use in orthopaedic surgery: a cost-benefit analysis from the hospital
perspective. Infection 2015 Oct 16 [Epub ahead of print]
Rieg S, Küpper MF, de With K, Serr A, Bohnert JA, Kern WV. Intestinal decolonization of Enterobacteriaceae producing extended-
spectrum β-lactamases (ESBL): a retrospective observational study in patients at risk for infection and a brief review of the literature. BMC
Infect Dis 2015; 15:475.
Ichikawa K, van Ingen J, Koh WJ, Wagner D, Salfinger M, Inagaki T, Uchiya KI, Nakagawa T, Ogawa K, Yamada K, Yagi T. Genetic
diversity of clinical Mycobacterium avium subsp. hominissuis and Mycobacterium intracellulare isolates causing pulmonary diseases
recovered from different geographical regions. Infect Genet Evol 2015; 36:250-255.
Mutters NT, Zimmermann S, Kaase M, Mischnik A. Activity of temocillin, mecillinam, ceftazidime, and ceftazidime/avibactam against
carbapenem-non-susceptible Enterobacteriaceae without carbapenemase production. Eur J Clin Microbiol Infect Dis. 2015 Oct 3. [Epub
ahead of print]
Eichenberger EM, Thaden JT, Sharma-Kuinkel1B, Park1 LP, Rude1TH, Ruffin F, Hos NJ, Seifert H, Rieg S, Kern WV, Lower SK, Fowler
VG, Kaasch AJ. Polymorphisms in fibronectin binding proteins A and B among Staphylococcus aureus bloodstream isolates are not
associated with arthroplasty infection. PLoS One 2015; 53:227-36.
Kodali S, Vinogradov E, Lin F, Khoury N, Hao L, Pavliak V, Jones CH, Laverde D, Huebner J, Jansen KU, Anderson AS, Donald RG. A
vaccine approach for the prevention of infections by multidrug-resistant Enterococcus faecium. J Biol Chem 2015; 290:19512-26.
Romero-Saavedra F, Laverde D, Budin-Verneuil A, Muller C, Bernay B, Benachour A, Hartke A, Huebner J. Characterization of two metal
binding lipoproteins as vaccine candidates for enterococcal infections. PLoS One 2015; 10:e0136625.
Kaasch AJ, Fätkenheuer G, Prinz-Langenohl R, Paulus U, Hellmich M, Weiß V, Jung N, Rieg S, Kern WV, Seifert H; SABATO Trial
Group. Early oral switch therapy in low-risk Staphylococcus aureus bloodstream infection (SABATO): study protocol for a randomized
controlled trial. Trials 2015;16:450.
Kohler P, Kuster SP, Bloemberg G, Schulthess B, Frank M, Tanner FC, Rössle M, Böni C, Falk V, Wilhelm MJ, Sommerstein R,
Achermann Y, Ten Oever J, Debast SB, Wolfhagen MJ, Brandon Bravo Bruinsma GJ, Vos MC, Bogers A, Serr A, Beyersdorf F, Sax H,
Böttger EC, Weber R, van Ingen J, Wagner D, Hasse B. Healthcare-associated prosthetic heart valve, aortic vascular graft, and disseminated
Mycobacterium chimaera infections subsequent to open heart surgery. Eur Heart J; 36:2745-53.
Olliaro PL, Vaillant M, Diawara A, Coulibaly JT, Garba A, Keiser J, King CH, Knopp S, Landouré A, N'Goran EK, Raso G, Scherrer AU,
Sousa-Figueiredo JC, Stete K, Zhou XN, Utzinger J. Toward Measuring Schistosoma Response to Praziquantel Treatment with Appropriate
Descriptors of Egg Excretion. PLoS Negl Trop Dis 2015; 9:e0003821.
Becker SL, Piraisoody N, Kramme S, Marti H, Silué KD, Panning M, Nickel B, Kern WV, Herrmann M, Hatz CF, N'Goran EK, Utzinger J,
von Müller L. Real-time PCR for detection of Strongyloides stercoralis in human stool samples from Côte d'Ivoire: Diagnostic accuracy,
inter-laboratory comparison and patterns of hookworm co-infection. Acta Trop 2015; 150:210-7.
Zischka M, Künne CT, Blom J, Wobser D, Sakιnç T, Schmidt-Hohagen K, Dabrowski PW, Nitsche A, Hübner J, Hain T, Chakraborty T,
Linke B, Goesmann A, Voget S, Daniel R, Schomburg D, Hauck R, Hafez HM, Tielen P, Jahn D, Solheim M, Sadowy E, Larsen J, Jensen
LB, Ruiz-Garbajosa P, Quiñones Pérez D, Mikalsen T, Bender J, Steglich M, Nübel U, Witte W, Werner G. Comprehensive molecular,
genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40. BMC Genomics 2015; 16:175.
Ocvirk S, Sava IG, Lengfelder I, Lagkouvardos I, Steck N, Roh JH, Tchaptchet S, Bao Y, Hansen JJ, Huebner J, Carroll IM, Murray BE,
Sartor RB, Haller D. Surface-associated lipoproteins link Enterococcus faecalis virulence to colitogenic activity in IL-10-deficient mice
independent of their expression levels. PLoS Pathog 2015; 11:e1004911.
Letang E, Müller MC, Ntamatungiro AJ, Kimera N, Faini D, Furrer H, Battegay M, Tanner M, Hatz C, Boulware DR, Glass TR.
Cryptococcal antigenemia in immunocompromised human immunodeficiency virus patients in rural Tanzania: a preventable cause of early
mortality. Open Forum Infect Dis 2015; 2:ofv046.
Cardot-Martin E, Casalegno JS, Badiou C, Dauwalder O, Keller D, Prévost G, Rieg S, Kern WV, Cuerq C, Etienne J, Vandenesch F, Lina G,
Dumitrescu O. α-Defensins partially protect human neutrophils against Panton-Valentine leukocidin produced by Staphylococcus aureus.
Lett Appl Microbiol 2015; 61:158-64.
Stete K, Kern WV, Rieg S, Serr A, Maurer C, Tintelnot K, Wagner D. Importierte Histoplasmose. Dtsch Med Wochenschr 2015; 140: 913-6.
Theilacker C, Diederich AK, Otto A, Sava IG, Wobser D, Bao Y, Hese K, Broszat M, Henneke P, Becher D, Huebner J. Enterococcus
faecalis glycolipids modulate lipoprotein-content of the bacterial cell membrane and host immune response. PLoS One 2015; 10:e0132949.
Borde JP, Häcker GA, Guschl S, Serr A, Danner T, Hübner J, Burrack-Lange S, Lüdke G, Helwig P, Hauschild O, Kern WV. Diagnosis of
prosthetic joint infections using UMD-Universal Kit and the automated multiplex-PCR Unyvero i60 ITI® cartridge system: a pilot study.
Infection 2015; 43:551-60.
Scholman T, Straub M, Sotgiu G, Elsäßer J, Leyking S, Singh M, Sester U, Wagner D, Sester M. Superior sensitivity of ex vivo IFN-Ɣ
release assays as compared to skin-testing in immunocompromised patients. Am J Transplant 2015; 15: 2616-2624.
Pulcini C, Wencker F, Frimodt-Møller N, Kern WV, Nathwani D, Rodríguez-Baño J, Simonsen GS, Vlahović-Palčevski V, Gyssens IC;
ESGAP Curriculum Working Group. European survey on principles of prudent antibiotic prescribing teaching in undergraduate students.
Clin Microbiol Infect 2015; 21:354-61.
Rossmann FS, Laverde D, Kropec A, Romero-Saavedra F, Meyer-Buehn M, Huebner J. Isolation of highly active monoclonal antibodies
against multiresistant gram-positive bacteria. PLoS One 2015; 10:e0118405.
Jechalke S, Broszat M, Lang F, Siebe C, Smalla K, Grohmann E. Effects of 100 years wastewater irrigation on resistance genes, class 1
integrons and IncP-1 plasmids in Mexican soil. Front Microbiol 2015; 6:163.
Rossmann FS, Racek T, Wobser D, Puchalka J, Rabener EM, Reiger M, Hendrickx AP, Diederich AK, Jung K, Klein C, Huebner J. Phage-
mediated dispersal of biofilm and distribution of bacterial virulence genes is induced by quorum sensing. PLoS Pathog 2015; 11:e100465.
Guridi A, Diederich AK, Aguila-Arcos S, Garcia-Moreno M, Blasi R, Broszat M, Schmieder W, Clauss-Lendzian E, Sakinc-Gueler T,
Andrade R, Alkorta I, Meyer C, Landau U, Grohmann E. New antimicrobial contact catalyst killing antibiotic resistant clinical and
waterborne pathogens. Mater Sci Eng C Mater Biol Appl 2015; 50:1-11.
Augustin J, Mangiapane S, Kern WV. A regional analysis of outpatient antibiotic prescribing in Germany in 2010. Eur J Public Health 2015;
25:397-9.
Gross BN, Steib-Bauert M, Kern WV, Knoth H, Borde JP, Krebs S, Hug MJ, Rothe U, Maier L, de With K. Hospital use of systemic
antifungal drugs: a multi-center surveillance update from Germany. Infection 2015; 43:423-9 .
Burgey C, Kern WV, Römer W, Sakinc T, Rieg S. The innate defense antimicrobial peptides hBD3 and RNase7 are induced in human
umbilical vein endothelial cells by classical inflammatory cytokines but not Th17 cytokines. Microbes Infect 2015; 17:353-9.
Borde JP, Litterst S, Ruhnke M, Feik R, Hübner J, deWith K, Kaier K, Kern WV. Implementing an intensified antibiotic stewardship
programme targeting cephalosporin and fluoroquinolone use in a 200-bed community hospital in Germany. Infection 2015; 43:45-50.
Rossmann FS, Kropec A, Laverde D, Saaverda FR, Wobser D, Huebner J. In vitro and in vivo activity of hyperimmune globulin preparations
against multiresistant nosocomial pathogens. Infection 2015; 43:169-75.
Borde JP, Kern WV, Hug M, Steib-Bauert M, de With KD, Busch HJ, Kaier K. Implementation of an intensified antibiotic stewardship
programme targeting third-generation cephalosporin and fluoroquinolone use in an emergency medicine department. Emerg Med J 2015;
32:509-15.
Hos NJ, Rieg S, Kern WV, Jonas D, Fowler VG Jr, Higgins PG, Seifert H, Kaasch AJ. Amino acid alterations in fibronectin binding protein
A (FnBPA) and bacterial genotype are associated with cardiac device related infection in Staphylococcus aureus bacteraemia. J Infect 2015;
70:153-9.
2014
Schuster S, Kohler S, Buck A, Dambacher C, König A, Bohnert JA, Kern WV. Random mutagenesis of the multidrug transporter AcrB from
Escherichia coli for identification of putative target residues of efflux pump inhibitors. Antimicrob Agents Chemother 58 (2014) 6870-8.
Yamaguchi N, Roberts M, Castro S, Oubre C, Makimura K, Leys N, Grohmann E, Sugita T, Ichijo T, Nasu M. Microbial monitoring of
crewed habitats in space-current status and future perspectives. Microbes Environ 29 (2014) 250-60.
Clotet B, Feinberg J, van Lunzen J, Khuong-Josses MA, Antinori A, Dumitru I, Pokrovskiy V, Fehr J, Ortiz R, Saag M, Harris J, Brennan C,
Fujiwara T, Min S; ING114915 Study Team. Once-daily dolutegravir versus darunavir plus ritonavir in antiretroviral-naive adults with HIV-
1 infection (FLAMINGO): 48 week results from the randomised open-label phase 3b study. Lancet 383 (2014) 2222-31.
Earnshaw S, Mancarella G, Mendez A, Todorova B, Magiorakos AP, Possenti E, Stryk M, Gilbro S, Goossens H, Albiger B, Monnet DL;
European Antibiotic Awareness Day Technical Advisory Committee; European Antibiotic Awareness Day Collaborative Group. European
Antibiotic Awareness Day: a five-year perspective of Europe-wide actions to promote prudent use of antibiotics. Euro Surveill 19 (2014)
20928.
Nurjadi D, Olalekan AO, Layer F, Shittu AO, Alabi A, Ghebremedhin B, Schaumburg F, Hofmann-Eifler J, Van Genderen PJ, Caumes E,
Fleck R, Mockenhaupt FP, Herrmann M, Kern WV, Abdulla S, Grobusch MP, Kremsner PG, Wolz C, Zanger P. Emergence of trimethoprim
resistance gene dfrG in Staphylococcus aureus causing human infection and colonization in sub-Saharan Africa and its import to Europe. J
Antimicrob Chemother 69 (2014) 2361-8.
Breuninger M, van Ginneken B, Philipsen RH, Mhimbira F, Hella JJ, Lwilla F, van den Hombergh J, Ross A, Jugheli L, Wagner D, Reither
K. Diagnostic accuracy of computer-aided detection of pulmonary tuberculosis in chest radiographs: a validation study from sub-Saharan
Africa. PLoS One. 2014 Sep 5;9(9):e106381.
Hufnagel M, Sixel K, Hammer F, Kropec A, Sava IG, Theilacker C, Berner R, Huebner J. Detection of opsonic antibodies against
Enterococcus faecalis cell wall carbohydrates in immune globulin preparations. Infection 42 (2014) 749-55.
Broszat M, Nacke H, Blasi R, Siebe C, Huebner J, Daniel R, Grohmann E. Wastewater irrigation increases abundance of potentially harmful
Gammaproteobacteria in soils from Mezquital Valley, Mexico. Appl Environ Microbiol 80 (2014) 5282-91.
Helwig P, Morlock J, Oberst M, Hauschild O, Hübner J, Borde J, Südkamp NP, Konstantinidis L. Periprosthetic joint infection – effect on
quality of life. Int Orthop 38 (2014) 1077-81.
Borde JP, Batin N, Rieg S, Feik R, Reimling C, Kern WV, de With K, Hübner J, Ruhnke M, Kaier K. Adherence to an antibiotic stewardship
bundle targeting Staphylococcus aureus blood stream infections at a 200-bed community hospital. Infection 42 (2014) 713-9.
Borde JP, Kaier K, Steib-Bauert M, Vach W, Geibel-Zehender A, Busch H, Bertz H, Hug M, de With K, Kern WV. Feasibility and impact of
an intensified antibiotic stewardship programme targeting cephalosporin and fluoroquinolone use in a tertiary care university medical center.
BMC Infect Dis 14 (2014) 201.
Diederich AK, Wobser D, Spiess M, Sava IG, Huebner J, Sakιnç T. Role of glycolipids in the pathogenesis of Enterococcus faecalis urinary
tract infection. PLoS One 9 (2014) e96295.
Goessweiner-Mohr N, Eder M, Hofer G, Fercher C, Arends K, Birner-Gruenberger R, Grohmann E, Keller W. Structure of the double-
stranded DNA-binding type IV secretion protein TraN from Enterococcus. Acta Crystallogr D Biol Crystallogr 70 (2014) 2376-89
Goessweiner-Mohr N, Fercher C, Arends K, Birner-Gruenberger R, Laverde-Gomez D, Huebner J, Grohmann E, Keller W. The type IV
secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold. Acta Crystallogr D Biol Crystallogr 70
(2014) 1124-35.
Sester M, van Leth F, Bruchfeld J, Bumbacea D, Cirillo DM, Dilektasli AG, Domínguez J, Duarte R, Ernst M, Eyuboglu FO, Gerogianni I,
Girardi E, Goletti D, Janssens JP, Julander I, Lange B, Latorre I, Losi M, Markova R, Matteelli A, Milburn H, Ravn P, Scholman T, Soccal
PM, Straub M, Wagner D, Wolf T, Yalcin A, Lange C; TBNET. Risk assessment of zuberculosis in immunocompromised patients. A
TBNET study. Am J Respir Crit Care Med 190 (2014) 1168-76.
Haller C, Berthold M, Wobser D, Kropec A, Lauriola M, Schlensak C, Huebner J. Cell-wall glycolipid mutations and their effects on
virulence of E. faecalis in a rat model of infective endocarditis. PLoS One 9 (2014) e91863.
Kaasch AJ, Barlow G, Edgeworth JD, Fowler VG Jr, Hellmich M, Hopkins S, Kern WV, Llewelyn M, Rieg S, Rodriguez-Baño J,
Scarborough M, Seifert H, Soriano A, Tilley R, Tőrők ME, Weiß V, Wilson WR, Thwaites GE, on behalf of ISAC, UKCIRG, SABG, and
INSTINCT. Staphylococcus aureus bloodstream infection: a pooled analysis of five prospective, observational studies. J Infect 68 (2014)
242-51.
Thern J, de With K, Strauss R, Steib-Bauert M, Weber N, Kern WV. Selection of hospital antimicrobial prescribing quality indicators: a
consensus among German antibiotic stewardship (ABS) networkers. Infection 42 (2014) 351-62.
Kaasch AJ, Rieg S, Hellmich M, Kern WV, Seifert H. Differential time to positivity is not predictive for central line-related Staphylococcus
aureus bloodstream infection in routine clinical care. J Infect. 68 (2014) 58-61.
Romero-Saavedra F, Laverde D, Wobser D, Michaux C, Budin-Verneuil A, Bernay B, Benachour A, Hartke A, Huebner J. Identification of
peptidoglycan-associated proteins as vaccine candidates for enterococcal infections. PLoS One 9 (2014) e111880.
Laverde D, Wobser D, Romero-Saavedra F, Hogendorf W, van der Marel G, Berthold M, Kropec A, Codee J, Huebner J. Synthetic Teichoic
Acid Conjugate Vaccine against Nosocomial Gram-Positive Bacteria. PLoS One 9 (2014) e110953.
Wobser D, Ali L, Grohmann E, Huebner J, Sakinc T. A novel role for D-alanylation of lipoteichoic acid of Enterococcus faecalis in urinary
tract infection. PLoS ONE 9 (2014) e107827.
Diederich A-K, Wobser D, Spiess M, Sava IG, Huebner J, Sakιnç T. 2014. Role of glycolipids in the pathogenesis of Enterococcus faecalis
urinary tract infection. PLoS ONE 9 (2014) e96295.
Rieg S, Saborowski V, Kern WV, Jonas D, Bruckner-Tuderman L, Hofmann SC. Expression of the sweat-derived innate defense
antimicrobial peptide dermcidin is not impaired in Staphylococcus aureus colonisation and recurrent skin infections. Clin Exp Dermatol 39
(2014) 209-12.
Lübbert C, Schumacher U, Stareprawo S, Claus J, Heeß-Erler G, Fiebig C, de With K, Wilhelms D, Kekulé AS, Klöss T, Moritz S. Lässt
sich die Antibiotikaverordnungspraxis im Krankenhaus durch hausinterne Richtlinien beeinflussen? Dtsch Med Wochenschr 139 (2014)
2578-84.
2013
Castillo-Rojas G, Mazari-Hiríart M, Ponce de León S, Amieva-Fernández RI, Agis-Juárez RA, Huebner J, López-Vidal Y. Comparison of
Enterococcus faecium and Enterococcus faecalis strains isolated from water and clinical samples: antimicrobial susceptibility and genetic
relationships. PLoS One 8 (2013) e59491.
Shokoohizadeh L, Mobarez AM, Zali MR, Ranjbar R, Alebouyeh M, Sakinc T, Ali L. High frequency distribution of heterogeneous
vancomycin-resistant Enterococcous faecium (VREfm) in Iranian hospitals. Diagn Pathol 8 (2013) 163.
Borde JP, Offensperger WB, Kern WV, Wagner D. Mycobacterium genavense specific mesenteritic syndrome in HIV-infected patients: a
new entity of retractile mesenteritis? AIDS 27 (2013) 2819-22.
Timmer A, Günther J, Motschall E, Rücker G, Antes G, Kern WV. Pelargonium sidoides extract for treating acute respiratory tract
infections. Cochrane Database Syst Rev 2013; 10:CD006323
Buyle FM, Metz-Gercek S, Mechtler R, Kern WV, Robays H, Vogelaers D, Struelens MJ; members of the Antibiotic Strategy International
(ABS) Quality Indicators Team. Development and validation of potential structure indicators for evaluating antimicrobial stewardship
programmes in European hospitals. Eur J Clin Microbiol Infect Dis 32 (2013) 1161-70.
Arends K, Celik EK, Probst I, Goessweiner-Mohr N, Fercher C, Grumet L, Soellue C, Abajy MY, Sakin T, Broszat M, Schiwon K,
Koraimann G, Keller W, Grohmann E. TraG encoded by the pIP501 type IV secretion system is a two domain peptidoglycan degrading
enzyme essential for conjugative transfer. J Bacteriol 195 (2013) 4436-44.
Rieg S, Jonas D, Kaasch AJ, Porzelius C, Peyerl-Hoffmann G, Theilacker C, Küpper MF, Schneider C, Seifert H, Kern WV. Microarray-
based genotyping and clinical outcomes of Staphylococcus aureus bloodstream infection: an exploratory study. PLoS One 8 (2013) e71259.
Huebner J, Rack-Hoch AL, Pecar A, Schmid I, Klein C, Borde JP. [Pilot project of a pediatric antibiotic stewardship initiative at the Hauner
Children's Hospital.] Klin Pädiatr 2013 Jul 12. [Epub ahead of print]
Theilacker C, Held J, Allering L, Emmerich P, Schmidt-Chanasit J, Kern WV, Panning M. Prolonged polyarthralgia in a German traveller
with Mayaro virus infection without inflammatory correlates. BMC Infect Dis 13 (2013) 369.
Schiwon K, Arends K, Rogowski KM, Fürch S, Prescha K, Sakinc T, Van Houdt R, Werner G, Grohmann E. Comparison of antibiotic
resistance, biofilm formation and conjugative transfer of Staphylococcus and Enterococcus isolates from international space station and
antarctic research station Concordia. Microb Ecol 65 (2013) 638-51.
Kaasch AJ, Rieg S, Kuetscher J, Brodt HR, Widmann T, Herrmann M, Meyer C, Welte T, Kern P, Haars U, Reuter S, Hübner I, Strauss R,
Sinha B, Brunkhorst FM, Hellmich M, Fätkenheuer G, Kern WV, Seifert H. Delay in the administration of appropriate antimicrobial therapy
in Staphylococcus aureus bloodstream infection: a prospective multicenter hospital-based cohort study. Infection 41 (2013) 979-85.
Falcone V, Bierbaum S, Bertz H, Kern WV, Kontny U, Huzly D, Panning M. Pandemic influenza virus A/H1N1 (2009) hemagglutinin
polymorphism and associated disease in southern Germany during the 2010/11 influenza season. Arch Virol 158 (2013) 1297-303.
Bohnert J, Schuster S, Kern WV. Pimozide inhibits the AcrAB-TolC efflux pump in Escherichia coli.Open Microbiol J 7 (2013) 83-6.
Ringshausen FC, Apel RM, Bange FC, de Roux A, Pletz MW, Rademacher J, Suhling H, Wagner D, Welte T. Burden and trends of
hospitalisations associated with pulmonary non-tuberculous mycobacterial infections in Germany, 2005-2011. BMC Infect Dis 13 (2013)
231.
Hoefsloot W, van Ingen J, Andrejak C, Ängeby K, Bauriaud R, Bemer P, Beylis N, Boeree MJ, Cacho J, Chihota V, Chimara E, Churchyard
G, Cias R, Dasa R, Daley CL, Dekhuijzen PNR, Domingo D, Drobniewski F, Esteban J, Fauville-Dufaux M, Folkvardsen DB, Gibbons N,
Gómez-Mampaso E, Gonzalez R, Hoffmann H, Hsueh PR, Indra A, Jagielski T, Jamieson F, Jankovic M, Jong E, Keane J, Koh WJ, Lange
B, Leao S, Macedo R, Mannsåker T, Marras TK, Maugein J, Milburn HJ, Mlinkó T, Morcillo N, Morimoto K, Papaventsis D, Palenque E,
Paez-Peña M, Piersimoni C, Polanová M, Rastogi N, Richter E, Ruiz-Serrano MJ, Silva A, da Silva MP, Simsek H, van Soolingen D, Szabó
N, Thomson R, Tórtola Fernandez MT, Tortoli E, Totten SE, Tyrrell G, Vasankari T, Villar M, Walkiewicz R, Winthrop K, Wagner D, for
NTM-NET 2012. The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: A NTM-NET collaborative
study. Eur Resp J 42 (2013) 1604-13.
Kern WV, Marchetti O, Drgona L, Akan H, Aoun M, Akova M, de Bock R, Paesmans M, Viscoli C, Calandra T, and the EORTC-IDG Trial
XV Investigators. Oral antibiotics for fever in low-risk neutropenic cancer patients: a double-blind, randomized, multicenter trial comparing
single daily moxifloxacin with twice daily ciprofloxacin plus amoxicillin/clavulanic acid combination therapy (European Organization for
Research and Treatment of Cancer protocol 46001, Infectious Diseases Group trial XV). J Clin Oncol 31 (2013) 1149-56.
van der Linden M, Reinert RR, Kern WV, Imöhl M. Epidemiology of serotype 19A isolates from invasive pneumococcal disease in German
children. BMC Infect Dis 13 (2013) 70.
Goessweiner-Mohr N, Grumet L, Pavkov-Keller T, Birner-Gruenberger R, Grohmann E, Keller W. Crystallization and preliminary structure
determination of the transfer protein TraM from the Gram-positive conjugative plasmid pIP501. Acta Crystallogr Sect F Struct Biol Cryst
Commun 69 (2013) 178-83
Goessweiner-Mohr N, Grumet L, Arends K, Pavkov-Keller T, Gruber CC, Gruber K, Birner-Gruenberger R, Kropec-Huebner A, Huebner J,
Grohmann E, Keller W. The 2.5 A structure of the Enterococcus conjugation protein TraM resembles VirB8 type IV secretion proteins. J
Biol Chem 288 (2013) 2018-28.
2012
Stete K, Krauth SJ, Coulibaly JT, Knopp S, Hattendorf J, Müller I, Lohourignon LK, Kern WV, N'goran EK, Utzinger J. Dynamics of
Schistosoma haematobium egg output and associated infection parameters following treatment with praziquantel in school-aged children.
Parasit Vectors 5 (2012) 298.
Sakinc T, Baars B, Wüppenhorst N, Kist M, Huebner J, Opferkuch W. Influence of a 23S ribosomal RNA mutation in Helicobacter pylori
strains on the in vitro synergistic effect of clarithromycin and amoxicillin. BMC Res Notes 5 (2012) 603.
Borde JP, Meier S, Fingerle V, Klier C, Huebner J, Kern WV. CXCL13 may improve diagnosis in early neuroborreliosis with atypical
laboratory findings. BMC Infect Dis 12 (2012) 344.
Goessweiner-Mohr N, Fercher C, Abajy MY, Grohmann E, Keller W. Crystallization and first data collection of the putative transfer protein
TraN from the Gram-positive conjugative plasmid pIP501. Acta Crystallogr Sect F Struct Biol Cryst Commun 68 (2012) 1402-5.
King NP, Sakinç T, Ben Zakour NL, Totsika M, Heras B, Simerska P, Shepherd M, Gatermann SG, Beatson SA, Schembri MA.
Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance. BMC Microbiol 12
(2012) 8.
Zarb P, Amadeo B, Muller A, Drapier N, Vankerckhoven V, Davey P, Goossens H; ESAC-3 Hospital Care Subproject Group. Antimicrobial
prescribing in hospitalized adults stratified by age: data from the ESAC point-prevalence surveys. Drugs Aging 29 (2012) 53-62.
Dalkmann P, Broszat M, Siebe C, Willaschek E, Sakinc T, Huebner J, Amelung W, Grohmann E, Siemens J. Accumulation of
pharmaceuticals, enterococcus, and resistance genes in soils irrigated with wastewater for zero to 100 years in central Mexico. PLoS One 7
(2012) e45397.
Geiss-Liebisch S, Rooijakkers SH, Beczala A, Sanchez-Carballo P, Kruszynska K, Repp C, Sakinc T, Vinogradov E, Holst O, Huebner J,
Theilacker C. Secondary cell wall polymers of Enterococcus faecalis are critical for resistance to complement activation via mannose-
binding lectin. J Biol Chem 287 (2012) 37769-77.
Bouchaud O, Mühlberger N, Parola P, Calleri G, Matteelli A, Peyerl-Hoffmann G, Méchaï F, Gautret P, Clerinx J, Kremsner PG, Jelinek T,
Kaiser A, Beltrame A, Schmid ML, Kern P, Probst M, Bartoloni A, Weinke T, Grobusch MP. Therapy of uncomplicated falciparum malaria
in Europe: MALTHER - a prospective observational multicentre study. Malar J 11 (2012) 212.
Skurnik D, Kropec A, Roux D, Theilacker C, Huebner J, Pier GB. Natural antibodies in normal human sera inhibit Staphylococcus aureus
capsular polysaccharide vaccine efficacy. Clin Infect Dis 55 (2012)1188-97.
Anjum R, Grohmann E, Malik A. Exogenous isolation of conjugative plasmids from pesticide contaminated soil. World J Microbiol
Biotechnol 28 (2012) 567-74.
Bao Y, Sakinc T, Laverde D, Wobser D, Benachour A, Theilacker C, Hartke A, Huebner J. Role of mprF1 and mprF2 in the pathogenicity of
Enterococcus faecalis. PLoS One 7 (2012) e38458.
Buyle F, Metz-Gercek S, Mechtler R, Kern WV, Robays H, Vogelaers D, Struelens M. Prospective multicentre feasibility study of a quality
of care indicator for intravenous to oral switch therapy with highly bioavailable antibiotics. J Antimicrob Chemother 67(8):2043-6.
Hogendorf WF, Kropec A, Filippov DV, Overkleeft HS, Huebner J, van der Marel GA, Codée JD. Light fluorous synthesis of glucosylated
glycerol teichoic acids. Carbohydr Res 356 (2012) 142-51 .
Theilacker C, Holst O, Lindner B, Huebner J, Kaczyński Z. The structure of the wall teichoic acid isolated from Enterococcus faecalis strain
12030. Carbohydr Res 354 (2012) 106-9.
Lange B, Vavra M, Kern WV, Wagner D. Development of tuberculosis in immunocompromised patients with a positive tuberculosis-specific
IGRA. Int J Tuberc Lung Dis 16 (2012) 492-5.
Eicher T, Cha HJ, Seeger MA, Brandstätter L, El-Delik J, Bohnert JA, Kern WV, Verrey F, Grütter MG, Diederichs K, Pos KM. Transport
of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. PNAS 109
(2012) 5687-92.
Arends K, Schiwon K, Sakinc T, Hübner J, Grohmann E. Green fluorescent protein-labeled monitoring tool to quantify conjugative plasmid
transfer between Gram-positive and Gram-negative bacteria. Appl Environ Microbiol 78 (2012) 895-9.
Theilacker C, Kropec A, Hammer F, Sava I, Wobser D, Sakinc T, Codée JDC, Hogendorf WFJ, van der Marel GA Huebner J. Protection
against Staphylococcus aureus by antibody to the polyglycerolphosphate backbone of heterologous lipoteichoic acid. J Infect Dis 205 (2012)
1076-85.
Thoden J, Rieg SR, Venhoff N, Wennekes V, Schmitt-Graeff A, Wagner D, Kern WV. Fatal hemophagocytic syndrome in a patient with a
previously well-controlled asymptomatic HIV infection after EBV reactivation. J Infect 64 (2012) 110-2.
Hofmann SC, Saborowski V, Lange S, Kern WV, Bruckner-Tuderman L, Rieg SR. Expression of innate defence antimicrobial peptides in
hidradenitis suppurativa. J Am Acad Dermatol 66 (2012) 966-74.
2011
Rigottier-Gois L, Alberti A, Houel A, Taly JF, Palcy P, Manson J, Pinto D, Matos RC, Carrilero L, Montero N, Tariq M, Karsens H, Repp C,
Kropec A, Budin-Verneuil A, Benachour A, Sauvageot N, Bizzini A, Gilmore MS, Bessières P, Kok J, Huebner J, Lopes F, Gonzalez-Zorn
B, Hartke A, Serror P. Large-scale screening of a targeted Enterococcus faecalis mutant library identifies envelope fitness factors. PLoS One
6 (2011) e29023.
Bychowska A, Theilacker C, Czerwicka M, Marszewska K, Huebner J, Holst O, Stepnowski P, Kaczyński Z. Chemical structure of wall
teichoic acid isolated from Enterococcus faecium strain U0317. Carbohydr Res 346 (2011): 2816-9.
Balabanova Y, Gilsdorf A, Buda S, Burger R, Eckmanns T, Gärtner B, Groß U, Haas W, Hamouda O, Hübner J, Jänisch T, Kist M, Kramer
MH, Ledig T, Mielke M, Pulz M, Stark K, Suttorp N, Ulbrich U, Wichmann O, Krause G. Communicable diseases prioritized for
surveillance and epidemiological research: results of a standardized prioritization procedure in Germany, 2011. PLoS One 6 (2011) e25691.
Kropec A, Sava IG, Vonend C, Sakinc T, Grohmann E, Huebner J. Identification of SagA as a novel vaccine target for the prevention of
Enterococcus faecium infections. Microbiology 157 (2011) 3429-34.
Hogendorf WF, Meeuwenoord N, Overkleeft HS, Filippov DV, Laverde D, Kropec A, Huebner J, Van der Marel GA, Codée JD. Automated
solid phase synthesis of teichoic acids. Chem Commun (Camb) 47 (2011) 8961-3.
Laverde Gomez JA, Hendrickx AP, Willems RJ, Top J, Sava I, Huebner J, Witte W, Werner G. Intra- and interspecies genomic transfer of
the Enterococcus faecalis pathogenicity island. PLoS One 6 (2011) e16720.
Becker SL, Sieto B, Silué KD, Adjossan L, Koné S, Hatz C, Kern WV, N’Goran EK, Utzinger J. Diagnosis, clinical features, and self-
reported morbidity of Strongyloides stercoralis and hookworm infection in a co-endemic setting. PLoS Negl Dis 5 (2011) e1292.
Anjum R, Grohmann E, Malik A. Molecular characterization of conjugative plasmids in pesticide tolerant and multi-resistant bacterial
isolates from contaminated alluvial soil. Chemosphere 84 (2011) 175-81.
Steffens B, Kümmerle T, Koch S, Birtel A, Schwarze-Zander C, Emmelkamp J, Kern WV, Hertenstein C, Wyen C, Lehmann C, Cornely
OA, Rockstroh J, Fätkenheuer G. Acceptance and tolerability of an adjuvanted nH1N1 vaccine in HIV-infected patients in the Cologne-Bonn
cohort. Eur J Med Res 16 (2011) 289-94.
Bohnert J, Szymaniak-Vits M, Schuster S, Kern WV. Efflux inhibition by selective serotonin reuptake inhibitors in Escherichia coli. J
Antimicrob Chemother 66 (2011) 2057-60.
Geyer M, Wilpert J, Wiech T, Theilacker C, Stubanus M, Kramer-Zucker A, Fischer KG, Drognitz O, Frydrychowicz A, Kern W, Walz G,
Pisarski P. Rapidly progressive hepatic alveolar echinococcosis in an ABO-incompatible renal transplant recipient. Transpl Infect Dis 13
(2011) 278-84.
Held J, Wagner D. β-D-Glucan kinetics for the assessment of treatment response in P. jirovecii pneumonia. Clin Microbiol Infec 17 (2011)
1118-22.
Rieg S, Schmoldt S, Theilacker C, de With K, Wolfel S, Kern WV, Dobler G. Tick-borne lymphadenopathy (TIBOLA) acquired in
Southwestern Germany. BMC Infectious Diseases 11(2011) 167.
Bohnert J, Szymaniak-Vits M, Schuster S, Kern WV. Determination of real-time efflux phenotypes in Escherichia coli AcrB binding pocket
phenylalanine mutants using a 1,2´-dinaphthylamine efflux assay. PLoS One 6 (2011) e21196.
Brandstätter L, Sokolova L, Eicher T, Seeger MA, Briand C, Cha HJ, Cernescu M, Bohnert J, Kern WV, Brutschy B, Pos KM. Analysis of
AcrB and AcrB/DARPin ligand complexes by LILBID MS. Biochim Biophys Acta 1808 (2011) 2189-96.
Kaasch AJ, Fowler VGJr, Rieg S, Peyerl-Hoffmann G, Birkholz H, Hellmich M, Kern WV, Seifert H. Use of a simple criteria set for guiding
echocardiography in nosocomial Staphylococcus aureus bacteremia. Clin Infect Dis 53 (2011) 1-9.
Becker SL, Lohourignon LK, Speich B, Rinaldi L, Knopp S, N’Goran EK, Cringoli G, Utzinger J. Comparison of the FLOTAC-400 dual
technique and the formalin-ether concentration technique for the diagnosis of human intestinal protozoa infection. J Clin Microbiol 49 (2011)
2183-90.
Rieg SR, Kaasch AJ, Wehrle J, Hofmann SC, Szymaniak-Vits M, Saborowski V, Jonas D, Kalbacher H, Seifert H, Kern WV. Susceptibility
of clinical Staphylococcus aureus isolates to innate defense antimicrobial peptides. Microbes Infect 13 (2011) 761-5.
Ness T, Kern WV, Frank U, Reinhard T. Postoperative nosocomial endophthalmitis: is perioperative antibiotic prophylaxis advisable? A
single centre's experience. J Hosp Infect 78 (2011) 138-42.
Theilacker C, Sava I, Sanchez-Carballo P, Bao Y, Kropec A, Grohmann E, Holst O, Huebner J. Deletion of the glycosyltransferase bgsB of
Enterococcus faecalis leads to a complete loss of glycolipids from the cell membrane and to impaired biofilm formation. BMC Microbiol
11(2011) 67.
Theilacker C, Kaczyński Z, Kropec A, Sava I, Ye L, Bychowska A, Holst O, Huebner J. Serodiversity of opsonic antibodies against
Enterococcus faecalis -glycans of the cell wall revisited. PLoS One 6 (2011) e17839.
Zarb P, Amadeo B, Muller A, Drapier N, Vankerckhoven V, Davey P, Goossens H, on behalf of the ESAC-3 hospital care subproject group.
Identification of targets for quality improvement in antimicrobial prescribing: the web-based ESAC Point Prevalence Survey 2009. J
Antimicrob Chemother 66 (2011) 443-9.
2010
Al-Ahmad A, Maier J, Follo M, Spitzmüller B, Wittmer A, Hellwig E, Hübner J, Jonas D. Food-borne enterococci integrate into oral biofilm:
an in vivo study. J Endod 36 (2010) 1812-9.
Hanin A, Sava I, Bao Y, Huebner J, Hartke A, Auffray Y, Sauvageot N. Screening of in vivo activated genes in Enterococcus faecalis during
insect and mouse infections and growth in urine. PLoS One 5 (2010) e11879.
Sava IG, Heikens E, Kropec AP, Theilacker C, Willems R, Huebner J. Enterococcal surface protein contributes to persistance in the host but
is not a target of opsonic and protective antibodies in Enterococcus faecium infection. J Med Microbiol 59 (2010) 1001-4.
Hoffmeister B, Peyerl-Hoffmann G, Pischke S, Zollner-Schwetz I, Krause R, Mueller M, Graf A, Kluge S, Burchard GD, Kern WV, Suttorp
N, Cramer JP. Differences in clinical manifestations of imported versus autochthonous leptospirosis in Austria and Germany. Am J Trop
Med Hyg 83 (2010) 326-35.
Jha S, Danelishvili L, Wagner D, Maser J, Li Y, Moric I, Vogt S, Yamazaki Y, Lai B, Bermudez L. Virulence-related Mycobacterium avium
MAV_2928 gene is associated with vacuole remodeling in macrophages. BMC Microbiol 10 (2010) 100.
Lange B, Vavra M, Kern WV, Wagner D. Indeterminate results of a tuberculosis-specific interferon-γ release assay in immunocompromised
patients. Eur Resp J 35 (2010) 1179-82.
Gening ML, Maira-Litrán T, Kropec A, Skurnik D, Grout M, Tsvetkov YE, Nifantiev NE, Pier GB. Synthetic {beta}-(1->6)-linked N-
acetylated and nonacetylated oligoglucosamines used to produce conjugate vaccines for bacterial pathogens. Infect Immun 78 (2010) 764-72.
Rieg SR, Bauer TM, Peyerl-Hoffmann G, Held J, Ritter W, Wagner D , Kern WV, Serr A. Paenibacillus larvae bacteremia in injection drug
users. Emerg Infect Dis 16 (2010) 487-9.
Rieg SR, Meier B, Fähnrich E, Huth A, Wagner D, Kern WV, Kalbacher H. Differential activity of innate defense antimicrobial peptides
against Nocardia species. BMC Microbiol 10 (2010) 61.
Li YJ, Danelishvili L, Wagner D, Petrofsky M, Bermudez LE. Identification of virulence determinants of Mycobacterium avium that impact
on the ability to resist host killing mechanisms. J Med Microbiol 59 (2010) 8-16.
2009
Zarb P, Amadeo B, Muller A, Drapier N, Vankerckhoven V, Davey P, Goossens H; on behalf of the ESAC-3 hospital care subproject group.
Identification of targets for quality improvement in antimicrobial prescribing: the web-based ESAC Point Prevalence Survey 2009. J
Antimicrob Chemother 65 (2010) 2247-52.
Martins A, Iversenc C, Rodrigues L, Spengler G, Ramosa J, Kern WV, Couto I, Viveiros M, Fanning S, Pagès JM, Amaral L. AcrAB
mediated MDR phenotype is maintained after efflux pump genes and their two regulators have restored wild type activities. Int J Antimicrob
Agents 34 (2009) 602-4.
Rodrigues L, Sampaio D, Couto I, Machado D, Kern WV, Amaral L, Viveiros M. The role played by efflux pumps in macrolide resistance in
Mycobacterium avium complex. Int J Antimicrob Agents 34 (2009) 529-33.
Rieg SR, Peyerl-Hoffmann G, de With K, Theilacker C, Wagner D, Hübner J, Dettenkofer M, Kaasch A, Seifert H, Schneider C, Kern WV.
Mortality of Staphylococcus aureus bacteremia and infectious diseases specialist consultation – a study of 521 patients in Germany. J Infect
59 (2009) 232-9.
Theilacker C, Jonas D, Huebner J, Bertz H, Kern WV. Outcomes of invasive infection due to vancomycin-resistant Enterococcus faecium
during a recent outbreak. Infection 37 (2009) 540-3.
Creti R, Fabretti F, Koch S, Huebner J, Garsin DA, Baldassarri L, Montanaro L, Arciola CR. Surface protein EF3314 contributes to virulence
properties of Enterococcus faecalis. Int J Artif Organs 32 (2009) 611-20.
Reuter S, Kern WV, Zenz C, Kern P. Prognostic factors for invasive aspergillosis in patients with haematological malignancies. Scand J
Infect Dis 41 (2009) 483-90.
de With K, Bestehorn H, Steib-Bauert M, Kern WV. Comparison of defined versus recommended versus prescribed daily doses for measuring
hospital antibiotic consumption. Infection 37 (2009) 349-52.
Sava IG, Zhang F, Toma I, Theilacker C, Li B, Baumert TF, Holst O, Linhardt RJ, Huebner J. Novel interactions of glycosaminoglycans and
bacterial glycolipids mediate binding of enterococci to human cells. J Biol Chem 284 (2009) 18194-201.
Theilacker C, Sanchez-Carballo P, Toma I, Fabretti F, Sava I, Kropec A, Holst O, Huebner J. Glycolipids are involved in biofilm
accumulation and prolonged bacteraemia in Enterococcus faecalis. Mol Microbiol 71 (2009) 1055-69.
Ammerlaan H, Seifert H, Harbarth S, Brun-Buisson C, Torres A, Antonelli M, Kluytmans J, Bonten M; European Practices of Infections
with Staphylococcus aureus (SEPIA) Study Group. Adequacy of antimicrobial treatment and outcome of Staphylococcus aureus bacteremia
in 9 Western European countries. Clin Infect Dis 49 (2009) 997-1005.
Coenen S, Muller A, Adriaenssens N, Vankerckhoven V, Hendrickx E, Goossens H; ESAC Project Group. European Surveillance of
Antimicrobial Consumption (ESAC). Outpatient parenteral antibiotic treatment in Europe. J Antimicrob Chemother 64 (2009) 200-5.
Rieg S, Huth A, Kalbacher H, Kern WV. Resistance against antimicrobial peptides is independent of Escherichia coli AcrAB, Pseudomonas
aeruginosa MexAB and Staphylococcus aureus NorA efflux pumps. Int J Antimicrob Agents 33 (2009) 174-6.
Wehmeier C, Schuster S, Fähnrich E, Kern WV, Bohnert JA. Site-directed mutagenesis reveals amino acid residues in the Escherichia coli
RND efflux pump AcrB that confer macrolide resistance. Antimicrob Agents Chemother 53 (2009) 329-30.
2008
van de Sande-Bruinsma N, Grundmann H, Verloo D, Tiemersma E, Monen J, Goossens H, Ferech M; European Antimicrobial Resistance
Surveillance System Group; European Surveillance of Antimicrobial Consumption Project Group. Antimicrobial drug use and resistance in
Europe. Emerg Infect Dis 14 (2008) 1722-30.
Wolkewitz M, Dettenkofer M, Bertz H, Schumacher M, Huebner J. Statistical epidemic modeling with hospital outbreak data. Stat Med 27
(2008) 6522-31.
Bohnert JA, Schuster S, Seeger MA, Fähnrich E, Pos KM, Kern WV. Site-directed mutagenesis reveals putative substrate binding residues in
the Escherichia coli RND efflux pump AcrB. J Bacteriol 190 (2008) 8225-9.
Henneke P, Dramsi S, Mancuso G, Chraibi K, Pellegrini E, Theilacker C, Hübner J, Santos-Sierra S, Teti G, Golenbock DT, Poyart C, Trieu-
Cuot P. Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis. J Immunol 180 (2008) 6149-58.
Arnold C, von Sanden S, Theilacker C, Blum HE. [Ulcerous colitis and infection with cytomegalovirus, herpes simplex virus and clostridium
difficile] Z Gastroenterol 46 (2008) 780-3.
Kern WV, Steib-Bauert M, Amann S, Fellhauer M, de With K. Hospital antibiotic management in Germany – results of the ABS maturity
survey of the ABS International group. Wiener Klin Wochenschr 120 (2008) 294-8.
Viveiros M, Martins A, Paixao L, Rodrigues L, Martins M, Couto I, Fähnrich E, Kern WV, Amaral L. Demonstration of intrinsic efflux
activity of Escherichia coli K-12 AG100 by an automated ethidium brmide method. Int J Antimicrob Agents 31 (2008) 458-62.
Linder K, Zia M, Kern WV, Pfau RKM, Wagner D. Relapses vs. reactions in multibacillary leprosy: proposal of new relapse criteria. Trop
Med Intern Health 13 (2008) 295-309.
Rodrigues L, Wagner D, Viveiros M, Sampaio D, Couto I, Vavra M, Kern WV, Amaral L. Thioridazine and chlorpromazine inhibition of
ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis. J Antimicrob Chemother 61 (2008) 1076-82.
Seifert H, Wisplinghoff H, Kaasch A, Achilles K, Langhorst A, Peyerl-Hoffmann G, Woehrmann A, Fätkenheuer G, Salzberger B, Kern
WV. [Epidemiology, course and prognosis of Staphylococcus aureus bacteremia--Preliminary results from the INSTINCT (INvasive
STaphylococcus aureus INfection CohorT) cohort]. Dtsch Med Wochenschr 133 (2008) 340-5.
Arciola CR, Baldassarri L, Campoccia D, Creti R, Pirini V, Huebner J, Montanaro L. Strong biofilm production, antibiotic multi-resistance
and high gelE expression in epidemic clones of Enterococcus faecalis from orthopaedic implant infections. Biomaterials 29 (2008) 580-6.
2007
Arciola CR, Campoccia D, Baldassarri L, Pirini V, Huebner J, Montanaro L. The role of Enterococcus faecalis in orthopaedic peri-implant
infections demonstrated by automated ribotyping and cluster analysis. Biomaterials 28 (2007) 3987-95.
Schumacher A, Trittler R, Bohnert JA, Kümmerer K, Pagès JM, Kern WV. Intracellular accumulation of linezolid in Escherichia coli,
Citrobacter freundii and Enterobacter aerogenes: role of enhanced efflux pump activity and inactivation. J Antimicrob Chemother 59 (2007)
1261-64.
Bohnert JA, Schuster S, Fähnrich E, Trittler R, Kern WV. Altered spectrum of multidrug resistance associated with a single point mutation in
the Escherichia coli RND type MDR efflux pump YhiV (MdtF). J Antimicrob Chemother 59 (2007) 1216-22.
Gabelmann A, Klein S, Kern WV, Krüger S, Brambs HJ, Rieber-Brambs A, Pauls S. Relevant imaging findings of cerebral aspergillosis on
MRI: a retrospective case-based study in immunocompromised patients. Eur J Neurol 14 (2007) 548-55.
Wichmann O, Gascon J, Schunk M, Puente S, Siikamaki H, Gjørup I, Lopez-Velez R, Clerinx J, Peyerl-Hoffmann G, Sundøy A, Genton B,
Kern P, Calleri G, de Górgolas M, Mühlberger N, Jelinek T; European Network on Surveillance of Imported Infectious Diseases. Severe
dengue virus infection in travelers: risk factors and laboratory indicators. J Infect Dis 195 (2007) 1089-96.
Coenen S, Ferech M, Haaijer-Ruskamp FM, Butler CC, Vander Stichele RH, Verheij TJ, Monnet DL, Little P, Goossens H, ESAC Project
Group. European Surveillance of Antimicrobial Consumption (ESAC): quality indicators for outpatient antibiotic use in Europe. Qual Saf
Health Care 16 (2007) 440-5.
Muller A, Coenen S, Monnet DL, Goossens H, ESAC Project Group. European Surveillance of Antimicrobial Consumption (ESAC):
outpatient antibiotic use in Europe, 1998-2005. Euro Surveill 12 (2007) E071011.1
Goossens H, Ferech M, Coenen S, Stephens P, ESAC Project Group. Comparison of outpatient systemic antibacterial use in 2004 in the
United States and 27 European countries. Clin Infect Dis 44 (2007) 1091-5. Erratum in: Clin Infect Dis 44 (2007) 1259.
2006
Theilacker C, Kacynski Z, Kropec A, Fabretti F, Sange T, Holst O, Huebner J. Opsonic antibodies to Enterococcus faecalis strain 12030 are
directed against lipoteichoic acid. Infect Immun 74 (2006) 5703-12.
Kern WV, de With K, Nink K, Steib-Bauert M, Schröder H. Regional variation in outpatient antibiotic prescribing in Germany. Infection 34
(2006) 269-73.
de With K, Steib-Bauert M, Straach P, Kern WV. Is there significant regional variation in hospital antibiotic consumption in Germany?
Infection 34 (2006) 274-7.
Ferech M, Coenen S, Malhotra-Kumar S, Dvorakova K, Hendrickx E, Suetens C, Goossens H, ESAC Project Group. European Surveillance
of Antimicrobial Consumption (ESAC): outpatient quinolone use in Europe. J Antimicrob Chemother 58 (2006) 423-7.
Coenen S, Ferech M, Malhotra-Kumar S, Hendrickx E, Suetens C, Goossens H, ESAC Project Group. European Surveillance of
Antimicrobial Consumption (ESAC): outpatient macrolide, lincosamide and streptogramin (MLS) use in Europe. J Antimicrob Chemother
58 (2006) 418-22.
Coenen S, Ferech M, Dvorakova K, Hendrickx E, Suetens C, Goossens H, ESAC Project Group. European Surveillance of Antimicrobial
Consumption (ESAC): outpatient cephalosporin use in Europe. J Antimicrob Chemother 58 (2006) 413-7.
Ferech M, Coenen S, Dvorakova K, Hendrickx E, Suetens C, Goossens H, ESAC Project Group. European Surveillance of Antimicrobial
Consumption (ESAC): outpatient penicillin use in Europe. J Antimicrob Chemother 58 (2006) 408-12.
Ferech M, Coenen S, Malhotra-Kumar S, Dvorakova K, Hendrickx E, Suetens C, Goossens H, ESAC Project Group. European Surveillance
of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe. J Antimicrob Chemother 58 (2006) 401-7.
Meyer-Koenig U, Romberg I, Schneider K, Weidmann M, Kern WV, Hufert FT. Diagnostic value of cytomegalovirus pp67 RT-PCR in solid
organ transplant recipients. J Clin Microbiol 44 (2006) 3394-6.
de With K, Meyer E, Steib-Bauert M, Schwab F, Daschner FD, Kern WV. Antibiotic use in two cohorts of German intensive care units,
2001-2002. J Hosp Infect 64 (2006) 231-7.
von Baum H, Sigge A, Bommer M, Kern WV, Marre R, Doehner H, Kern P, Reuter S. Moxifloxacin prophylaxis in neutropenic patients. J
Antimicrob Chemother 58 (2006) 891-4.
Hsu CT, Ganong AL, Reinap B, Mourelatos Z, Huebner J, Wang J. Immunochemical characterization of polysaccharide antigens from six
clinical strains of enterococci. BMC Microbiol 6 (2006) 62.
Creti R, Koch S, Fabretti F, Baldassarri L, Huebner J. Enterococcal colonization of the gastro-intestinal tract: role of biofilm and
environmental oligosaccharides. BMC Microbiol 6 (2006) 60.
Fabretti F, Theilacker C, Baldassarri L, Kaczynski Z, Kropec A, Holst O, Huebner J. Alanine esters of enterococcal lipoteichoic acid play a
role in biofilm formation and resistance to antimicrobial peptides. Infect Immun 74 (2006) 4164-71.
Fang X, Zeisel MB, Wilpert J, Gissler B, Thimme R, Kreutz C, Maiwald T, Timmer J, Kern WV, Donauer J, Geyer M, Walz G, Depla E,
von Weizsäcker F, Blum HE, Baumert TF. Host cell responses induced by hepatitis C virus binding. Hepatology 43 (2006) 1326-36.
Huck B, Egger M, Bertz H, Peyerl-Hoffmann G, Kern WV, Neumann-Haefelin D, Falcone V. Human metapneumovirus (HMPV) infection
in a hematopoietic stem cell transplant recipient with relapsed multiple myeloma and rapidly progressing lung cancer. J Clin Microbiol 44
(2006) 2300-3.
de With K, Maier L, Steib-Bauert M, Kern P, Kern WV. Trends in antibiotic use at a university hospital: defined or prescribed daily doses,
patient days or admissions as denominator? Infection 34 (2006) 91-4.
Wagner D, Maser J, Moric I, Vogt S, Kern WV, Bermudez LE. Elemental analysis of the Mycobacterium avium–containing phagosomes in
macrophages from Balb/c mice. Biochem Biophys Res Comm 344 (2006) 1346-51.
Pannek S, Higgins PG, Steinke P, Jonas D, Akova M, Bohnert JA, Seifert H, Kern WV. Multidrug efflux inhibition in Acinetobacter
baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginin-ß-naphthylamide. J Antimicrob Chemother 57 (2006)
970-4.
Hufnagel M, Carey VJ, Baldassarri L, Reinert RR, Huebner J. Distribution of four capsular serotypes of Enterococcus faecalis among
clinical isolates from different geographical origins and infection sites. Infection 34 (2006) 1-4.
Kern WV, Steinke P, Schumacher A, Schuster S, von Baum H, Bohnert JA. Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative
efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Escherichia coli. J Antimicrob Chemother 57 (2006) 339-43.
Schuhmacher A, Steinke P, Bohnert JA, Akova M, Jonas D, Steib-Bauert M, de With K, Reuter S, Bertz H, Frank U, Kern WV. Effect of 1-
(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor on antimicrobial drug susceptibility in clinical isolates of
Enterobacteriaceae other than E. coli. J Antimicrob Chemother 57 (2006) 344-8.
Jansen JP, Kern WV, Cornely OA, Karthaus M, Ruhnke M, Ullmann AJ, Resch A. Economic evaluation of voriconazole versus conventional
amphotericin B in the treatment of invasive aspergillosis in Germany. Value Health 9 (2006) 12-23.
Viscoli C, Cometta A, Kern WV, Bock R, Paesmans M, Crokaert F, Glauser MP, Calandra T; International Antimicrobial Therapy Group of
the EORTC. Piperacillin-tazobactam monotherapy in high-risk febrile and neutropenic cancer patients. Clin Microbiol Infect 12 (2006) 212-
6.
2005
Kern WV, Steib-Bauert M, de With K, Reuter S, Bertz H, Frank U, von Baum H. Fluoroquinolone consumption and resistance in
haematology-oncology patients – ecological analysis in two university hospitals 1999-2002. J Antimicrob Chemother 55 (2005) 57-60.
Wagner D, Maser J, Lai B, Cai Z, Barry CE, Höner zu Bentrup K, Russell DG, Bermudez LE. Elemental analysis of Mycobacterium avium,
Mycobacterium tuberculosis and Mycobacterium smegmatis – containing phagosomes indicates pathogen-induced microenvironments within
the host cell’s endosomal system. J Immunol 174 (2005) 1491-500.
Bohnert J, Kern WV. Selected arylpiperazines are capable of reversing multidrug resistance in Escherichia coli overexpressing RND efflux
pumps. Antimicrob Agents Chemother 49 (2005) 849-52.
Goossens H, Ferech M, Vander Stichele RH, Elseviers M, and the ESAC Project Group. Outpatient antibiotic use in Europe and association
with resistance: a cross-national database study. Lancet 365 (2005) 579-87.
Kern WV, Klose K, Jellen-Ritter AS, Oethinger M, Bohnert J, Kern P, Reuter S, von Baum H, Marre R. Fluoroquinolone resistance of
Escherichia coli at a cancer center: epidemiologic evolution and effects of discontinuing prophylactic fluoroquinolone use in neutropenuc
patients with leukemia. Eur J Clin Microbiol Infect Dis 24 (2005) 111-8.
de With K, Steib-Bauert M, Knoth H, Dörje F, Strehl E, Rothe U, Maier L, Kern WV. Hospital use of systemic antifungal drugs. BMC Clin
Pharmacol 5 (2005) 1.
Reuter S, Kern WV, Sigge A, Döhner H, Marre R, Kern P, von Baum H. Impact of fluoroquinolone prophylaxis on reduced infection-related
mortality in neutropenic patients with hematologic malignancies. Clin Infect Dis 40 (2005) 1087-93.
Wagner D, Sangari FJ, Parker A, Bermudez LE. fecB, a gene potentially involved in iron transport in Mycobacterium avium, is not induced
within macrophages. FEMS Microbiol Letters 247 (2005) 185-91.
Weitzel T, Muhlberger N, Jelinek T, Schunk M, Ehrhardt S, Bogdan C, Arasteh K, Schneider T, Kern WV, Fatkenheuer G, Boecken G,
Zoller T, Probst M, Peters M, Weinke T, Gfrorer S, Klinker H, Holthoff-Stich ML; SIMPID Network. Imported leishmaniasis in Germany
2001-2004: data of the SIMPID surveillance network. Eur J Clin Microbiol Infect Dis 24 (2005) 471-6.
Maira-Litran T, Kropec A, Goldmann DA, Pier GB. Comparative opsonic and protective activities of Staphylococcus aureus conjugate
vaccines containing native or deacetylated staphylococcal poly-N-acetyl-beta-(1-6)-glucosamine. Infect Immun 73 (2005) 6752-62.
Kropec A, Maira-Litran T, Jefferson KK, Grout M, Cramton SE, Gotz F, Goldmann DA, Pier GB. Poly-N-acetylglucosamine production in
Staphylococcus aureus is essential for virulence in murine models of systemic infection. Infect Immun 73 (2005) 6868-76.
Hufnagel M, Kropec A, Theilacker C, Huebner J. Naturally acquired antibodies against four Enterococcus faecalis capsular polysaccharides
in healthy human sera. Clin Diagn Lab Immunol 12 (2005) 930-4.
Baldassarri L, Bertuccini L, Creti R, Filippini P, Ammendolia MG, Koch S, Huebner J, Orefici G. Glycosaminoglycans mediate invasion and
survival of Enterococcus faecalis into macrophages. J Infect Dis 191 (2005) 1253-62.
Wagner D, Sander A, Bertz H, Finke J, Kern WV. Breakthrough invasive infection due to Debaryomyces hansenii (teleomorph Candida
famata) and Scopulariopsis brevicaulis in a stem cell transplant patient receiving liposomal amphotericin B and caspofungin for suspected
aspergillosis. Infection 33 (2005) 397-400.
Kern WV, de With K, Steib-Bauert M, Fellhauer M, Plangger A, Probst W, and the MABUSE-INTERREGIO-II project team. Antibiotic use
in non-university regional acute care general hospitals in southwestern Germany, 2001-2002. Infection 33 (2005) 333-9.
Engel A, Knoll SA, Kern P, Kern WV. Interleukin-8 serum levels at fever onset in patients with neutropenia predict early medical
complications. Infection 33 (2005) 380-382.
Hufnagel M, Huebner J. Analysis of the specific immune response against capsular polysaccharides of two patients with systemic
enterococcal infections. Infection 33 (2005) 373-6.
Kropec A, Hufnagel M, Zimmermann K, Huebner J. in vitro assessment of the host response against Enterococcus faecalis used in probiotic
preparations. Infection 33 (2005) 377-9.
Gascon J, Mayor A, Muhlberger N, Peyerl-Hoffmann G, Oliveira I, Dobano C, Jelinek T, Corachan M. [Molecular epidemiological
surveillance of markers for antimalarial drugs in Plasmodium falciparum isolates imported to Barcelona, Spain]
Med Clin (Barc) 125 (2005) 286-9.
2004
Buchheidt D, Hummel M, Schleiermacher D, Spiess B, Schwerdtfeger R, Cornely OA, Wilhelm S, Reuter S, Kern WV, Südhoff T, Mörz H,
Hehlmann R. Prospective clinical evaluation of a LightCycler-mediated polymerase chain reaction assay, a nested-PCR assay and a
galactomannan enzyme-linked immunosorbent assay for detection of invasive aspergillosis in neutropenic cancer patients and
haematological stem cell transplant recipients. Br J Haematol 125 (2004) 196-202.
de With K, Bergner J, Bühner R, Dörje F, Gonnermann C, Haber M, Hartmann M, Rothe U, Strehl E, Steib-Bauert M, Kern WV.
Antibiotikaanwendung an deutschen Hochschulkliniken (Projekt INTERUNI-II). Ergebnisse für medizinische Kliniken unter
Berücksichtigung von Intensivpflegestationen, onkologischen Stationen und sonstigen Pflegebereichen. Med Klin 99 (2004) 347-54.
de With K, Bergner J, Bühner R, Dörje F, Gonnermann C, Haber M, Hartmann M, Rothe U, Strehl E, Steib-Bauert M, Kern WV. Antibiotic
use in German university hospitals 1998-2000 (project INTERUNI-II). Int J Antimicrob Agents 24 (2004) 213-8.
Harder J, Riecken B, Walter E, Ihling K, Bauer TM. Hepatitis C virus infection in intravenous drug users. Clin Microbiol Infect (2004) 768-
70.
McGarvey JA, Wagner D, Bermudez LE. Differential gene expression in mononuclear phagocytes infected with pathogenic and non-
pathogenic mycobacteria. Clin Exp Immunol 136 (2004) 490-500.
Kern WV, de With K, Gonnermann C, Strehl E, and the MABUSE-INTERUNI-II project team. Update on glycopeptide use in German
university hospitals. Infection 32 (2004) 157-62.
Wagner D, de With K, Huzly D, Hufert F, Weidmann M, Breisinger S, Eppinger S, Kern WV, Bauer TM. Nosocomial acquisition of
Dengue. Emerg Infect Dis 10 (2004) 1872-3.
Kern WV, de With K. Antibiotikaanwendung auf chirurgischen und internistischen Intensivstationen von Universitätskliniken – Ergebnisse
des Projekts INTERUNI-II. Krankenhaushygiene + Infektionsverhütung 26 (2004) 215-7.
vander Stichele RH, Elseviers M, Ferech M, Blot S, Goossens H, and the ESAC Project Group. European Surveillance of Antimicrobial
Consumption (ESAC): data collection performance and methodological approach. Br J Clin Pharmacol 58 (2004) 1-10.
de With K, Steib-Bauert M, Bergner J, Bühner R, Dörje F, Gonnermann C, Haber M, Hartmann M, Rothe U, Strehl E, Daschner FD, Kern
WV. Antibiotikaanwendung an chirurgischen Universitätskliniken (Projekt INTERUNI-II). Krankenhauspharmazie 25 (2004) 478-83.
Wichmann O, Muehlberger N, Jelinek T, Alifrangis M, Peyerl-Hoffmann G, Muhlen M, Grobusch MP, Gascon J, Matteelli A, Laferl H,
Bisoffi Z, Ehrhardt S, Cuadros J, Hatz C, Gjorup I, McWhinney P, Beran J, da Cunha S, Schulze M, Kollaritsch H, Kern P, Fry G, Richter J;
European Network on Surveillance of Imported Infectious Diseases. Screening for mutations related to atovaquone/proguanil resistance in
treatment failures and other imported isolates of Plasmodium falciparum in Europe. J Infect Dis 190 (2004) 1541-6.
2003
Cometta A, Kern WV, De Bock R, Paesmans B, Vandenbergh M, Marchetti O, Akan H, Vandercam B, Skoutelis A, Akova M, Korten V,
Crokaert F, Engelhard D, Gaya H, Padmos A, Calandra T, Klasresky J, Zinner S, Glauser M, Viscoli C, for the EORTC International
Antimicrobial Therapy Group: Vancomycin versus placebo for persistent fever in neutropenic cancer patients given piperacillin/tazobactam
monotherapy: an EORTC-IATG multicenter, double blind, placebo-controlled trial. Clin Infect Dis (2003) 328-89.
Wellinghausen N, Kern WV, Haase G, Rozdzinski E, Kern P, Marre R, Essig A, Hetzel J, Hetzel M. A farmer with recurrent fever and
bilateral pulmonary infiltrates. Int J Med Microbiol 293 (2003) 441-5.
2002
Bauer TM, Fernandez J, Navasa M, Vila J, Rodes J. Failure of Lactobacillus spp. to prevent bacterial translocation in a rat model of
experimental cirrhosis. J Hepatol 36 (2002) 501-6.
Bauer TM, Follo A, Navasa M, Vila J, Planas R, Clemente G, Vargas V, Bory F, Vaquer P, Rodes J. Daily norfloxacin is more effective than
weekly rufloxacin in prevention of spontaneous bacterial peritonitis recurrence. Dig Dis Sci 47 (2002) 1356-61.
Bauer TM, Schwacha H, Steinbruckner B, Brinkmann FE, Ditzen AK, Aponte JJ, Pelz K, Berger D, Kist M, Blum HE. Small intestinal
bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia. Am J Gastroenterol 97 (2002) 2364-70.
Broxmeyer L, Sosnowska D, Miltner E, Chacon O, Wagner D, McGarvey J, Barletta RG, Bermudez LE. Killing of Mycobacterium avium
and Mycobacterium tuberculosis by a mycobacteriophage delivered by a nonvirulent mycobacterium: a model for phage therapy of
intracellular bacterial pathogens. J Infect Dis 186 (2002) 1155-60.
Herbrecht R, Denning DW, Patterson TF, Bennett Je, Greene RE, Oestmann JW, Kern WV, Marr KA, Ribaud P, Lortholary O, Sylvester R,
Rubin RH, Wingard JR, Stark P, Durand C, Caillot D, Thiel E, Chandrasekar PH, Hodges MR, Schlamm HT, Troke PF, De Pauw B.
Randomized comparison of voriconazole and amphotericin B in primary therapy of invasive aspergillosis. N Engl J Med 347 (2002) 408-15.
Kern WV, de With K, Trautmann M, Kern P, Gonnermann C. Glycopeptide use at four university hospitals in southern Germany. Infection
30 (2002) 262-6.
Wagner D, Sangari FJ, Kim S, Petrofsky M, Bermudez LE. Mycobacterium avium infection of macrophages results in progressive
suppression of interleukin-12 production in vitro and in vivo. J Leukoc Biol 71 (2002) 80-8.
Wellinghausen N, Pietzcker T, Kern WV, Essig A, Marre R. Expanded spectrum of Nocardia species causing clinical nocardiosis detected
by molecular methods. Int J Med Microbiol 292 (2002) 277-82.
Wellinghausen N, Sing A, Kern WV, Perner S, Marre R, Rentschler J. A fatal case of necrotizing sinusitis due to toxigenic Corynebacterium
ulcerans. Int J Med Microbiol 292 (2002) 59-63.
Übersichten, Monographien, Buchbeiträge, Letters/short reports, Journal supplement-Arbeiten
2017
Lehmann C, Berner R, Bogner JR, Cornely OA, de With K, Herold S, Kern WV, Lemmen S, Pletz MW, Ruf B, Salzberger B, Stellbrink HJ,
Suttorp N, Ullmann AJ, Fätkenheuer G, Jung N. The "Choosing Wisely" initiative in infectious diseases. Infection 2017 Mar 13. [Epub ahead
of print]
Abele-Horn M, Kern WV, Liese J. Engpässe bei Antibiotika: Alternativen für die 1. Wahl. Dtsch Ärztebl 2017; 114: A-416.
Poppert S, Heideking M, Agostini H, Fritzenwanker M, Wüppenhorst N, Muntau B, Henneke P, Kern WV, Krücken J, Junker B, Hufnagel
M. Diffuse unilateral subacute neuroretinitis caused by Ancylostoma hookworm. Emerg Infect Dis 2017 [in press]
van Ingen J, Wagner D, Gallagher J, Morimoto K, Lange C, Haworth CS, Floto RA, Adjemian J, Prevots DR, Griffith DE; NTM-NET. Poor
adherence to management guidelines in nontuberculous mycobacterial pulmonary diseases. Eur Respir J 2017; 49: pii: 160185.
de With K, Wilke K, Först G, Kramme E, Kern WV. [Hospital Antibiotic Stewardship - New Guidelines and New Findings]. Dtsch Med
Wochenschr 2017; 142:177-82.
2016
Möbes M, Pfaff L, Usadel S, Technau-Hafsi K. Crusted papulopustular lesions, plaques and ulcers. J Dtsch Dermatol Ges 2016 Dec 30
[Epub ahead of print]
Grohmann E, Goessweiner-Mohr N, Brantl S. DNA-binding proteins regulating pIP501 transfer and replication. Front Mol Biosci 2016;
3:42.
Jung N, Berner R, Bogner JR, Cornely OA, de With K, Herold S, Kern WV, Lemmen S, Pletz MW, Ruf B, Salzberger B, Stellbrink HJ,
Suttorp N, Ullmann A, Fätkenheuer G. Klug entscheiden …. in der Infektiologie. Dtsch Ärztebl 2016; 113:A608-10.
Probst I, Vaishampayan A, Küchler V, Grohmann E, Antimikrobielle Oberflächenbeschichtung tötet multiresistente Krankehitserreger –
selbst regerierende, mikrogalvanische Zellen produzieren reaktive Sauerstoffspezies. Flug Reisemed 2016; 23:217-20.
Lübbert C, Vogelmann R, Salzberger B, Kern WV. Optionen zur optimierten Therapie der Helicobacter pylori-Infektion. Z Gastroenterol
2016; 54:1170-1.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2015 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer-Verlag, Berlin Heidelberg New York 2016, pp. 273-92.
Borde JP, Sitaru G, Kopp WH, Ruhparwar A, Ehlermann P, Lasitschka F, Dalpke A, Heininger A. Heart transplantation as salvage therapy
for progressive prosthetic valve endocarditis due to methicillin-resistant Staphylococcus epidermidis (MRSE). J Cardiothorac Surg 2016 ;
11:100
Held J, Schweizer H, Zange S, Kern WV, Wagner D. Pneumonia and pyogenic skin abscesses in a 79-year-old man. J Clin Microbiol 2016
(accepted)
de With K, Allerberger F, Amann S, Apfalter P, Brodt HR, Eckmanns T, Fellhauer M, Geiss HK, Janata O, Krause R, Lemmen S, Meyer E,
Mittermayer H, Porsche U, Presterl E, Reuter S, Sinha B, Strauß R, Wechsler-Fördös A, Wenisch C, Kern WV. Strategies to enhance
rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases. Infection 2016; 44:395-439.
Rieg S, Küpper MF. Infectious diseases consultations can make the difference: a brief review and a plea for more infectious diseases
specialists in Germany. Infection. 2016 Apr;44(2):159-66
Lange B, Stete K, Bozorgmehr K, Camp J, Kranzer K, Kern WV, Rieg S. [Health care of refugees - A short review with focus on infectious
diseases]. Dtsch Med Wochenschr 2016; 141:772-6.
Kern WV. Therapie bei rezidivierendem Erysipel ohne erkennbare Ursache. tägl prax 2016; 57:352.
Borde JP, Först G, Kern WV. Entwicklung Antibiotic Stewardship-spezifischer Qualitätsindikatoren. Krankenhaushygiene up2date 11
(2016) 103-13.
Gastmeier P, Geffers C, Herrmann M, Lemmen S, Salzberger B, Seifert H, Kern WV, Fätkenheuer G. Nosokomiale Infektionen und
Infektionen mit multiresistenten Erregern – Häufigkeit und Sterblichkeit. Dtsch Med Wochenschr 2016; 141:421-6.
Fätkenheuer G, Kern WV, Salzberger B. An urgent call for infectious disease specialists. Infection 2016; 44:269-70.
Ewig S, Höffken G, Kern WV, Rohde G, Flick H, Krause R, Ott S, Bauer T, Dalhoff K, Gatermann S, Kolditz M, Krüger S, Lorenz J, Pletz
M, de Roux A, Schaaf B, Schaberg T, Schütte H, Welte T. [Management of Adult Community-acquired Pneumonia and Prevention - Update
2016]. Pneumologie 2016; 70:151-200.
2015
Rieg S. [Endocarditis - an update]. Dtsch Med Wochenschr 2015; 140:1817-20.
Kern WV, Fätkenheuer G, Tacconelli E, Ullmann A. Klinische Infektiologie in Deutschland und Europa. Z Evid Fortbild Qual Gesundhwes
2015; 109:493-9.
Thern J, Kern WV. Zur Diskussion: Qualitätsindikatoren Antibiotikaverschreibung und Infektionsmedizin. Z Evid Fortbild Qual
Gesundhwes 2015; 109:511-4.
Christoph A, Ehm C, de With K. Auswirkungen der ABS-Fortbildungsinitiative auf die ABS-Strukturqualität teilnehmender Krankenhäuser.
Z Evid Fortbild Qual Gesundhwes 2015; 109:521-7.
Kern WV. Usefulness of the CPG in the management of severe S. aureus infections. Enferm Infecc Microbiol Clin 2015; 33:577-8.
Steib-Bauert M, Först G. Nationales Surveillanceprojekt zum Antibiotikaverbrauch in deutschen Allgemeinkrankenhäusern - das ADKA-if-
RKI-Projekt. Z Evid Fortbild Qual Gesundhwes 2015; 109:542-3.
Rieg S, Küpper MF. [Impact of infectious diseases specialist consultations on quality of care and patient survival]. Z Evid Fortbild Qual
Gesundhwes 2015; 109:500-10.
Kern WV. [New antibacterial agents on the market and in the pipeline]. Internist (Berl) 2015; 56:1255-63.
Weis S, Kaasch AJ, Rieg S, Löffler B, Hagel S, Forstner C, Brunkhorst FM, Pletz MW. [Staphylococcus aureus bacteremia - a distinct
entity]. Dtsch Med Wochenschr 2015; 140:982-9.
Held J, Gräber K, Leubner-Metzger G, Kunkel T, Theilacker C, Kramme S, Schmitt-Graeff A. Photo quiz: mysterious objects in a pleural
biopsy sample from a patient with recurrent pleural empyema. J Clin Microbiol 2015; 53: 2005 + 2393.
Borde JP, Ruhnke M, Küpper MF, Hübner J, Kern WV. [How to do: Blood culture]. Dtsch Med Wochenschr 2015; 140:666-9.
Kern WV. [Community acquired pneumonia: antibiotic monotherapy is not inferior to combination therapy]. Dtsch Med Wochenschr 2015;
140:964.
Hagel S, Epple HJ, Feurle GE, Kern WV, Lynen Jansen P, Malfertheiner P, Marth T, Meyer E, Mielke M, Moos V, von Müller L,
Nattermann J, Nothacker M, Pox C, Reisinger E, Salzberger B, Salzer HJ, Weber M, Weinke T, Suerbaum S, Lohse AW, Stallmach A. [S2k-
guideline gastrointestinal infectious diseases and Whipple's disease]. Z Gastroenterol 2015; 53:418-59.
Schöfer H, Weberschock T, Bräuninger W, Bremer V, Dreher A, Enders M, Esser S, Hamouda O, Hagedorn HJ, Handrick W, Krause W,
Mayr C, Münstermann D, Nast A, Ochsendorf F, Petry U, Potthoff A, Prange H, Rieg S, Schneede P, Sing A, Weber J, Wichelhaus TA,
Brockmeyer N. S2k guideline* "Diagnosis and therapy of syphilis" - short version. J Dtsch Dermatol Ges 2015;13:472-80.
López-Varela E, García-Basteiro AL, Santiago B, Wagner D, van Ingen J, Kampmann B. Non-tuberculous mycobacteria in children:
muddying the waters of tuberculosis diagnosis. Lancet Respir Med 2015; 3:244-56.
Fätkenheuer G, Cornely OA, Kern WV, Salzberger B, Stallmach A, Welte T. [Perspectives of infectious diseases in Germany]. Dtsch Med
Wochenschr 2015; 140:210-2.
Lenz D, Held J, Goerke S, Wagner D, Tintelnot K, Henneke P, Hufnagel M. Primary cutaneous cryptococcosis in an eight-year-old
immunocompetent child: how to treat? Klin Padiatr 2015; 227:41-4.
Müller J, Voss A, Köck R, Sinha B, Rossen JW, Kaase M, Mielke M, Daniels-Haardt I, Jurke A, Hendrix R, Kluytmans JA, Kluytmans-van
den Bergh MF, Pulz M, Herrmann J, Kern WV, Wendt C, Friedrich AW. Cross-border comparison of the Dutch and German guidelines on
multidrug-resistant Gram-negative microorganisms. Antimicrob Resist Infect Control 2015; 4:7.
Küpper MF, Stellbrink HJ, Kern WV, Müller MC. [Postexposure prophylaxis in daily clinical practice]. Dtsch Med Wochenschr 2015 ;
140:485-8.
Lübbert C, Hau HM, Rodloff A, Mössner J, Mischnik A, Bercker S, Bartels M, Kaisers UX. [Clinical impact of infections with carbapenem-
resistant enterobacteriaceae in liver transplant recipients]. Z Gastroenterol 2015; 53:1276-87
Mischnik A, Kaase M, Lübbert C, Seifert H, Kern WV. [Carbapenem-resistance in Enterobacteriaceae, Pseudomonas aeruginosa and
Acinetobacter baumannii]. Dtsch Med Wochenschr. 2015; 140:172-6
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2014 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer-Verlag, Berlin Heidelberg New York 2015, pp. 303-30.
Kern WV. Antibacterial Agents. In: Maschmeyer G, Rolston KVI (eds.) Infections in Hematology. Springer-Verlag Berlin Heidelberg 2015,
pp. 229-58.
Orasch C, Averbuch D, Mikulska M, Cordonnier C, Livermore DM, Gyssens IC, Klyasova G, Engelhard D, Kern WV, Viscoli C, Akova M,
Marchetti O, for the 4th European Conference on Infections in Leukemia (ECIL-4). Discontinuation of empirical antibiotic therapy in
neutropenic leukaemia patients with fever of unknown origin is ethical. Clin Microbiol Infect 2015; 21: e25–e27.
2014
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2013 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer-Verlag, Berlin Heidelberg New York 2014, pp. 303-30.
Jendrossek S, Wagner D, Henneke P, Warnatz K, Voll R, Ehl S. Immunologische Grundlagen der Entzündungsreaktion. Zahnärztliche
Mitteilungen 2014; 24, 28-31.
Kern WV. Antibiotic Stewardship - Strategien zur Sicherung eines intelligenten und rationalen Antibiotikaeinsatzes. Drug Res (Stuttg) 2014
Nov; 64 Suppl 1:S5
Lange B, Neumann S, Hirsch HH, Kern WV. [Prevention of infections in immune deficiency]. Dtsch Med Wochenschr 139 (2014) 1999-
2002.
Theilacker C, Kern WV. Diabetes und Impfen - was ist durch die eingeschränkte Immunogenität zu beachten? klinikarzt 43 (2014) 450-5.
Zeidan R, Telschow C, Schröder H, Kern WV. Antibiotikaverbrauch im ambulanten Bereich. In: BVL, PEG, if (Hrsg.) GERMAP2012
Antibiotika-Resistenz und -Verbrauch. Antiinfectives Intelligence, Rheinbach 2014, pp. 11-6.
Kern WV, de With K, Steib-Bauert M. Antibiotikaverbrauch im stationären Bereich. In: BVL, PEG, if (Hrsg.) GERMAP2012 Antibiotika-
Resistenz und -Verbrauch. Antiinfectives Intelligence, Rheinbach 2014, pp. 23-7.
Kern WV,Schulz M, Mangiapane S. Antibiotikaverschreibung im ambulanten Setting – welche Qualitätsindikatoren sind geeignet ? In: BVL,
PEG, if (Hrsg.) GERMAP2012 Antibiotika-Resistenz und -Verbrauch. Antiinfectives Intelligence, Rheinbach 2014, pp. 23-7.
Thern J, de With K, Strauß R, Kern WV. Qualitätsindikatoren und Antibiotikaverordnung im Akutkrankenhaus. In: BVL, PEG, if (Hrsg.)
GERMAP2012 Antibiotika-Resistenz und -Verbrauch. Antiinfectives Intelligence, Rheinbach 2014, pp. 28-32.
Tacconelli E, Kern WV. New antibiotics for skin and skin-structure infections. Lancet Infect Dis 2014 Jun 5 [Epub ahead of print]
Lange C, Abubakar I, Alffenaar JW, Bothamley G, Caminero JA, Carvalho AC, Chang KC, Codecasa L, Correia A, Crudu V, Davies P,
Dedicoat M, Drobniewski F, Duarte R, Ehlers C, Erkens C, Goletti D, Günther G, Ibraim E, Kampmann B, Kuksa L, de Lange W, van Leth
F, van Lunzen J, Matteelli A, Menzies D, Monedero I, Richter E, Rüsch-Gerdes S, Sandgren A, Scardigli A, Skrahina A, Tortoli E,
Volchenkov G, Wagner D, van der Werf MJ, Williams B, Yew WW, Zellweger JP, Cirillo DM; TBNET. Management of patients with
multidrug-resistant/extensively drug-resistant tuberculosis in Europe: a TBNET consensus statement. Eur Respir J 44 (2014) 23-63.
Bremer V, Brockmeyer NH, Hagedorn HJ, Hartmann M, Hörauf A, Kern WV, Kohl PK, Köhler E, Köhn FM, Kresken M, Mayr C, Meyer T,
Möst J, Mylonas I, Nitschke H, Petry KU, Plettenberg A, Potthoff A, Rieg S, Spornraft-Ragaller P, Rasokat H, Schöfer H, Schneede P,
Throm W, Walter G, Weidner W, Wichelhaus TA. Gonorrhoe bei Erwachsenen und Adoleszenten. GMS Infect Dis 2014; 2:1-17
Panning M, Huzly D, Hengel H, Kern WV, Dettenkofer M. Entscheidende Rolle molekularer Diagnostik. Dtsch Ärztebl 2014; 111:14.
2013
de With K, Allerberger F, Amann S, et al. Strategien zur Sicherung rationaler Antibiotika-Anwendung im Krankenhaus - AWMF-
Registernummer 092/001. http://www.awmf.org/uploads/tx_szleitlinien/092-001l_S3_Antibiotika_Anwendung_im_Krankenhaus_2013-
12.pdfGoessweiner-Mohr N, Arends K, Keller W, Grohmann E. Conjugative type IV secretion systems in Gram-positive bacteria. Plasmid
2013; 70:289-302.
Averbuch D, Cordonnier C, Livermore DM, Mikulska M, Orasch C, Viscoli C, Gyssens IC, Kern WV, Klyasova G, Marchetti O, Engelhard
D, Akova M; ECIL4, a joint venture of EBMT, EORTC, ICHS, ESGICH/ESCMID and ELN. Targeted therapy against multi-resistant
bacteria in leukemic and hematopoietic stem cell transplant recipients: guidelines of the 4th European Conference on Infections in Leukemia
(ECIL-4, 2011). Haematologica 2013; 98:1836-47.
Averbuch D, Orasch C, Cordonnier C, Livermore DM, Mikulska M, Viscoli C, Gyssens IC, Kern WV, Klyasova G, Marchetti O, Engelhard
D, Akova M; ECIL4, a joint venture of EBMT, EORTC, ICHS, ESGICH/ESCMID and ELN. European guidelines for empirical antibacterial
therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European Conference on Infections in
Leukemia. Haematologica 2013; 98:1826-35.
Gyssens IC, Kern WV, Livermore DM; ECIL-4, a joint venture of EBMT, EORTC, ICHS and ESGICH of ESCMID. The role of antibiotic
stewardship in limiting antibacterial resistance among hematology patients. Haematologica 2013; 98:1821-5.
Berner R, Duppenthaler A, Kern WV, Tenenbaum T. Antimikrobielle Chemotherapie. In: DGPI (Hrsg.) DGPI Handbuch – Infektionen bei
Kindern und Jugendlichen. Thiem Verlag, Stuttgart 2013, pp. 77-97.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2013 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer-Verlag, Berlin Heidelberg New York 2013, pp. 303-30.
Kern WV. [Disputed therapy recommendations for infectious endocarditis.] Internist (Berl) 2013 Jul 31. [Epub ahead of print]
Pletz MW, van der Linden M, Fobiwe JP, Theilacker C. [Pneumococcal vaccination in adults: background of the current discussion]. Dtsch
Med Wochenschr 138 (2013) 185-7.
Otto C, Huzly D, Kemna L, Hüttel A, Benk C, Rieg S, Ploenes T, Werner M, Kayser G. Acute fibrinous and organizing pneumonia
associated with influenza A/H1N1 pneumonia after lung transplantation. BMC Pulm Med 13 (2013) 30.
Theilacker C, Kern WV. [Prevention of sepsis after splenectomy]. Dtsch Med Wochenschr 138 (2013) 1729-33.
Schweickert B, Kern WV, de With K, Meyer E, Berner R, Kresken M, Fellhauer M, Abele-Horn M, Eckmanns T. [Surveillance of antibiotic
consumption : Clarification of the "definition of data on the nature and extent of antibiotic consumption in hospitals according to § 23
paragraph 4 sentence 2 of the IfSG"]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56 (2013) 903-12.
Stocker H, Kern WV. [Colistin : Renaissance of an old antibiotic?] Internist (Berl) 54 (2013) 936-44.
Battegay M, Fätkenheuer G, Kern WV. [Clinical infectious diseases : interdisciplinary and unique.] Internist (Berl) 54 (2013) 909-10.
Graef S, Kurth A, Auw-Haedrich C, Plange N, Kern WV, Nitsche A, Reinhard T. Clinicopathological findings in persistent corneal cowpox
infection. JAMA Ophthalmol 2013 Jun 13:1-2
Eberwein P, Haeupler A, Kuepper F, Wagner D, Kern WV, Muntau B, Racz P, Agostini H, Poppert S. Human infection with marten
tapeworm. Emerg Infect Dis 2013; 19: 1152-4.
Werner G, Coque TM, Franz CM, Grohmann E, Hegstad K, Jensen L, van Schaik W, Weaver K. Antibiotic resistant enterococci – Tales of a
drug resistance gene trafficker. Int J Med Microbiol 2013 303(6-7):360-79.
Meier B, Schmidt A, Kalmar G, Caca K, Wagner D. Manifestation eines abdominellen inflammatorischen Immunrekonstitutions-Syndroms
assoziiert mit einer nicht tuberkulösen Mykobakterien-Infektion - Ein Fallbericht. Z Gastroenterol. 2013;51(5):440-3.
Kern WV. [Antibiotics in patients with fever and neutropenia.] Dtsch Med Wochenschr 2013; 138: 1217-20.
Hagel S, Pletz MW, Brunkhorst FM, Seifert H, Kern WV. Bakteriämie und Sepsis. Internist 2013; 54(4):399-407.]
Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM,
Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ,
Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Surviving sepsis campaign:
international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med 41 (2013) 580-637.
Engelhardt M, Eber SW, Germing U, Heimpel H, Kern WV, Schmugge M. Prävention von Infektionen und Thrombosen nach Splenektomie
oder funktioneller Asplenie. DGHO, Berlin, 2013, https://www.onkopedia.com/de/onkopedia/guidelines/praevention-von-infektionen-und-
thrombosen-nach-splenektomie-oder-funktioneller-asplenie
Lasek R, Adam D, Barker M, Bauer T, Dalhoff K, Doerr W, Höffken K, Höffler D, Kern WV, Luckhaupt H, Mörike K, Schäfer H, Suttorp
N, Ukena D. Therapieempfehlungen der Arzneimittelkommission der deutschen Ärzteschaft: Atemwegsinfektionen, 3. Auflage. AVP
Arzneiverordnung in der Praxis 40. AkdÄ, Berlin, 2013.
Kern WV. Versorgung und Behandlung von EHEC/HUS-Patienten - Erfahrungen und Perspektiven aus infektiologischer Sicht.
Bundesgesundheitsbl 56 (2013) 87-94.
Thoden J, Potthoff A, Bogner JR, Brockmeyer NH, Esser S, Grabmeier-Pfistershammer K, Haas B, Hahn K, Härter G, Hartmann M,
Herzmann C, Hutterer J, Jordan AR, Lange C, Mauss S, Meyer-Olson D, Mosthaf F, Oette M, Reuter S, Rieger A, Rosenkranz T, Ruhnke M,
Schaaf B, Schwarze S, Stellbrink HJ, Stocker H, Stoehr A, Stoll M, Träder C, Vogel M, Wagner D, Wyen C, Hoffmann C; Deutsche AIDS
Gesellschaft; Österreichische AIDS-Gesellschaft. Therapy and prophylaxis of opportunistic infections in HIV-infected patients: a guideline
by the German and Austrian AIDS societies (DAIG/ÖAG) (AWMF 055/066). Infection 41 (2013) Suppl 2:S91-115.
Herrmann M, Abdullah S, Alabi A, Alonso P, Friedrich AW, Fuhr G, Germann A, Kern WV, Kremsner PG, Mandomando I, Mellmann AC,
Pluschke G, Rieg S, Ruffing U, Schaumburg F, Tanner M, Peters G, von Briesen H, von Eiff C, von Müller L,Grobusch MP. Staphylococcal
disease in Africa – another neglected ‘tropical’ disease. Future Microbiol 8 (2013) 17-26.
Dalhoff K, Ewig S, Abele-Horn M, Andreas S, Bauer TT, von Baum H, Deja M, Gastmeier P, Gatermann S, Gerlach H, Grabein B, Höffken
G, Kern W, Kramme E, Lange C, Lorenz J, Mayer K, Nachtigall I, Pletz M, Rohde G, Rosseau S, Schaaf B, Schaumann R, Schreiter D,
Schütte H, Seifert H, Sitter H, Spies C, Welte T. Adult patients with nosocomial pneumonia: epidemiology, diagnosis, and treatment. Dtsch
Arztebl Int 110 (2013) 634-40.
2012
Plicht B, Kaasch AJ, Kern WV. Infektiöse Endokarditits: Was gibt’s Neues? Hausarzt 49 (2012) 38-44.
Diener A, Altiner A, Berner B, Feldmeier G, Köchling A, Löffler C, Schröder H, Siegel A, Wollny A, Kern WV. Converting habits of
antibiotic prescribing for respiratory tract infections in German primary care - the cluster-randomized controlled CHANGE-2 trial. BMC
Family Practice 13 (2012) 124.
van Ingen J, Griffith DW, Aksamit TR, Wagner D. Pulmonary diseases by non-tuberculous mycobacteria. In: Tuberculosis (Eds.: Lange C,
Migliori GB). Eur Respir Monograph 58, Chapter 3 (2012): 25-37.
Giehl C, Lange C, Duarte R, Bothamley G, Gerlach C, Cirillo DM, Wagner D, Kampmann B, Goletti D, Jürs T, and Sester M. TBNET -
Collaborative research on tuberculosis in Europe. Eur J Microbiol Immunol 2 (4): 264-274.
Meier B, Kalmar G, Caca K, Wagner D. Manifestation of an abdominal immune reconstitution inflammatory syndrome associated with a
nontuberculous mycobacterial infection - A case report. Z Gastroenterol (accepted)
Krudewig J, Baumann U, Bernuth von H, Borte M, Burkhard-Meier U, Dueckers G, Foerster-Waldl E, Franke K, Habermehl P, Hönig M,
Kern WV, Kösters K, Kugel K, Lehrnbecher T, Liese J, Marks R, Müller GA, Müller R, Nadal D, Peter HH, Pfeiffer-Kascha D, Schneider
M, Sitter H, Späth P, Wahn V, Welte T, Niehues T. [Interdisciplinary AWMF Guideline for the Treatment of Primary Antibody
Deficiencies]. Klin Pädiatr 224 (2012) 404-15.
Dalhoff K, Abele-Horn M, Andreas S, Bauer T, von Baum H, Deja M, Ewig S, Gastmeier P, Gatermann S, Gerlach H, Grabein B, Höffken
G, Kern W.V., Kramme E, Lange C, Lorenz J, Mayer K, Nachtigall I, Pletz M, Rohde G, Rosseau S, Schaaf B, Schaumann R, Schreiter D,
Schütte H, Seifert H, Sitter H, Spies C, Welte T. S3-Leitlinie Epidemiologie, Diagnostik und Therapie erwachsener Patienten mit
nosokomialer Pneumonie. Pneumologie 66 (2012) 707-65.
Borde JP, Kern WV. MRSA-Therapie. Dtsch Med Wochenschr 137 (2012) 2553-7.
Kern WV, de With K. Rationale Antibiotikaverordnung - Mehr Herausforderungen als Erfolge. Bundesgesundheitsbl 55 (2012) 1418-26.
Augustin J, Mangiapane S, Kern WV. Antibiotika-Verordnungen im Jahr 2010 im regionalen Vergleich. Zentralinstitut für die
kassenärztliche Versorgung in Deutschland, Berlin, 2012. http://www.versorgungsatlas.de/fileadmin/ziva_docs/Antibiotika_Bericht_final.pdf
Kaase M, Kern WV. [What does ESBL mean?]. Dtsch Med Wochenschr 137 (2012) 2010-3.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2012 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Verlag, Berlin Heidelberg New York 2012, pp. 311-38.
Esser S, Rieg S. [Syphilis und gonorrhoea: Sexually transmitted infections of the past?]. Dtsch Med Wochenschr 137 (2012) 1560-4.
Borde JP, Trummer C, Kern WV. [25-year-old traveller returning home with a furuncular lesion]. Dtsch Med Wochenschr 137 (2012) 1589-
90.
Borde JP, Kern WV, Becker J, Bertz H, Hübner J, Offensperger WB. [Hepatitis B reactivation following immunosuppressive therapy and
screening adherence: a neglected problem?]. Dtsch Med Wochenschr 137 (2012) 1458-62.
Bumbacea D, Arend SM, Eyuboglu F, Fishman JA, Goletti D, Ison MG, Jones CE, Kampmann B, Kotton CN, Lange C, Ljungman P,
Milburn H, Morris MI, Muller E, Muñoz P, Nellore A, Rieder HL, Sester U, Theodoropoulos N, Wagner D, Sester M. The risk of
tuberculosis in transplant candidates and recipients: A TBNET consensus statement. Eur Respir J 2012; 40:990-1013
Hagel S, Kern WV, Pletz MW. Haut- und Weichteilinfektionen, Osteomyelitis, „diabetischer Fuß“. In: Busse O, Fleig WE, Mayet WJ,
Mertens PR, Meyer J, Müller OA, Pfeifer M, Pletz MN, Weiss N (Hrsg.) Rationelle Diagnostik und Therapie in der Inneren Medizin,
Kapitel: Infektionskrankheiten. 33. Lieferung. Urban und Schwarzenberg, München Wien Baltimore 2012.
Kern WV, Kresken M, Wallmann J, Kaspar H. Kennen Sie GERMAP ? Krankenhaushygiene up2date 7 (2012) 15565.
de With K, Stocker H, Borde J, Kern WV. [Antibiotics: new and old drugs, rational prescription]. Dtsch Med Wochenschr 137 (2012) 186-9.
Kern WV, de With K. Fortbildungsinitiative Antibiotic Stewardship für Krankenhausärzte und Apotheker. Krankenhaushygiene up2date 7
(2012) 47-54.
2011
van Ingen J, Wagner D. Epidemiology of nontuberculous mycobacterial disease in Germany and worldwide. Pneumologe 8 (2011) 396-403.
Sieg SR, Kern WV. Die nosokomiale Staphylococcus aureus-Bakteriämie. Krankenhaushygiene up2date 6 (2011) 261-72.
Kern WV. Na? Sind Sie geimpft? (Editorial) Krankenhaushygiene up2date 6 (2011) 253.
Plicht B, Kaasch A, Kern WV. [Infective endocarditis]. Dtsch Med Wochenschr 136 (2011) 2470-3.
Pletz MW, Zanger P, Jilg W, Kern WV. [Vaccinations]. Dtsch Med Wochenschr 136 (2011) 2011-5.
Kern WV, Nink K. Antibiotikaverbrauch im ambulanten Bereich. In: BVL, PEG, if (Hrsg.) GERMAP2010 Antibiotika-Resistenz und -
Verbrauch. Antiinfectives Intelligence, Rheinbach 2011, pp. 11-6.
de With K, Kern WV, Meyer E. Antibiotikaverbrauch im Krankenhaus. In: BVL, PEG, if (Hrsg.) GERMAP2010 Antibiotika-Resistenz und -
Verbrauch. Antiinfectives Intelligence, Rheinbach 2011, pp. 17-21.
Kern WV, Fellhauer M. Antimykotikaverbrauch. In: BVL, PEG, if (Hrsg.) GERMAP2010 Antibiotika-Resistenz und -Verbrauch.
Antiinfectives Intelligence, Rheinbach 2011, pp. 22-4.
de With K, Schneidereit M. Antibiotikaverbrauchsdaten – Methodik und Quellen. In: BVL, PEG, if (Hrsg.) GERMAP2010 Antibiotika-
Resistenz und -Verbrauch. Antiinfectioves Intelligence, Rheinbach 2011, pp. 137-40.
Leemhuis J, Kern WV, de With K. Therapie mit Antiinfektiva. In: Tonner PH, Hein L (Hrsg.) Pharmakologie in Anästhesie und
Intensivmedizin – Grundlagen und Klinische Konzepte. Springer Verlag, Berlin Heidelberg New York 2011, pp. 371-90.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2011 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Verlag, Berlin Heidelberg New York 2011, pp. 311-38.
Read RC, Cornaglia G, Kahlmeter G; European Society of Clinical Microbiology and Infectious Diseases Professional Affairs Workshop
group. Professional challenges and opportunities in clinical microbiology and infectious diseases in Europe. Lancet Infect Dis 11 (2011) 408-
15.
Borde JP, Offensberger WB, de With K. [Diagnosis and treatment of Pneumocystis jirovecii pneumonia.] Dtsch Med Wochenschr 136
(2011) 1426-30.
Diel R, Goletti D, Ferrara G, Bothamley G, Cirillo D, Kampmann B, Lange C, Losi M, Markova R, Migliori GB, Nienhaus A, Ruhwald M,
Wagner D, Zellweger JP, Huitric E, Sandgren A, Manissero D. Interferon-γ release assays for the diagnosis of latent M. tuberculosis
infection: a systematic review and meta-analysis. Eur Resp J 37 (2011) 88-99 .
Dobler G, Rieg S. [Tick-borne infections.] Dtsch Med Wochenschr 136 (2011) 1175-9.
Theilacker C, Brunkhorst F, Kern WV. OPSI-Syndrom – Sepsis bei anatomischer oder funktioneller Apslenie. Intensiv-News 2011: 14-6.
Kaasch AJ, Rieg S, Neumann S, Seifert H, Kern WV. Measuring mortality in Staphylococcus aureus bloodstream infections: are 3 months of
follow-up enough? Infection 39 (2011) 281-2.
Wagner D, Lange B, Hoffmann H, Kern WV. Tuberkulose und nicht-tuberkulöse Mykobakteriosen. In: Deutsche Gesellschaft für Innere
Medizin (Hrsg.) Rationelle Diagnostik und Therapie in der Inneren Medizin, Kapitel: Infektionskrankheiten. 31. Lieferung. Urban und
Schwarzenberg, München Wien Baltimore 2011.
Wagner D, Kern WV. [Tuberculosis and nontuberculous mycobacterial infections.] Dtsch Med Wochenschr 136 (2011) 691-4.
Kern WV. [Bacteraemia and sepsis]. Dtsch Med Wochenschr 136 (2011) 182-5.
Dettenkofer M, Ammon A, Astagneau P, Dancer SJ, Gastmeier P, Harbarth S, Humphreys H, Kern WV, Lyytikäinen O, Sax H, Voss A,
Widmer AF. Infection control - a European research perspective for the next decade. J Hosp Infect 77 (2011) 7-10.
2010
Geyer M, Wilpert J, Wiech T, Theilacker C, Stubanus M, Kramer-Zucker A, Fischer KG, Drognitz O, Frydrychowicz A, Kern WV, Walz G,
Pisarski P. Rapidly progressive hepatic alveolar echinococcosis in an ABO-incompatible renal transplant recipient. Transpl Infect Dis 13
(2010) 278-84.
Wüppenhorst N, Lee MK, Rappold E, Kayser G, Beckervordersandforth J, de With K, Serr A. Rhino-orbitocerebral zygomycosis caused by
Conidiobolus incongruus in an immunocompromised patient in Germany. J Clin Microbiol 48 (2010) 4322-5.
Dietrich ES, Strehl E, de With K, Kämmerer W, Wilke M. Pharmakoökonomie. In: Bodmann KF, Grabein B, Expertenkommision der PEG
für Chemotherapie e.V. . Empfehlungen zur kalkulierten parenteralen Initialtherapie bakterieller Erkrankungen bei Erwachsenen, 15. Kapitel.
Chemother J 19 (2010) 248-51.
Kern WV. Antibiotikaverordnung – wer, wo, was, wie? [Editorial] Dtsch Med Wochenschr 135 (2010) 1791.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2010 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Verlag, Berlin Heidelberg New York 2010, pp. 283-308.
de With K. Therapie von Intensivpatienten, kritisch Kranken und multimorbiden Patienten. In: Högger P, Strehl E (Hrsg.) Repititorium
Klinische Pharmazie - Arbeitsbuch für Prüfung und Praxis, 2. überarbeitete Aufl. GOVI Verlag Pharmazeutischer Verlag 2010
Sotgiu G, Centis R, D'ambrosio L, De Lorenzo S, D'arcy Richardson M, Lange C, Manissero D, Migliori GB; TBNET MDR-TB project.
Development of a standardised tool to survey MDR-/XDR-TB case management in Europe. Eur Respir J 36 (2010) 208-11.
Kern WV. Was gibt es Neues in den neuen Leitlinien zur Clostridium difficile-Infektion? Krankenhaushygiene up2date 5 (2010) 213-20.
Kern WV. Management of Staphylococcus aureus bacteremia and endocarditis: progresses and challenges. Curr Opin Infect Dis 23 (2010)
346-58.
Kern WV. Warum nur MRSA? (Editorial) Krankenhaushygiene up2date 5 (2010) 1-2.
Brunkhorst FM, Gastmeier P, Kern WV, Krüger W, Mayer K, Weimann A, Welte T, Putensen C, Werdan K, Reinhart K. Prävention und
Nachsorge der Sepsis – 1. Revision der S-2k Leitlinien der Deutschen Sepsis-Gesellschaft e.V. (DSG) und der Deutschen Interdisziplinären
Vereinigung für Intensiv- und Notfallmedizin (DIVI). Internist 51 (2010) 925-32.
Reinhart K, Brunkhorst FM, Bone HG, Bardutzky J, Dempfle CE, Forst H, Gastmeier P, Gerlach H, Gründling M, John S, Kern WV,
Kreymann G, Krüger W, Kujath P, Marggraf G, Martin J, Mayer K, Meier-Hellmann A, Oppert M, Putensen C, Quintel M, Ragaller M,
Rossaint R, Seifert H, Spies C, Stüber F, Weiler N, Weimann A, Werdan K, Welte T. Prävention, Diagnose, Therapie und Nachsorge der
Sepsis – 1. Revision der S-2k Leitlinien der Deutschen Sepsis-Gesellschaft e.V. (DSG) und der Deutschen Interdisziplinären Vereinigung für
Intensiv- und Notfallmedizin (DIVI). GMS Ger Med Sci 8 (2010) doc14, auch publiziert in: Reinhart K, Brunkhorst FM (Hrsg.) Thieme
Verlag, Stuttgart New York 2010, pp. 1-84.
Sava IG, Heikens E, Huebner J. Pathogenesis and immunity in enterococcal infections. Clin Microbiol Infect 16 (2010) 533-40.
Kern WV. Risiko und Spektrum opportunistischer Infektionen und deren Prävention unter Immuntherapie. In: Lorenz HM, Manger B, Peter
HH, Sticherling M, Schwarting A (Hrsg.) Immuntherapie interdisziplinär. Ligaturverlag, Stuttgart 2010, pp. 41-8.
Paesmans M, Kern WV. Tüm Nötropenik Hastalar Ayni mi?. In: Akova M, Akan H (Eds.) Febril Nötropeni. Bilimsel Tip Yayinevi, Ankara
2010, pp. 63-74.
Barger A, Handrick W, Kern WV, Lode H. Umfrage: Antibiotikaverbrauch in Deutschland und im europäischen Vergleich. internist praxis
50 (2010) 463-9.
Grünewald T, Kist M, Mutters R, Ruf BR, Kern WV. Clostridium difficile-Infektion. Dtsch Med Wochenschr 135 (2010) 699-703.
Gastmeier P, Brunkhorst FM, Schrappe M, Kern WV, Geffers C. Wie viele nosokomiale Infektionen sind vermeidbar?. Dtsch Med
Wochenschr 135 (2010) 91-3.
Grundmann S, Huebner J, Stuplich J, Koch A, Wu K, Geibel-Zehender A, Bode C, Brunner M. Prosthetic valve endocarditis due to
Actinomyces neuii successfully treated by antibiotic therapy: A first case report and review of the literature. J Clin Microbiol 48 (2010)
1008-11.
ESAC – European Surveillance of Antibiotic Consumption Yearbook 2009. ESAC/EDCD, Antwerpen, 2010. Available from:
http://www.esac.ua.ac.be/main.aspx?c=*ESAC2&n=50036
2009
Kern WV, Frank U. Serious hospital infections – the burden and impact of resistance. Eur Infect Dis 3 (2009) 65-9.
Kern WV, Marchetti O, Drgona L, Akan H, Aoun M, Akova M, de Bock R, Paesmans M, Martens J, Viscoli C, Calandra T. Orales
Moxifloxacin versus Ciprofloxacin plus Amoxicillin-Clavulansäure bei Patienten mit febriler Neutropenie und niedrigem Risiko – eine
prospektive, doppelblinde, randomisierte, multizentrische EORTC Infectious Diseases Group (IDG)-Studie (Studienprotokoll 46001, IDG-
Studie XV. Infection 27 (2009) (Suppl IV) 56-7.
Gastmeier P, Fellhauer M, Heesemann J, Kern WV. Die Antibiotika-Resistenzstrategie – Verbesserung der Aus-, Weiter- und Fortbildung in
Krankenhäusern. Klinikarzt 38 (2009) 562-5.
Höffken G, Lorenz J, Kern WV, Welte T, Bauer T, Dalhoff K, Dietrich E, Ewig S, Gastmeier P, Grabein B, Halle E, Kolditz M, Marre R,
Sitter H für die PEG, DGP, DGI, CAPNETZ-Stiftung. S3-Leitlinie zu Epidemiologie, Diagnostik, antimikrobieller Therapie und
Management von erwachsenen Patienten mit ambulant erworrbenen tiefen Atemwegsinfektionen, 2. Auflage - Kurzfassung. Thieme Verlag,
Stuttgart New York 2009.
Höffken G, Lorenz J, Kern WV, Welte T, Bauer T, Dalhoff K, Dietrich E, Ewig S, Gastmeier P, Grabein B, Halle E, Kolditz M, Marre R,
Sitter H. Epidemiologie, Diagnostik, antimikrobielle Therapie und Management von erwachsenen Patienten mit ambulant erworrbenen tiefen
Atemwegsinfektionen (akute Bronchitis, akute Exazerbation einer chronischen Bronchitis, Influenza und andere respiratorische
Virusinfektionen) sowie ambulant erworbene Pneumonie. S3-Leitlinie der PEG, DGP, DGI und CAPNETZ. Chemotherapie Journal 14
(2005) 97-145.
Höffken G, Lorenz J, Kern WV, Welte T, Bauer T, Dalhoff K, Dietrich E, Ewig S, Gastmeier P, Grabein B, Halle E, Kolditz M, Marre R,
Sitter H. Epidemiologie, Diagnostik, antimikrobielle Therapie und Management von erwachsenen Patienten mit ambulant erworrbenen tiefen
Atemwegsinfektionen (akute Bronchitis, akute Exazerbation einer chronischen Bronchitis, Influenza und andere respiratorische
Virusinfektionen) sowie ambulant erworbene Pneumonie. S3-Leitlinie der PEG, DGP, DGI und CAPNETZ. Update2009. Pneumologie 63
(2009) e1-68.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2009 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Medizin Verlag, Heidelberg 2009, pp. 283-308.
Kern WV, Dettenkofer M. Nosokomiale Infektionen – Herausforderung MRSA und CDAD. Internist (Berl) 50 (2009) 691-703.
de With K. „Hospital Antibiotic Stewardship“ und Deutsche Antibiotika-Resistenzstrategie. Krankenhauspharmazie 5 (2009) 212-4.
Engelhardt M, Haas PS, Theilacker C, Eber SW, Schmugge M, Kern WV, Heimpel H. [Prevention of infections and thromboses after
splenectomy or because of functional loss of the spleen]. Dtsch Med Wochenschr 134 (2009) 897-902.
Rieg S, Lübbert M, Kern WV, Timme S, Gärtner F, Rump JA. Myelodysplastic syndrome with complex karyotype associated with long-term
highly active antiretroviral therapy. Brit J Haematol 2009 (145): 670-3.
Meyer E, Serr A, Schneider C, Utzolino S, Kern WV, Scholz R, Dettenkofer M. Should we screen patients for extended-spectrum beta-
lactamase-producing enterobacteriaceae in intensive care units? Infect Control Hosp Epidemiol 30 (2009) 103-5.
ESAC – European Surveillance of Antibiotic Consumption Yearbook 2008. ESAC, Antwerpen, 2009. Available from:
http://www.esac.ua.ac.be/main.aspx?c=*ESAC2&n=50036
2008
Kern WV. Antibiotika-Prophylaxe und -Therapie bei Patienten mit Neutropenie. Onkologie heute 6 (2008) 25-30.
Kern WV, Schröder H, de With K, Dietrich ES, Nink K. Antibiotikaverbrauch im ambulanten Bereich. In: BVL, PEG, if (Hrsg.)
GERMAP2008 Antibiotika-Resistenz und -Verbrauch. Antiinfectives Intelligence, Rheinbach 2008, pp. 11-6.
de With K, Kern WV, Meyer E, Mielke M. Antibiotikaverbrauch im Krankenhaus. In: BVL, PEG, if (Hrsg.) GERMAP2008 Antibiotika-
Resistenz und -Verbrauch. Antiinfectives Intelligence, Rheinbach 2008, pp. 17-22.
Kern WV, Schneidereit M, Kresken M, de With K. Antibiotikaverbrauchsdaten – Methodik und Quellen. In: BVL, PEG, if (Hrsg.)
GERMAP2008 Antibiotika-Resistenz und -Verbrauch. Antiinfectioves Intelligence, Rheinbach 2008, pp. 132-5.
Kern WV. Bakterielle Infektionen. In: Nowrousian MR (Hrsg.) Supportive Therapie in der Onkologie. Zuckschwerdt Verlag,
Germering/München 2008, pp. 191-208.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2008 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Verlag, Berlin Heidelberg New York 2008, pp. 279-304.
Theilacker C, Rieg S, Hübner J, Kern WV. Rezidivierende Staphylococcus aureus-Infektionen. Kinder- und Jugendmedizin 8 (2008) 101-4.
Werner G, Klare I, Hübner J, Kern WV, Witte W. Vancomycin-resistente Enterokokken. Chemother J 17 (2008) 183-93.
Timmer A, Günther J, Rücker G, Motschall E, Antes G, Kern WV. Pelargonium sidoides extract for acute respiratory tract infections
(Review). The Cochrane Library 2008, Issue 3
ESAC – European Surveillance of Antimicrobial Consumption. ESAC Yearbook 2006. University of Antwerp, Antwerp, 2008.
Dettenkofer M, Widmer AF, Kern WV. [MRSA and other multi-resistant pathogens: an ever increasing problem even in ambulant medicine].
Dtsch Med Wochenschr 133 (2008) 370-371.
Wagner D, Hörster R, Lange B, Lange C. [Evaluation of T-cell interferon-gamma-release assays for the diagnosis of latent and active
tuberculosis]. Dtsch Med Wochenschr 133 (2008) 354-7.
Lange C, Grobusch MP, Wagner D. [Extensively drug-resistant tuberculosis]. Dtsch Med Wochenschr 133 (2008) 374-6.
Kern WV, Weiss G. Was gibt es Neues in der Infektiologie? Dtsch Med Wochenschr 133 (2008) 339.
Rieg S, Theilacker C. Bilderquiz: Afrikanisches Zeckenbissfieber. Dtsch Med Wochenschr 133 (2008) 363-4.
Huebner J, Franz C, Kopp M. [Probiotics--evidence-based medicine or simply hocus-pocus?]. Dtsch Med Wochenschr 133 (2008) 367-9.
2007
Huebner J, Arciola CR. Cave enterococcum! Int J Artif Organs 30 (2007) 852-3.
de With K, Kern WV. Antibiotikaverbrauch in Klinik und Praxis. Krankenhaushygiene up2date 2 (2007) 341-58.
Kern WV. Wenn Fieber kein banaler Infekt ist – Fahndung nach Ursachen der Temperatursollwertverstellung. Notfall- und Hausarztmedizin
33 (2007) 414-21.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2007 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Verlag, Berlin Heidelberg New York 2007, pp. 287-311.
Stubanus M, Gobel H, Rieg S, Walz G, Gerke P. Quiz page. Minimal change glomerulonephritis associated with secondary syphilis. Am J
Kidney Dis 49 (2007) A49-50.
Kern WV. New plasmid-borne quinolone-resistance determinant in Escherichia coli. Future Microbiol 2 (2007) 473-5.
de With K, Fellhauer M. Erhebung und Interpretation von Antiinfektiva-Verbrauchsdaten im Krankenhaus. Antibiotika-Surveillance als
Aufgabe für den Krankenhausapotheker. Krankenhauspharmazie 9 (2007) 362-5.
Timmer A, Antes G, Günther J, Kern WV, Motschall E. Pleargonium sidoides extract (Umckaloabo) for acute respiratory tract infections
(protocol). Cochrane Database of Systematic Reviews 2007, Issue1. Art.No. CD006323.
Seifert H, Abele-Horn M, Fätkenheuer G, Glück T, Jansen B, Kern WV, Mack D, Plum G, Reinert RR, Roos R, Salzberger B, Shah PM,
Ullmann U, Weiß M, Welte T, Wisplinghoff H. Blutkulturdiagnostik - Sepsis, Endokarditis, Katheterinfektionen, Teil II. In: Mauch H,
Podbielski A, Herrmann M, Kniehl E (Hrsg.) Mikrobiologisch-infektiologische Qualitätsstandards (MiQ) 3b. 2. Auflage. Verlag Urban &
Fischer, München 2007.
de With K. Therapie von Intensivpatienten, kritisch Kranken und multimorbiden Patienten. In: Högger P, Strehl E (Hrsg.) Repititorium
Klinische Pharmazie, Arbeitsbuch für Prüfung und Praxis 2007, Kapitel Besondere Therapieregime. GOVI Verlag Pharmazeutischer Verlag.
522 S. Zahlreiche Abbildungen und Tabellen, gebunden. ISBN 978-3-7741-1060-1
Mahamoud A, Chevalier J, Alibert-Franco S, Kern WV, Pagès JM. Antibiotic efflux pumps in Gram-negative bacteria, the inhibitor response
strategy. J Antimicrob Chemother 59 (2007) 1223-9.
2006
Schwacha H, Kern WV, Wagner D. Duodenal perforation of a Dacron endoprosthesis. Endoscopy 38 (2006) 51. [Pubmed]
Leibovici L, Paul M, Cullen M, Bucaneve G, Gafter-Gvili A, Fraser A, Kern WV. Antibiotic prophylaxis in neutropenic patients: new
evidence, practical decisions. Cancer 107 (2006) 1743-51.
Kern WV, Steib-Bauert M, de With K. Comment on: Hospital consumption of antibiotics in 15 European countries: results of the ESAC
retrospective data collection (1997-2002). J Antimicrob Chemother 58 (2006) 900-1.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2006 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Verlag, Berlin Heidelberg New York 2006, pp. 326-50.
Cometta A, Marchetti O, Calandra T, Bille J, Kern WV, Zinner S; Infectious Diseases Group of the European Organization for Research and
Treatment of Cancer (EORTC-IDG).In vitro antimicrobial activity of moxifloxacin against bacterial strains isolated from blood of
neutropenic cancer patients. Eur J Clin Microbiol Infect Dis 25 (2006) 537-40.
Kern WV. Kommentar: Auch andere Fluorchinolone fielen durch Unverträglichkeitsreaktionen auf. Dtsch Med Wschr 131 (2006) 1306.
Jaeger M, Maier D, Kern WV, Südkamp NP. Antibiotics in trauma and orthopedic surgery – a primer of evidence-based recommendations.
Injury 37 Suppl 2 (2006) S74-80.
Wagner D, Vos MC, Buiting AGM+, Serr A, Bergmans AMC, Kern WV, Schouls LM. Infections due to ‘Mycobacterium tilburgii’. Emerg
Inf Dis (2006). Available from http://www.cdc.gov/ncidod/EID/vol12no03/05-1139.htm
Kern WV. Kommentar: MRSA ist im ambulanten Bereich bemerkenswert virulent. Dtsch Med Wschr 131 (2006) 853.
Kern WV. Low risk febrile neutropenia: risk assessment and management. Clin Infect Dis 42 (2006) 533-40.
Kern WV. Daptomycin: first in a new class of antibiotics for complicated skin and soft tissue infections. Int J Clin Pract 60 (2006) 370-8.
Lorenz J, Kern WV, Halle E, Grabein B. Antibiotika in der Pneumologie. Pneumologe 3 (2006) 59-76.
Sandherr M, Einsele H, Hebart H, Kahl C, Kern WV, Kiehl M, Massenkeil G, Penack O, Schiel X, Schuettrumpf S, Ullmann AJ, Cornely
OA. Antiviral prophylaxis in patients with haematological malignancies and solid tumours: guidelines of the Infectious Diseases Working
Party (AGIHO) of the German Society for Hematology and Oncology (DGHO). Ann Oncol 17 (2006) published online January 12.
2005
Kern WV. Outpatient management in patients with neutropenia after intensive chemotherapy – is it safe? Ann Oncol 16 (2005) 179-80.
Nilsson-Ehle I, McKendrick M, Kern WV, Horgan M, Black FT. UEMS and the specialty of infectious diseases. ESCMID News 2005: 13-
14.
Kern WV, Wagner D, Hirsch HH. Infektionen nach Organtransplantation. Internist 46 (2005) 630-42.
Kern WV. Bakterielle Infektionskrankheiten. In: Paumgartner G, Steinbeck G (Hrsg.) Therapie innerer Krankheiten. 11. Auflage. Springer
Verlag, Berlin Heidelberg New York 2005, pp. 1531-69.
Kern WV, Ruf BR. Infektiologie – Neue Szenarien, zunehmende Aufgaben. Dtsch Med Wschr 130 (2005) 1559-62.
Höffken G, Lorenz J, Kern WV, Welte T, Bauer T, Dalhoff K, Dietrich E, Ewig S, Gastmeier P, Grabein B, Halle E, Kolditz M, Marre R,
Sitter H. S3-Leitlinie zu Epidemiologie, Diagnostik, antimikrobieller Therapie und Management von erwachsenen Patienten mit ambulant
erworrbenen tiefen Atemwegsinfektionen - Kurzfassung. Thieme Verlag, Stuttgart New York 2005.
Höffken G, Lorenz J, Kern WV, Welte T, Bauer T, Dalhoff K, Dietrich E, Ewig S, Gastmeier P, Grabein B, Halle E, Kolditz M, Marre R,
Sitter H. Epidemiologie, Diagnostik, antimikrobielle Therapie und Management von erwachsenen Patienten mit ambulant erworrbenen tiefen
Atemwegsinfektionen (akute Bronchitis, akute Exazerbation einer chronischen Bronchitis, Influenza und andere respiratorische
Virusinfektionen) sowie ambulant erworbene Pneumonie. S3-Leitlinie der PEG, DGP, DGI und CAPNETZ. Chemotherapie Journal 14
(2005) 97-145.
Höffken G, Lorenz J, Kern W, Welte T, Bauer T, Dalhoff K, Dietrich E, Ewig S, Gastmeier P, Grabein B, Halle E, Kolditz M, Marre R,
Sitter H. S3-Leitlinie Ambulant erworbene Pneumonie und tiefe Atemwegsinfektionen. Pneumologie 59 (2005) 612-64.
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2005 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Verlag, Berlin Heidelberg New York 2005, pp. 325-49.
Schröder H, Nink K, Günther J, Kern WV. Antibiotika: Solange sie noch wirken ..... Revisited: 2001 – 2004. WIdo/Siftung Warentest/
Universitätsklinikum Freiburg, Bonn Freiburg, 2005.
Huebner J, Dettenkofer M, Kern WV. Vancomycin-resistente Enterokokken. Dtsch Med Wschr 130 (2005) 2463-8.
Fabretti F, Huebner J. Implant infections due to enterococci: role of capsular polysaccharides and biofilm. Int J Artif Org 28 (2005) 1079-90.
2004
Kern WV. Unnötige Antibiotikagabe ist häufig und kann minimiert werden. Dtsch Med Wschr 129 (2004) 1052 (auch erschienen in DMW
Praxis plus 5:174).
Kern WV. Antibiotika und Chemotherapeutika. In: Schwabe U, Paffrath D (Hrsg.) Arzneiverordnungsreport 2004 - Aktuelle Daten, Kosten,
Trends und Kommentare. Springer Verlag, Berlin Heidelberg New York 2004, pp. 267-80.
Cometta A, Kern WV. Traitement antibiotique oral des neutropénies fébriles en onco-hématologie. L´experience du Groupe Antimicrobien
de L´EORTC. Presse Méd 33 (2004) 327-9.
de With K, Schröder H, Meyer E, Nink K, Hoffmann S, Steib-Bauert M, Kämmerer R, Rueß S, Daschner FD, Kern WV.
Antibiotikaanwendung in Deutschland im europäischen Vergleich. Dtsch Med Wschr 129 (2004) 1987-92.
Wagner D, Young LS. Nontuberculous mycobacterial infections: a clinical review. Infection 32 (2004) 257-70.
Kern WV. Indikation für mikrobiologische Untersuchungen bei massiven Durchfällen. Chir Praxis 63 (2004) 692.
Theilacker C, Krueger WA, Kropec A, Huebner J. Rationale for the development of immunotherapy regimens against enterococcal
infections. Vaccine 22S (2004) S31-8.
2003
Bauer TM, Wagner D, Kern WV. Fieber unklarer Genese. In: Deutsche Gesellschaft für Innere Medizin (Hrsg.) Rationelle Diagnostik und
Therapie in der Inneren Medizin, Kapitel: Infektionskrankheiten. 14. Lieferung. Urban und Schwarzenberg, München Wien Baltimore 2003.
Buchheidt D, Böhme A, Cornely OA, Fätkenheuer G, Fuhr HG, Heussel G, Junghanss C, Karthaus M, Kellner O, Kern WV, Schiel X, Sezer
O, Südhoff T, Szelenyi H. Diagnosis and treatment of documented infections in neutropenic patients. Recommendations of the Infectious
Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Ann Hematol 82 (2003) S127-32.
Cornely OA, Böhme A, Buchheidt D, Glasmacher A, Kahl C, Karthaus M, Kern WV, Krüger W, Maschmeyer G, Ritter J, Salwender HJ,
Sandherr M, Schiel X, Schuttrumpf S, Sieniawski M, Silling G, Ullmann AJ, Wolf HH. Prophylaxis of invasive fungal infections in patients
with hematological malignancies and solid tumors. Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of
Hematology and Oncology (DGHO). Ann Hematol 82 (2003) S186-S200.
Elies W, Grünewald T, Kern WV. Infektionen der oberen Luftwege. In: Deutsche Gesellschaft für Innere Medizin (Hrsg.) Rationelle
Diagnostik und Therapie in der Inneren Medizin, Kapitel: Infektionskrankheiten. 14. Lieferung. Urban und Schwarzenberg, München Wien
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