Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De...

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Pre-Hospital Care Management of a Potential Spinal Cord Injured Patient: A Systematic Review of the Literature and Evidence-Based Guidelines Henry Ahn, 1 Jeffrey Singh, 2 Avery Nathens, 3 Russell D. MacDonald, 4 Andrew Travers, 5 John Tallon, 6 Michael G. Fehlings, 1 and Albert Yee 1 Abstract An interdisciplinary expert panel of medical and surgical specialists involved in the management of patients with potential spinal cord injuries (SCI) was assembled. Four key questions were created that were of significant interest. These were: (1) what is the optimal type and duration of pre-hospital spinal immobilization in patients with acute SCI?; (2) during airway manipulation in the pre-hospital setting, what is the ideal method of spinal immobilization?; (3) what is the impact of pre-hospital transport time to definitive care on the outcomes of patients with acute spinal cord injury?; and (4) what is the role of pre-hospital care providers in cervical spine clearance and immobilization? A systematic review utilizing multiple databases was performed to determine the current evidence about the specific questions, and each article was independently reviewed and assessed by two reviewers based on inclusion and exclusion criteria. Guidelines were then created related to the questions by a national Canadian expert panel using the Delphi method for reviewing the evidence-based guidelines about each question. Recommendations about the key questions included: the pre-hospital immobilization of patients using a cervical collar, head immobilization, and a spinal board; utilization of padded boards or inflatable bean bag boards to reduce pressure; transfer of patients off of spine boards as soon as feasible, including transfer of patients off spinal boards while awaiting transfer from one hospital institution to another hospital center for definitive care; inclusion of manual in-line cervical spine traction for airway management in patients requiring intubation in the pre-hospital setting; transport of patients with acute traumatic SCI to the definitive hospital center for care within 24 h of injury; and training of emergency medical personnel in the pre-hospital setting to apply criteria to clear patients of cervical spinal injuries, and immobilize patients suspected of having cervical spinal injury. Key words: pre-hospital care; spinal cord injury; systematic review Introduction G reat care must be taken when providing medical care to an acutely injured patient prior to arrival at hospital. About 2% of all blunt trauma patients will have sustained a spinal cord injury, and these rates are higher in the setting of severe closed head injury (Crosby, 1992, 2006). Patients with acute spinal cord injury (SCI) are at risk of neurologic dete- rioration due to secondary injury to the spinal cord (Fehlings and Louw, 1996). A potential cause of secondary injury is through inadvertent manipulation of the spinal cord in the setting of an unstable spinal column injury (Crosby, 1992; Eismont et al., 2004; Fehlings and Louw, 1996; Fenstermaker, 1993). Minimizing the chances of secondary injury can be challenging in the pre-hospital setting due to the local and transport environment, a lack of resources, and heterogeneity in health care providers and their skill sets (Hauswald et al., 2000). Furthermore, treatments initiated prior to arrival in the hospital can lead to significant morbidity in other body re- gions, such as sacral and occipital ulcers (Cordell et al., 1995; 1 Department of Surgery, 2 Department of Interdepartmental Medicine, Division of Critical Care, 3 Department of Surgery, Health Policy, Management and Evaluation, and 4 Department of Research and Development, Ornge Transport Medicine and Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada. 5 Department of Emergency Medicine, and 6 Department of Emergency Medicine, Surgery and Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada. JOURNAL OF NEUROTRAUMA 28:1341–1361 (August 2011) ª Mary Ann Liebert, Inc. DOI: 10.1089=neu.2009.1168 1341

Transcript of Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De...

Page 1: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Pre-Hospital Care Management of a PotentialSpinal Cord Injured Patient: A Systematic Reviewof the Literature and Evidence-Based Guidelines

Henry Ahn,1 Jeffrey Singh,2 Avery Nathens,3 Russell D. MacDonald,4 Andrew Travers,5

John Tallon,6 Michael G. Fehlings,1 and Albert Yee1

Abstract

An interdisciplinary expert panel of medical and surgical specialists involved in the management of patientswith potential spinal cord injuries (SCI) was assembled. Four key questions were created that were of significantinterest. These were: (1) what is the optimal type and duration of pre-hospital spinal immobilization in patientswith acute SCI?; (2) during airway manipulation in the pre-hospital setting, what is the ideal method of spinalimmobilization?; (3) what is the impact of pre-hospital transport time to definitive care on the outcomes ofpatients with acute spinal cord injury?; and (4) what is the role of pre-hospital care providers in cervical spineclearance and immobilization? A systematic review utilizing multiple databases was performed to determine thecurrent evidence about the specific questions, and each article was independently reviewed and assessed by tworeviewers based on inclusion and exclusion criteria. Guidelines were then created related to the questions by anational Canadian expert panel using the Delphi method for reviewing the evidence-based guidelines abouteach question. Recommendations about the key questions included: the pre-hospital immobilization of patientsusing a cervical collar, head immobilization, and a spinal board; utilization of padded boards or inflatable beanbag boards to reduce pressure; transfer of patients off of spine boards as soon as feasible, including transfer ofpatients off spinal boards while awaiting transfer from one hospital institution to another hospital center fordefinitive care; inclusion of manual in-line cervical spine traction for airway management in patients requiringintubation in the pre-hospital setting; transport of patients with acute traumatic SCI to the definitive hospitalcenter for care within 24 h of injury; and training of emergency medical personnel in the pre-hospital setting toapply criteria to clear patients of cervical spinal injuries, and immobilize patients suspected of having cervicalspinal injury.

Key words: pre-hospital care; spinal cord injury; systematic review

Introduction

Great care must be taken when providing medical careto an acutely injured patient prior to arrival at hospital.

About 2% of all blunt trauma patients will have sustained aspinal cord injury, and these rates are higher in the setting ofsevere closed head injury (Crosby, 1992, 2006). Patients withacute spinal cord injury (SCI) are at risk of neurologic dete-rioration due to secondary injury to the spinal cord (Fehlingsand Louw, 1996). A potential cause of secondary injury is

through inadvertent manipulation of the spinal cord in thesetting of an unstable spinal column injury (Crosby, 1992;Eismont et al., 2004; Fehlings and Louw, 1996; Fenstermaker,1993). Minimizing the chances of secondary injury can bechallenging in the pre-hospital setting due to the local andtransport environment, a lack of resources, and heterogeneityin health care providers and their skill sets (Hauswald et al.,2000). Furthermore, treatments initiated prior to arrival in thehospital can lead to significant morbidity in other body re-gions, such as sacral and occipital ulcers (Cordell et al., 1995;

1Department of Surgery, 2Department of Interdepartmental Medicine, Division of Critical Care, 3Department of Surgery, Health Policy,Management and Evaluation, and 4Department of Research and Development, Ornge Transport Medicine and Division of EmergencyMedicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

5Department of Emergency Medicine, and 6Department of Emergency Medicine, Surgery and Community Health and Epidemiology,Dalhousie University, Halifax, Nova Scotia, Canada.

JOURNAL OF NEUROTRAUMA 28:1341–1361 (August 2011)ª Mary Ann Liebert, Inc.DOI: 10.1089=neu.2009.1168

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Page 2: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Davies et al., 1996; De Lorenzo et al., 1996; Hamilton andPons, 1996; Hauswald et al., 2000; Johnson et al., 1996; Krellet al., 2006; Luscombe and Williams, 2003; Main and Lovell,1996; Sheerin and de Frein, 2007; Walton et al., 1995). There istremendous variation in how care is administered prior toarrival at the hospital and during transport from one hospitalto another (Armitage et al., 1990; Burney et al., 1989; Fla-bouris, 2001). Some care models and treatments may providepatients with improved safety and reduce morbidity, andthus improve efficiency of care delivery. These variations ofpractice served as the impetus to perform a systematic review,in conjunction with a series of other systematic reviews re-lated to SCI care. The purpose of this study was to provideevidence-based guidelines agreed upon by a multi-disciplin-ary expert panel to identify optimal care in key areas in thepre-hospital setting for patients with potential SCI.

Four questions that were of clinical relevance and thatcould have significant impact on patient care were deter-mined by a multidisciplinary expert panel. These four ques-tions posed for the systematic review were:

1. What is the optimal type and duration of spinal im-mobilization in patients with acute SCI?

2. During airway manipulation in the pre-hospital setting,what is the ideal method of spinal immobilization?

3. What is the impact of pre-hospital transport time todefinitive care on the outcomes of patients with acuteSCI?

4. What is the role of pre-hospital care providers in cer-vical spine clearance and immobilization?

These four questions then served as the basis of oursystematic review of pre-hospital care of potential spinal-cord-injured patients. The systematic review method wasutilized to systematically collate and assess the literature,while minimizing bias in the assembly and interpretation ofthe evidence. Following an exhaustive search of the literatureand collation of the identified studies into evidentiary tables,the evidence was graded and synthesized into guidelines thatwere refined through consensus using Delphi methodology(Hasson et al., 2000; Keeney et al., 2001; Kennedy, 2004).

Methods

Four questions of pertinent interest to a multi-disciplinarycommittee with expertise in the management of SCI wereagreed upon to form the basis of the systematic review. Eachof the four questions was amenable to a systematic review.Members of this committee included a traumatologist (AveryNathens), three trauma triage specialists in emergency med-icine (Russell MacDonald, Andrew Tavers, and John Tallon),three spine surgeons (Henry Ahn, Michael Fehlings, and Al-bert Yee), a critical care intensivist ( Jeffrey Singh), and afundamental scientist in SCI research (Darryl Baptiste).

A primary literature search was performed using theMEDLINE, CINAHL, Embase, and Cochrane databases. Asecondary search strategy incorporated articles referred to inmeta-analyses, systematic and non-systematic review articlesthat were found in the primary search. Additional articles thatwere listed in the references of retrieved original articles couldbe also included in the secondary search strategy. The litera-ture searches addressed publications produced from 1966 toApril 2008. Two reviewers independently selected the articles

based on the inclusion and exclusion criteria, determined theirlevel of evidence, and assessed their methodological qualityaccording to the Downs and Black criteria (Downs and Black,1998). Disagreement between the reviewers was reconciled bya third reviewer. All articles were directly related to pre-hospital care, and limited to human studies by excluding the‘‘animal’’ Medical Subject Heading (MeSH). The MeSH searchterms used were: ‘‘pre-hospital care,’’ ‘‘spinal trauma,’’ and‘‘spinal cord injury.’’

Based on this methodology 66 articles were screened, and47 were eligible based upon criteria utilized for pre-hospitalcare. These were scored according to the Downs and Blackcriteria (Downs and Black, 1998). The main results of eacharticle and the reviewers’ assessments were summarized in anevidentiary table (Table 1).

Evidence-based responses were then composed for the fourquestions. A panel of 5 to 10 multi-disciplinary experts (fromthe Solutions Network [Acute Practice Network]) using theDelphi method scrutinized the evidence-based statements forthe specific questions. A level of consensus of 80% or higherwas considered to be a strong agreement. Based on the level ofagreement and the comments from the expert panel, recom-mendations were formulated for each question related to pre-hospital care.

Findings from the systematic review

Question 1. What is the optimal type and duration ofspinal immobilization in patients with acute SCI?

In all, 25 studies were reviewed for this particular question(Chan et al., 1996; Chandler et al., 1992; Cordell et al., 1995;Cornwell et al., 2001; Davies et al., 1996, De Lorenzo et al.,1996; Gerling et al., 2000; Graziano et al., 1987; Hamilton andPons, 1996; Hauswald et al., 2000, 1998; Huerta et al., 1987;Johnson et al., 1996; Krell et al., 2006; Luscombe and Williams,2003; Main and Lovell, 1996; Mazolewski and Manix, 1994;Nypaver and Treloar, 1994; Peery et al., 2007; Perry et al., 1999;Schafermeyer et al., 1991; Schriger et al., 1991; Sheerin and deFrein, 2007; Walton et al., 1995; Waninger et al., 2001). Mostevidence in the literature was based on biomechanical studieswith volunteers. The studies showed that immobilization witha board and collar and head immobilization between towels orfoam wedges provided the most stable biomechanical immo-bilization (Huerta et al., 1987; Perry et al., 1999). The additionof the board to the cervical collar provided statistically sig-nificantly more immobilization than a collar by itself(Chandler et al., 1992; Graziano et al., 1987). There were notenough studies to recommend exact types of collars. Certainforms of strapping, if applied appropriately in terms of loca-tion and tightness may further reduce lateral thoraco-lumbarspinal movement, but the clinical relevance of this reduction isnot known (Mazolewski and Manix, 1994; Peery et al., 2007).

The use of rigid boards can lead to discomfort at the occiputand sacrum and increased pressures that can lead to tissuenecrosis (Chan et al., 1996; Hauswald et al., 2000; Main andLovell, 1996; Sheerin and de Frein, 2007; Walton et al., 1995).Cushioning the board can lead to increased comfort and de-crease the amount of pressure at the occiput and sacrumwithout compromising biomechanical immobilization (Chanet al., 1996; Hauswald et al., 2000; Main and Lovell, 1996;Sheerin and de Frein, 2007; Walton et al., 1995). Severalstudies examined the effects of duration of immobilization on

1342 AHN ET AL.

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imm

o-

bil

ize

59%

of

pat

ien

ts.T

he

inci

den

ceo

fac

ute

spin

efr

actu

res

for

the

stu

dy

po

pu

lati

on

was

0.3%

.T

his

spin

eas

-se

ssm

ent

pro

toco

lfo

rim

mo

bil

izat

ion

of

trau

ma

pat

ien

tsw

ith

acu

tesp

ine

frac

ture

du

rin

gth

ein

ves

tig

atio

nal

pe-

rio

d,

ren

der

eda

sen

siti

vit

yo

f10

0.0

(95%

CI¼

77.2

,10

0),

an

egat

ive

pre

-d

icti

ve

val

ue

of

100

(95%

CI¼

99.7

,10

0),

asp

ecifi

city

of

41.5

(95%

CI¼

38.5

,43

.5),

and

ap

osi

tiv

e-p

red

icti

ve

val

ue

of

0.5

(95%

CI¼

0.1,

0.9)

.

Bu

rto

net

al.,

2006

J.T

rau

ma

Ast

ate-

wid

e,p

re-

ho

spit

alE

MS

sele

c-ti

ve

pat

ien

tsp

ine

imm

ob

iliz

atio

np

roto

col

Po

pu

lati

on

:31

,885

pat

ien

tsw

ith

mea

nag

eo

f48

.1�

26.7

y(0

–109

y),

45.2

%m

ale.

Tre

atm

ent:

Pre

-ho

spit

alp

rov

id-

ers

do

cum

ente

dE

MS

pat

ien

ten

cou

n-

ters

.F

or

spin

em

anag

emen

t,d

ata

incl

ud

edin

dic

ato

rsfo

rsp

ine

imm

ob

ili-

zati

on

.D

atab

ase

was

qu

erie

dfo

rp

a-ti

ent

enco

un

ters

wit

hIC

D-9

cod

ing

spec

ific

for

the

pre

sen

ceo

fsp

inal

inju

ry.

Ou

tco

me

mea

sure

s:T

he

inci

den

ceo

fsp

ine

frac

ture

sam

on

gE

MS-

asse

ssed

pat

ien

tsan

dco

rrel

atio

nb

etw

een

im-

mo

bil

izat

ion

and

spin

efr

actu

re.

To

eval

uat

eth

ep

ract

ices

and

ou

tco

mes

asso

ciat

edw

ith

ast

ate-

wid

eE

MS

pro

toco

lfo

rtr

aum

ap

a-ti

ent

spin

eas

sess

men

tan

dse

lect

ive

pat

ien

tim

-m

ob

iliz

atio

n

330

12,9

88(4

1%)

tran

spo

rted

wit

hE

MS

spin

eim

mo

bil

izat

ion

.D

ata

lin

kag

eid

enti

-fi

ed15

4sp

ine

frac

ture

sw

ith

20(1

3%)

tran

spo

rted

wit

ho

ut

imm

ob

iliz

atio

n;

19o

fth

ese

wer

est

able

spin

efr

actu

res.

Th

ep

roto

col

sen

siti

vit

yfo

rim

mo

bil

i-za

tio

no

fan

yac

ute

spin

efr

actu

rew

as87

%.

Pre

sen

ceo

fth

ep

roto

col

affe

cted

the

dec

isio

nn

ot

toim

mo

bil

ize

inm

ore

than

hal

fo

fth

eas

sess

edp

atie

nts

.

Ch

an,

etal

.,19

96J.

Em

erg

.M

ed.

Bac

kb

oar

dv

s.m

attr

ess

spli

nt

imm

ob

iliz

a-ti

on

:a

com

par

iso

no

fsy

mp

tom

sg

ener

-at

ed

(Pro

spec

tiv

eR

CT

)P

op

ula

tio

n:

37h

ealt

hy

vo

lun

teer

s.T

rea

tme

nt:

nec

kco

llarþ

bac

kb

oar

dv

ersu

sn

eck

coll

arv

ersu

sv

acu

um

spli

nt.

Ou

tco

me

me

a-

sure

s:se

lf-r

epo

rted

pai

nle

vel

s.

To

com

par

ep

ain

lev

els

be-

twee

nn

eck

col-

larþ

bac

kb

oar

dv

ersu

sn

eck

coll

arþ

vac

uu

msp

lin

t

1B21

Sig

nifi

can

tly

mo

rep

ain

inth

eb

ack

bo

ard

gro

up

(p<

0.00

1),

inp

arti

cula

rin

the

occ

ipit

alre

gio

nan

dth

elu

mb

osa

cral

reg

ion

.

1344

Page 5: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Ch

and

ler

etal

.,19

92A

nn

.E

mer

g.

Med

.E

mer

gen

cyce

rvic

al-

spin

eim

mo

bil

iza-

tio

n

(Exp

erim

enta

l)P

op

ula

tio

n:

Ag

29.6

;%

100.

Tre

atm

ent:

Un

rest

rain

edce

rvic

alm

oti

on

was

com

par

edw

ith

mo

tio

nin

ace

rvic

alex

tric

atio

nco

llar

and

anA

mm

erm

anh

alo

ort

ho

sis

wit

han

dw

ith

ou

ta

spin

eb

oar

d.

In10

sub

ject

sth

era

ng

eo

fm

oti

on

was

mea

-su

red

inth

eA

mm

erm

anh

alo

ort

ho

sis

and

cerv

ical

extr

icat

ion

coll

aral

on

e.In

the

oth

er10

sub

ject

sth

era

ng

eo

fm

oti

on

was

det

erm

ined

wit

hth

ece

r-v

ical

extr

icat

ion

coll

arin

pla

cean

dth

eh

ead

tap

edto

asu

pin

esp

ine

bo

ard

,an

dal

sow

ith

the

Am

mer

man

hal

oo

rth

osi

sat

tach

edto

asu

pin

esp

ine

bo

ard

.O

utc

om

em

easu

res:

Ph

oto

-g

rap

hic

mea

sure

men

to

fh

ead

and

nec

km

oti

on

du

rin

gm

axim

alfl

exio

nex

ten

-si

on=la

tera

lb

end

ing=ro

tati

on

.R

adi-

olo

gic

alm

easu

rem

ent

of

max

imal

inte

rver

teb

ral

flex

ion

-ext

ensi

on

.

To

det

erm

ine

the

effe

ctiv

e-n

ess

of

ace

rvic

alsp

ine

imm

ob

iliz

atio

nu

sin

ga

rig

idce

rvic

alex

tric

atio

nco

llar

and

anA

mm

er-

man

hal

oo

rth

osi

sw

ith

and

wit

ho

ut

spin

eb

oar

ds

Ben

ch-s

ide

ex-

per

imen

tal

stu

dy

17B

oth

the

cerv

ical

extr

icat

ion

coll

aran

dth

eA

mm

erm

anh

alo

ort

ho

sis

sig

nifi

-ca

ntl

yre

du

ced

mo

tio

nin

all

pla

nes

(p<

0.00

1),

wit

hth

eA

mm

erm

anh

alo

ort

ho

sis

red

uci

ng

thes

em

oti

on

ssi

g-

nifi

can

tly

mo

re(p<

0.00

1).

Th

eu

seo

fa

spin

eb

oar

dre

stri

cted

mo

tio

ns

even

mo

re(p<

0.00

1).

Th

eA

mm

erm

anh

alo

ort

ho

sis

wit

ha

spin

eb

oar

dp

ro-

vid

edth

eg

reat

est

imm

ob

iliz

atio

n,

equ

ival

ent

toth

atp

rov

ided

by

ah

alo

-v

est.

Ari

gid

cerv

ical

coll

aran

da

spin

eb

oar

dp

rov

ided

sig

nifi

can

tly

bet

ter

imm

ob

iliz

atio

nth

anth

eco

llar

alo

ne.

Fu

rth

erim

mo

bil

izat

ion

was

pro

vid

edb

yan

Am

mer

man

hal

oo

rth

osi

s.

Co

rdel

let

al.,

1995

An

n.

Em

erg

.M

ed.

Pai

nan

dti

ssu

ein

ter-

face

pre

ssu

res

du

r-in

gsp

ine

bo

ard

imm

ob

iliz

atio

n

(Ex

per

imen

tal

RC

T)

Po

pu

lati

on

:M=F¼

8=12

;A

ge¼

29.9

y(1

6–50

y);

Hei

gh

t¼66

.2in

;W

eig

ht¼

165.

7lb

;A

ver

age

po

un

d-t

o-i

nch

rati

2.5

Tre

atm

en

t:P

re-h

osp

ital

tran

spo

rtco

nd

itio

ns

wer

esi

mu

late

db

yim

mo

-b

iliz

ing

hea

lth

yv

olu

nte

ers

wit

hh

ard

cerv

ical

coll

ars

and

sin

gle

-bu

ckle

ches

tst

rap

so

nw

oo

den

spin

eb

oar

ds

wit

ho

rw

ith

ou

tco

mm

erci

ally

avai

lab

lem

edic

alai

rm

attr

esse

s.T

he

cro

sso

ver

ord

erw

asra

nd

om

ized

.A

fter

80m

in,

the

sub

ject

sw

ere

allo

wed

tog

eto

ffth

eb

oar

ds

for

are

cov

ery

per

iod

of

60m

in.

Su

bje

cts

wer

eth

enst

ud

ied

for

ase

c-o

nd

80-m

inp

erio

dw

ith

the

op

po

site

inte

rven

tio

n.

To

stan

dar

diz

e,v

olu

n-

teer

sw

ere

inst

ruct

edto

wea

rco

m-

fort

able

,lo

ose

-fitt

ing

clo

thin

g.

Bel

ts,

sho

es,

and

all

ob

ject

sin

po

cket

sw

ere

rem

ov

ed.

At

bas

elin

ean

dat

20-m

inin

terv

als,

the

lev

elo

fp

ain

was

rate

dw

ith

a10

0-m

mv

isu

alan

alo

gsc

ale.

Tis

sue

inte

rfac

ep

ress

ure

sw

ere

mea

-su

red

atth

eo

ccip

ut,

sacr

um

,an

dle

fth

eel.

Ou

tco

me

me

asu

res:

Dif

fere

nce

sin

pai

nan

dp

ress

ure

lev

els

bet

wee

nth

etw

otr

eatm

ents

.

To

inv

esti

gat

eth

ele

vel

of

pai

nan

dti

ssu

e-in

terf

ace

pre

ssu

res

inv

olu

nte

ers

imm

ob

iliz

edo

nsp

ine

bo

ard

sw

ith

and

wit

ho

ut

inte

rpo

sed

air

mat

tres

ses

1B28

Th

etw

otr

eatm

ent

typ

esd

idn

ot

dif

fer

sig

nifi

can

tly

inag

e(p¼

0.30

),h

eig

ht

(p¼

0.88

),w

eig

ht

(p¼

0.68

),o

rp

ou

nd

s-to

-in

chra

tio

(p¼

0.5)

.P

ain

lev

els

chan

ged

sig

nifi

can

tly

ov

erti

me

(p¼

0.00

01)

and

the

two

trea

tmen

tsd

iffe

red

inam

ou

nt

of

pai

n(p¼

0.00

01)

and

pat

tern

of

pai

nch

ang

eo

ver

tim

e(p¼

0.00

09).

No

sig

nifi

can

td

iffe

ren

cein

pai

nb

etw

een

the

two

trea

tmen

tsat

tim

e-p

oin

t0;

sub

ject

sre

po

rted

sig

nifi

-ca

ntl

ym

ore

pai

nd

uri

ng

the

no

-m

attr

ess

per

iod

at20

(p¼

0.00

3),

40(p¼

0.00

01),

60(p¼

0.00

01),

and

80m

in(p¼

0.00

01).

Inte

rfac

ep

ress

ure

lev

els

wer

esi

gn

ifica

ntl

yle

ssfo

rm

at-

tres

sth

ann

o-m

attr

ess

atth

eo

ccip

ut

(p¼

0.00

01),

sacr

um

(p¼

0.00

01),

and

hee

l(p¼

0.00

01).

Pre

ssu

rew

assi

gn

ifi-

can

tly

less

du

rin

gth

em

attr

ess

per

iod

atal

lti

me

po

ints

(p¼

0.00

01).

Pai

nle

vel

sfo

rth

em

attr

ess

and

no

-mat

tres

sg

rou

ps

wer

en

ot

sig

nifi

can

tly

dif

fere

nt

on

the

bas

iso

fo

rder

of

trea

tmen

tg

rou

pas

-si

gn

men

t(p¼

0.41

and

0.93

).T

ota

lp

ress

ure

was

rela

ted

toh

eig

ht

(p¼

0.00

8),

and

no

tsi

gn

ifica

ntl

yre

-la

ted

tow

eig

ht

(p¼

0.11

).T

ota

lp

res-

sure

was

no

tsi

gn

ifica

ntl

yre

late

dto

pai

n(p¼

0.76

).

(Con

tin

ued

)

1345

Page 6: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Ta

bl

e1.

Ev

id

en

ce

Ta

bl

e(C

on

tin

ue

d)

Ref

eren

ceJo

urn

alT

itle

Des

ign

Pu

rpos

e=h

yp

oth

esis

Sac

kett

rati

ng

aD

&B

scor

e(o

ut

of44

)R

esu

lts

Co

rnw

ell

etal

.,20

01A

rch

.S

urg

.T

ho

raco

lum

bar

im-

mo

bil

izat

ion

for

trau

ma

pat

ien

tsw

ith

tors

og

un

sho

tw

ou

nd

s

(Obs

erv

atio

nal

case

rep

orts

)P

op

ula

tio

n:

Med

ian

age¼<

25y

;M

ale¼

90.8

%.

Tre

atm

en

t:P

atie

nts

wh

oco

uld

hav

eth

eore

tica

lly

ben

efite

dfr

om

spin

alim

mo

bil

izat

ion

wer

eth

ose

wh

od

idn

ot

hav

eco

mp

lete

neu

rolo

gic

ald

efi-

cits

,an

dw

ho

req

uir

eda

ver

teb

ral

colu

mn

stab

iliz

atio

np

roce

du

rew

hil

ein

the

ho

spit

al.

Pat

ien

ts(1

)w

ith

no

ver

teb

ral

colu

mn

inju

ry,

(2)

wit

hle

ss-

than

-co

mp

lete

neu

rolo

gic

ald

efici

tsb

ut

wit

hst

able

ver

teb

ral

colu

mn

san

dw

ho

did

no

tre

qu

ire

ver

teb

ral

colu

mn

stab

iliz

atio

nw

hil

ein

the

ho

spit

al,

or

(3)

wit

hco

mp

lete

neu

ro-

log

ical

defi

cits

wh

ow

ere

con

sid

ered

ton

ot

hav

eb

enefi

ted

fro

mth

ora

co-

lum

bar

imm

ob

iliz

atio

n.

Ou

tco

me

me

asu

res:

Ap

atie

nt

was

con

sid

ered

toh

ave

ben

efite

dfr

om

imm

ob

iliz

a-ti

on

ifh

eo

rsh

eh

adle

ss-t

han

-co

mp

lete

neu

rolo

gic

ald

efici

tsin

the

pre

sen

ceo

fan

un

stab

lev

erte

bra

lco

lum

n,

assh

ow

nb

yth

en

eed

for

op

erat

ive

stab

iliz

atio

no

fth

ev

erte

bra

lco

lum

n;

mo

rtal

ity

.

To

loo

kat

the

po

ten

tial

ben

efits

and

neg

ativ

eef

-fe

cts

of

tim

ere

qu

ired

for

EM

Sp

roto

col

inp

atie

nts

wit

hto

rso

gu

nsh

ot

wo

un

ds

419

In10

00p

atie

nts

wit

hto

rso

gu

nsh

ot

wo

un

ds,

141

pat

ien

tsh

adv

erte

bra

lco

lum

no

rsp

inal

cord

inju

ry.

Tw

op

atie

nts

req

uir

edo

per

ativ

ev

erte

bra

lco

lum

nst

abil

izat

ion

,w

hil

esi

xo

ther

sre

qu

ired

oth

ersp

inal

op

erat

ion

s(d

e-co

mp

ress

ion=fo

reig

nb

od

yre

mo

val

).T

he

two

pat

ien

tsar

eth

eo

nly

on

esw

ho

wo

uld

hav

eb

enefi

ted

fro

mth

or-

aco

lum

bar

imm

ob

iliz

atio

nin

the

fiel

d.

Pla

cem

ent

on

alo

ng

bo

ard

wit

ho

ut

form

alfo

ur-

po

int

fix

atio

nfo

rp

atie

nts

inth

isca

teg

ory

wo

uld

allo

wa

sho

rter

inju

ry-t

o-t

reat

men

tti

me,

wh

ile

pre

-se

rvin

gth

eb

enefi

tto

thes

etw

op

a-ti

ents

.F

orm

alim

mo

bil

izat

ion

wo

uld

no

th

ave

ben

efite

dth

e73

surv

ivo

rsw

ho

had

com

ple

tele

sio

ns

of

thei

rsp

inal

cord

sn

or

the

859

pat

ien

tsw

ho

had

no

ver

teb

ral

colu

mn

inju

ry.

Th

ep

rese

nce

of

ver

teb

ral

colu

mn

inju

ryw

asac

tual

lyas

soci

ated

wit

hlo

wer

mo

rtal

ity

(7.1

%,

p<

0.02

)th

anp

atie

nts

wit

hn

ov

erte

bra

lco

lum

nin

jury

(14.

8%,

p<

0.02

).

Dav

ies

etal

.,19

96In

jury

Th

eef

fect

of

ari

gid

coll

aro

nin

trac

ra-

nia

lp

ress

ure

(IC

P)

(Obs

erv

atio

nal

case

seri

es)

Tre

atm

en

t:T

he

asse

ssm

ent

of

coll

arfi

tmen

tw

asd

on

eb

ya

sin

gle

op

erat

or

fam

ilia

rw

ith

spin

alim

mo

bil

izat

ion

and

wit

hth

em

anu

fact

ure

r’s

reco

mm

end

edg

uid

e-li

nes

.M

easu

rem

ents

of

intr

acra

nia

lp

ress

ure

,m

ean

arte

rial

pre

ssu

re(M

AP

),h

eart

rate

(HR

),an

dce

ntr

alv

eno

us

pre

ssu

re(C

VP

)w

ere

mad

e20

min

bef

ore

the

coll

arw

asap

pli

ed,

20m

inaf

ter,

and

20m

inaf

ter

itw

asre

mo

ved

.O

utc

om

em

ea

sure

s:p

atie

nt

rep

ort

dat

a.

To

mea

sure

chan

ges

inIC

Pin

pat

ien

tsw

ho

req

uir

edsp

inal

imm

ob

iliz

atio

nb

yp

roto

col,

and

wh

oco

uld

hav

ed

istu

rbed

cere

bra

lau

tore

gu

lati

on

419

Am

ean

ICP

rise

of

4.5

mm

Hg

(SD

4.1

mm

Hg

)w

asfo

un

d.

Ap

aire

dan

aly

sis

of

ICP

read

ing

sw

ith

and

wit

ho

ut

the

coll

arsh

ow

eda

sig

nifi

-ca

nt

rise

wh

enth

eco

llar

was

use

d(p¼<

0.00

1).

Pai

red

anal

ysi

so

fH

R,

CV

P,

and

MA

Pw

ith

and

wit

ho

ut

the

coll

arsh

ow

edn

osi

gn

ifica

nt

dif

fer-

ence

.T

her

ew

asn

oco

rrel

atio

nb

e-tw

een

chan

ges

inIC

Pan

dM

AP

(r¼

0.17

),st

arti

ng

ICP

(r¼

0.03

),ch

ang

ein

CV

P(r¼

0.06

),o

rch

ang

ein

HR

(r¼

0.02

).

1346

Page 7: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

De

Lo

ren

zoet

al.,

1996

An

n.

Em

erg

.M

ed.

Op

tim

alp

osi

tio

nin

gfo

rce

rvic

alim

mo

-b

iliz

atio

n

(Ex

per

imen

tal

non

-RC

T)

Po

pu

lati

on

:M=F¼

8=11

;A

ge¼

33.6

y(2

0–54

y).

Tre

atm

en

t:S

ub

ject

sw

ere

ask

edto

lie

on

ari

gid

pla

stic

bo

ard

.T

he

nec

kw

asfl

exed

and

exte

nd

edb

yra

isin

gan

dlo

wer

ing

the

hea

dre

lati

ve

toth

eco

ccy

x-s

cap

ula

rp

lan

ein

2-cm

incr

e-m

ents

.T

he

mag

net

icfi

eld

iso

cen

ter

was

alig

ned

wit

hth

esu

bje

ct’s

cric

oid

mem

bra

ne.

On

ceth

esu

bje

ctw

asin

po

siti

on

,im

agin

gw

aso

bta

ined

wit

ha

Ph

illi

ps

1.5

Tsc

ann

er.

Tra

nsv

erse

im-

ages

thro

ug

hth

ece

nte

ro

fth

ev

erte

-b

ral

bo

die

sfr

om

C2

toT

2w

ere

ob

tain

ed.

Th

eim

agin

gp

roce

ssw

asre

pea

ted

wit

hth

eo

ccip

ut

seq

uen

tial

lyel

evat

edan

dlo

wer

edb

y2

and

4cm

toth

ep

lan

eo

fth

ep

last

icb

oar

d.

Ou

t-co

me

me

asu

res:

Th

era

tio

of

spin

alca

nal

and

spin

alco

rdar

eas

atea

chsp

inal

lev

elC

2to

T1

was

calc

ula

ted

for

each

po

siti

on

of

flex

ion

and

ex-

ten

sio

n.

Th

ecr

oss

-sec

tio

nal

area

was

det

erm

ined

.

To

det

erm

ine

the

op

tim

alp

osi

tio

nfo

rce

rvic

alsp

ine

imm

ob

iliz

atio

nu

sin

gm

agn

etic

reso

-n

ance

imag

ing

(MR

I),

and

tod

efin

eth

iso

pti

-m

alp

osi

tio

nin

acl

ini-

call

yre

pro

du

cib

lefa

shio

n

419

Th

em

ean

rati

oo

fsp

inal

can

alan

dsp

inal

cord

cro

ss-s

ecti

on

alar

eas

was

smal

lest

atC

6,b

ut

exce

eded

2.0

atal

lle

vel

sfr

om

C2

toT

1(p<

0.05

).A

tC

4–C

7th

eze

rop

osi

tio

nra

tio

of

spi-

nal

can

alar

eato

spin

alco

rdar

eaw

asm

inim

um

for

78%

of

sub

ject

s.S

mal

lca

nal

-to

-co

rdra

tio

sre

pre

sen

tth

elo

wes

tm

arg

ino

fsa

fety

for

inju

ryto

the

spin

alco

rdp

ote

nti

ally

swo

llen

by

inju

ryo

ris

chem

ia,

or

imp

ing

edo

nb

yd

isp

lace

dv

erte

bra

lst

ruct

ure

s.A

tth

eC

5an

dC

6le

vel

sth

em

axim

alar

eara

tio

was

mo

stco

nsi

sten

tly

ob

tain

edw

ith

slig

ht

flex

ion

(cer

vic

al-t

ho

raci

can

gle

of

148;

p<

0.05

).F

or

ap

atie

nt

lyin

gfl

ato

na

bac

kb

oar

d,

this

corr

e-sp

on

ds

tora

isin

gth

eo

ccip

ut

2cm

.A

tþ4

elev

atio

nsi

gn

ifica

nt

var

iab

ilit

yw

aso

bta

ined

amo

ng

the

sub

ject

ssu

chth

atat

this

extr

eme

deg

ree

of

flex

ion

,so

me

ind

ivid

ual

sh

adm

axim

alsp

inal

can

al=sp

inal

cord

area

rati

os

ata

giv

enle

vel

,w

her

eas

oth

ers

had

min

-im

alsp

inal

can

al=sp

inal

cord

area

rati

os.

Inh

ealt

hy

adu

lts,

asl

igh

td

egre

eo

ffl

exio

neq

uiv

alen

tto

2cm

of

occ

ipu

tel

evat

ion

pro

du

ces

afa

vo

r-ab

lein

crea

sein

spin

alca

nal=sp

inal

cord

rati

oat

lev

els

C5

and

C6,

are

gio

no

ffr

equ

ent

un

stab

lesp

ine

inju

ries

.

Do

mei

eret

al.,

1997

Aca

d.

Em

erg

.M

ed.

Pro

spec

tiv

ev

alid

atio

no

fo

ut

of

ho

spit

alsp

inal

clea

ran

cecr

iter

ia:

ap

reli

mi-

nar

yre

po

rt

(Obs

erva

tion

alst

udy

)P

op

ula

tio

n:

M=F¼

1035=10

61;

Lev

elo

fin

jury

:C¼

19;

22;

25.

Tre

atm

en

t:O

ut

of

ho

spit

altr

ansp

ort

amb

ula

nce

per

son

nel

com

ple

ted

aq

ues

tio

nn

aire

for

pat

ien

ts.

All

par

tici

pat

ing

per

-so

nn

elw

ere

trai

ned

on

the

stu

dy

and

qu

esti

on

nai

res.

Th

eyw

ere

told

tov

erif

yth

ep

rese

nce

or

abse

nce

of

each

dat

ap

oin

tb

ased

on

the

init

ial

pat

ien

tev

alu

atio

n.

Th

ep

erso

nn

elw

ere

inst

ruct

edto

det

ail

any

po

ten

-ti

alD

PI.

Ou

tco

me

dat

ap

oin

tsw

ere

det

erm

ined

by

med

ical

reco

rdre

-v

iew

.O

utc

om

em

easu

res:

Pre

sen

ceo

rab

sen

ceo

fa

spin

alfr

actu

reo

rS

CI,

loca

tio

no

ffr

actu

rean

dtr

eat-

men

t.

To

pro

spec

tiv

ely

asse

ssw

het

her

the

abse

nce

of

all

of

the

abo

ve

retr

o-

spec

tiv

ely

iden

tifi

edcr

i-te

ria

can

be

use

dto

iden

tify

ou

to

fh

osp

ital

trau

ma

pat

ien

tsw

ith

ou

tsi

gn

ifica

nt

spin

alfr

actu

re

417

See

text

(Con

tin

ued

)

1347

Page 8: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Ta

bl

e1.

Ev

id

en

ce

Ta

bl

e(C

on

tin

ue

d)

Ref

eren

ceJo

urn

alT

itle

Des

ign

Pu

rpos

e=h

yp

oth

esis

Sac

kett

rati

ng

aD

&B

scor

e(o

ut

of44

)R

esu

lts

Do

mei

eret

al.,

1999

Pre

ho

sp.

Em

erg

.C

are

Th

ere

liab

ilit

yo

fp

re-

ho

spit

alcl

inic

alev

alu

atio

nfo

rp

o-

ten

tial

spin

alin

jury

isn

ot

affe

cted

by

the

mec

han

ism

of

inju

ry

(Cas

ese

ries

)T

rea

tme

nt:

Pre

-ho

spit

altr

ansp

ort

ing

amb

ula

nce

pro

vid

ers

com

ple

ted

ad

ata

qu

esti

on

nai

refo

ral

lth

ep

atie

nts

wh

om

etth

est

ud

yp

op

-u

lati

on

incl

usi

on

crit

eria

.A

llp

arti

ci-

pat

ing

pre

-ho

spit

alp

erso

nn

elw

ere

pro

vid

edb

rief

did

acti

ctr

ain

ing

de-

sig

ned

for

ori

enta

tio

nto

the

stu

dy

and

dat

aco

llec

tio

nsh

eet.

Par

tici

pan

tsw

ere

inst

ruct

edto

det

erm

ine

the

pre

sen

ceo

rab

sen

ceo

fea

chd

ata

po

int

bas

edo

nth

ein

itia

lp

atie

nt

eval

uat

ion

.T

he

dat

aq

ues

tio

nn

aire

sw

ere

left

inth

eE

Do

fth

ere

ceiv

ing

faci

lity

,o

rg

iven

toth

eam

bu

lan

cesu

per

vis

or

for

dis

trib

uti

on

and

ou

tco

me

det

erm

inat

ion

.O

utc

om

em

easu

res:

Pre

sen

ceo

rab

sen

ceo

fsp

i-n

alfr

actu

reo

rS

CI,

loca

tio

no

ffr

actu

rean

dtr

eatm

ent.

To

exam

ine

the

effe

cto

fth

ese

ver

ity

of

the

mec

ha-

nis

mo

fin

jury

on

the

abil

ity

of

clin

ical

crit

eria

tose

lect

pat

ien

tsw

ith

spin

alin

jury

427

See

tex

t

Do

mei

er,

etal

.,20

02J.

Tra

um

aM

ult

icen

ter

pro

spec

tiv

ev

alid

a-ti

on

of

pre

-ho

spit

alcl

inic

alsp

inal

clea

ran

cecr

iter

ia

(Cas

ese

ries

)P

op

ula

tio

n:

%M=F¼

49.5=50

.5;

Ag

39.3

y;

Lev

elo

fin

jury

:C¼

109;

86;

100.

Tre

atm

en

t:P

re-h

osp

ital

tran

spo

rtin

gam

bu

lan

cep

rov

ider

sw

ere

inst

ruct

edto

com

ple

tea

stan

dar

diz

edd

ata

qu

esti

on

nai

refo

ral

lp

atie

nts

wh

om

etin

clu

sio

ncr

iter

ia.

All

par

tici

pat

ing

pre

-ho

spit

alp

erso

nn

elw

ere

pro

vid

eda

bri

efd

idac

tic

trai

nin

gse

ssio

nd

e-si

gn

edfo

ro

rien

tati

on

toth

est

ud

yan

dd

ata

coll

ecti

on

shee

tb

efo

reen

roll

ing

pat

ien

ts.

Ou

tco

me

me

asu

res:

Pat

ien

tre

po

rtd

ata.

To

pro

spec

tiv

ely

val

idat

eth

atth

eab

sen

ceo

fsp

e-ci

fic

crit

eria

can

be

use

dto

iden

tify

pre

-ho

spit

altr

aum

ap

atie

nts

wit

ho

ut

asp

inal

inju

ry,

and

wh

od

on

ot

req

uir

ep

re-

ho

spit

alri

gid

imm

ob

ili-

zati

on

415

See

tex

t

Do

mei

eret

al.,

2005

An

n.

Em

erg

.M

ed.

Pro

spec

tiv

ep

erfo

r-m

ance

asse

ssm

ent

of

ano

ut

of

ho

spi-

tal

pro

toco

lfo

rse

-le

ctiv

esp

ine

imm

ob

iliz

atio

nu

s-in

gcl

inic

alsp

ine

clea

ran

cecr

iter

ia

(Cas

ese

ries

)P

op

ula

tio

n:

Ag

e¼<

1–10

4y

;L

evel

of

inju

ry:

27%

C,

10%

T,

2.5%

L.

Tre

atm

en

t:E

MS

per

son

nel

wer

etr

ain

edto

per

form

and

do

cum

ent

asp

ine

inju

ryas

sess

men

tfo

ro

ut-

of-

ho

spit

altr

aum

ap

atie

nts

wit

ha

mec

han

ism

of

inju

ryju

dg

edsu

ffici

ent

toca

use

asp

ine

inju

ry.

Ou

tco

me

me

asu

res:

Bas

edo

nh

osp

ital

reco

rds

and

spin

ein

jury

asse

ssm

ent

tab

leco

mp

lete

db

yE

MS

per

son

nel

.O

ut-

com

ech

arac

teri

stic

sin

clu

ded

the

pre

sen

ceo

rab

sen

ceo

fsp

ine

inju

ryan

dsp

ine

inju

rym

anag

emen

t.

To

det

erm

ine

wh

eth

erth

eu

seo

fan

EM

Sp

roto

col

for

sele

ctiv

esp

ine

im-

mo

bil

izat

ion

wo

uld

resu

ltin

app

rop

riat

eim

mo

bil

izat

ion

wit

ho

ut

SC

Ias

soci

ated

wit

hn

oim

mo

bil

izat

ion

415

See

tex

t

1348

Page 9: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Do

ran

etal

.,19

95P

reh

osp

.D

isas

-te

rM

ed.

Fac

tors

infl

uen

cin

gsu

cces

sfu

lin

tub

a-ti

on

inth

ep

re-

ho

spit

alse

ttin

g

(Pro

spec

tiv

ere

vie

w)

Po

pu

lati

on

:46

91p

a-ti

ents

tran

spo

rted

;23

6w

ith

intu

bat

ion

atte

mp

ts;

78%

mal

e,m

ean

age

51.4�

22.1

0y

.T

rea

tme

nt:

Dat

aab

-st

ract

edfr

om

run

rep

ort

san

dp

ara-

med

ics

ask

edin

stru

ctu

red

inte

rvie

ws

tod

escr

ibe

dif

ficu

ltie

sin

OE

TI=

ET

I.O

utc

om

em

easu

res:

Su

cces

so

rfa

ilu

reo

fp

re-h

osp

ital

intu

bat

ion

To

exp

lore

the

det

erm

i-n

ants

infl

uen

cin

go

ral=

nas

alen

do

trac

hea

lin

tub

atio

n;

tod

eter

min

ew

hic

hco

gn

itiv

e,th

era-

peu

tic,

and

tech

nic

alin

-te

rven

tio

ns

may

assi

stp

re-h

osp

ital

airw

aym

anag

emen

t

2B25

88%

succ

essf

ul

intu

bat

ion

;p

osi

tio

nan

dsp

inal

imm

ob

iliz

atio

nw

ere

rep

ort

edto

incr

ease

dif

ficu

lty

in39

.6%

of

trau

ma

pat

ien

ts.

Fla

bo

uri

s,20

01In

jury

Cli

nic

alfe

atu

res,

pat

-te

rns

of

refe

rral

and

ou

to

fh

osp

ital

tran

spo

rtev

ents

for

pat

ien

tsw

ith

sus-

pec

ted

iso

late

dsp

i-n

alin

jury

(Cas

ese

ries

)P

op

ula

tio

n:

Ag

31y

;%

68;

Lev

elo

fin

jury

:C¼

41%

;L¼

10%

;T¼

8%;

mix

ed¼

2%;

no

r-m

al¼

39%

.T

rea

tme

nt:

Med

ical

tran

s-p

ort

reco

rds

of

pat

ien

tstr

ansp

ort

edw

ere

rev

iew

ed.

Rel

evan

td

ata

wer

eco

llat

edo

nto

ast

ud

y-s

pec

ific

dat

a-b

ase.

Ou

tco

me

me

asu

res:

Pat

ien

td

emo

gra

ph

ics,

typ

ean

dm

od

eo

ftr

ansp

ort

,an

dtr

ansp

ort

inci

den

ts.

Sce

ne,

pre

-ref

erra

l,an

do

utc

om

ecl

in-

ical

dat

a.

To

des

crib

eth

ep

atte

rno

fu

tili

zati

on

of

ap

atie

nt

tran

spo

rtat

ion

serv

ice

by

pat

ien

tsw

ith

susp

ecte

dis

ola

ted

spin

alin

juri

esw

ho

are

tran

spo

rted

fro

mh

osp

ital=sc

ene,

do

cum

ent

the

imp

act

of

the

serv

ice

on

scen

em

anag

emen

tan

dth

ecl

inic

alco

sto

fm

od

eso

ftr

ansp

ort

atio

n

419

See

text

Ger

lin

get

al.,

2000

An

n.

Em

erg

.M

ed.

Eff

ects

of

cerv

ical

spin

eim

mo

bil

iza-

tio

nte

chn

iqu

ean

dla

ryn

go

sco

pe

bla

de

sele

ctio

no

nan

un

-st

able

cerv

ical

spin

ein

aca

dav

erm

od

elo

fin

tub

atio

n

(Ex

per

imen

tal)

Tre

atm

en

t:A

C5–

C6

sur-

gic

altr

anse

ctio

nw

ascr

eate

dto

stan

dar

diz

eth

em

od

elo

fin

jury

.A

nan

teri

or

app

roac

hw

asse

lect

ed,

wit

ha

ver

tica

lin

cisi

on

mad

eal

on

gth

em

e-d

ial

asp

ect

of

the

clav

icu

lar

hea

do

fth

est

ern

ocl

eid

om

asto

idm

usc

le.C

om

ple

tein

stab

ilit

yo

fth

ein

jury

was

con

firm

edth

rou

gh

flu

oro

sco

py

asd

efin

edb

yan

gu

lar

dis

pla

cem

ent>

118

and

AP

dis

pla

cem

ent>

20%

of

C5

ver

teb

ral

bo

dy

wid

thd

uri

ng

man

ipu

lati

on

.A

nO

TI

was

per

form

edw

ith

each

of

the

thre

ela

ryn

go

sco

pe

bla

des

.E

ach

of

the

two

dif

fere

nt

imm

ob

iliz

atio

nte

ch-

niq

ues

(man

ual

in-l

ine

stab

iliz

atio

nan

dce

rvic

alco

llar

imm

ob

iliz

atio

n)

wer

eal

sou

sed

.A

cro

ss-o

ver

des

ign

was

use

din

wh

ich

thre

eb

lad

esan

db

oth

imm

ob

iliz

atio

nte

chn

iqu

esw

ere

use

din

ran

do

mo

rder

for

each

ca-

dav

er.

Intu

bat

ors

wer

en

ot

bli

nd

edto

eith

erth

eb

lad

ety

pe

or

imm

ob

iliz

a-ti

on

tech

niq

ue.

Ou

tco

me

me

asu

res:

Am

ou

nt

of

mo

vem

ent

acro

ssth

eu

n-

stab

lece

rvic

alsp

ine

lesi

on

inth

ree

pla

nes

,ax

ial

dis

trac

tio

n,

and

ang

ula

rro

tati

on

To

eval

uat

eth

eef

fect

so

fm

anu

alin

-lin

est

abil

iza-

tio

nan

dce

rvic

alco

llar

imm

ob

iliz

atio

nan

dth

ree

dif

fere

nt

lary

ng

o-

sco

pe

bla

des

on

cerv

ical

spin

em

ov

emen

td

uri

ng

OT

Iin

aca

dav

erm

od

elo

fce

rvic

alsp

ine

inju

ry

Bio

mec

han

ical

stu

dy

,n

ot

app

lica

ble

16S

ign

ifica

ntl

yle

ssm

ov

emen

td

uri

ng

OT

Iw

aso

bse

rved

wit

hth

eu

seo

fm

anu

alin

-lin

est

abil

izat

ion

than

cerv

ical

coll

arim

mo

bil

izat

ion

wit

hre

gar

dto

AP

dis

pla

cem

ent

into

the

spin

alca

nal

(7.5

%v

ersu

s13

.7%

of

C5

bo

dy

wid

th;

0.03

).T

her

ew

ere

no

sig

nifi

can

td

iffe

ren

ces

inax

ial

dis

trac

tio

n=

ang

ula

rro

tati

on

;S

ign

ifica

ntl

yle

ssm

ov

emen

td

uri

ng

OT

Iw

ith

the

use

of

the

Mil

ler

stra

igh

tb

lad

ev

ersu

sth

eM

cIn

tosh

or

CL

Mb

lad

esin

axia

ld

istr

acti

on

(p¼

0.00

9).

Th

ere

wer

en

od

iffe

ren

ces

amo

ng

the

bla

des

inA

Pd

isp

lace

men

to

ran

gu

lar

rota

tio

n.

Th

eC

orm

ack

-Leh

ane

gra

de

ob

tain

edd

ur-

ing

lary

ng

osc

op

yw

assi

gn

ifica

ntl

yb

ette

rw

ith

man

ual

in-l

ine

stab

iliz

a-ti

on

ver

sus

cerv

ical

coll

arim

mo

bil

i-za

tio

n(p<

0.05

),b

ut

no

dif

fere

nce

ing

rad

eb

etw

een

the

Mil

ler,

Mac

into

sh,

and

CL

Mla

ryn

go

sco

pe

bla

des

.

(Con

tin

ued

)

1349

Page 10: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Ta

bl

e1.

Ev

id

en

ce

Ta

bl

e(C

on

tin

ue

d)

Ref

eren

ceJo

urn

alT

itle

Des

ign

Pu

rpos

e=h

yp

oth

esis

Sac

kett

rati

ng

aD

&B

scor

e(o

ut

of44

)R

esu

lts

Gra

zian

oet

al.,

1987

An

n.

Em

erg

.M

ed.

Ara

dio

gra

ph

icco

m-

par

iso

no

fp

re-

ho

spit

alce

rvic

alim

mo

bil

izat

ion

met

ho

ds

(Ex

per

imen

tal

RC

T)

Po

pu

lati

on

:A

ge¼

25y

(18–

61y

)T

rea

tme

nt:

All

vo

lun

teer

sw

ere

test

edin

the

sitt

ing

po

siti

on

toap

pro

xim

ate

the

con

dit

ion

freq

uen

tly

enco

un

tere

din

the

pre

-h

osp

ital

sett

ing

.A

llim

mo

bil

izat

ion

tech

niq

ues

wer

ead

min

iste

red

acco

rd-

ing

toth

em

anu

fact

ure

r’s

reco

m-

men

ded

pro

ced

ure

.E

ach

vo

lun

teer

un

der

wen

tn

ine

rad

iog

rap

hic

vie

ws.

Th

ree

vie

ws

wer

eo

bta

ined

inea

cho

fth

efo

llo

win

gco

nd

itio

ns

stu

die

d:

un

-re

stri

cted

for

bas

elin

eco

mp

aris

on

,th

esh

ort

-bo

ard

tech

niq

ue,

and

on

eo

fth

eth

ree

test

dev

ices

tow

hic

hth

esu

bje

ctw

asra

nd

om

lyas

sig

ned

.T

he

effi

caci

eso

fth

ese

tech

niq

ues

wer

eco

mp

ared

.O

utc

om

em

easu

res:

Effi

cacy

of

the

dif

fere

nt

test

dev

ices

To

eval

uat

eth

eef

fica

cyo

fth

ree

new

erco

mm

on

lyu

sed

cerv

ical

imm

ob

ili-

zati

on

dev

ices

(CS

C,

ao

ne-

pie

cew

rap

-aro

un

dco

llar

;K

ED

,a

fact

ory

-fa

bri

cate

dsh

ort

bo

ard

;an

dX

P-O

ne,

afa

cto

ry-

fab

rica

ted

sho

rtb

oar

d-

coll

arco

mb

inat

ion

)fo

rw

hic

hth

ere

are

no

ob

-je

ctiv

ed

ata

pu

bli

shed

inth

em

edic

alli

tera

ture

420

Th

esh

ort

bo

ard

tech

niq

ue

(SB

T)

was

sup

erio

rto

the

CS

Cin

rota

tio

nan

dth

eK

ED

inex

ten

sio

n;

the

KE

Dw

assu

-p

erio

rto

the

SB

Tin

flex

ion

.F

or

tota

lra

ng

eo

fm

oti

on

inth

esa

git

tal

pla

ne

the

SB

Tp

rov

edsi

gn

ifica

ntl

yb

ette

r(p<

0.05

)th

anth

eC

SC

,w

hil

eth

eK

ED

and

XP

-On

eap

pro

ach

edS

BT

effi

cacy

.T

he

SB

Tw

assi

gn

ifica

ntl

yd

iffe

ren

tth

anth

eco

ntr

ols

(p<

0.00

1)in

all

pla

nes

.T

hu

sw

her

ed

iffe

ren

ces

wer

esi

gn

ifica

nt

(p<

0.05

)th

eS

BT

was

sup

erio

rw

hen

com

par

edto

all

test

dev

ices

.T

he

SB

Tw

assu

per

ior

inal

lp

lan

eso

fce

rvic

alsp

ine

mo

tio

n.

Of

the

thre

ed

evic

esco

mp

ared

agai

nst

the

SB

T,

the

sho

rt-b

oar

dd

evic

es(K

ED

and

XP

-On

e)p

rov

ided

the

gre

ates

tim

mo

bil

izat

ion

wit

hlo

gis

tica

lad

van

-ta

ges

ov

erth

eS

BT

.H

amil

ton

and

Po

ns,

1996

J.E

mer

g.

Med

.T

he

effi

cacy

and

com

fort

of

full

bo

dy

vac

uu

msp

lin

tsfo

rce

rvic

al-

spin

eim

mo

bil

iza-

tio

n

Po

pu

lati

on

:A

ge¼

28.9

y;

M=F¼

22=4;

Hei

gh

t¼17

4.5

cm;

Wei

gh

t¼75

.6k

g.

Tre

atm

en

t:E

ach

mea

sure

men

tw

asre

pea

ted

thre

eti

mes

and

the

aver

age

was

use

d.

Su

bje

cts

wer

eas

ked

top

erfo

rmth

ed

esir

edm

oti

on

by

mo

v-

ing

asfa

ras

po

ssib

lew

ith

ou

tca

usi

ng

pai

n=d

isco

mfo

rt.

C-s

pin

eR

OM

was

reco

rded

,aS

tifn

eck

cerv

ical

coll

arw

asap

pli

ed,

and

RO

Mw

asre

pea

ted

.S

ub

ject

sw

ere

then

ran

do

miz

edto

be

imm

ob

iliz

edo

na

stan

dar

dlo

ng

spin

eb

oar

do

ro

nth

eV

acB

oar

d,

bo

thw

ith

and

wit

ho

ut

ace

rvic

alco

llar

.E

ach

sub

ject

was

then

cro

ssed

ov

erto

the

oth

erd

evic

e.D

uri

ng

each

imm

ob

ili-

zati

on

,a

full

set

of

cerv

ical

spin

eR

OM

mea

sure

men

tsw

asm

ade,

and

afte

r10

min

of

imm

ob

iliz

atio

n,

each

sub

ject

was

ask

edto

gra

de

ov

eral

lim

mo

bil

i-za

tio

no

na

10-p

oin

tv

isu

alan

alo

gsc

ale,

wit

h0

as‘‘n

ore

stri

ctio

n’’

and

10as

‘‘co

mp

lete

lyim

mo

bil

ized

.’’S

ub

ject

sw

ere

also

ask

edto

gra

de

dis

com

fort

bo

tho

ver

all

and

inse

ven

spec

ific

bo

dy

reg

ion

so

na

10-p

oin

tv

isu

alan

alo

gsc

ale,

wit

h0

as‘‘n

od

isco

mfo

rt’’

and

10as

‘‘sev

ere

pai

n.’’

Ou

tco

me

me

asu

res:

Sig

nifi

can

ceo

fea

chim

mo

-b

iliz

atio

nsy

stem

on

mo

tio

n,

ov

eral

lim

mo

bil

izat

ion

,an

dd

isco

mfo

rt

To

det

erm

ine

wh

eth

ero

rn

ot

vac

uu

msp

lin

tsp

ro-

vid

ece

rvic

alsp

ine

im-

mo

bil

izat

ion

com

par

able

toth

ato

bta

ined

wit

hth

eri

gid

bac

kb

oar

d,

and

toco

mp

are

the

sub

ject

ive

com

fort

bet

wee

nth

etw

osy

stem

s

2B16

Infl

exio

n,

ther

ew

asn

osi

gn

ifica

nt

dif

-fe

ren

ceb

etw

een

the

VSþ

CC

(vac

uu

msp

lin

tan

dce

rvic

alco

llar

)an

dth

eB

CC

(bac

kb

oar

dan

dce

rvic

alco

llar

),an

db

oth

thes

esy

stem

sp

ro-

vid

edb

ette

rim

mo

bil

izat

ion

than

ei-

ther

wit

ho

ut

the

CC

.W

ith

ou

tth

eC

C,

the

VS

pro

vid

edsi

gn

ifica

ntl

yb

ette

rim

mo

bil

izat

ion

for

flex

ion

than

the

BB

.F

or

exte

nsi

on

,th

eB

Bal

on

ean

dth

eV

Sw

ith

or

wit

ho

ut

aC

Cp

rov

ided

com

-p

arab

leim

mo

bil

izat

ion

,an

dal

lth

ree

com

bo

sw

ere

bet

ter

than

the

BBþ

CC

.In

late

ral

ben

din

g,

the

vac

uu

msp

lin

tin

gen

eral

pro

vid

edb

ette

rim

mo

bil

i-za

tio

nth

anth

eb

ack

bo

ard

,w

ith

or

wit

ho

ut

aC

C.

Inro

tati

on

,th

ere

wer

en

osi

gn

ifica

nt

dif

fere

nce

sin

imm

o-

bil

izat

ion

.S

ign

ifica

nt

dif

fere

nce

sin

sub

ject

per

cep

tio

no

fo

ver

all

imm

ob

i-li

zati

on

wer

efo

un

d,

wit

hth

eV

CC

pro

vid

ing

the

bes

tim

mo

bil

izat

ion

,fo

llo

wed

by

the

BBþ

CC

and

VS

alo

ne,

foll

ow

edb

yth

eB

Bal

on

e.T

he

vac

uu

msp

lin

tw

asal

sofo

un

dto

be

sig

nifi

can

tly

mo

reco

mfo

rtab

leth

anth

eb

ack

bo

ard

,b

oth

insu

bje

ctiv

ep

er-

cep

tio

no

fo

ver

all

and

occ

ipit

alre

gio

nco

mfo

rt,

wit

ho

rw

ith

ou

ta

CC

.

1350

Page 11: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Hau

swal

det

al.,

1998

Aca

d.

Em

erg

.M

ed.

Ou

to

fh

osp

ital

spin

alim

mo

bil

izat

ion

:it

sef

fect

on

neu

rolo

gic

inju

ry

(Obs

ervat

ion

alca

sese

ries

)P

op

ula

tio

n:

Ag

e:¼

34y

(US

A),

(Mal

aysi

a)¼

35y

;%

M(U

SA)¼

77,

(Mal

aysi

a)¼

88;

Lev

elo

fin

jury

:(U

SA)

34%

,T¼

32%

,L¼

34%

;M

alay

sia:

33%

,T¼

28%

,L¼

39%

.T

reatm

ent:

Are

tro

spec

tiv

ech

art

rev

iew

was

con

du

cted

on

all

pat

ien

tsad

mit

ted

toth

ein

pat

ien

tse

rvic

eo

rE

Dfo

rth

etw

oh

osp

ital

s.N

on

eo

fth

ep

atie

nts

seen

atth

eU

niv

ersi

tyo

fM

alay

ah

adsp

inal

imm

ob

iliz

atio

nd

uri

ng

tran

spo

rt,

wh

erea

sal

lth

ep

a-ti

ents

seen

atth

eU

niv

ersi

tyo

fN

ewM

exic

od

id.

Neu

rolo

gic

alin

juri

esw

ere

assi

gn

edto

two

cate

go

ries

(dis

abli

ng

or

no

td

isab

lin

g),

by

two

ph

ysi

cian

sac

t-in

gin

dep

end

entl

yan

db

lin

ded

toth

eh

osp

ital

of

ori

gin

.D

ata

wer

ean

aly

zed

usi

ng

mu

ltiv

aria

telo

gis

tic

reg

ress

ion

.O

utc

om

em

easu

res:

Ch

art

dat

a

To

exam

ine

the

effe

cto

fem

erg

ency

imm

ob

iliz

a-ti

on

on

neu

rolo

gic

alo

utc

om

eo

fp

atie

nts

wh

oh

ave

blu

nt

trau

mat

icsp

inal

inju

ries

423

OR

for

dis

abil

ity

was

hig

her

for

pat

ien

tsin

the

US

Aaf

ter

adju

stm

ent

for

the

effe

cto

fin

dep

end

ent

var

iab

les

(p¼

0.04

).T

he

lev

elo

fn

euro

log

ical

defi

cit

was

the

on

lyin

dep

end

ent

pre

-d

icto

ro

fb

ado

utc

om

e.T

her

ew

asle

ssn

euro

log

ical

dis

abil

ity

inth

eu

nim

-m

ob

iliz

edM

alay

sian

pat

ien

ts(O

R2.

03;

95%

CI

1.03

,3.

99;

0.04

).T

his

corr

esp

on

ds

toa<

2%ch

ance

that

imm

ob

iliz

atio

nis

ben

efici

al.

Res

ult

sw

ere

sim

ilar

wh

enli

mit

edto

pat

ien

tsw

ith

cerv

ical

inju

ries

(OR

1.52

;95

%C

I0.

64,

3.62

;p¼

0.34

).O

ut-

of-

ho

spit

alim

mo

bil

izat

ion

has

litt

leo

rn

oef

fect

on

neu

rolo

gic

alo

utc

om

ein

pat

ien

tsw

ith

blu

nt

spin

alin

juri

es.

Hau

swal

det

al.,

2000

Pre

ho

sp.

Em

erg

.C

are

Max

imiz

ing

com

fort

and

min

imiz

ing

isch

emia

:A

com

-p

aris

on

of

fou

rm

eth

od

so

fsp

inal

imm

ob

iliz

atio

n

(Ex

per

imen

tal

RC

T)

Tre

atm

ent:

Stu

den

tsw

ere

ask

edto

lay

sup

ine

on

fou

rd

iffe

ren

tsu

rfac

esw

ith

ou

tb

ein

gse

cure

dw

ith

stra

ps.

Dev

ices

(tra

dit

ion

alb

ack

-b

oar

d;b

ack

bo

ard

pad

ded

wit

ha

fold

edb

lan

ket

;b

ack

bo

ard

pad

ded

wit

ha

3-cm

gu

rney

mat

tres

s;an

da

bac

kb

oar

dan

dm

attr

ess

pad

ded

wit

ha

6-cm

egg

crat

efo

amp

ad)

wer

eas

sig

ned

inra

nd

om

ord

er.

Aft

erly

ing

for

10m

in,

stu

den

tsra

ted

com

fort

.A

llfo

ur

met

ho

ds

wer

eev

alu

ated

usi

ng

the

sam

esc

ale

toal

low

com

par

iso

no

fre

spo

nse

s.E

ach

par

tici

-p

ant

eval

uat

edal

lfo

ur

dev

ices

and

was

giv

ena

15-m

inre

stin

terv

alb

etw

een

tria

ls.

Eac

hm

ark

ed10

-cm

vis

ual

anal

og

scal

ew

asm

easu

red

on

two

sep

arat

eo

ccas

ion

sto

the

clo

sest

0.1

cmb

yth

esa

me

ob

serv

eran

dth

em

ean

of

thes

etw

oes

tim

ates

was

reco

rded

.O

utc

om

em

easu

res:

Dev

ice

com

fort

sco

res

To

det

erm

ine

wh

ich

of

fou

rm

eth

od

so

fsp

inal

im-

mo

bil

izat

ion

cau

ses

the

leas

tis

chem

icp

ain

2B29

Co

mfo

rtsc

ore

sw

ere

sig

nifi

can

tly

dif

fer-

ent

for

all

met

ho

ds

(F¼

101,

p<

0.00

1).

Ab

ack

bo

ard

pad

ded

wit

ha

gu

rney

mat

tres

san

deg

gcr

ate

foam

cau

sed

the

leas

tis

chem

icp

ain

(9.6

cm,

95%

CI

8.9,

9.8

cm).

Ab

ack

bo

ard

pad

ded

wit

ha

gu

rney

mat

tres

sw

asth

ese

con

dm

ost

com

fort

able

dev

ice

(7.0

cm,

95%

CI

6.4,

7.4

cm).

Ab

ack

bo

ard

pad

ded

wit

ha

fold

edb

lan

ket

was

the

thir

dm

ost

com

fort

able

(3.3

cm,

95%

CI

2.6,

4.9

cm).

Th

eb

ack

bo

ard

alo

ne

cau

sed

the

mo

stp

ain

(0.8

cm,

95%

CI,

0.7

to2.

1cm

).In

crea

sin

gth

eam

ou

nt

of

pad

din

go

na

bac

kb

oar

dd

ecre

ased

the

amo

un

to

fis

chem

icp

ain

cau

sed

by

imm

ob

iliz

atio

n.

Hu

erta

etal

.,19

87A

nn

.E

mer

g.

Med

.C

erv

ical

spin

est

abil

i-za

tio

nin

pae

dia

tric

pat

ien

ts:

eval

uat

ion

of

curr

ent

tech

-n

iqu

es

(Ex

per

imen

tal

Non

-RC

T)

Po

pu

lati

on

:A

ge¼

5–9

y.

Tre

atm

ent:

Eac

hch

ild

was

inst

ruct

edto

exer

tm

axim

um

pre

ssu

rew

ith

his

or

her

hea

dag

ain

sta

stat

ion

ary

han

d-h

eld

blo

od

pre

ssu

recu

ffin

flat

edto

ab

asel

ine

pre

ssu

reo

f20

mm

Hg

.A

ver

age

pre

ssu

res

wer

ed

eter

min

edfo

rea

chd

irec

tio

nan

dth

ese

pre

ssu

res

wer

esu

bse

qu

entl

yre

pro

du

ced

the

man

ne-

qu

ins.

Wit

hth

em

ann

equ

inin

the

sup

ine

po

siti

on

,eac

hce

rvic

alco

llar

was

pla

ced

wit

hm

anu

alax

ial

trac

tio

nan

dim

mo

bil

izat

ion

was

mai

nta

ined

.O

ut-

com

em

easu

res:

Pre

ssu

res

wer

ere

-co

rded

info

ur

dir

ecti

on

s:fl

exio

n,

exte

nsi

on

,to

rsio

n,

and

late

rall

y.

Ov

eral

lef

fect

iven

ess

of

the

coll

arw

asas

sess

ed

Th

isst

ud

yw

asco

nd

uct

edto

eval

uat

eth

eef

fica

cyo

fco

mm

erci

ally

avai

l-ab

lece

rvic

alsp

ine

stab

i-li

zati

on

dev

ices

des

ign

edfo

rp

aed

iatr

icp

atie

nts

417

Co

llar

so

fri

gid

pla

stic

con

stru

ctio

np

er-

form

edb

ette

rth

anfo

am.

Wh

enu

sed

alo

ne

no

ne

of

the

coll

ars

pro

vid

edac

cep

tab

leim

mo

bil

izat

ion

;th

eb

est

allo

wed

178

of

flex

ion

,198

of

exte

n-

sio

n,

48o

fro

tati

on

,an

d68

of

late

ral

mo

tio

n,

bu

tco

mb

ined

wit

ho

ther

de-

vic

es,

imm

ob

iliz

atio

nto

38o

rle

ssin

any

dir

ecti

on

was

ach

iev

ed.

Ov

eral

l,co

mb

inat

ion

met

ho

ds

wer

eb

ette

rth

ance

rvic

alco

llar

sal

on

e(p<

0.00

1)o

rsu

pp

lem

enta

ld

evic

esal

on

e(p<

0.05

).T

he

mo

difi

edh

alf

spin

eb

oar

du

sed

wit

ha

rig

idco

llar

and

tap

ew

asth

em

ost

effe

ctiv

eco

mb

inat

ion

met

ho

d.

(Con

tin

ued

)

1351

Page 12: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Ta

bl

e1.

Ev

id

en

ce

Ta

bl

e(C

on

tin

ue

d)

Ref

eren

ceJo

urn

alT

itle

Des

ign

Pu

rpos

e=h

yp

oth

esis

Sac

kett

rati

ng

aD

&B

scor

e(o

ut

of44

)R

esu

lts

Joh

nso

net

al.,

1996

Am

.J.

Em

erg

.M

ed.

Co

mp

aris

on

of

av

ac-

uu

msp

lin

td

evic

eto

ari

gid

bac

k-

bo

ard

for

spin

alim

mo

bil

izat

ion

(Ex

per

imen

tal)

Tre

atm

en

t:T

oev

alu

ate

the

com

fort=

spee

do

fap

pli

cati

on

of

each

dev

ice,

stu

den

tsw

ere

giv

entr

ain

ing

inth

eu

seo

fea

chd

evic

ean

dal

low

ed4–

6h

of

pra

ctic

e.A

nin

stru

c-to

rti

med

each

pro

ced

ure

and

stu

den

tsw

ere

ran

do

mly

assi

gn

edfo

rp

lace

-m

ent

on

the

vac

uu

msp

lin

to

rth

ew

oo

db

ack

bo

ard

firs

t.A

fter

lyin

go

nea

chd

evic

efo

r30

min

the

stu

den

tsra

ted

com

fort

.E

ach

par

tici

pan

th

adth

eo

pp

ort

un

ity

toev

alu

ate

bo

thd

e-v

ices

.T

he

seco

nd

ph

ase

com

par

edim

mo

bil

izat

ion

of

sub

ject

sin

each

of

the

dev

ices

.Wh

enim

mo

bil

izat

ion

was

mea

sure

d,

each

dev

ice

was

eval

uat

edb

oth

wit

han

dw

ith

ou

tth

eap

pli

cati

on

of

ari

gid

cerv

ical

coll

ar.

Ou

tco

me

me

asu

res:

Co

mfo

rt,

late

ral

tilt

,m

ov

e-m

ent

To

com

par

ea

vac

uu

msp

lin

tm

attr

ess

toa

stan

dar

dw

oo

den

bac

k-

bo

ard

wit

hre

spec

tto

pat

ien

tco

mfo

rt;

also

toco

mp

are

the

two

dev

ices

wit

hre

gar

dto

the

ade-

qu

acy

of

imm

ob

iliz

atio

nan

dsp

eed

of

app

lica

tio

nu

sin

gh

um

anv

olu

nte

ers

417

Th

ev

acu

um

spli

nt

was

sig

nifi

can

tly

mo

reco

mfo

rtab

leo

na

10-p

oin

tsc

ale

than

the

rig

idb

ack

bo

ard

afte

rsu

bje

cts

had

bee

nly

ing

on

each

dev

ice

for

30m

in(p<

0.00

1).

Th

ev

acu

um

spli

nt

was

also

fast

erto

app

ly(p<

0.00

1).

Vac

uu

msp

lin

tsp

rov

ided

bet

ter

im-

mo

bil

izat

ion

of

the

tors

oan

dle

sssl

ipp

age

on

ag

rad

ual

late

ral

tilt

.T

he

rig

idb

ack

bo

ard

wit

hh

ead

blo

cks

was

slig

htl

yb

ette

rat

imm

ob

iliz

ing

the

hea

d;

Vac

uu

msp

lin

tso

ffer

asi

gn

ifi-

can

tim

pro

vem

ent

inco

mfo

rto

ver

the

trad

itio

nal

bac

kb

oar

dfo

rth

ep

atie

nt

wit

hp

oss

ible

spin

alin

jury

.

Kre

llet

al.,

2006

Pre

ho

sp.

Em

erg

.C

are

Co

mp

aris

on

of

the

Fer

no

Sco

op

stre

tch

erw

ith

the

lon

gb

ack

bo

ard

for

spin

alim

mo

bil

iza-

tio

n

(Ex

per

imen

tal)

Po

pu

lati

on

:A

ge¼

26y

(18–

47y

);H

eig

ht¼

175

cm(1

55–

196

cm);

Wei

gh

t¼79

kg

(48–

121

kg

).T

rea

tme

nt:

Th

em

ov

emen

to

fth

esp

ine

du

rin

gim

mo

bil

izat

ion

and

lift

ing

bet

wee

nth

eF

ern

oS

coo

pS

tret

cher

Mo

del

65E

XL

(FS

S)

and

the

lon

gb

ack

bo

ard

(LB

B)

wer

eev

al-

uat

ed.

Eac

hd

evic

ew

asal

soev

alu

-at

edfo

rco

mfo

rtan

dse

nse

of

secu

rity

.O

utc

om

em

easu

res:

Sag

itta

l=la

tera

lfl

exio

nan

dax

ial

ro-

tati

on

RO

Mw

ere

mea

sure

do

nb

oth

the

LB

Ban

dF

SS

To

com

par

eth

etr

adit

ion

alL

BB

wit

hth

eF

SS

420

Th

ere

was

abo

ut

6–88

gre

ater

mo

tio

nin

the

sag

itta

l,la

tera

l,an

dax

ial

pla

nes

du

rin

gth

eap

pli

cati

on

of

the

LB

Bco

mp

ared

wit

hth

eF

SS

(p<

0.00

1).N

osi

gn

ifica

nt

dif

fere

nce

was

fou

nd

du

r-in

ga

secu

red

log

roll

man

euv

er.

Th

eF

SS

ind

uce

dm

ore

sag

itta

lfl

exio

nd

uri

ng

the

lift

than

the

LB

B(p<

0.00

1).

Th

eF

SS

sho

wed

sup

erio

rco

mfo

rtan

dp

erce

ived

secu

rity

ov

erth

eL

BB

.

Lu

sco

mb

ean

dW

illi

ams,

2003

Em

erg

.M

ed.

J.C

om

par

iso

no

fa

lon

gsp

inal

bo

ard

and

vac

uu

mm

attr

ess

for

spin

alim

mo

bi-

lisa

tio

n

(Ex

per

imen

tal)

Po

pu

lati

on

:M=F¼

8=1;

Wei

gh

tM=F¼

79k

g=58

kg

.T

rea

t-m

en

t:V

olu

nte

ers

wo

rea

Wiz

loc

rig

idce

rvic

alco

llar

and

stan

dar

d-

ized

clo

thin

g.

Eac

hw

asth

enp

lace

do

nb

oth

the

bac

kb

oar

dan

dth

ev

acu

um

mat

tres

san

dse

cure

lyst

rap

ped

toth

ed

evic

e.B

od

ym

ov

emen

tsan

dco

mfo

rtle

vel

sw

ere

det

erm

ined

.O

utc

om

em

easu

res:

Mea

nb

od

ym

ov

emen

tsan

dco

mfo

rtle

vel

s

To

com

par

eth

est

abil

ity

and

com

fort

affo

rded

by

the

lon

gsp

inal

bo

ard

and

the

vac

uu

mm

at-

tres

s

421

Th

em

ean

bo

dy

mo

vem

ents

inth

eh

ead

-u

pp

osi

tio

n,

hea

d-d

ow

np

osi

tio

n,

and

late

ral

tilt

wer

esi

gn

ifica

ntl

yg

reat

ero

nth

eb

ack

bo

ard

than

on

the

vac

uu

mm

attr

ess

(p<

0.01

).T

he

vac

uu

mm

at-

tres

sw

assi

gn

ifica

ntl

ym

ore

com

fort

-ab

leth

anth

eb

ack

bo

ard

(p<

0.01

).

1352

Page 13: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Mai

nan

dL

ov

ell,

1996

J.A

ccid

ent

Em

erg

.M

ed.

Are

vie

wo

fse

ven

sup

po

rtsu

rfac

esw

ith

emp

has

iso

nth

eir

pro

tect

ion

of

the

spin

ally

in-

jure

d.

(Ex

per

imen

tal

RC

T)

Tre

atm

en

t:S

ub

ject

sw

ere

ran

do

mly

pla

ced

on

six

wel

l-es

tab

lish

edsu

pp

ort

surf

aces

and

the

pro

toty

pe

sup

po

rtsu

rfac

e.R

ead

ing

sfo

rea

chsu

rfac

ew

ere

tak

enan

dth

em

ean

pre

ssu

res=

stan

dar

dd

evia

tio

ns

wer

eca

lcu

late

dto

mea

sure

the

var

i-ab

ilit

yo

fsa

cral

and

tho

raci

cp

ress

ure

sb

etw

een

the

sub

ject

san

dsu

rfac

es.

Th

esu

bje

cts

wer

eas

ked

abo

ut

com

fort

and

acce

pta

bil

ity

of

the

surf

aces

.O

utc

om

em

easu

res:

Mea

nsa

cral

and

tho

raci

cp

ress

ure

read

ing

s

To

eval

uat

ese

ven

evac

ua-

tio

nsu

pp

ort

surf

aces

:co

nv

enti

on

alsp

inal

bo

ard

,tw

ov

acu

um

stre

tch

ers,

ap

roto

typ

e(c

om

bin

atio

no

fb

oth

pri

nci

ple

s),

and

thre

eco

nv

enti

on

alst

retc

her

s

1B15

See

tex

t

Mar

uy

ama

etal

.,20

08B

r.J.

An

aes-

thes

iaR

and

om

ized

cro

ss-

ov

erco

mp

aris

on

of

cerv

ical

-sp

ine

mo

-ti

on

wit

hA

irw

ayS

cop

eo

rM

acin

tosh

lary

ng

osc

op

ew

ith

in-l

ine

stab

iliz

atio

n:

av

ideo

flu

oro

-sc

op

icst

ud

y

(Pro

spec

tiv

eR

CT

)P

op

ula

tio

n:

13p

atie

nts

wit

hn

orm

alce

rvic

alsp

ines

.T

rea

t-m

en

t:P

atie

nts

un

der

wen

tla

ryn

go

s-co

py

wit

ha

Mac

into

shb

lad

eo

ran

Air

way

sco

pe,

then

vic

ev

ersa

.O

ut-

com

em

easu

res:

Up

per

cerv

ical

spin

em

oti

on

asse

ssed

wit

hli

ve

vid

eofl

uo

-ro

sco

py

inth

ela

tera

lp

lan

e

To

com

par

eth

eC

-sp

ine

mo

vem

ent

req

uir

edfo

rla

ryn

go

sco

py

and

intu

-b

atio

nw

ith

the

Air

way

Sco

pe

and

the

Mac

into

shla

ryn

go

sco

pe

1B30

C-s

pin

em

oti

on

was

sig

nifi

can

tly

less

wit

hu

seo

fth

eA

irw

ayS

cop

eco

m-

par

edto

dir

ect

lary

ng

osc

op

yw

ith

the

Mac

into

shb

lad

e.T

ime

toin

tub

atio

nw

assi

mil

ar.

Maz

ole

wsk

ian

dM

anix

,19

94

An

n.

Em

erg

.M

ed.

Th

eef

fect

iven

ess

of

stra

pp

ing

tech

-n

iqu

esin

spin

alim

mo

bil

izat

ion

(Ex

per

imen

tal)

Po

pu

lati

on

:H

eig

ht:

70.2

0in

;W

eig

ht:

171.

74lb

;%

100.

Tre

atm

en

t:S

ub

ject

sre

stra

ined

on

aw

oo

den

bac

kb

oar

du

sin

ga

con

tro

lan

dth

ree

stra

pp

ing

tech

niq

ues

:#1

(co

ntr

ol)

—tw

ost

rap

so

ver

the

ches

tw

ith

ath

ird

stra

pp

lace

dju

stb

elo

wth

eax

illa

;#2

—th

esa

me

stra

ps

as#1

wit

han

abd

om

inal

stra

pac

ross

the

um

bil

icu

s;#3

—th

esa

me

stra

ps

as#2

,w

ith

ast

rap

aro

un

dth

ech

est=

arm

s;#4

—n

ocr

oss

stra

ps,

bu

tab

do

mi-

nal=ar

mst

rap

s.T

he

bac

kb

oar

dw

asro

lled

908

and

late

ral

mo

tio

no

fth

eto

rso

was

mea

sure

d.

Vo

lun

teer

sju

dg

edea

seo

fb

reat

hin

go

nce

the

stra

ps

wer

eti

gh

ten

ed,

and

each

was

ask

edw

hic

hm

eth

od

they

tho

ug

ht

allo

wed

the

leas

tam

ou

nt

of

late

ral

mo

tio

n.

Ou

tco

me

me

asu

res:

late

ral

mo

tio

n

To

test

the

effe

ctiv

enes

so

fst

rap

pin

gte

chn

iqu

esin

red

uci

ng

late

ral

mo

tio

no

fv

olu

nte

ers

rest

rain

edo

na

bac

kb

oar

d

1B15

Tec

hn

iqu

e#2

,w

hic

had

ded

anab

do

mi-

nal

stra

pto

the

con

tro

lte

chn

iqu

e,re

du

ced

26%

of

the

late

ral

mo

tio

n.

Tec

hn

iqu

es#2

,#3

,an

d#4

wer

efo

un

dto

be

stat

isti

call

ysi

gn

ifica

ntl

yd

iffe

ren

tth

ante

chn

iqu

e#1

,b

ut

no

tfr

om

each

oth

er(p<

0.05

).W

hen

ask

edw

hic

hte

chn

iqu

eth

eyth

ou

gh

tre

du

ced

late

ral

mo

tio

nb

est,

6%o

fv

olu

nte

ers

cho

sete

chn

iqu

e#1

,6%

tech

niq

ue

#2,

73%

tech

niq

ue

#,an

d15

%te

chn

iqu

e#4

.

McG

uir

eet

al.,

1987

J.T

rau

ma

Sp

inal

inst

abil

ity

and

the

log

roll

ing

ma-

no

euv

re

(Cas

ere

por

ts)

Tre

atm

en

t:T

he

mo

tio

no

fth

eth

ora

colu

mb

arsp

ine

ina

vo

lun

teer

wit

ha

stab

lesp

ine,

aca

dav

erw

ith

au

nst

able

tho

raco

lum

bar

spin

e,an

da

pat

ien

tw

ith

aT

12–L

1fr

actu

red

islo

-ca

tio

nw

ere

rad

iog

rap

hic

ally

exam

-in

ed.

Ou

tco

me

me

asu

res:

Sta

bil

izat

ion

effi

cien

cy

To

eval

uat

eth

em

oti

on

of

the

tho

raco

lum

bar

spin

ein

var

iou

sin

div

idu

als

412

Bo

thth

eb

ack

bo

ard

and

the

sco

op

stre

tch

ero

ffer

edad

equ

ate

stab

iliz

a-ti

on

for

thro

raco

lum

bar

spin

ein

sta-

bil

ity

.T

he

log

roll

man

euv

erp

rese

nte

dth

eg

reat

est

po

ssib

ilit

yfo

rm

ov

emen

to

fth

esp

ine

atth

eu

nst

able

tho

raco

-lu

mb

arse

gm

ent.

(Con

tin

ued

)

1353

Page 14: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Ta

bl

e1.

Ev

id

en

ce

Ta

bl

e(C

on

tin

ue

d)

Ref

eren

ceJo

urn

alT

itle

Des

ign

Pu

rpos

e=h

yp

oth

esis

Sac

kett

rati

ng

aD

&B

scor

e(o

ut

of44

)R

esu

lts

Mel

do

net

al.,

1998

J.T

rau

ma

Ou

to

fh

osp

ital

cerv

i-ca

lsp

ine

clea

ran

ce:

Ag

reem

ent

be-

twee

nem

erg

ency

med

ical

tech

nic

ian

san

dem

erg

ency

ph

ysi

cian

s

(Cas

ese

ries

)P

op

ula

tio

n:

Ag

34y

(6–9

8y

);%

59.

Tre

atm

en

t:P

atie

nt

dat

aw

ere

pro

spec

tiv

ely

coll

ecte

din

ord

erto

det

erm

ine

inte

r-ra

ter

agre

e-m

ent

bet

wee

nE

MT

san

dE

Ps

reg

ard

-in

go

ut-

of-

ho

spit

alcl

inic

alC

SI

clea

ran

ce.

Ou

tco

me

me

asu

res:

Inte

r-ra

ter

agre

emen

tb

etw

een

EM

Ts

and

EP

s

To

det

erm

ine

agre

emen

tb

etw

een

EM

Ts

and

EP

sw

hen

app

lyin

gan

EM

S=fi

red

epar

tmen

tp

roto

col

for

ou

t-o

f-h

os-

pit

alC

SI

clea

ran

cein

blu

nt

trau

ma

pat

ien

ts

427

Ov

eral

ld

isag

reem

ent

bet

wee

nE

MT

san

dE

Ps

reg

ard

ing

CS

Ip

re-h

osp

ital

clea

r-an

ceo

ccu

rred

in23

%o

fp

atie

nts

(kap

pa¼

0.29

;95

%C

I0.

15,

0.43

;p<

0.01

).C

SI

was

det

ecte

din

2.6%

of

pat

ien

ts,

and

all

of

them

wer

eim

mo

-b

iliz

edin

the

ou

t-o

f-h

osp

ital

sett

ing

.

Mu

hr

etal

.,19

98P

reh

osp

.E

mer

g.

Car

eP

aram

edic

use

of

asp

inal

inju

rycl

ear-

ance

alg

ori

thm

re-

du

ces

spin

alim

mo

bil

izat

ion

inth

eo

ut

of

ho

spit

alse

ttin

g

(Cas

ese

ries

)P

op

ula

tio

n:

Ag

e:st

an-

dar

34.1

y;

%M=F

:st

an-

dar

48=52

.T

rea

tme

nt:

Par

amed

ics

rece

ived

trai

nin

go

nth

eal

go

rith

m.

Th

eyw

ere

inst

ruct

edto

asse

ssp

a-ti

ent

lev

elo

fco

nsc

iou

snes

s,d

rug=

alco

ho

lu

se,

loss

of

con

scio

usn

ess,

spin

alp

ain=te

nd

ern

ess,

neu

rolo

gic

ald

efici

t,co

nco

mit

ant

seri

ou

sin

jury

,an

dp

ain

wit

hR

OM

.If

all

crit

eria

wer

en

egat

ive,

the

alg

ori

thm

ind

i-ca

ted

that

pat

ien

tsd

idn

’tn

eed

spin

alim

mo

bil

izat

ion

(SI)

.P

aram

edic

sco

mp

lete

da

trac

kin

gfo

rman

dfo

l-lo

wed

the

pat

ien

tto

the

ED

.D

ata

wer

eth

eng

ath

ered

tod

eter

min

eth

ep

rese

nce

of

spin

alfr

actu

re,

neu

ro-

log

ical

defi

cit,

or

aco

mb

inat

ion

of

the

two

To

det

erm

ine

wh

eth

erp

aram

edic

sca

nsa

fely

use

asp

inal

clea

ran

ceal

go

rith

mto

red

uce

un

-n

eces

sary

SI

inth

eo

ut-

of-

ho

spit

alse

ttin

g

421

11.7

%o

fp

atie

nts

wer

eim

mo

bil

ized

de-

spit

eth

eir

no

tm

eeti

ng

imm

ob

iliz

atio

ncr

iter

ia.

No

ne

of

thes

ep

atie

nts

wer

ed

iag

no

sed

ash

avin

gsp

inal

inju

ry.

Co

mp

aris

on

of

pre

-stu

dy

dat

aan

dst

ud

yd

ata

ind

icat

eda

33%

red

uct

ion

inu

tili

zati

on

of

SI

(95%

CI

27.2

,38

.8).

An

ou

t-o

f-h

osp

ital

spin

alcl

eara

nce

alg

ori

thm

adm

inis

tere

db

yp

aram

ed-

ics

can

red

uce

SI

by

on

e-th

ird

.

Ny

pav

eran

dT

relo

ar,

1993

An

n.

Em

erg

.M

ed.

Neu

tral

cerv

ical

spin

ep

osi

tio

nin

gin

chil

-d

ren

(Ex

per

imen

tal)

Po

pu

lati

on

:A

ge¼

33m

on

ths

(1m

on

th–7

y).

Tre

atm

en

t:T

he

two

ob

serv

ers

ind

epen

den

tly

pla

ced

chil

dre

nin

an

eutr

alp

osi

tio

nu

sin

gst

and

ard

-siz

edp

add

ing

wit

ho

rw

ith

-o

ut

shim

sto

rais

eth

eb

ack

off

ab

ack

bo

ard

.O

utc

om

em

easu

res:

Inte

r-o

bse

rver

agre

emen

t,h

eig

ht

of

elev

a-ti

on

To

det

erm

ine

the

elev

atio

no

fb

ack=sh

ou

lder

sn

eed

edto

pu

tch

ild

ren

inn

eutr

alce

rvic

alsp

ine

po

siti

on

,an

dd

eter

min

eif

ob

serv

ers

cou

ldag

ree

on

the

hei

gh

tre

qu

ired

420

Th

ein

ter-

ob

serv

erag

reem

ent

kap

-p

0.56

.N

oco

rrel

atio

nw

asn

ote

db

etw

een

the

age

and

hei

gh

to

fel

eva-

tio

n(r¼

0.11

4,p>

0.05

).W

hen

chil

-d

ren>

4y

old

wer

eco

mp

ared

wit

hth

ose�

4y

old

,it

was

fou

nd

that

the

yo

un

ger

gro

up

req

uir

edm

ore

elev

a-ti

on

for

corr

ect

po

siti

on

ing

than

old

erch

ild

ren

(p<

0.05

).

Pee

ryet

al.,

2007

Pre

ho

sp.

Em

erg

.C

are

Pre

-ho

spit

alsp

inal

imm

ob

iliz

atio

nan

dth

eB

ack

bo

ard

Qu

alit

yA

sses

s-m

ent

Stu

dy

(Cas

ese

ries

)P

op

ula

tio

n:

M=F¼

23=26

;W

eig

ht¼

172

lb;

Hei

gh

t¼68

in.

Tre

atm

en

t:P

atie

nts

wh

ow

ere

spi-

nal

lyim

mo

bil

ized

wer

eev

alu

ated

for

the

nu

mb

eran

do

ccas

ion

of

rest

rain

-in

gst

rap

san

dth

eir

deg

ree

of

tig

htn

ess

toas

sess

qu

alit

yo

fim

mo

bil

izat

ion

.O

utc

om

em

easu

res:

Nu

mb

eran

dlo

-ca

tio

no

fre

stra

inin

gst

rap

san

dth

eir

deg

ree

of

tig

htn

ess

To

qu

anti

fyh

ow

oft

enim

-m

ob

iliz

atio

nis

inad

e-q

uat

e

425

30%

had

atle

ast

on

eu

nat

tach

edst

rap

or

pie

ceo

fta

pe

that

sho

uld

hav

eat

tach

edth

eir

hea

dto

the

bo

ard

;88

%w

ere

fou

nd

toh

ave>

2cm

of

slac

kb

etw

een

thei

rb

od

yan

dat

leas

to

ne

stra

p;

amo

ng

tho

sew

ith

any

stra

ps

loo

ser

than

2cm

,th

eav

erag

en

um

ber

of

loo

sest

rap

sw

as3.

4.

1354

Page 15: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Per

ryet

al.,

1999

Sp

ine

Th

eef

fica

cyo

fh

ead

imm

ob

iliz

atio

nte

chn

iqu

esd

uri

ng

sim

ula

ted

veh

icle

mo

tio

n

(Ex

per

imen

tal)

Po

pu

lati

on

:A

ge¼

25y

;H

eig

ht¼

168

cm;

Wei

gh

t¼69

kg

.T

rea

tme

nt:

Th

ree

dif

fere

nt

hea

d-

imm

ob

iliz

atio

nm

eth

od

sw

ere

com

par

edin

six

hea

lth

yad

ult

su

sin

ga

com

pu

ter-

con

tro

lled

pla

tfo

rmto

sim

ula

tem

ov

emen

tsth

ato

ccu

rd

uri

ng

tran

spo

rt;

5=6

vo

lun

teer

sw

ere

test

edu

sin

gea

cho

fth

eth

ree

dif

fere

nt

met

ho

ds:

(1)

tow

els,

(2)

wed

ges

,an

d(3

)h

ead

bed

;1

vo

lun

teer

was

test

edo

nth

efi

rst

two

met

ho

ds;

3v

olu

nte

ers

wer

ete

sted

for

8m

in(4

exp

osu

res

for

2m

inea

ch),

and

the

oth

erth

ree

for

14m

in(7

exp

osu

res

for

2m

inea

ch).

Ou

tco

me

me

asu

res:

Effi

cacy

of

hea

dim

mo

bil

izat

ion

To

com

par

eth

eef

fica

cyo

fd

iffe

ren

th

ead

-im

mo

bil

i-za

tio

nte

chn

iqu

esd

uri

ng

mo

tio

nsi

mu

lati

ng

am-

bu

lan

cetr

ansp

ort

430

Th

era

ng

eo

fla

tera

lb

end

ing

was

sig

nif

-ic

antl

yla

rger

wh

enth

ism

oti

on

was

refe

ren

ced

toth

etr

un

kra

ther

than

toth

efr

actu

reb

oar

d(p<

0.00

1);

Sty

ro-

foam

wed

ges

led

toco

nsi

sten

tly

low

erra

ng

eso

fm

oti

on

for

abso

lute

axia

lro

tati

on

(p¼

0.00

04)

and

abso

lute

lat-

eral

ben

din

g(p¼

0.01

6)th

anth

eH

ead

bed

;T

her

ew

ere

no

stat

isti

call

ysi

gn

ifica

nt

dif

fere

nce

sb

etw

een

the

tech

niq

ues

inte

rms

of

rela

tiv

em

oti

on

occ

urr

ing

acro

ssth

en

eck

(ax

ial

rota

-ti

on

0.13

;la

tera

lb

end

ing

0.31

).

Sah

ni

etal

.,19

97P

reh

osp

.E

mer

g.

Car

eP

aram

edic

eval

uat

ion

of

clin

ical

ind

ica-

tors

of

cerv

ical

spi-

nal

inju

ry

(Ex

per

imen

tal)

Po

pu

lati

on

:H

ealt

hy

vo

l-u

nte

ers.

Tre

atm

en

t:T

he

EP

san

dE

MS

sw

ere

pai

red

.E

ach

pai

rev

alu

-at

edfi

ve

ran

do

mly

assi

gn

edp

atie

nts

for

six

clin

ical

crit

eria

:al

tera

tio

nin

con

scio

usn

ess,

evid

ence

of

into

xic

a-ti

on

,co

mp

lain

to

fn

eck

pai

n,

cerv

ical

ten

der

nes

s,n

euro

log

icd

efici

t=co

mp

lain

t,an

dd

istr

acti

ng

inju

ry.

Ifan

ycr

iter

ion

was

po

siti

ve,

clin

ical

clea

ran

cew

asco

nsi

der

edto

hav

efa

iled

and

the

pat

ien

tw

ou

ldh

ave

bee

nim

mo

bil

ized

.O

utc

om

em

ea

-su

res:

Kap

pa

coef

fici

ents

To

com

par

ep

aram

edic

as-

sess

men

tso

fin

dic

ato

rso

fce

rvic

alsp

inal

inju

ryw

ith

tho

seo

fat

ten

din

gem

erg

ency

ph

ysi

cian

s

416

Kap

pas

for

the

six

crit

eria

wer

e:al

tere

dco

nsc

iou

snes

0.77

;in

tox

ica-

tio

0.68

;n

eck

pai

0.62

;ce

rvic

alte

nd

ern

ess¼

0.73

;n

euro

log

icd

efi-

cit¼

0.68

;an

dd

istr

acti

ng

inju

ry¼

0.62

.K

app

0.90

for

the

imm

ob

iliz

atio

nd

ecis

ion

.In

on

eca

seth

ed

ecis

ion

sd

iffe

red

:th

ep

aram

edic

ind

icat

edim

-m

ob

iliz

atio

n,

wh

erea

sth

ep

hy

sici

ans

did

no

t.N

op

atie

nt

req

uir

ing

imm

o-

bil

izat

ion

wo

uld

hav

eb

een

clin

ical

lycl

eare

db

yth

ep

aram

edic

s.

Sca

nn

ell

etal

.,19

93A

rch

.S

urg

.O

rotr

ach

eal

intu

ba-

tio

nin

trau

ma

pa-

tien

tsw

ith

cerv

ical

frac

ture

s

(Cas

ese

ries

)T

rea

tme

nt:

Sen

ior

resi

den

to

rfa

cult

yan

esth

esio

log

ists

per

form

edin

tub

atio

ns.

Per

iph

eral

neu

rolo

gic

alex

amin

atio

nw

asp

erfo

rmed

bef

ore

and

afte

rea

chin

tub

atio

n,

and

neu

ro-

log

ical

defi

cits

wer

ed

ocu

men

ted

Ou

tco

me

me

asu

res:

Nu

mb

ero

fn

eu-

rolo

gic

defi

cits

To

eval

uat

eo

rotr

ach

eal

in-

tub

atio

nw

ith

in-l

ine

stab

iliz

atio

no

fth

ece

r-v

ical

spin

efo

rem

er-

gen

cyai

rway

trea

tmen

to

fp

atie

nts

48

Th

ere

wer

eu

nst

able

cerv

ical

frac

ture

sin

38p

atie

nts

wit

hn

on

euro

log

ical

def

-ic

its,

and

23p

atie

nts

wer

en

euro

log

i-ca

lly

inta

ctw

ith

frac

ture

sth

atw

ere

late

rju

dg

edst

able

.In

no

inst

ance

was

ther

ea

det

erio

rati

on

of

neu

rolo

gic

alst

atu

sfo

llo

win

gin

tub

atio

n.

Per

iph

eral

neu

rolo

gic

ald

efici

tsim

pro

ved

afte

rin

tub

atio

nin

fou

rp

atie

nts

.

Sch

aefe

rmey

er,

etal

.,19

91A

nn

.E

mer

g.

Med

.R

esp

irat

ory

effe

cts

of

spin

alim

mo

bil

iza-

tio

nin

chil

dre

n

(Ex

per

imen

tal)

Po

pu

lati

on

:A

ge¼

10.6

y;

M=F¼

22=29

;H

eig

ht¼

57.5

in.

Tre

at-

me

nt:

Par

tici

pan

ts’

forc

edv

ital

cap

ac-

ity

(FV

C)

mea

sure

men

tsw

ere

firs

to

bta

ined

wit

hch

ild

ren

stan

din

gan

dly

ing

sup

ine,

and

then

infu

llsp

inal

imm

ob

iliz

atio

nu

sin

gtw

od

iffe

ren

tst

rap

pin

gco

nfi

gu

rati

on

s:cr

oss

stra

ps

and

late

ral

stra

ps.

Str

aps

wer

eti

gh

t-en

edto

allo

wo

ne

han

dto

fit

snu

gly

bet

wee

nth

est

rap

and

the

chil

d.

Ou

t-co

me

me

asu

res:

Su

pin

eF

VC

To

asse

ssth

ere

stri

ctiv

eef

-fe

cts

of

two

spin

alim

-m

ob

iliz

atio

nst

rap

pin

gte

chn

iqu

eso

nth

ere

spi-

rato

ryca

pac

ity

of

no

r-m

alh

ealt

hy

chil

dre

n

419

Su

pin

eF

VC

was

less

than

up

rig

ht

FV

C(p<

0.00

1).

FV

Cin

spin

alim

mo

bil

i-za

tio

nra

ng

edfr

om

41–9

6%o

fsu

pin

eF

VC

.T

her

ew

asn

od

iffe

ren

cein

FV

Cb

etw

een

stra

pp

ing

tech

niq

ues

(p¼

0.83

).S

pin

alim

mo

bil

izat

ion

sig

-n

ifica

ntl

yre

du

ced

resp

irat

ory

cap

acit

yas

mea

sure

db

yF

VC

inh

ealt

hy

pa-

tien

ts6–

15y

old

.T

her

ew

asn

osi

gn

if-

ican

tb

enefi

to

fo

ne

stra

pp

ing

tech

niq

ue

ov

erth

eo

ther

.

(Con

tin

ued

)

1355

Page 16: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Ta

bl

e1.

Ev

id

en

ce

Ta

bl

e(C

on

tin

ue

d)

Ref

eren

ceJo

urn

alT

itle

Des

ign

Pu

rpos

e=h

yp

oth

esis

Sac

kett

rati

ng

aD

&B

scor

e(o

ut

of44

)R

esu

lts

Sch

rig

eret

al.,

1991

An

n.

Em

erg

.M

ed.

Sp

inal

imm

ob

iliz

atio

no

na

flat

bac

kb

oar

d:

Do

esit

resu

ltin

neu

tral

po

siti

on

of

the

cerv

ical

spin

e?

(Ex

per

imen

tal)

Po

pu

lati

on

:M=

50=50

;A

ge¼

24.4

y.

Tre

atm

en

t:N

eutr

alp

osi

tio

nw

asd

efin

edas

the

no

rmal

anat

om

icp

osi

tio

no

fth

eh

ead

and

tors

oth

ato

ne

assu

mes

wh

enst

and

ing

loo

kin

gst

raig

ht

ahea

dO

utc

om

em

easu

res:

Intr

a-o

bse

rver

reli

abil

ity

,o

ccip

ital

off

set

To

det

erm

ine

the

amo

un

to

fo

ccip

ital

pad

din

gre

-q

uir

edto

ach

iev

en

eutr

alp

osi

tio

no

fth

ece

rvic

alsp

ine

wh

enim

mo

bil

ized

on

afl

atb

ack

bo

ard

423

Intr

a-o

bse

rver

reli

abil

ity

sho

wed

am

ult

i-o

bse

rver

kap

pa¼

0.99

and

intr

a-cl

ass

corr

elat

ion

coef

fici

ent

of

0.98

.T

he

amo

un

to

fo

ccip

ital

off

set

req

uir

edfo

rn

eutr

alp

osi

tio

nv

arie

dfr

om

0–3.

75in

(mea

1.49

in;

95%

CI

1.37

,1.

60).

Mea

no

ccip

ital

off

set

for

men

(1.6

7in

)w

assi

gn

ifica

ntl

yg

reat

erth

anth

atfo

rw

om

en(1

.31

in;

0.00

16).

Mea

no

ccip

ital

off

set

sig

nifi

can

tly

dif

-fe

red

fro

mze

ro(p<

0.00

01).

Bo

dy

mea

sure

men

tsd

idn

ot

accu

rate

lyp

red

ict

occ

ipit

alo

ffse

t.Im

mo

bil

izat

ion

on

afl

atb

ack

bo

ard

wo

uld

pla

ce98

%o

fsu

bje

cts

ince

rvic

alex

ten

sio

n.

Occ

i-p

ital

pad

din

gw

ou

ldp

lace

ag

reat

erp

erce

nta

ge

of

pat

ien

tsin

neu

tral

po

si-

tio

nan

din

crea

sep

atie

nt

com

fort

.

Sh

eeri

nan

dd

eF

rein

,20

07J.

Em

erg

.N

urs

.T

he

occ

ipit

alan

dsa

-cr

alp

ress

ure

sex

-p

erie

nce

db

yh

ealt

hy

vo

lun

teer

su

nd

ersp

inal

im-

mo

bil

izat

ion

:a

tria

lo

fth

ree

surf

aces

(RC

T)

Po

pu

lati

on

:A

ge¼

41an

d23

y;

2;W

eig

ht¼

82an

d67

kg

;H

eig

ht¼

1.68

and

1.77

m;

BM

I¼29

.05

and

21.3

9k

g=m

2.

Tre

atm

en

t:T

he

two

vo

lun

teer

sw

ere

imm

ob

iliz

edo

nth

ree

spin

alsu

pp

ort

surf

aces

toas

sess

the

dif

fere

nce

sin

occ

ipit

alan

dsa

cral

tiss

ue

inte

rfac

ep

ress

ure

.Ou

tco

me

me

asu

res:

Red

uct

ion

of

pre

ssu

reex

per

ien

ced

atth

eo

ccip

ital

and

sacr

alre

gio

ns

To

iden

tify

wh

eth

ero

rn

ot

the

pre

ssu

reex

per

ien

ced

by

ind

ivid

ual

sat

two

anat

om

ical

loca

tio

ns

wer

ed

epen

den

to

nth

esu

pp

ort

surf

ace

use

d

2B20

See

tex

t

Str

oh

and

Bra

ud

e,20

01A

nn

.E

mer

g.

Med

.C

anan

ou

t-o

f-h

osp

i-ta

lce

rvic

alsp

ine

clea

ran

cep

roto

col

iden

tify

all

pat

ien

tsw

ith

inju

ries

?A

nar

gu

men

tfo

rse

lec-

tiv

eim

mo

bil

izat

ion

(Ret

rosp

ecti

ve

char

tre

vie

w)

Po

pu

lati

on

:86

1p

atie

nts

wit

hsi

gn

ifica

nt

cerv

ical

inju

ries

dis

char

ged

fro

mfi

ve

trau

ma

ho

spit

als

bet

wee

nJu

ly1,

1990

and

Jun

e30

,19

96

To

det

erm

ine

the

sen

siti

v-

ity

of

anE

MS

spin

eim

-m

ob

iliz

atio

np

roto

col

inid

enti

fyin

gp

atie

nts

wit

hce

rvic

alin

juri

es,

and

tod

eter

min

ew

het

her

itw

assa

fein

ano

ut-

of-

ho

spit

alse

ttin

g

423

Of

the

861

tota

lpat

ien

ts,5

04w

ere

bro

ug

ht

toh

osp

ital

by

EM

S,w

ith

495

arri

vin

gin

spin

eim

mo

bil

izat

ion

.T

he

EM

Ssp

inal

imm

ob

iliz

atio

np

roto

col

was

99%

sen

-si

tiv

ein

iden

tify

ing

pat

ien

tsw

ith

sig

-n

ifica

nt

cerv

ical

inju

ries

for

imm

ob

iliz

atio

n.

Pro

spec

tiv

ev

alid

atio

nad

dre

ssin

gli

mit

atio

ns

isn

eed

ed.

Tu

rkst

raet

al.,

2005

An

esth

.A

nal

g.

Cer

vic

alsp

ine

mo

-ti

on

:a

flu

oro

sco

pic

com

par

iso

nd

uri

ng

intu

bat

ion

wit

hli

gh

ted

sty

let,

Gli

deS

cop

e,an

dM

acin

tosh

lary

ng

osc

op

e

(Pro

spec

tive

RC

Tcr

oss-

over

)P

op

ula

tio

n:

AS

AI–

III,

elec

tiv

en

on

card

iac

surg

ery

,w

ith

ou

td

iffi

cult

airw

ayo

ru

nst

able

C-

spin

e.T

rea

tme

nt:

Lig

htw

and

ver

sus

Mac

into

sh(n¼

18),

and

Gli

deS

cop

ev

ersu

sM

acin

tosh

(n¼

18),

all

wit

hsi

mu

late

dm

anu

alin

-lin

eim

mo

bil

iza-

tio

n.

Ou

tco

me

me

asu

res:

Ex

ten

sio

n-

flex

ion

of

nec

ku

nd

erd

igit

alv

ideo

flu

oro

sco

py

To

det

erm

ine

C-s

pin

em

ov

emen

td

uri

ng

use

of

the

Gli

deS

cop

eo

rL

igh

t-w

and

ver

sus

dir

ect

lar-

yn

go

sco

py

wit

hth

eM

acin

tosh

bla

de

1B30

C-s

pin

em

oti

on

was

sig

nifi

can

tly

less

du

rin

gb

ag-a

nd

-mas

kv

enti

lati

on

than

dir

ect

lary

ng

osc

op

y.

Lig

htw

and

use

resu

lted

insi

gn

ifica

ntl

yle

ssC

-sp

ine

mo

tio

nal

on

gal

lse

gm

ents

,fr

om

occ

ipit

al-c

erv

ical

toce

rvic

oth

ora

cic

reg

ion

s(p<

0.03

).G

lid

eSco

pe

use

resu

lted

inre

du

ced

mo

tio

nfr

om

C2–

C5,

bu

tn

och

ang

ein

mo

tio

nat

oth

erre

gio

ns

ver

sus

the

Mac

into

shb

lad

e.T

ime

toin

tub

atio

nw

assi

mil

arfo

rth

eL

igh

twan

dan

dth

eb

lad

e,b

ut

was

incr

ease

dw

ith

the

use

of

the

Gli

de-

Sco

pe

ver

sus

the

bla

de

(p<

0.01

).

1356

Page 17: Pre-Hospital Care Management of a Potential Spinal Cord ... · PDF fileDavies et al., 1996; De Lorenzo et al., 1996; Hamilton and Pons, 1996; Hauswald et al., 2000; Johnson et al.,

Wal

ton

etal

.,19

94A

cad

.E

mer

g.

Med

.P

add

edv

s.u

np

add

edsp

ine

bo

ard

for

cerv

ical

spin

eim

-m

ob

iliz

atio

n

(RC

T)

Po

pu

lati

on

:A

ge¼

32.5

y;

M=F¼

26=4;

Wei

gh

t¼72

kg

.T

rea

t-m

en

t:S

ub

ject

sw

ere

ran

do

miz

edto

eith

erp

add

edo

ru

np

add

edlo

ng

spin

eb

oar

dim

mo

bil

izat

ion

wit

hse

rial

mea

sure

men

tso

fd

isco

mfo

rtan

dtr

ansc

uta

neo

us

tiss

ue

ox

yg

ente

nsi

on

.T

he

sub

ject

sw

ere

then

ask

edto

retu

rnaf

ter

atle

ast

3d

ays

tob

eim

mo

bil

ized

wit

hth

eo

ther

spin

eb

oar

d.

Ou

tco

me

me

asu

re:

Dis

com

fort

,fl

exio

n,

exte

n-

sio

n,

rota

tio

n,

late

ral

ben

din

g,

and

sacr

altr

ansc

uta

neo

us

ox

yg

ente

nsi

on

To

det

erm

ine

wh

eth

erp

add

ing

the

lon

gsp

ine

bo

ard

imp

rov

esp

atie

nt

com

fort

,af

fect

sce

rvic

alsp

ine

imm

ob

iliz

atio

n,

or

incr

ease

ssa

cral

tran

scu

-ta

neo

us

ox

yg

ente

nsi

on

2B23

Su

bje

ctd

isco

mfo

rtw

assi

gn

ifica

ntl

yre

-d

uce

din

the

pad

ded

gro

up

com

par

edw

ith

the

un

pad

ded

gro

up

(p¼

0.02

4).

Th

ere

was

no

sig

nifi

can

td

iffe

ren

cein

flex

ion

(p¼

0.41

0),

exte

nsi

on

(p¼

0.23

1),

rota

tio

n(p¼

0.89

1),

or

late

ral

ben

din

g(p¼

0.23

0)fo

rth

etw

og

rou

ps.

Th

ere

was

no

sig

nifi

can

td

if-

fere

nce

inth

eac

tual

dro

pin

sacr

altr

ansc

uta

neo

us

ox

yg

ente

nsi

on

fro

mti

me

zero

to30

min

for

the

pad

ded

and

the

un

pad

ded

gro

up

s(p¼

0.90

6).

Wan

ing

eret

al.,

2001

Cli

n.

J.S

po

rtM

ed.

An

eval

uat

ion

of

hea

dm

ov

emen

tin

bac

k-

bo

ard

-im

mo

bil

ized

hel

met

edfo

otb

all,

lacr

oss

e,an

dic

eh

ock

eyp

lay

ers

(Pro

spec

tiv

e)P

op

ula

tio

n:

30v

olu

nte

erco

lleg

iate

ath

lete

s(1

2ic

eh

ock

ey,

9fo

otb

all,

9la

cro

sse)

wit

hn

oh

isto

ryo

fce

rvic

alsp

ine

inju

ryo

rp

ath

olo

gy

.T

rea

tme

nt:

Ath

lete

sw

ere

imm

ob

i-li

zed

on

bac

kb

oar

ds

per

pro

toco

l.T

hre

ere

tro

-refl

ecti

ve

mar

ker

sw

ere

atta

ched

toth

eh

elm

et.

Mea

sure

men

tsw

ere

ob

tain

edd

uri

ng

ap

erio

dw

hen

the

bac

kb

oar

dw

asp

ertu

rbed

ino

rder

tost

imu

late

jost

lin

gd

uri

ng

tran

spo

r-ta

tio

n.

Ou

tco

me

me

asu

res:

Hel

ical

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body tissue pressure (Chan et al., 1996; Hauswald et al., 2000;Main and Lovell, 1996; Sheerin and de Frein, 2007; Waltonet al., 1995); however, no study evaluated what constitutes asafe duration of immobilization on a hard board, althoughtissue interface pressures were elevated even after short pe-riods of rigid immobilization (Main and Lovell, 1996; Sheerinand de Frein, 2007; Walton et al., 1995). None of the studiesassessed time on hard board and the clinical outcome ofpressure sores. As a result, there is no firm time point citedin the literature after which immobilization should be dis-continued.

Main and Lovell (1996) performed an experimental ran-domized controlled trial in which subjects laid on six dif-ferent support surfaces and surface pressure readings wereobtained both at the sacral region and the thoracic region.Results showed that the traditional spinal board had thehighest sacral reading of 233.5 mm Hg and the highest tho-racic reading of 82.9 mm Hg, versus other forms of stretcherssuch as the York Two stretcher, for which readings of 46 mmHg and 21 mm Hg, respectively, were obtained. The studyalso found that the traditional board lacked support forthe lumbar lordosis. Differences in pressure readings inthe various board surfaces and designs may lead to differ-ences in the occurrence of pressure sores in the setting ofprolonged transportation times and SCI (Main and Lovell,1996).

Sheerin and de Frein (2007) conducted an experimentalstudy examining volunteers on different support surfaces andassessed occipital and sacral tissue interface pressures. Thehighest pressure readings were seen with the traditionalunpadded spinal board. They observed that occipital andsacral pressures were lowest with a vacuum mattress device(Sheerin and de Frein, 2007).

Mazolewski and Manix examined different techniques ofstrapping in spinal immobilization using an experimentalstudy in which subjects were restrained on a spine board.Four different techniques were evaluated and lateral spinemotion was measured as the backboard was rolled 908 fromside to side. Motion was most reduced by placing two strapsthat cross over at the chest, with a third strap placed across theumbilicus (Mazolewski and Manix, 1994).

Krell and colleagues compared the scoop stretcher to thelong backboard for spinal immobilization in terms of mo-tion and comfort. There were 6–88 more of sagittal motionduring the application of the long backboard compared to thescoop board. The scoop board was also perceived to be morecomfortable compared to the traditional board (Krell et al.,2006).

There are few published studies evaluating spinal immo-bilization for children. Only two of the identified publicationsstudied pediatric spinal immobilization (Nypaver and Tre-loar, 1994; Schafermeyer et al., 1991). There are anatomicdifferences between adults and children that may preventvalid generalizations of the adult literature to spinal immo-bilization in a pediatric population. These include increasedhead:body size ratio, as well as a more posterior occiput rel-ative to the spinal plumb line in children than in adults. Withthe relative paucity of literature evaluating pediatric immo-bilization, and the concerns regarding generalizability ofadult findings to this population, the group decided to restrictrecommendations made in this review to individuals over theage of 12 years.

Question 2. During airway manipulation in the pre-hospital setting, what is the ideal method of spinal immobi-lization?

Most studies examining airway management were per-formed in the hospital rather than in the pre-hospital setting(Doran et al., 1995; Maruyama et al., 2008; Scannell et al., 1993;Turkstra et al., 2005). Intubations in the studies were done bysenior anesthesia residents or fully-trained anesthesiologists.The studies did not assess intubations done by emergencymedical technicians in the field, and there was only one articleexamining pre-hospital intubation and factors influencingsuccessful intubation in the pre-hospital setting. This pro-spective study evaluated 4691 transported patients, of which236 required intubation. The intubation success rate was 88%,and was considered to be technically more challenging, es-pecially in the setting of spinal immobilization (Doran et al.,1995).

The available clinical studies evaluating the impact of air-way control using in-line cervical stabilization did not findworsening of neurologic status after airway management(Maruyama et al., 2008; Scannell et al., 1993). Anatomicalstudies of in-line stabilization with a Miller blade showed lesscervical movement compared to use of a cervical collar alone(Gerling et al., 2000).

Several randomized cross-over trials were performedassessing newer forms of indirect intubation in patients un-dergoing general anesthesia for elective surgeries with livefluoroscopy (Maruyama et al., 2008; Turkstra et al., 2005).Indirect methods of intubation such as the Lightwand withmanual in-line immobilization were found to cause less cer-vical motion than direct laryngoscopy with a Miller bladeand in-line immobilization (Maruyama et al., 2008; Turkstraet al., 2005).

Question 3. What is the impact of pre-hospital transporttime to definitive care on the outcomes of patients withacute SCI?

There is little evidence regarding the impact of pre-hospitaltransport time to definitive care on the outcomes of patientswith acute SCI. However, patients transported within 24 h fortreatment fared better than those transported after 24 h. It isunknown if there were confounding factors in those patientstransported after 24 h that negatively affected outcomes,such as medical comorbidities or concurrent injuries thathindered earlier transportation, and thus negatively impactedthe results of spinal cord injury treatment. Air and groundtransport are both safe when spinal precautions are taken fortransport (Armitage et al., 1990; Burney et al., 1989; Flabouris,2001), and these studies did not document the developmentof any ascending neurological deficits with transport (Armi-tage et al., 1990; Burney et al., 1989; Flabouris, 2001).

Burney and associates reviewed patients with spinal col-umn fractures with SCI (complete or incomplete) to assesswhether these patients could undergo safe early transport toan SCI center using basic equipment for spine stabilization.Transportation was achieved both by ground ambulance(41%) , helicopter (54%), and fixed-wing aircraft (5%), and84% were transferred within 24 h of injury. No patients suf-fered ascending injury levels as a result of transfer. There wasno significant difference found in the probability of im-provement between ground and air transportation (Burneyet al., 1989).

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Flabouris and colleagues reviewed the pattern of utilizationof a medically-staffed transportation service by patients withsuspected spinal injuries from a hospital or from a scene ofan accident and documented the impact of differentmodes of transportation. The majority (93%) of transferswere by helicopter, followed by fixed-wing aircraft (3.5%),and lastly road vehicles. Mean duration of inter-hospitaltransport (42� 28 min) was longer than from scene transfers(19� 12 min), but this was similar to road vehicle transfers(45� 26 min). Rural hospitals were the referral source for 55%of inter-hospital transports. The reason for 18% of all inter-hospital transfers was to exclude a spinal injury that could nototherwise be excluded at the referral hospital. No worseneurological outcomes occurred as a result of transportation(Flabouris, 2001).

Question 4. What is the role for pre-hospital care pro-viders in cervical spine clearance and immobilization?

Clinical evidence reveals that pre-hospital emergencymedical technicians can be trained to apply criteria to clearpatients of cervical spinal injuries and immobilize patientssuspected of having a cervical spinal injury to a level similar tothat of emergency physicians (Armstrong et al., 2007; Benneret al., 2006; Brown et al., 1998; Burton et al., 2005, 2006;Campbell, 1987; Domeier et al., 1997, 1999, 2002, 2005; Meldonet al., 1998; Muhr et al., 1999; Sahni et al., 1997; Stroh andBraude, 2001). There was no universal tool or triage indexused in the studies.

In some series up to 8% of vertebral column injuries werenot immobilized (Armstrong et al., 2007; Brown et al., 1998;Domeier et al., 2002, 2005; Stroh and Braude, 2001). However,there were no clinical consequences of not immobilizing, andnone of these column injuries had associated neurologicaldeficits (Armstrong et al., 2007; Brown et al., 1998; Domeieret al., 2002, 2005; Stroh and Braude, 2001).

Armstrong and associates examined whether the incidenceof unnecessary cervical spine immobilization by ambulancepersonnel could be safely reduced through the implementationof an evidence-based algorithm. Following a training program,paramedics collected data on 103 patients with potential cer-vical spine injuries, of which 69 (67%) had their cervical spinescleared at the accident scene. Of these, 60 (87%) were dis-charged at the scene with no clinical adverse events reported,and 9 (13%) were taken to the local emergency department withminor injuries, and all were discharged home the same day.However, 34 (33%) patients could not have their cervical spinessafely cleared at the scene according to the algorithm. Of these,4 (12%) patients self-discharged themselves at the scene, and30 (88%) were conveyed to an emergency department per theirprocedure protocol (Armstrong et al., 2007).

Brown and co-workers examined whether emergencymedical services (EMS) providers can accurately apply clini-cal criteria for clearing the cervical spine in trauma patients.Both emergency physicians and EMS providers indicatedimmobilization in 60% of patients, and their assessmentsdiffered for 21.3% of patients. Overall agreement indicated akappa value of 0.48, which reflects moderate agreement. TheEMS providers were generally more conservative than theemergency physicians (Brown et al., 1998).

Domeier and colleagues first examined prospectivelywhether or not retrospectively identified criteria could beused to identify patients without significant spinal fracture

outside of the hospital. By utilizing their criteria, 100% of allcervical injuries were identified. They identified 90% of pa-tients with thoracic injuries, and 96% of patients with lumbarinjuries. There were three false-negatives, of which two hadstable thoracic compression injuries, and one had a lumbartransverse fracture. Only one of these false-negatives wasadmitted to hospital for pain control, and was dischargedwithin 2 days, and the remaining false-negative injuries weredischarged from the emergency department. No significantspinal fractures were missed (Domeier et al., 1997).

In another study, Domeier and associates examined thereliability of a pre-hospital clinical evaluation tool in pa-tients with different severities and mechanisms of injury. Inall, 1059 patients were assessed in the high-risk group, ofwhich 9.4% had injuries, and 5423 low-risk group patientswere assessed, of which 2% had injuries. The criteria identi-fied 97% of injuries in the high-risk group, and 94% in thelow-risk group. The mechanism of injury did not affect theability of the clinical criteria to predict spinal injury (Domeieret al., 1999).

In 2005, Domeier and colleagues assessed whether theprotocols developed allowed EMS providers to appropriatelyimmobilize patients with spinal injuries. The sensitivity of theEMS protocol was 92% (95% CI 89.4, 94.6), and 8% of patientswith spinal injuries did not have immobilization; however,none of the non-immobilized patients sustained cord injuries.EMS providers also immobilized 12% of patients not requiredby the protocol. The use of the selective immobilization pro-tocol resulted in spine immobilization for most patients withspinal injury, without causing harm in cases in whom im-mobilization was withheld (Domeier et al., 2005).

Muhr and associates also examined training paramedics touse a clearance algorithm. If patients met all the criteria,paramedics could transport them without spine immobiliza-tion. They found that there was a 33% reduction in the utili-zation of spinal immobilization compared to pre-study data(Muhr et al., 1999).

Further research is needed to determine a universal triagesystem that can be implemented to train emergency medicaltechnicians in the pre-hospital setting. However, the resultsof the systematic review for this question must be balancedwith the realities of geographic variations in law and healthpolicy, and the varying risk tolerance of EMS systems in dif-ferent regions.

Recommendations

All recommendations were derived from the systematicreviews, statements from the authors, and the Delphi process.The latter was reported using the level of agreement and thecomments and suggestions of experts.

Question 1. What is the optimal type and duration of pre-hospital spinal immobilization in patients with acute SCI?

� Immobilization of patients with SCI during the pre-hospital setting should include a cervical collar, headimmobilization, and a spinal board.

� Patients should be transferred off the hardboard onadmission to a facility as soon as is feasible to minimizetime on the hardboard. If patients are awaiting transferto another institution, they should be taken off the hard-board while awaiting transfer.

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� Padded boards or inflatable bean bag boards should beutilized to reduce pressure on the occiput and sacrum.

� These recommendations are intended for adults andchildren over the age of 12 years.

Question 2. During airway manipulation in the pre-hospital setting, what is the ideal method of spinal immobi-lization?

� Airway management of acute SCI patients requiringintubation in the pre-hospital setting should include theuse of manual in-line cervical spine traction.

� Intubation of patients with acute SCI in the pre-hospitalsetting should not rely solely on cervical collar neckimmobilization.

� Indirect methods of intubation may cause less cervicalmovement than with direct laryngoscopy with a Millerblade.

Question 3. What is the impact of pre-hospital transporttime to definitive care on the outcomes of patients with acuteSCI?

� Transport of patients with acute traumatic SCI to thedefinitive hospital center for care should occur within24 h of injury.

Question 4. What is the role for pre-hospital care pro-viders in cervical spine clearance and immobilization?

� Emergency medical personnel in the pre-hospital settingcan be trained to apply criteria to clear patients of cer-vical spinal injuries and immobilize patients suspectedof having a cervical spinal injury.

� The implementation of this recommendation will likelybe impacted by regional variations in law and healthpolicy.

There is insufficient evidence to make recommendationsfor children, and the authors have concerns regarding theapplicability of adult recommendations to pediatric patients.

Summary

Pre-hospital care of patients with potential spinal cordinjury requires great care to minimize secondary SCI andpotential morbidity related to spinal immobilization. Thissystematic review provides an evidentiary table and a sum-mary of the review, in addition to recommended guidelinesbased on use of the Delphi method by a group of experts.

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Address correspondence to:Albert Yee, M.D., M.Sc., F.R.C.S.C.

Department of SurgeryUniversity of Toronto

2075 Bayview AvenueRoom MG-371

Toronto, Ontario M4N3M5, Canada

E-mail: [email protected]

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